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Dipress HL 50mg/5mg/12.5mg Tablet is used in the treatment of high blood pressure (hypertension). It dilates (widens) blood vessels and increases blood flow. It helps to lower blood pressure, reduce chest pain (angina), and other complications caused by coronary artery disease. Also, it removes extra water/fluid and certain electrolytes overload from the body. It may cause side effects such as nausea, altered taste, diarrhea, stomach upset, dizziness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, numbness (lost, reduced, or altered sensation) of extremity in some case. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MG

Manufacturer/Marketer :

Symbiosis Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Dipress HL 50mg/5mg/12.5mg Tablet

Dipress HL 50mg/5mg/12.5mg Tablet is a combination prescription medication used to treat high blood pressure (hypertension). It is typically prescribed when a patient requires more than two medications to keep their blood pressure within a healthy range. By lowering high blood pressure, this medication helps prevent serious cardiovascular events like strokes and heart attacks.

For the best results, you should take Dipress HL 50mg/5mg/12.5mg Tablet consistently once a day, at the same time every day. You can take this tablet with or without food, as it does not affect how the medicine is absorbed. Adopting healthy lifestyle habits, such as eating a low-sodium diet and engaging in regular moderate exercise, can significantly support the benefits of this medication.

While taking Dipress HL 50mg/5mg/12.5mg Tablet, some people may experience mild side effects like dizziness, lightheadedness, or slight ankle swelling. However, you must seek medical attention immediately if you experience severe dizziness, fainting, or signs of an allergic reaction. Talk to your doctor or pharmacist if any mild side effects persist or worsen over time.

Before starting this medication, talk to your doctor if you have a history of kidney disease, liver damage, diabetes, or severe heart problems. Do not take this if you are pregnant, as the active components can cause severe harm or death to an unborn baby. It is highly recommended to discuss alternative therapies with your healthcare provider if you plan to become pregnant.

This medication can interact with other blood pressure drugs, potassium supplements, and certain pain relievers, which can strain your kidneys. Avoid drinking alcohol while taking Dipress HL 50mg/5mg/12.5mg Tablet, as it can cause your blood pressure to drop too low, leading to severe dizziness. Elderly individuals and those who are breastfeeding should consult their doctor before starting this treatment.

Uses of Dipress HL 50mg/5mg/12.5mg Tablet

Dipress HL 50mg/5mg/12.5mg Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Dipress HL 50mg/5mg/12.5mg Tablet are as follows:

  • Hypertension (High Blood Pressure): Dipress HL 50mg/5mg/12.5mg Tablet helps lower severely high blood pressure in adults whose condition is not adequately managed by single or dual therapies.
  • Prevention of Stroke and Heart Attack: Maintaining healthy blood pressure levels reduces the workload on the heart and decreases the risk of life-threatening cardiovascular events.

Key Benefits

Dipress HL 50mg/5mg/12.5mg Tablet helps maintain healthy blood pressure levels and supports long-term cardiovascular health. By providing consistent blood pressure control throughout the day, it helps reduce strain on the heart and protects vital organs from the effects of uncontrolled hypertension. Benefits may include:

  • Helps lower and maintain healthy blood pressure levels.
  • Provides consistent 24-hour blood pressure control.
  • Helps reduce the risk of sudden increases in blood pressure.
  • Supports the health of vital organs such as the heart, brain, and kidneys.
  • Reduces the risk of complications associated with uncontrolled high blood pressure, including heart attack and stroke.
  • Simplifies treatment by combining multiple blood pressure-lowering medicines in a single tablet.

Directions for Use

  • Take Dipress HL 50mg/5mg/12.5mg Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Dipress HL 50mg/5mg/12.5mg Tablet Works

Dipress HL 50mg/5mg/12.5mg Tablet contains Amlodipine, Losartan, and Hydrochlorothiazide. • Amlodipine: It helps relax and widen the blood vessels, allowing blood to flow more easily. This helps lower blood pressure and reduces the workload on the heart. • Losartan: It helps keep blood vessels relaxed and open, improving blood flow throughout the body. This helps lower blood pressure and supports heart and blood vessel health. • Hydrochlorothiazide: It helps the body remove excess salt and water through urine. This reduces the amount of fluid in the blood vessels, helping to lower blood pressure and improve circulation.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Dipress HL 50mg/5mg/12.5mg Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Dipress HL 50mg/5mg/12.5mg Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Dipress HL 50mg/5mg/12.5mg Tablet is not recommended during breast-feeding. However, your doctor may prescribe it for you during breast-feeding if he/she feels that the benefit to you outweighs the risk. You should not take Dipress HL 50mg/5mg/12.5mg Tablet without a doctor's advice.

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Driving

Caution

It is advised to drive with caution after taking Dipress HL 50mg/5mg/12.5mg Tablet as it usually causes drowsiness and affects the driving ability.

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Liver

Caution

Dipress HL 50mg/5mg/12.5mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Dipress HL 50mg/5mg/12.5mg Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Efficacy and safety of Dipress HL 50mg/5mg/12.5mg Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harms.

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Heart

Safe if prescribed

Dipress HL 50mg/5mg/12.5mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Dipress HL 50mg/5mg/12.5mg Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Dipress HL 50mg/5mg/12.5mg Tablet

Do not take more than the prescribed dose of Dipress HL 50mg/5mg/12.5mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Reduce Sodium Intake: Limit your daily intake of salt and processed foods, as sodium causes your body to hold onto extra fluid, which raises blood pressure.
  • Stay Safely Hydrated: Drink a consistent, moderate amount of water daily. Since this medication contains a water pill, proper hydration is essential, but avoid drinking excessive fluids all at once.
  • Be Mindful of Potassium: Avoid taking potassium supplements or using salt substitutes containing potassium unless specifically instructed by your doctor, as this medication can raise potassium levels in your blood.
  • Stand Up Slowly: To prevent dizziness or fainting, take your time when moving from a sitting or lying position to a standing position.
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How Soon It Starts Working

The time required for Dipress HL 50mg/5mg/12.5mg Tablet to start to work: Dipress HL 50mg/5mg/12.5mg Tablet ideally shows its action within 4 to 8 hours after administration. 

The time for which the effects of Dipress HL 50mg/5mg/12.5mg Tablet last: The effect of Dipress HL 50mg/5mg/12.5mg Tablet lasts for 1 to 2 days.

What if you forget to take Dipress HL 50mg/5mg/12.5mg Tablet

If you miss a dose of Dipress HL 50mg/5mg/12.5mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid potassium-containing salt substitutes: Do not use salt substitutes that contain potassium unless approved by your doctor, as they may increase the risk of high blood potassium levels.
  • Monitor your blood pressure regularly: Check your blood pressure at home as advised and keep a record of your readings to share with your healthcare provider during follow-up visits.
  • Use caution during activities requiring alertness: Dipress HL 50mg/5mg/12.5mg Tablet may cause dizziness or drowsiness, especially when starting treatment. Avoid driving or operating machinery until you know how the medicine affects you.
  • Protect your skin from sunlight: Dipress HL 50mg/5mg/12.5mg Tablet may increase your sensitivity to sunlight. Wear protective clothing and use sunscreen when spending time outdoors to help prevent sunburn.
  • Inform healthcare providers before procedures: Tell your dentist, surgeon, or other healthcare professionals that you are taking Dipress HL 50mg/5mg/12.5mg Tablet before undergoing any medical procedure or starting new medicines.

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Drug-Drug Interactions

  • Potassium Supplements and Potassium-Sparing Water Pills: May increase the risk of developing dangerously high levels of potassium in your blood.
  • Nonsteroidal Anti-inflammatory Drugs (NSAIDs) (e.g., Ibuprofen): Pain relievers l may reduce the blood pressure-lowering effect of Dipress HL 50mg/5mg/12.5mg Tablet and significantly increase the risk of kidney damage.
  • Medicine for bipolar disorder (e.g., Lithium): Taking this medication alongside lithium can cause lithium levels to build up to toxic amounts in your body.

Drug-Food Interactions

  • Alcohol: Drinking alcohol can excessively lower your blood pressure, raising the risk of severe dizziness, fainting, or falls.
  • Grapefruit Juice: May increase the concentration of certain active ingredients of Dipress HL 50mg/5mg/12.5mg Tablet in your system, increasing the risk of side effects.

Drug-Disease Interactions

  • Kidney or Liver Damage: This medication can accumulate in your body or worsen organ function in individuals with pre-existing kidney or liver conditions.
  • Diabetes and Gout: The diuretic component may raise blood sugar levels or trigger a painful gout flare-up in susceptible individuals.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Dipress HL 50mg/5mg/12.5mg Tablet is used in the treatment of high blood pressure (hypertension).
Yes, the use of Dipress HL 50mg/5mg/12.5mg Tablet can make you feel dizzy. This may occur when you suddenly rise up from sitting or lying or position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been lying down or sitting.
In case you have missed a dose of Dipress HL 50mg/5mg/12.5mg Tablet, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both doses together. Take only one dose, taking a double dose of Dipress HL 50mg/5mg/12.5mg Tablet will lead to very low blood pressure.
You may experience fluid loss or dehydration while on Dipress HL 50mg/5mg/12.5mg Tablet. To avoid this condition, it is advisable to drink a lot of fluids as advised by your doctor.
Untreated high blood pressure may add workload to the heart and arteries. If this continues for a long duration of time, the heart and arteries may not function properly and can damage blood vessels of the brain, heart, and kidneys, resulting in a stroke, kidney failure, or heart failure. So, taking prescribed blood pressure medication, along with diet and exercise can reduce the risk of strokes and heart attacks.
No, you are advised to inform your doctor before stopping this medicine. Depending upon your current blood pressure readings, there is a possibility that your doctor may lower your dose, but not recommend you to discontinue or stop the medicine.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
Dipress HL 50mg/5mg/12.5mg Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions and one should not abruptly discontinue it without discussing it with a doctor.
No, you must not take Dipress HL 50mg/5mg/12.5mg Tablet if you are pregnant. The medication contains active ingredients that can cause severe injury or death to an unborn baby, particularly during the second and third trimesters. If you suspect you are pregnant, stop taking the medicine immediately and talk to your doctor.
This medication contains a diuretic, or water pill, which helps your kidneys remove extra salt and water from your body. This naturally leads to more frequent urination, especially when you first start the treatment. To avoid waking up in the night, take your dose in the morning. Talk to your doctor if this becomes unmanageable.
Yes, your doctor will likely request routine blood tests to check your kidney function and monitor your blood electrolyte levels, such as potassium and sodium. These tests ensure the medication is working safely. Talk to your doctor to schedule these checks.
No, you should avoid salt substitutes containing potassium. Dipress HL 50mg/5mg/12.5mg Tablet can naturally increase potassium levels in your blood, and adding more potassium through your diet can lead to a dangerous condition called hyperkalemia, which affects heart rhythm. Talk to your doctor before changing your diet.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Mayo Clinic Staff. Syc 20373410 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Mayo Clinic Staff. Drg 20061784 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Hydrochlorothiazide Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Losartan Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Amlodipine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Amlodipine besylate [Prescribing Information]. 2011. [Accessed on 11 Apr. 2019]Check here
  7. Hydrochlorothiazide [Prescribing Information]. 2011. [Accessed on 11 Apr. 2019]Check here

Country of origin

India
Other Info - DI80743
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