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Divagrace 250 Tab is used to treat seizures and manage manic episodes in bipolar disorder. It also helps prevent migraine attacks. It supports better brain stability and reduces symptom frequency. This helps improve daily functioning and overall quality of life.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VALPROIC ACID-250MG

Manufacturer/Marketer :

Cyrus Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Divagrace 250 Tab

Divagrace 250 Tab is used to treat epilepsy/seizures/fits. In addition, Divagrace 250 Tab also treats manic episodes associated with bipolar disorder. Additionally, it can prevent migraine symptoms (such as headache).

Divagrace 250 Tab contains valproic acid, which helps stabilise abnormal brain activity. It supports effective seizure control and helps calm overactive neural activity. It also helps manage mood changes in bipolar disorder and reduces the frequency of migraine attacks. This improves neurological balance and supports better functioning.

Administer Divagrace 250 Tab with food to prevent gastrointestinal upset. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any components present in Divagrace 250 Tab . If you are pregnant, do not take Divagrace 250 Tab because it may cause serious congenital defects. Divagrace 250 Tab is generally not recommended during breastfeeding; consult your physician before taking Divagrace 250 Tab .

Uses of Divagrace 250 Tab

Divagrace 250 Tab is used for the treatment of epilepsy (seizures), bipolar disorder, and migraine. The detailed uses of Divagrace 250 Tab are as follows:

  • Controls Seizures: Divagrace 250 Tab helps prevent and control seizures by calming overactive neural activity.
  • Manages Bipolar Disorder: Divagrace 250 Tab helps to control manic episodes and stabilise mood in individuals with bipolar disorder.
  • Prevents Migraine Headaches: Divagrace 250 Tab is also prescribed as a preventive treatment to reduce the frequency and severity of migraine attacks.

Key Benefits

Divagrace 250 Tab , when used as prescribed, may provide the following benefits:

For Controls Seizures:

  • Helps stabilise abnormal electrical activity in the brain.
  • Reduces sudden episodes of excessive brain stimulation

For Managing Bipolar Disorder:

  • Helps maintain emotional balance.
  • Reduces the intensity and frequency of extreme mood changes

For Preventing Migraine Headaches:

  • Helps reduce the risk of recurrent severe headaches.
  • Reduces the impact of migraine on daily life.

Directions for Use

  • Divagrace 250 Tab can be taken with food to avoid stomach upset.
  • It is usually taken twice daily; however, your doctor may adjust the dosage and timing based on your medical condition and response to treatment.
  • Swallow Divagrace 250 Tab as a whole with a glass of water.
  • Do not crush or chew this medication.

How Divagrace 250 Tab Works

Divagrace 250 Tab contains valproic acid, which helps calm excessive nerve activity in the brain. As a result, it aids in controlling seizures. In bipolar disorder, Divagrace 250 Tab raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. In migraine, Divagrace 250 Tab limits the transmission of pain, thereby preventing migraine.
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Alcohol

Unsafe

Do not consume alcohol while taking Divagrace 250 Tab as alcohol can worsen the side effects of the Divagrace 250 Tab , including sleepiness and dizziness.

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Pregnancy

Unsafe

Divagrace 250 Tab is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with Divagrace 250 Tab .

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Breast Feeding

Caution

Divagrace 250 Tab passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking Divagrace 250 Tab . Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Unsafe

Divagrace 250 Tab may cause dizziness, drowsiness, or fatigue in some individuals. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking Divagrace 250 Tab .

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Liver

Caution

Inform your doctor before taking the Divagrace 250 Tab if you have a history of liver diseases. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing Divagrace 250 Tab .

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Caution

Use is not recommended for children under 10 years old. Your doctor will decide the dose based on your child's condition if they are more than ten years old.

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Heart

Caution

Divagrace 250 Tab can be used cautiously in patients with heart disease if prescribed by a physician.

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Geriatrics

Caution

Divagrace 250 Tab can be given to elderly patients with extreme caution if prescribed by a physician.

What if I have taken an overdose of Divagrace 250 Tab

Avoid exceeding the prescribed dose, as this may lead to adverse effects. Symptoms of adverse effects may include sleepiness, an irregular heartbeat, and coma (loss of consciousness). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Diet:

  • Follow a high-fat, low-carbohydrate diet if advised by your doctor.
  • Maintain a balanced meal plan to support overall health.

Physical Activity:

  • Exercise regularly to help maintain a healthy weight and general fitness.

Safety & Preparedness:

  • Keep a seizure response plan and inform people around you.
  • Make simple home safety changes to reduce injury risk.
  • Identify and avoid known seizure triggers.
  • Use an alarm or emergency device to call for help during a seizure.

Rest & Sleep:

  • Get enough rest and sleep to reduce seizure risk.

Habits:

  • Avoid smoking and alcohol consumption.

Stress Management:

  • Practice meditation or yoga to reduce stress and improve coping ability.

Have a query?

How Soon It Starts Working

  • The time required for Divagrace 250 Tab to start to work: Divagrace 250 Tab ideally shows its action within 1 to 4 hours after administration.
  • The time for which the effects of Divagrace 250 Tab last: The effect of Divagrace 250 Tab lasts for 13 to 19 hours.

What if you forget to take Divagrace 250 Tab

If you forget to take a dose of Divagrace 250 Tab , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dose. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Divagrace 250 Tab out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Before taking the Divagrace 250 Tab , let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
  • Inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding.
  • You should not become pregnant during treatment with Divagrace 250 Tab .
  • Consult your doctor immediately if you become pregnant while taking Divagrace 250 Tab .
  • Alcohol should be avoided during treatment with this medicine.
  • You must not drive or operate machinery while taking Divagrace 250 Tab .

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Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

  • Immunity-lowering medicines (Leflunomide, Teriflunomide)
    Potential effect: May increase the risk of liver problems when used together.
  • Anaesthetic (loss of sensation) and pain-relief medicine (Ketamine)
    Potential effect: May increase side effects and cause respiratory depression.
  • Mood-stabilising medicine (Lithium)
    Potential effect: May increase the risk of irregular heart rhythm.
  • Strong pain-relief medicine – Opioid (Buprenorphine)
    Potential effect: May increase the risk of severe side effects, including breathing problems and loss of consciousness.
  • Antibiotic medicines (Ertapenem, Meropenem)
    Potential effect: May reduce the blood levels of Divagrace 250 Tab and decrease its effectiveness.

Drug-Food Interactions:

  • Alcohol: Avoid alcohol while taking Divagrace 250 Tab , as it may increase dizziness and sleepiness.

Drug-Disease Interactions: Inform your doctor if you have a history of this condition before taking Divagrace 250 Tab .

  • Depression
  • Liver disease
  • Urea cycle disorders (ammonia buildup disorders)
  • Suicidal thoughts
  • HIV disease
  • Hereditary mitochondrial disorders
  • Thrombocytopenia (low platelets)

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Divagrace 250 Tab is used to treat epilepsy/seizures/fits. In addition, it also helps treat manic episodes associated with bipolar disorder and prevent migraine symptoms (like a headache).

Divagrace 250 Tab decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Divagrace 250 Tab helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Divagrace 250 Tab limits the transmission of nerve pain, thereby preventing migraine headaches. Migraines are a neurological condition characterised by intense headaches.

Divagrace 250 Tab may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Divagrace 250 Tab . Avoid getting pregnant while taking Divagrace 250 Tab as it could lead to serious birth defects. Do not stop taking Divagrace 250 Tab and consult your doctor immediately if you become pregnant.

Divagrace 250 Tab may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Divagrace 250 Tab may cause common side effects such as nausea, vomiting, headache, sleepiness, tremor, weakness, dizziness, stomach pain, and weight gain. If these side effects persist or worsen, please consult your doctor.

Divagrace 250 Tab contains Valproic acid as its active ingredient.

Take Divagrace 250 Tab with food to avoid stomach upset or as advised by your doctor.

You are recommended to avoid alcohol consumption while taking Divagrace 250 Tab as it may worsen the side effects of the Divagrace 250 Tab , including sleepiness and dizziness.

No, Divagrace 250 Tab does not cause addiction. However, Divagrace 250 Tab should be used as per the dose and duration prescribed by your doctor. Do not self-medicate.

Divagrace 250 Tab does not cure epilepsy; it only helps prevent seizures. However, you must take Divagrace 250 Tab for as long as your doctor advises. If you face any difficulty while taking Divagrace 250 Tab , consult your doctor.

If you stop taking Divagrace 250 Tab suddenly, it may increase the risk of recurrence of seizures. Therefore, it should be stopped gradually. If you feel the need to discontinue Divagrace 250 Tab , please consult your physician.

Some birth control pills (oestrogen-containing birth control pills) may lower the levels of Divagrace 250 Tab in blood. Thus, inform your doctor if you are using birth control pills and discuss with your doctor about a suitable method of contraception.

Divagrace 250 Tab is safe for long-term use in many patients when prescribed by a physician. In rare cases, prolonged use of Divagrace 250 Tab may weaken bones, thereby increasing the risk of fractures (osteopenia and osteoporosis). Get regular checkups for bone health if you have been taking Divagrace 250 Tab for a long time.

Divagrace 250 Tab may cause hair thinning, hair colour changes and even hair loss. If you have any concerns about this, please ask your doctor whether it is possible to reduce the dose of Divagrace 250 Tab . Your hair may regrow after either lowering your dose or changing medication.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - DIV0298
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