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DIXIN 0.25MG INJECTION 2ML is an antiarrhythmic medicine used in the treatment of heart failure and irregular heartbeats. It mainly acts on heart muscles. This medication contains digoxin which strengthens the heart muscle's contractions with each heartbeat and thereby increases the heart's efficiency in pumping blood throughout the body. Common side effects include diarrhoea, nausea, dizziness, weakness, headache, etc.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About DIXIN 0.25MG INJECTION 2ML

DIXIN 0.25MG INJECTION 2ML is a prescription medicine injected into the body to treat heart failure and certain types of irregular heartbeats, such as atrial fibrillation. It helps the heart pump blood more efficiently and regulates its rhythm when it beats too fast or unevenly. This medicine is vital for managing chronic heart conditions and preventing sudden worsening of symptoms.

Because this medicine is given as an injection, it is typically scheduled and injected by a healthcare professional in a clinic or hospital setting. Consistency is key, and your healthcare provider will ensure you receive your doses at precise times to keep steady levels of the medicine in your blood. Along with your medical treatment, following a low-salt diet and staying active within safe limits can greatly support your heart health.

While taking DIXIN 0.25MG INJECTION 2ML, you may experience some common side effects like mild nausea, headache, or dizziness. However, you must contact your doctor immediately if you experience severe symptoms like changes in your vision, such as seeing yellow-green halos, or an unusually slow heart rate. These can be warning signs that the level of medicine in your body is too high.

Do not take this if you have specific serious heart rhythm problems, such as ventricular fibrillation. Before starting your treatment, tell your doctor if you have kidney disease, thyroid problems, or low levels of potassium or magnesium in your blood. Your doctor will need to adjust your treatment plan to ensure this medicine is safe for you.

This medicine can interact with several other drugs, including certain water pills and blood pressure medications, which can change how it behaves in your body. It is also important to talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as older individuals are often more sensitive to the effects of DIXIN 0.25MG INJECTION 2ML.
 

Uses of DIXIN 0.25MG INJECTION 2ML

DIXIN 0.25MG INJECTION 2ML is used to treat heart failure and certain types of irregular heartbeats. The detailed uses of DIXIN 0.25MG INJECTION 2ML are as follows:

  • Heart failure: DIXIN 0.25MG INJECTION 2ML helps strengthen the contractions of the heart muscle, allowing it to pump blood more effectively to the rest of your body and reduce fluid buildup.
  • Atrial fibrillation: This medicine slows down the electrical signals in a racing heart, helping to control a rapid or irregular heart rate.
     

Key Benefits

DIXIN 0.25MG INJECTION 2ML helps improve heart function and maintain a steady heart rhythm, reducing symptoms associated with heart conditions. With regular use as prescribed, it helps improve daily physical activity, reduce discomfort, and support long-term cardiovascular health.

  • Improves Heart Function: By helping the heart pump more efficiently, this medicine helps reduce symptoms such as shortness of breath, fatigue, and swelling in the legs or ankles, making everyday activities easier to perform.
  • Helps Maintain a Steady Heart Rhythm: This medicine helps control irregular or rapid heartbeats, reducing sensations of a racing or fluttering heart and promoting a more stable heartbeat.
  • Supports Better Quality of Life: By improving heart performance and controlling heart rhythm, this medicine helps increase exercise tolerance, improve physical comfort, and support overall cardiovascular well-being.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • DIXIN 0.25MG INJECTION 2ML will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How DIXIN 0.25MG INJECTION 2ML Works

DIXIN 0.25MG INJECTION 2ML contains digoxin, which works by targeting the microscopic pumps within your heart muscle cells. It blocks a specific enzyme called the sodium-potassium pump. By slowing down this pump, the medicine causes more calcium to build up inside the heart muscle cells. Since calcium is essential for muscle contraction, this extra calcium allows the heart to squeeze with more force, improving its pumping power. At the same time, DIXIN 0.25MG INJECTION 2ML acts on the nervous system to slow down the electrical signals travelling through the heart. This action calms the upper chambers of the heart, preventing them from beating too rapidly and helping the heart maintain a steadier, safer rhythm.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with DIXIN 0.25MG INJECTION 2ML as it may increase drowsiness and reduce the amount of DIXIN 0.25MG INJECTION 2ML in the blood leading to abnormal heart function.

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Pregnancy

Caution

DIXIN 0.25MG INJECTION 2ML is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. DIXIN 0.25MG INJECTION 2ML is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

DIXIN 0.25MG INJECTION 2ML may cause dizziness, yellow or blurred vision in some people. So, drive only if you are alert after taking DIXIN 0.25MG INJECTION 2ML.

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Liver

Caution

If you have any concerns regarding the use of DIXIN 0.25MG INJECTION 2ML in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take DIXIN 0.25MG INJECTION 2ML with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Please consult the doctor. The doctor will recommend a specific dose for children based on their age.

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Heart

Caution

DIXIN 0.25MG INJECTION 2ML should be administered with caution in patients with heart problems. Please talk to your doctor before receiving DIXIN 0.25MG INJECTION 2ML.

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Geriatrics

Caution

DIXIN 0.25MG INJECTION 2ML should be administered with caution in elderly patients due to an increased risk of side effects.

What if I have taken an overdose of DIXIN 0.25MG INJECTION 2ML

If you suspect an overdose, seek emergency medical care. Symptoms of an overdose can be serious and include severe vomiting, extreme dizziness, vision changes, confusion, and a dangerously irregular heartbeat.

Diet & Lifestyle Advise

  • Monitor your potassium intake: Eat potassium-rich foods, such as bananas, oranges, and leafy green vegetables, as directed by your doctor. Low potassium levels in your blood can increase the risk of side effects from DIXIN 0.25MG INJECTION 2ML.
  • Limit your salt: Reduce the amount of sodium in your diet to help prevent fluid retention and ease the workload on your heart.
  • Track your weight daily: Weigh yourself every morning before breakfast. Tell your doctor immediately if you notice a sudden weight gain of 2 to 3 pounds in a single day, as this can be a sign of worsening heart failure.
  • Avoid excess alcohol: Limit or avoid alcohol, as it can weaken your heart muscle and worsen heart rhythm problems.
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How Soon It Starts Working

The time required for DIXIN 0.25MG INJECTION 2ML to start to work: DIXIN 0.25MG INJECTION 2ML effect can be observed within 5 to 30 minutes of IV administration. The time for which the effects of DIXIN 0.25MG INJECTION 2ML last: DIXIN 0.25MG INJECTION 2ML effect last for 3 to 4 days.

What if you forget to take DIXIN 0.25MG INJECTION 2ML

Because this medicine is usually given by a healthcare professional, missed doses are rare. However, if you are receiving this treatment at home and miss a scheduled injection, contact your healthcare provider immediately for instructions. Do not inject a double dose to make up for a missed one.

Storage

• Store DIXIN 0.25MG INJECTION 2ML vials at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the injection vial before use. Do not inject the liquid if it is discoloured, cloudy, or contains visible floating particles.
  • Check your pulse daily. Ask your doctor what your target heart rate should be, and contact them immediately if your pulse drops below that number (usually 60 beats per minute).
  • Ensure you attend all scheduled appointments for blood tests, as your doctor needs to check your kidney health and the level of DIXIN 0.25MG INJECTION 2ML in your system to prevent toxicity.
  • If you inject this medicine at home, safely dispose of all needles and syringes in an approved sharps container immediately after use.
  • Do not switch to a different brand or form of this medicine without your doctor’s knowledge, as different products may not work the same way in your body.

Drug-Drug Interactions

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  • Water pills (diuretics): Some water pills can lower your potassium and magnesium levels, which increases your risk of developing serious side effects from DIXIN 0.25MG INJECTION 2ML.
  • Calcium channel blockers and beta-blockers: Taking these heart medicines alongside DIXIN 0.25MG INJECTION 2ML can cause your heart rate to slow down to a dangerous level.
  • Amiodarone and quinidine: These heart rhythm medicines can significantly increase the level of DIXIN 0.25MG INJECTION 2ML in your blood, requiring a reduction in your dose.
     

Drug-Drug Interactions

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How does the drug interact with Dixin 0.25mg Injection 2ml:
Coadministration of Dixin 0.25mg Injection 2ml and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25mg Injection 2ml and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Amiodarone with Dixin 0.25mg Injection 2ml can increase Dixin 0.25mg Injection 2ml levels which can lead to severe side effects.

How to manage the interaction:
Taking Amiodarone with Dixin 0.25mg Injection 2ml together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, visual disturbances, slow pulse, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml with Telaprevir may increase the blood levels and effects of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
Although taking Telaprevir and Dixin 0.25mg Injection 2ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Dixin 0.25mg Injection 2ml levels. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Calcium carbonate and Dixin 0.25mg Injection 2ml may increase the calcium levels may increase the effects of Dixin 0.25mg Injection 2ml

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Dixin 0.25mg Injection 2ml if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Glycopyrronium bromide may increase the serum concentration of Dixin 0.25mg Injection 2ml and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25mg Injection 2ml and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Adenosine with Dixin 0.25mg Injection 2ml shows additive effects on the heart and may cause abnormal heart rhythms.

How to manage the interaction:
Taking Adenosine with Dixin 0.25mg Injection 2ml together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
DigoxinSaquinavir
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Famotidine may increase the level or effect of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25mg Injection 2ml and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Ceritinib may slow down the heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Dixin 0.25mg Injection 2ml and ceritinib, it can be taken together if prescribed by a doctor. However, if you experience fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No clinically significant food interactions are known with DIXIN 0.25MG INJECTION 2ML when used as directed.

DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin 0.25mg Injection 2ml with Grapefruit and Grapefruit juice may increase the side effects of Dixin 0.25mg Injection 2ml. Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin 0.25mg Injection 2ml.

Habit Forming

No

Therapeutic Class

[ANTIARRHYTHMICS]

FAQs

DIXIN 0.25MG INJECTION 2ML is used to treat heart failure and irregular heartbeats.
DIXIN 0.25MG INJECTION 2ML increases the force with which heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal.
DIXIN 0.25MG INJECTION 2ML may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.
You are recommended to avoid taking DIXIN 0.25MG INJECTION 2ML if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).
You are not recommended to take amiodarone with DIXIN 0.25MG INJECTION 2ML as co-administration of these two medicines may increase the levels of digoxin in the blood resulting in digoxin toxicity. However, please consult a doctor before taking other medicines with DIXIN 0.25MG INJECTION 2ML so that the dose may be adjusted appropriately.
You are not recommended to take more than the prescribed dose of DIXIN 0.25MG INJECTION 2ML as it may cause DIXIN 0.25MG INJECTION 2ML toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances. However, if you experience any of these symptoms while taking DIXIN 0.25MG INJECTION 2ML, please consult a doctor immediately.
Yes, DIXIN 0.25MG INJECTION 2ML may cause diarrhoea as a side effect. However, it is not necessary for everyone taking DIXIN 0.25MG INJECTION 2ML to experience this side effect. You are recommended to drink plenty of fluids in order to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsens, please consult your doctor.
DIXIN 0.25MG INJECTION 2ML is typically injected slowly into a vein (intravenously) or deep into a muscle (intramuscularly) by a healthcare provider in a clinical setting. Talk to your doctor if you have questions about how your therapy is given.
Signs of a high dose include severe nausea, vomiting, loss of appetite, confusion, extreme tiredness, and visual disturbances like seeing yellow-green halos. If you notice these, talk to your doctor immediately.
Yes, but because the kidneys clear this medicine from your body, your doctor will need to monitor your kidney function closely and will likely prescribe a gradually increasing dose or a lower overall dose. Talk to your doctor about your kidney health.
Blood tests are necessary to measure the exact amount of the medicine in your blood, as the line between a helpful dose and a toxic dose is very narrow. Your doctor will also check your kidney function and mineral levels. Talk to your doctor to learn more.
Blurry vision or seeing unusual colours is a serious warning sign of medicine buildup. Stop receiving the medicine and contact your healthcare provider or seek emergency care immediately. Talk to your doctor right away.
DIXIN 0.25MG INJECTION 2ML should only be used during pregnancy if your doctor determines the benefits outweigh the risks to your baby. Your doctor will need to monitor your blood levels closely. Talk to your doctor if you are pregnant or planning to become pregnant.
Yes, one of the effects of this medicine is to slow down a fast heart rate. If your pulse drops too low (usually below 60 beats per minute) or if you feel dizzy or faint, talk to your doctor immediately.
You should only take potassium supplements if they are specifically prescribed by your doctor. Both high and low potassium levels can be dangerous when using this medicine. Talk to your doctor before taking any supplements.

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Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0002
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