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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
DIXIN 0.25MG INJECTION 2ML is an antiarrhythmic medicine used in the treatment of heart failure and irregular heartbeats. It mainly acts on heart muscles. This medication contains digoxin which strengthens the heart muscle's contractions with each heartbeat and thereby increases the heart's efficiency in pumping blood throughout the body. Common side effects include diarrhoea, nausea, dizziness, weakness, headache, etc.
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Composition :

DIGOXIN-0.25MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About DIXIN 0.25MG INJECTION 2ML

DIXIN 0.25MG INJECTION 2ML is used to treat heart failure and irregular heartbeats. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which the heart beats irregularly, i.e., too fast, or too slow. 

DIXIN 0.25MG INJECTION 2ML contains Digoxin, which works on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

DIXIN 0.25MG INJECTION 2ML will be administered by a healthcare professional; do not self-administer. Some people may experience diarrhoea, nausea, dizziness, weakness, headache, or anxiety. Most of these side effects of DIXIN 0.25MG INJECTION 2ML do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. 

If you are known to be allergic to Digoxin or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking DIXIN 0.25MG INJECTION 2ML. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food), or any lung or kidney disease, please inform your doctor before taking DIXIN 0.25MG INJECTION 2ML so that the dose may be adjusted or an alternate medicine may be prescribed accordingly.

Uses of DIXIN 0.25MG INJECTION 2ML

Prevention of heart failure and Irregular heartbeats

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• DIXIN 0.25MG INJECTION 2ML will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

DIXIN 0.25MG INJECTION 2ML is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. DIXIN 0.25MG INJECTION 2ML increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal. DIXIN 0.25MG INJECTION 2ML improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

How DIXIN 0.25MG INJECTION 2ML Works

DIXIN 0.25MG INJECTION 2ML contains Digoxin, which works on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Storage

• Store in a cool and dry place away from sunlight.• Keep DIXIN 0.25MG INJECTION 2ML out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of DIXIN 0.25MG INJECTION 2ML

A healthcare professional administers DIXIN 0.25MG INJECTION 2ML in a hospital setting. Hence, the chances of overdose are less. Overdose may cause confusion, loss of appetite, nausea, vomiting, diarrhea, or vision problems. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

If you are known to be allergic to DIXIN 0.25MG INJECTION 2ML or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking DIXIN 0.25MG INJECTION 2ML. Avoid intake of alcohol with DIXIN 0.25MG INJECTION 2ML as it may increase the risk of drowsiness. DIXIN 0.25MG INJECTION 2ML may cause vision problems in some people; drive or operate machinery only if you are alert. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking DIXIN 0.25MG INJECTION 2ML so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. DIXIN 0.25MG INJECTION 2ML has a narrow therapeutic index which makes its use limited and requires close monitoring as a small change in dose or blood concentration may lead to severe adverse effects and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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DigoxinSaquinavir
Severe

Drug-Drug Interactions

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DigoxinSaquinavir
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Sucralfate together with Dixin 0.25mg Injection 2ml may decrease the effects of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Famotidine may increase the level or effect of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25mg Injection 2ml and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Glycopyrronium bromide may increase the serum concentration of Dixin 0.25mg Injection 2ml and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.25mg Injection 2ml and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Adenosine with Dixin 0.25mg Injection 2ml shows additive effects on the heart and may cause abnormal heart rhythms.

How to manage the interaction:
Taking Adenosine with Dixin 0.25mg Injection 2ml together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinBretylium tosilate
Severe
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Bretylium tosilate may increase the effect of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
Although taking Bretylium tosilate and Dixin 0.25mg Injection 2ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling sick, throwing up, having seizures, feeling tired, or noticing your heart beating too fast or too slow, it's best to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Amiodarone with Dixin 0.25mg Injection 2ml can increase Dixin 0.25mg Injection 2ml levels which can lead to severe side effects.

How to manage the interaction:
Taking Amiodarone with Dixin 0.25mg Injection 2ml together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, visual disturbances, slow pulse, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Ceritinib may slow down the heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Dixin 0.25mg Injection 2ml and ceritinib, it can be taken together if prescribed by a doctor. However, if you experience fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.25mg Injection 2ml:
Co-administration of Dixin 0.25mg Injection 2ml and Lapatinib may increase the blood levels and effects of Dixin 0.25mg Injection 2ml.

How to manage the interaction:
If you are supposed to take Dixin 0.25mg Injection 2ml and Lapatinib together, a doctor may adjust the dose or monitor more frequently to safely use both medications. If you experience diarrhea, nausea, loss of appetite, vomiting, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, contact a doctor as these may be signs and symptoms of excessive Dixin 0.25mg Injection 2ml levels. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.25MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin 0.25mg Injection 2ml with Grapefruit and Grapefruit juice may increase the side effects of Dixin 0.25mg Injection 2ml. Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin 0.25mg Injection 2ml.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

  • Regular exercise is advised as it helps to lower blood pressure and keeps blood vessels and the heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat a balanced and healthy diet which includes plenty of vegetables, fruits, and low-fat or fat-free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with DIXIN 0.25MG INJECTION 2ML as it may increase drowsiness and reduce the amount of DIXIN 0.25MG INJECTION 2ML in the blood leading to abnormal heart function.

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Pregnancy

Caution

DIXIN 0.25MG INJECTION 2ML is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. DIXIN 0.25MG INJECTION 2ML is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

DIXIN 0.25MG INJECTION 2ML may cause dizziness, yellow or blurred vision in some people. So, drive only if you are alert after taking DIXIN 0.25MG INJECTION 2ML.

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Liver

Caution

If you have any concerns regarding the use of DIXIN 0.25MG INJECTION 2ML in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take DIXIN 0.25MG INJECTION 2ML with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Please consult the doctor. The doctor will recommend a specific dose for children based on their age.

Have a query?

FAQs

DIXIN 0.25MG INJECTION 2ML is used to treat heart failure and irregular heartbeats.

DIXIN 0.25MG INJECTION 2ML increases the force with which heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal.

DIXIN 0.25MG INJECTION 2ML may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.

You are recommended to avoid taking DIXIN 0.25MG INJECTION 2ML if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).

You are not recommended to take amiodarone with DIXIN 0.25MG INJECTION 2ML as co-administration of these two medicines may increase the levels of digoxin in the blood resulting in digoxin toxicity. However, please consult a doctor before taking other medicines with DIXIN 0.25MG INJECTION 2ML so that the dose may be adjusted appropriately.

You are not recommended to take more than the prescribed dose of DIXIN 0.25MG INJECTION 2ML as it may cause DIXIN 0.25MG INJECTION 2ML toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances. However, if you experience any of these symptoms while taking DIXIN 0.25MG INJECTION 2ML, please consult a doctor immediately.

Yes, DIXIN 0.25MG INJECTION 2ML may cause diarrhoea as a side effect. However, it is not necessary for everyone taking DIXIN 0.25MG INJECTION 2ML to experience this side effect. You are recommended to drink plenty of fluids in order to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsens, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0002

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