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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dixin 0.5 mg Injection 10 x 2 ml is an antiarrhythmic medicine used in the treatment of heart failure and irregular heartbeats. It mainly acts on heart muscles. This medication contains digoxin which strengthens the heart muscle's contractions with each heartbeat and thereby increases the heart's efficiency in pumping blood throughout the body. Common side effects include diarrhoea, nausea, dizziness, weakness, headache, etc.
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Composition :

DIGOXIN-0.5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dixin 0.5 mg Injection 10 x 2 ml

Dixin 0.5 mg Injection 10 x 2 ml is used to treat heart failure and irregular heartbeats. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which the heart beats irregularly, i.e., too fast, or too slow. 

Dixin 0.5 mg Injection 10 x 2 ml contains Digoxin, which works on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Dixin 0.5 mg Injection 10 x 2 ml will be administered by a healthcare professional; do not self-administer. Some people may experience diarrhoea, nausea, dizziness, weakness, headache, or anxiety. Most of these side effects of Dixin 0.5 mg Injection 10 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. 

If you are known to be allergic to Digoxin or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking Dixin 0.5 mg Injection 10 x 2 ml . If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (inability to absorb minerals from food), or any lung or kidney disease, please inform your doctor before taking Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly.

Uses of Dixin 0.5 mg Injection 10 x 2 ml

Prevention of heart failure and Irregular heartbeats

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Dixin 0.5 mg Injection 10 x 2 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Dixin 0.5 mg Injection 10 x 2 ml is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Dixin 0.5 mg Injection 10 x 2 ml increases the force with which the heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal. Dixin 0.5 mg Injection 10 x 2 ml improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

How Dixin 0.5 mg Injection 10 x 2 ml Works

Dixin 0.5 mg Injection 10 x 2 ml contains Digoxin, which works on the heart muscle and increases the force with which the heart muscle contracts with each heartbeat. Thereby, it makes the heart efficient in pumping blood around the body and slows down the rate at which the heart beats.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dixin 0.5 mg Injection 10 x 2 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dixin 0.5 mg Injection 10 x 2 ml

A healthcare professional administers Dixin 0.5 mg Injection 10 x 2 ml in a hospital setting. Hence, the chances of overdose are less. Overdose may cause confusion, loss of appetite, nausea, vomiting, diarrhea, or vision problems. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

If you are known to be allergic to Dixin 0.5 mg Injection 10 x 2 ml or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking Dixin 0.5 mg Injection 10 x 2 ml . Avoid intake of alcohol with Dixin 0.5 mg Injection 10 x 2 ml as it may increase the risk of drowsiness. Dixin 0.5 mg Injection 10 x 2 ml may cause vision problems in some people; drive or operate machinery only if you are alert. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin 0.5 mg Injection 10 x 2 ml has a narrow therapeutic index which makes its use limited and requires close monitoring as a small change in dose or blood concentration may lead to severe adverse effects and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Sucralfate together with Dixin 0.5 mg Injection 10 x 2 ml may decrease the effects of Dixin 0.5 mg Injection 10 x 2 ml .

How to manage the interaction:
If you are supposed to take Dixin 0.5 mg Injection 10 x 2 ml and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Calcium gluconate with Dixin 0.5 mg Injection 10 x 2 ml may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Dixin 0.5 mg Injection 10 x 2 ml if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
DigoxinTelaprevir
Severe
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml with Telaprevir may increase the blood levels and effects of Dixin 0.5 mg Injection 10 x 2 ml .

How to manage the interaction:
Although taking Telaprevir and Dixin 0.5 mg Injection 10 x 2 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat, as these may be signs and symptoms of excessive Dixin 0.5 mg Injection 10 x 2 ml levels. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml and Famotidine may increase the level or effect of Dixin 0.5 mg Injection 10 x 2 ml .

How to manage the interaction:
Although there is a possible interaction between Dixin 0.5 mg Injection 10 x 2 ml and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Fingolimod with Dixin 0.5 mg Injection 10 x 2 ml may increase the risk or severity of slowing down of the heart rate.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.5 mg Injection 10 x 2 ml and Fingolimod, you can take these medicines together if prescribed by a doctor. It's important to monitor your heart rate and talk to a doctor about any alternative medications that don't interact. If you experience any symptoms like chest pain, shortness of breath, or fainting, it's important to call your doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Coadministration of Dixin 0.5 mg Injection 10 x 2 ml and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.5 mg Injection 10 x 2 ml and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Adenosine with Dixin 0.5 mg Injection 10 x 2 ml shows additive effects on the heart and may cause abnormal heart rhythms.

How to manage the interaction:
Taking Adenosine with Dixin 0.5 mg Injection 10 x 2 ml together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
DigoxinDolasetron
Severe
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml with Dolasetron can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml with Dolasetron can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these risk factors or if you experience symptoms like an irregular heartbeat, dizziness, fainting, or a fast or irregular heartbeat, it is important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Dixin 0.5 mg Injection 10 x 2 ml and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Dixin 0.5 mg Injection 10 x 2 ml :
Co-administration of Dixin 0.5 mg Injection 10 x 2 ml and Glycopyrronium bromide may increase the serum concentration of Dixin 0.5 mg Injection 10 x 2 ml and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dixin 0.5 mg Injection 10 x 2 ml and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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DIGOXIN-0.5MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-0.5MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin 0.5 mg Injection 10 x 2 ml with Grapefruit and Grapefruit juice may increase the side effects of Dixin 0.5 mg Injection 10 x 2 ml . Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin 0.5 mg Injection 10 x 2 ml .

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.

  • Regular exercise is advised as it helps to lower blood pressure and keeps blood vessels and the heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat a balanced and healthy diet which includes plenty of vegetables, fruits, and low-fat or fat-free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Dixin 0.5 mg Injection 10 x 2 ml as it may increase drowsiness and reduce the amount of Dixin 0.5 mg Injection 10 x 2 ml in the blood leading to abnormal heart function.

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Pregnancy

Caution

Dixin 0.5 mg Injection 10 x 2 ml is a Category C pregnancy drug and is to be given to pregnant women only if it is clearly needed and prescribed by a doctor.

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Breast Feeding

Caution

Please consult a doctor if you are breastfeeding. Dixin 0.5 mg Injection 10 x 2 ml is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Dixin 0.5 mg Injection 10 x 2 ml may cause dizziness, yellow or blurred vision in some people. So, drive only if you are alert after taking Dixin 0.5 mg Injection 10 x 2 ml .

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Liver

Caution

If you have any concerns regarding the use of Dixin 0.5 mg Injection 10 x 2 ml in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take Dixin 0.5 mg Injection 10 x 2 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Please consult the doctor. The doctor will recommend a specific dose for children based on their age.

Have a query?

FAQs

Dixin 0.5 mg Injection 10 x 2 ml is used to treat heart failure and irregular heartbeats.

Dixin 0.5 mg Injection 10 x 2 ml increases the force with which heart muscle contracts with each heartbeat and makes the heart efficient in pumping blood around the body. Thus, slows down the rate at which the heart beats and makes the heart rate normal.

Dixin 0.5 mg Injection 10 x 2 ml may cause yellow or blurred vision in some people. Therefore, be cautious before driving or using machinery.

You are recommended to avoid taking Dixin 0.5 mg Injection 10 x 2 ml if you have severe heart problems, have a history of Stokes-Adams attacks (abrupt, short-lived unconsciousness caused by a sudden change in a heartbeat), obstructive cardiomyopathy (enlargement of the heart muscle) and Wolff-Parkinson-White syndrome (extra electrical pathway causes fast heartbeat).

You are not recommended to take amiodarone with Dixin 0.5 mg Injection 10 x 2 ml as co-administration of these two medicines may increase the levels of digoxin in the blood resulting in digoxin toxicity. However, please consult a doctor before taking other medicines with Dixin 0.5 mg Injection 10 x 2 ml so that the dose may be adjusted appropriately.

You are not recommended to take more than the prescribed dose of Dixin 0.5 mg Injection 10 x 2 ml as it may cause Dixin 0.5 mg Injection 10 x 2 ml toxicity resulting in symptoms such as vomiting, nausea, loss of appetite, tiredness, dizziness or visual disturbances. However, if you experience any of these symptoms while taking Dixin 0.5 mg Injection 10 x 2 ml , please consult a doctor immediately.

Yes, Dixin 0.5 mg Injection 10 x 2 ml may cause diarrhoea as a side effect. However, it is not necessary for everyone taking Dixin 0.5 mg Injection 10 x 2 ml to experience this side effect. You are recommended to drink plenty of fluids in order to avoid dehydration. Signs of dehydration include decreased urination or dark, strong-smelling urine. Also, do not take any other medicines to treat diarrhoea without consulting your doctor. If the condition persists or worsens, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DIX0001

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