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compositionComposition:FLUPIRTINE-400MG
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Prescription Medicine
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Do-Lupat SR-400 Tablet 10's is used to provide relief from mild to moderate pain and inflammation associated with musculoskeletal pain. It contains Flupirtine, which exerts dual effects by relaxing muscles and treating pain. It works by blocking the signals responsible for the sense of pain and inflammation. In some cases, it may cause common side effects like dizziness, drowsiness, pruritus (itchy skin), dry mouth and gastric fullness, nausea and muscle tremor. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLUPIRTINE-400MG

Manufacturer/Marketer :

Dowell Pharmaceutical

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Do-Lupat SR-400 Tablet 10's

Do-Lupat SR-400 Tablet 10's is a prescription medication used to manage moderate, acute pain in adults. It is typically prescribed when other suitable pain-relieving medicines are not appropriate or have not provided adequate relief. This medicine is intended only for short-term use and should not be used as a long-term treatment option. Because of its risk of serious liver injury, Do-Lupat SR-400 Tablet 10's is available only in selected countries and should be used under close medical supervision.

To achieve the best results, take Do-Lupat SR-400 Tablet 10's exactly as prescribed by your doctor. It is usually taken at set times throughout the day and can be taken with or without food. Getting enough rest and performing gentle, low-impact stretches may also support your recovery.
While taking Do-Lupat SR-400 Tablet 10's, you may experience mild side effects such as drowsiness, dry mouth, or dizziness. Seek immediate medical attention if you notice signs of liver damage, including yellowing of the skin or eyes, dark urine, or severe upper abdominal pain.

Do not take this medicine if you have active liver disease, myasthenia gravis (a condition that causes severe muscle weakness), a seizure disorder such as epilepsy, or a history of alcohol abuse. Before starting treatment, tell your doctor if you have kidney problems or are over 65 years of age, as you may require closer monitoring or a lower dose.

Do-Lupat SR-400 Tablet 10's may interact with alcohol and medicines that cause drowsiness or affect the liver. Pregnant or breastfeeding individuals should not take this medicine. Do-Lupat SR-400 Tablet 10's is not approved for use in children or adolescents and should only be used in adults under the supervision of a healthcare professional.
 

Uses of Do-Lupat SR-400 Tablet 10's

Do-Lupat SR-400 Tablet 10's is used for the short-term management of moderate acute pain and related musculoskeletal conditions. It may be prescribed for the following conditions:

  • Acute pain relief: Do-Lupat SR-400 Tablet 10's is used to treat moderate, short-term pain resulting from muscle strains, injuries, or surgical procedures.
  • Muscle spasms: It helps ease painful and tense muscles by relaxing the physical tightness associated with spinal or orthopaedic conditions.
  • Alternative pain management: It is prescribed for patients who cannot tolerate other common pain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs).
     

Key Benefits

Do-Lupat SR-400 Tablet 10's helps relieve moderate, acute pain by reducing pain signals and relaxing tense muscles. It improves comfort and mobility, allowing you to perform daily activities more easily.

  • Provides Effective Pain Relief: Helps reduce persistent pain caused by musculoskeletal conditions and other painful disorders.
  • Relieves Muscle Tension: Helps relax muscle stiffness and spasms, improving movement and reducing discomfort.
  • Improves Mobility: By reducing pain and muscle tightness, it helps you carry out daily activities with greater ease.
  • Supports Recovery: Better pain control allows you to participate more comfortably in physiotherapy and rehabilitation exercises.
  • Offers an Alternative Pain Management Option: Acts through a different mechanism than opioid medicines and nonsteroidal anti-inflammatory drugs (NSAIDs), making it a treatment option in selected patients when appropriate.
     

Directions for Use

  • Take Do-Lupat SR-400 Tablet 10's with food to avoid stomach upset or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Do-Lupat SR-400 Tablet 10's Works

Do-Lupat SR-400 Tablet 10's contains flupirtine, a centrally acting pain-relieving medicine that works by opening selective potassium channels in nerve cells. This helps stabilise the electrical activity of the nerves and reduces the transmission of pain signals to the brain. It is also believed to indirectly reduce the activity of NMDA receptors, which may contribute to its pain-relieving and muscle-relaxing effects. Through these actions, it helps relieve pain, relax tense muscles, and improve overall comfort.
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Alcohol

Caution

You are recommended not to consume alcohol along with Do-Lupat SR-400 Tablet 10's to avoid unpleasant side-effects of this medicine.

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Pregnancy

Unsafe

Do-Lupat SR-400 Tablet 10's is not recommended during pregnancy as safety and efficacy of Do-Lupat SR-400 Tablet 10's is not established. However, your doctor may prescribe Do-Lupat SR-400 Tablet 10's for you during pregnancy if he/she feels the benefit to you outweighs the risk.

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Breast Feeding

Caution

While Do-Lupat SR-400 Tablet 10's may pass in the breast milk of lactating mother so, it is advisable to take it only if prescribed by your doctor.

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Driving

Unsafe

In some cases, Do-Lupat SR-400 Tablet 10's may cause dizziness and drowsiness. So if you observe such symptoms immediately stop the intake of Do-Lupat SR-400 Tablet 10's.

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Liver

Unsafe

It is advised to consult with a doctor as this medicine can not be used in persons dealing with liver problems.

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Kidney

Caution

A person dealing with kidney problems should take Do-Lupat SR-400 Tablet 10's only after consulting with a doctor.

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Children

Unsafe

Do-Lupat SR-400 Tablet 10's not recommended for children under 12 years of age.

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Heart

Consult your doctor

Limited studies available for the use of Do-Lupat SR-400 Tablet 10's in heart patients. Consult your physician.

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Geriatrics

Caution

Do-Lupat SR-400 Tablet 10's should be used in elderly patients with proper monitoring and individualised care.

What if I have taken an overdose of Do-Lupat SR-400 Tablet 10's

If you suspect an overdose, seek immediate emergency medical attention or contact a poison control centre. Symptoms of an overdose may include severe drowsiness, confusion, dry mouth, or rapid heart rate.

Diet & Lifestyle Advise

  • Avoid Alcohol: Do not drink alcohol while taking Do-Lupat SR-400 Tablet 10's, as it may increase the risk of liver damage and excessive drowsiness.
  • Stay Well-Hydrated: Drink plenty of water throughout the day to support your overall health and maintain adequate hydration.
  • Remain Physically Active: Perform gentle stretching, low-impact exercise, or physiotherapy as recommended by your doctor to maintain flexibility and aid recovery.
  • Eat a Balanced Diet: Consume a nutritious diet to support healing. If the medicine causes stomach discomfort, try taking it with a light meal, if advised by your doctor.
     
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Have a query?

How Soon It Starts Working

The time required for Do-Lupat SR-400 Tablet 10's to start to work: Do-Lupat SR-400 Tablet 10's ideally shows its action within 15 to 30 minutes after administration. The time for which the effects of Do-Lupat SR-400 Tablet 10's last: The duration of action for Do-Lupat SR-400 Tablet 10's is unknown.

What if you forget to take Do-Lupat SR-400 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Do-Lupat SR-400 Tablet 10's at room temperature, strictly between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Use Only for the Prescribed Duration: Do not take Do-Lupat SR-400 Tablet 10's for longer than two weeks, as prolonged use increases the risk of serious liver injury.
  • Watch for Signs of Liver Problems: If you notice yellowing of the skin or eyes, dark or brownish urine, severe upper abdominal pain, or loss of appetite, stop taking Do-Lupat SR-400 Tablet 10's immediately and seek urgent medical attention. For all other situations, do not stop the medicine without your doctor's advice.
  • Attend Recommended Monitoring: If your treatment continues beyond a short period, your doctor may recommend regular liver function tests. The timing and frequency of these tests depend on your individual risk factors and treatment plan.
  • Avoid Alcohol and Check Other Medicines: Alcohol and medicines that can affect the liver, such as paracetamol, may increase the risk of liver injury. Tell your doctor or pharmacist about all the medicines and supplements you are taking before starting Do-Lupat SR-400 Tablet 10's.
  • Use Caution with Activities Requiring Alertness: Do-Lupat SR-400 Tablet 10's may cause drowsiness or dizziness. Avoid driving, cycling, or operating machinery until you know how the medicine affects you.
     

verifiedApollotooltip

Do-Lupat SR-400 Tablet 10's may interact with certain medicines, increasing the risk of side effects or affecting treatment safety. Inform your doctor if you are taking any of the following:

  • Blood thinners: May increase the clinical effects of anticoagulant medications, raising the risk of bruising or bleeding.
  • Sedatives and sleep aids: Combining this medicine with drugs that slow brain activity can cause dangerous levels of sleepiness and shallow breathing.
  • Other liver-processed drugs: Using Do-Lupat SR-400 Tablet 10's together with medicines such as paracetamol may place additional strain on the liver. Your doctor will decide whether these medicines can be used together and may recommend closer monitoring if needed.
     

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verifiedApollotooltip

Certain foods and beverages may affect the safety of Do-Lupat SR-400 Tablet 10's. Keep the following in mind:

  • Alcohol: Drinking alcohol while on this medication severely increases the risk of toxic liver damage and intense drowsiness.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Do-Lupat SR-400 Tablet 10's is used to provide relief from mild to moderate pain and inflammation associated with musculoskeletal pain.
Do-Lupat SR-400 Tablet 10's can be stopped if it is advised for short-term pain relief only. In the case of long term usage, it is advised to continue as advised by your doctor.
This medication must be taken every day or as prescribed by your doctor in order for it to benefit you.
Do-Lupat SR-400 Tablet 10's is used to relieve menstrual (period) pain, symptoms of premenstrual syndrome (PMS) and management of excessively heavy periods. Take only as prescribed by the doctor
Do not take Do-Lupat SR-400 Tablet 10's if you are planning for pregnancy as Do-Lupat SR-400 Tablet 10's might make it more difficult to get pregnant.
A person dealing with kidney problems, over 65 years of age or taking blood clotting (anticoagulants) medicines should only take Do-Lupat SR-400 Tablet 10's after consulting with the doctor. A person with liver problems (like hepatic encephalopathy), gall bladder problems (like cholestasis), muscle problems (like myasthenia gravis), chronic alcoholism and biliary cirrhosis should avoid use of Do-Lupat SR-400 Tablet 10's, unless prescribed by a doctor.
Persons taking Do-Lupat SR-400 Tablet 10's may have false-positive results for urobilinogen, bilirubin and urine protein on urine test strips. So tell your lab assistant or doctor that you are taking Do-Lupat SR-400 Tablet 10's before undergoing these diagnostics tests.
It is advised to avoid taking Do-Lupat SR-400 Tablet 10's with medications containing paracetamol or carbamazepine as it can increase the sedative or muscle-relaxant properties of the medication.
Do-Lupat SR-400 Tablet 10's may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, dizziness, heartburn, loss of appetite or constipation. If these side effects persist or worsen, please consult your doctor.
Although some clinical studies suggest that Do-Lupat SR-400 Tablet 10's is beneficial in the treatment of fibromyalgia, it did not get any official regulatory approval for this condition. Fibromyalgia is a disease characterized by musculoskeletal pain, depression and fatigue (overtiredness).
Both Do-Lupat SR-400 Tablet 10's and paracetamol help in relieving pain but they work in completely different ways. Compared to single drug use, pain relief is better when paracetamol is used with Do-Lupat SR-400 Tablet 10's. However, both can cause liver toxicity, thus liver function monitoring is very important when these medicines are taken together.
Yes, Do-Lupat SR-400 Tablet 10's causes liver toxicity. Therefore, it is contraindicated in patients with an underlying liver disease.
Do-Lupat SR-400 Tablet 10's can be used for the pain relief associated with osteorthritis and pain following orthopedic surgery. It is especially useful for patients who are unable to take NSAIDs due to the risk of NSAID-induced gastritis.
There have been case reports that Do-Lupat SR-400 Tablet 10's causes green discoloration of urine. However, this is not frequently observed. If you experience this symptom, inform your doctor.
Yes, you can experience withdrawal symptoms once you stop using Do-Lupat SR-400 Tablet 10's such as tremor, sweating, and mood swings with long term use of Do-Lupat SR-400 Tablet 10's. If you have these symptoms, inform your doctor.
No, Do-Lupat SR-400 Tablet 10's is strictly intended for acute, short-term pain relief (usually up to two weeks) due to the risk of liver damage with longer use. Talk to your doctor about long-term pain management options.
No, Do-Lupat SR-400 Tablet 10's is a non-opioid pain reliever that works differently from opioid medicines. Although its risk of physical dependence is generally considered lower than that of opioids, it should only be used exactly as prescribed and for the recommended duration because of its important safety risks, including serious liver injury.
You should avoid taking paracetamol or other medicines that strain the liver while taking this drug, unless explicitly permitted by your doctor. Talk to your doctor to find a safe combination of medications.
Stop taking Do-Lupat SR-400 Tablet 10's immediately and seek urgent medical care. Yellowing of the eyes or skin is a sign of liver damage. Talk to your doctor right away.
No, you must avoid all alcohol during treatment. Alcohol combined with this medicine greatly increases the risk of severe liver damage and extreme sleepiness. Talk to your doctor if you find it difficult to avoid alcohol.
Yes, drowsiness is a very common side effect. Avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if the sleepiness is severe or interferes with your safety.
No, Do-Lupat SR-400 Tablet 10's is generally not recommended during pregnancy or breastfeeding as there is insufficient safety data. Talk to your doctor to discuss safer pain relief alternatives.
Your doctor may recommend regular liver function tests while you are taking Do-Lupat SR-400 Tablet 10's, particularly if treatment continues beyond a short period. The timing and frequency of these tests depend on your individual risk factors and treatment plan. Always attend any blood test appointments recommended by your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Kapoor Market 38, Girdhar Biulding, Police Lane, Mumbai, Jalandhar 144022, Punjab, Andheri East, Mumbai - 400069
Other Info - DOL0686

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