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Dolobrake MR 500mg/50mg/325mg Tablet

Dolobrake MR 500mg/50mg/325mg Tablet

Prescription drug
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Dolobrake MR 500mg/50mg/325mg Tablet

Dolobrake MR 500mg/50mg/325mg Tablet is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long-term (chronic) in nature. Musculoskeletal pain can be caused due to soft tissue (muscle, tendon, and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Dolobrake MR 500mg/50mg/325mg Tablet is a fixed-dose combination composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. The third medicine, Chlorzoxazone, is a muscle relaxant that helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Dolobrake MR 500mg/50mg/325mg Tablet can be taken with or after the meal. To avoid stomach upset Dolobrake MR 500mg/50mg/325mg Tablet can be taken with food or milk. It should be swallowed whole with a glass of water. Do not take Dolobrake MR 500mg/50mg/325mg Tablet if your pain lasts for more than ten days or if the fever lasts for more than three days. Do not take a double dose if you missed one dose. Like all medicines, Dolobrake MR 500mg/50mg/325mg Tablet may cause side effects, although not everybody gets them. Most of the side effects of Dolobrake MR 500mg/50mg/325mg Tablet are drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. In case of any discomfort, speak with your doctor. 

Do not take Dolobrake MR 500mg/50mg/325mg Tablet if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Dolobrake MR 500mg/50mg/325mg Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Dolobrake MR 500mg/50mg/325mg Tablet

Treatment of Musculoskeletal pain.

Medicinal Benefits

Dolobrake MR 500mg/50mg/325mg Tablet is composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. The third medicine, Chlorzoxazone, is a muscle relaxant that helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Directions for Use

Take Dolobrake MR 500mg/50mg/325mg Tablet as advised by your doctor. Preferably take it with a light meal. Swallow it as a whole; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dolobrake MR 500mg/50mg/325mg Tablet

  • Drowsiness
  • Constipation
  • Diarrhoea
  • Stomach upset
  • Slight discolouration of urine
  • Ringing or buzzing sounds in the ears

Drug Warnings

Intake of Dolobrake MR 500mg/50mg/325mg Tablet should be avoided in liver disease (like jaundice) and cardiovascular disease (like coronary heart disease). Contact your doctor if you have signs of liver disease like feeling exhausted, dark urine, not feeling hungry, stomach pain or upset, light coloured stools or yellow skin/eyes. After taking if you have possible allergic symptoms like difficulty in breathing, difficulty in swallowing, lips/face/throat swelling, chest tightness, or skin rash, contact the doctor immediately. Ensure your doctor is aware if you are pregnant or planning to get pregnant, breastfeeding, allergic to Dolobrake MR 500mg/50mg/325mg Tablet or any other painkillers like aspirin, the problem of stomach ulcer or gastric bleeding, or taking any other OTC multivitamins, multi-minerals supplements.

Drug Interactions

Drug-Drug Interaction: Dolobrake MR 500mg/50mg/325mg Tablet is shown to interact with various drugs. Some of them include pain killers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), blood pressure-related drugs (lisinopril, hydrochlorothiazide), blood thinner (rivaroxaban, warfarin), anti-depressant (duloxetine), acidity lowering drug (cimetidine), and steroids (prednisone). These drugs may affect the working of Dolobrake MR 500mg/50mg/325mg Tablet and may alter its efficacy.

Drug-Food Interaction: Excessive intake of caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking Dolobrake MR 500mg/50mg/325mg Tablet. Taking together may lead to drowsiness and dizziness and sleepiness.

Drug-Disease Interaction: Dolobrake MR 500mg/50mg/325mg Tablet should not recommend for people having bleeding disorders, like haemophilia, von Willebrand disease or low blood platelets. Besides this, it should not be given in the condition of liver disease like jaundice, alcoholism and PKU phenylketonuria (birth defect with an excess of protein in the body).

Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LISINOPRIL
  • HYDROCHLOROTHIAZIDE
  • RIVAROXABAN
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE
  • PREDNISONE

Habit Forming

No

Diet & Lifestyle Advise

  • Dolobrake MR 500mg/50mg/325mg Tablet is commonly prescribed for relieving pain in both acute and chronic conditions and in cases of fever. Do not take the drug beyond its suggested dose and frequency.
  • Avoid driving while consuming Dolobrake MR 500mg/50mg/325mg Tablet as it can cause dizziness in some individuals and hamper your focus and reflexes.
  • Avoid concomitant consumption of drugs containing the same chemicals as Dolobrake MR 500mg/50mg/325mg Tablet as it can lead to overdosage and unwanted side effects.
  • Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Dolobrake MR 500mg/50mg/325mg Tablet.
  • Avoid consuming alcohol while you are on Dolobrake MR 500mg/50mg/325mg Tablet.

Special Advise

  • Dolobrake MR 500mg/50mg/325mg Tablet is prescribed for relief from muscle pain and spasms.
  • It can cause drowsiness and hence activities involving focus and attention like driving must be avoided while on this medication.
  • Concomitant usage of alcohol with this medicine increase the risk of damage to liver and other side effects and hence alcohol consumption should be avoided while consuming this medication.
  • Avoid simultaneous consumption of other painkillers or cough and cold medicines with this Dolobrake MR 500mg/50mg/325mg Tablet as it may lead to overdose.

Disease/Condition Glossary

Musculoskeletal pain is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports-related injuries) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused by sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal.

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Alcohol

Caution

Alcohol should not be consumed with Dolobrake MR 500mg/50mg/325mg Tablet as it leads to excessive drowsiness

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Pregnancy

Caution

Only consume Dolobrake MR 500mg/50mg/325mg Tablet, if you are prescribed by a doctor

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Breast Feeding

Caution

Dolobrake MR 500mg/50mg/325mg Tablet does not pass on to the child significantly via breast milk, consult your doctor before using Dolobrake MR 500mg/50mg/325mg Tablet.

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Driving

Caution

Dolobrake MR 500mg/50mg/325mg Tablet may affect driving ability as it causes dizziness.

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Liver

Caution

Dolobrake MR 500mg/50mg/325mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Dolobrake MR 500mg/50mg/325mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Dolobrake MR 500mg/50mg/325mg Tablet is not recommended for children below 12 years of age without doctor's consent. For children above 12 years, dose to be adjusted and recommended by a child specialist only.

Country of origin

India

Manufacturer/Marketer address

51- 51A, A/1, Mandirippan Street Sidhapudur Coimbatore Coimbatore Tn 641044 In
Other Info -

Author Details

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FAQs

Dolobrake MR 500mg/50mg/325mg Tablet is used to treat musculoskeletal pain due to tissue injury, post-surgery inflammation and oedema (swollen tissue with fluid).
No, Dolobrake MR 500mg/50mg/325mg Tablet should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Dolobrake MR 500mg/50mg/325mg Tablet, take it in doses and duration mentioned by your doctor.
No, it is not advisable to take Dolobrake MR 500mg/50mg/325mg Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Dolobrake MR 500mg/50mg/325mg Tablet.
Yes, Dolobrake MR 500mg/50mg/325mg Tablet is a short term medication and if you feel better you can stop taking Dolobrake MR 500mg/50mg/325mg Tablet, but only after consulting your doctor.
Dolobrake MR 500mg/50mg/325mg Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.
No, Dolobrake MR 500mg/50mg/325mg Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Dolobrake MR 500mg/50mg/325mg Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.
It depends on whether your cough and cold pills contains diclofenac, paracetamol and Chlorzoxazone or not. If it contains these three medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.
No, do not take Dolobrake MR 500mg/50mg/325mg Tablet until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen or gallbladder problem. Your back pain may be due to kidney stone, pancreas swelling, or in women, pelvic disorders. Your arm pain (especially left arm) may be due to heart attack (myocardial infarction).

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