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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Lincoln Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Domi Up Spray

Domi Up Spray is an antiemetic medicine. It is used to prevent nausea and vomiting associated with moderately emetogenic cancer chemotherapy and radiotherapy in children. It is also used to treat nausea and vomiting caused by stomach problems and surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body's forceful discharge of the stomach contents.

Domi Up Spray contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, Domi Up Spray prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Domi Up Spray may cause certain side effects in your child, such as feeling of warmth, headache, diarrhoea, and stomach pain. These side effects generally resolve over time. However, if it does not resolve, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of Domi Up Spray to the child. Domi Up Spray can be given with or without food. Your paediatrician will decide the dose of the medicine.

Domi Up Spray is intended for paediatric use only. Avoid giving Domi Up Spray to your child if she/he is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor if your child has liver and kidney problems.

Uses of Domi Up Spray

Domi Up Spray is used in the prevention of Nausea and Vomiting. The detailed uses of Domi Up Spray are as follows:<br/>•Postoperative Nausea and Vomiting Relief: Domi Up Spray is commonly used to alleviate nausea and vomiting experienced by patients after surgical procedures, often caused by anesthesia.<br/>•Supportive Care in Palliative Settings: Domi Up Spray provides relief for nausea and vomiting in palliative care patients, helping to improve comfort amidst challenges from underlying conditions or treatment side effects.<br/>

Directions for Use

• Domi Up Spray can be administered with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe.• Shake well before use.

Medicinal Benefits

Domi Up Spray contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, Domi Up Spray prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

How Domi Up Spray Works

Domi Up Spray contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, Domi Up Spray prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Storage

Store in a cool and dry place away from sunlight
Side effects of Domi Up Spray 15ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid rubbing or scratching the affected area, as this can cause further irritation and discomfort.
  • Consider using a humidifier to add moisture to the air and help reduce the sensation.
  • Seek medical attention if the sensation is severe, persistent, or worsens over time.
  • Avoid extreme temperatures, such as hot or cold showers, that can exacerbate the sensation.
  • Wear light, breathable clothing to help keep the body cool and reduce the sensation.
  • Avoid triggers that can cause the sensation, such as spicy foods or hot drinks.
  • Use cool compresses or fans to help lower body temperature and reduce the sensation.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Domi Up Spray

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Domi Up Spray may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid giving Domi Up Spray to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease. This medicine is intended for only the paediatric population. Hence, it is not recommended for use in special populations (pregnant and breastfeeding mothers) and adults.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Domi Up Spray 15ml:
Taking Domi Up Spray 15ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Domi Up Spray 15ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Domi Up Spray 15ml:
Taking Domi Up Spray 15ml with disopyramide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Domi Up Spray 15ml along with disopyramide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMaprotiline
Severe
How does the drug interact with Domi Up Spray 15ml:
When Domi Up Spray 15ml is taken with maprotiline, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Domi Up Spray 15ml along with maprotiline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Domi Up Spray 15ml:
Taking Domi Up Spray 15ml with amisulpride increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of amisulpride along with Domi Up Spray 15ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Domi Up Spray 15ml:
When Domi Up Spray 15ml, is taken with eletriptan it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Domi Up Spray 15ml along with eletriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Domi Up Spray 15ml:
Co-administration of Domi Up Spray 15ml and Dextromethorphan may increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Domi Up Spray 15ml and Dextromethorphan, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as seizures (fits), extreme changes in blood pressure, confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, tremors, incoordination, blurred vision, muscle spasms or stiffness, nausea, vomiting, stomach cramp, and diarrhea, contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Domi Up Spray 15ml:
When Domi Up Spray 15ml, is taken with almotriptan it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Domi Up Spray 15ml along with almotriptan can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronVandetanib
Severe
How does the drug interact with Domi Up Spray 15ml:
Taking Domi Up Spray 15ml with vandetanib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Domi Up Spray 15ml along with vandetanib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Domi Up Spray 15ml:
Taking ceritinib together with Domi Up Spray 15ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Domi Up Spray 15ml along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Domi Up Spray 15ml:
Taking Domi Up Spray 15ml with nilotinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Domi Up Spray 15ml along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Certain food items/medicines are known to cause nausea/vomiting to your child.
  • Make your child drink more fluids to avoid dehydration.
  • Providing your child with a healthy diet that includes lots of fruits and vegetables, nuts, and low-fat dairy products will help keep your child in good health and avoid chances of nausea and vomiting. 
  • Avoid giving greasy or oily foods to your child, as this food triggers nausea and vomiting.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this. Your paediatrician will weigh the benefits and risks before prescribing Domi Up Spray to your child.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this. Your paediatrician will weigh the benefits and risks before prescribing Domi Up Spray to your child.

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Children

Safe if prescribed

Domi Up Spray is safe for children above 4 years of age if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

Have a query?

FAQs

Domi Up Spray is used to treat vomiting.

Domi Up Spray contains Ondanestron; that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body which is responsible for causing nausea and vomiting.

Use Domi Up Spray for as long as your paediatrician suggested.

Country of origin

INDIA

Manufacturer/Marketer address

LINCOLN HOUSE, B/h. Satyam Complex, Science City Road, Sola, Ahmedabad – 380 062., Gujarat, India,
Other Info - DOM0203

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