Domine 25mg/500mg Tablet
MRP ₹32
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About Domine 25mg/500mg Tablet
Domine 25mg/500mg Tablet is an antimalarial medicine used to treat malaria. Malaria is a parasitic disease caused by the Plasmodium species. The infection occurs when a mosquito bites and enters the human body. Domine 25mg/500mg Tablet is also used to treat toxoplasmosis (an infection caused by the parasite Toxoplasma gondii).
Domine 25mg/500mg Tablet contains Pyrimethamine and Sulphadoxine as active ingredients. Pyrimethamine kills the parasite and stops the infection from spreading. Sulphadoxine helps prevent the parasite from producing folinic acid, which is necessary for its multiplication.
Domine 25mg/500mg Tablet may cause certain side effects such as nausea, dizziness, vomiting, headache, diarrhoea, anorexia, body pain, and stomach discomfort. If these side effects persist, inform your doctor immediately. Domine 25mg/500mg Tablet should be taken as advised by your doctor.
Domine 25mg/500mg Tablet should be avoided if you are allergic to it or any other artemisinin derivatives. Before taking $ name, inform your doctor if you have/had any conditions such as anaemia, liver/kidney disease, heart problem, or are taking any other medicines, as it may cause serious side effects under these conditions. If you are pregnant or breastfeeding, inform your doctor before taking Domine 25mg/500mg Tablet.
Uses of Domine 25mg/500mg Tablet
Domine 25mg/500mg Tablet is used in the treatment of Malaria. The detailed uses of Domine 25mg/500mg Tablet are as follows:
- Treatment of malaria: Domine 25mg/500mg Tablet is used to treat malaria infections caused by Plasmodium parasites, especially Plasmodium falciparum.
- Prevention of malaria recurrence: Domine 25mg/500mg Tablet helps stop the reproduction of parasites to reduce the risk of relapse and reinfection.
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Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
- Take the prescribed dose by mouth using the measuring cup or dosing syringe.
- Shake the bottle well before each use.
Key Benefits
Domine 25mg/500mg Tablet is a combination medicine containing Pyrimethamine and Sulphadoxine as active ingredients. Pyrimethamine works by increasing the harmful, toxic, and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading. Sulphadoxine helps prevent the parasite from producing folinic acid, which is necessary for their multiplication. Domine 25mg/500mg Tablet is used to prevent the relapse of malaria caused by plasmodium species.
How Domine 25mg/500mg Tablet Works
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- Eat foods rich in vitamins C and E, and healthy fats.
- Consider soft foods like smoothies, soups, and scrambled eggs.
- Take supplements like vitamins C and E, zinc, and omega-3 fatty acids under medical supervision.
- Include anti-inflammatory foods like omega-3 rich foods, berries, leafy greens, and spices.
- Avoid allergens and consider an elimination diet.
- Practice gentle skin care with non-irritating cleansers and moisturizers.
- Keep skin well-moisturized with fragrance-free products.
- Monitor for complications like infection and temperature regulation.
- Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
- Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
- Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
- Apply cold packs to the affected areas for relief.
- Keep yourself hydrated or take supplements to get enough vitamins.
- Over-the-counter pain relievers can help with discomfort.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
- Get sufficient sleep and manage stress which helps in improving white blood cell count.
- Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
- Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
- If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
- Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
- Your doctor will evaluate the severity of the reaction and determine the best course of action.
- To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
- Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
- Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
- Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
- Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
- If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
- In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
- Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
- If you experience severe bleeding or bruising, seek emergency medical attention immediately.
What if I have taken an overdose of Domine 25mg/500mg Tablet
Drug Warnings
Avoid using Domine 25mg/500mg Tablet if you are allergic to it or any other artemisinin derivatives. Inform your doctor if you have/had any conditions such as liver/kidney disease, heart problems, or taking any other medicines before receiving Domine 25mg/500mg Tablet as it may cause serious side effects under these conditions. Domine 25mg/500mg Tablet is recommended for use in children only if prescribed by the paediatrician, and if administered, proper care and dosing should be checked. This medicine is contraindicated in patients with folic acid deficiency. It is advised not to use Domine 25mg/500mg Tablet for more than two years. Avoid driving and operating machines until you are alert.
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Diet & Lifestyle Advise
- It is important to allow the patient to eat regularly in small amounts to tolerate the food.
- Try to add protein to your diet for malaria-induced weight loss.
- Eating at the right time and getting proper rest is important for the patient to recover.
- Avoid eating fried and processed foods, and junk oily and spicy foods can aggravate nausea and disturb the body's digestion process.
- Eat nutritious food that helps to improve malaria-induced weakness.
- Keep your area and surroundings mosquito-free. Use mosquito-repellent products to avoid the recurrence of infections and any other further complications.
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Alcohol
Safe if prescribed
The interaction of Domine 25mg/500mg Tablet with alcohol is unknown. Please consult your doctor.
Pregnancy
Consult your doctor
If you are pregnant or planning pregnancy, inform your doctor before receiving Domine 25mg/500mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Pyrimethamine is excreted in human milk. Therefore, if you are breastfeeding, inform your doctor before receiving Domine 25mg/500mg Tablet. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
Safe if prescribed
Domine 25mg/500mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery after taking Domine 25mg/500mg Tablet until you are alert.
Liver
Consult your doctor
Domine 25mg/500mg Tablet should be used with caution if you have a pre-existing or a history of liver disease. Your doctor may adjust the dose based on your condition.
Kidney
Consult your doctor
Domine 25mg/500mg Tablet should be used with caution if you have a pre-existing or a history of kidney disease. Your doctor may adjust the dose based on your condition.
Children
Safe if prescribed
Please consult your doctor. Your child's doctor will decide the dose of this medicine based on the age and condition of the child.
Heart
Domine 25mg/500mg Tablet should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Domine 25mg/500mg Tablet.
Geriatrics
Consult your doctor
Please consult a doctor before administering Domine 25mg/500mg Tablet to geriatric patients, as limited safety data is available for this age group.
FAQs
Domine 25mg/500mg Tablet is used to treat Malaria and Toxoplasmosis.
Domine 25mg/500mg Tablet contains Pyrimethamine (which kills the parasite and stops the infection from spreading) and Sulphadoxine (which helps prevent the parasite from producing folinic acid, which is necessary for their multiplication).
No, do not stop taking Domine 25mg/500mg Tablet. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve. Failure to do so might result in drug resistance, and treating any subsequent infection with the same medicine would be very difficult.
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