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  3. Domini 10mg Tablet 100's

Domini 10mg Tablet 100's, Pack of 1 TABLET
Domini 10mg Tablet 100's, Pack of 1 TABLET
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Domini 10mg Tablet is used to treat nausea and vomiting in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. It contains Domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. The most common side effect of this medicine is dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DOMPERIDONE-10MG

Manufacturer/Marketer :

Omnison Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Domini 10mg Tablet

Domini 10mg Tablet is used to treat nausea (feeling sick) and vomiting (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Domini 10mg Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Domini 10mg Tablet as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Domini 10mg Tablet . However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Domini 10mg Tablet for longer than seven days. The most common side effect of Domini 10mg Tablet is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Domini 10mg Tablet if you are hypersensitive to any components present in Domini 10mg Tablet . Before taking the Domini 10mg Tablet , inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Domini 10mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or those taking doses higher than 30 mg daily. Domini 10mg Tablet is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Domini 10mg Tablet .

Uses of Domini 10mg Tablet

Domini 10mg Tablet is used in the treatment of nausea and vomiting. The detailed uses of Domini 10mg Tablet are as follows:
• Nausea Relief: Domini 10mg Tablet is commonly used to relieve nausea and vomiting caused by various conditions, including motion sickness and post-operative effects.
• Gastroesophageal Reflux Disease (GERD): Domini 10mg Tablet helps in managing symptoms related to GERD by reducing stomach acid and promoting gastric emptying, which can alleviate discomfort.
• Functional Dyspepsia: Domini 10mg Tablet can aid in the treatment of functional dyspepsia, providing relief from bloating, early satiety, and stomach discomfort.
• Gastroparesis: For patients with delayed gastric emptying (gastroparesis), Domini 10mg Tablet can assist in stimulating gastric motility, thus improving symptoms related to indigestion and fullness.

Directions for Use

  • Swallow it as a whole with water; do not crush, break or chew it.
  • Check the label for directions before use.
  • Do not crush or chew the medicine before swallowing.

Medicinal Benefits

Domini 10mg Tablet contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Domini 10mg Tablet also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

How Domini 10mg Tablet Works

Domini 10mg Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Storage

Store in a cool and dry place away from sunlight
Side effects of Domini 10mg Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Eat a balanced diet rich in fruits, vegetables, whole grains, and healthy fats.
  • Engage in regular moderate exercise, avoiding excessive strenuous activity.
  • Practice relaxation techniques like deep breathing, meditation, or yoga to manage stress.
  • Ensure adequate sleep and hydration.
  • Track your menstrual cycle to monitor patterns and symptoms.
  • Increase calorie intake and aim for a healthy energy balance.
  • Prioritize healthy fats annd take omega-3 rich foods like fatty fish, avocado, nuts, and seeds.
  • Eat complex carbohydrates like whole grains like brown rice, quinoa, whole wheat bread, and oats.
  • Ensure adequate protein intake like lean protein sources like chicken, fish, beans, lentils, and tofu.
  • Include calcium-rich foods such as dairy products like milk, yogurt, and fortified plant-based options.
  • Consume vitamin D sources like fortified milk, fatty fish, or consider supplementation.
  • Practice relaxation techniques like yoga, meditation, and deep breathing exercises to manage stress.
  • Do moderate exercise and reduce intensity or duration to prevent hormonal disruption.
  • Aim for 7-8 hours of restful sleep each night to help your body and mind recharge.
  • Stay hydrated by drinking plenty of water.
  • Maintain a healthy body weight through balanced diet and exercise.
  • Consult a healthcare professional before making significant dietary changes, especially if suspecting a medical cause for amenorrhea.

What if I have taken an overdose of Domini 10mg Tablet

Do not take more than the prescribed dose of Domini 10mg Tablet as it may cause overdose. The symptoms of overdose include uncontrolled movements which include unusual eye movements, sleepiness, confusion, abnormal posture (such as a twisted neck) or unusual movements of the tongue. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not consume Domini 10mg Tablet if you are allergic to any components present in Domini 10mg Tablet . Before taking the Domini 10mg Tablet , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Domini 10mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Domini 10mg Tablet , immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Domini 10mg Tablet .

Drug-Drug Interactions

verifiedApollotooltip
DomperidoneCisapride
Severe
DomperidoneCitalopram
Severe

Drug-Drug Interactions

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DomperidoneCisapride
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Cisapride can increase the blood levels of Domini 10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Domini 10mg Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domini 10mg Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Domini 10mg Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domini 10mg Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domini 10mg Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Domini 10mg Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domini 10mg Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Domini 10mg Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Ritonavir can increase the blood levels of Domini 10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Domini 10mg Tablet and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Domini 10mg Tablet:
Coadministration of Domini 10mg Tablet with Nefazodone can increase the blood levels of Domini 10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Domini 10mg Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Domini 10mg Tablet:
Combining Mizolastine with Domini 10mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Domini 10mg Tablet and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 

  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.

  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Domini 10mg Tablet Substitute

Substitutes safety advice

  • Aquris Domone-10 Tablet 10's

    by Others

    ₹2.16per tablet

  • Domstal 10 Tablet 10's

    by Others

    ₹2.30per tablet

  • Vomistop Tablet 10's

    by Others

    ₹2.17per tablet

  • Dom-DT 10 Rapitab 10's

    by AYUR

    ₹2.30per tablet

  • Domstal DT 10 Tablet 15's

    by Others

    ₹2.31per tablet

Product Substitutes

bannner image

Alcohol

Unsafe

Drinking alcohol with Domini 10mg Tablet may cause sleepiness, or an irregular heartbeat.

bannner image

Pregnancy

Unsafe

Domini 10mg Tablet is not usually recommended in pregnancy.

bannner image

Breast Feeding

Caution

Domini 10mg Tablet is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

bannner image

Driving

Safe

Domini 10mg Tablet has no effect on your ability to drive or operate machinery.

bannner image

Liver

Caution

Domini 10mg Tablet should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

bannner image

Kidney

Caution

Domini 10mg Tablet should be taken with caution in patients with kidney problems. Your doctor will adjust your dose depending upon the condition of your disease.

bannner image

Children

Caution

Domini 10mg Tablet should not be given to adolescents younger than 12 years of age or are less than 35 kg in weight.

Have a query?

FAQs

Domini 10mg Tablet is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.

Domini 10mg Tablet contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Domini 10mg Tablet as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Domini 10mg Tablet can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Domini 10mg Tablet may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.

If you are have any liver or kidney problem, inform your doctor so that an alternative medicine may be recommended.

You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into esophagus). Also, avoid carbonated drinks such as cold drinks and soda as the carbon dioxide gas in them may worsen acid reflux. Limit your intake of chocolate and mint. Some pain killers such as Ibuprofen may increase acidity and worsen the condition. Thus, avoid using these for prolonged duration.

Take Domini 10mg Tablet only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long term use of Domini 10mg Tablet may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly and if required your doctor may prescribe the supplements for these deficiencies.

Domini 10mg Tablet is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Domini 10mg Tablet . Patients with underlying liver or kidney disease, should use caution.

Yes, the use of Domini 10mg Tablet can cause diarrhoea. In case if you have diarrhoea, drink lots of water or other fluids. Avoid intake of fatty or fried foods along with Domini 10mg Tablet . If diarrhoea persists and if you notice any signs of dehydration, such as decreased urination with dark colored and strong-smelling urine.

Store Domini 10mg Tablet at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.

Yes, Domini 10mg Tablet is safe if used as advised by the doctor. Follow your doctor’s instructions.

It is best to take Domini 10mg Tablet before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.

Take Domini 10mg Tablet as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

You are recommended to take your doctor’s advice before taking Domini 10mg Tablet if you are pregnant or breastfeeding.

Country of origin

India
Other Info - DOM0214

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 15, 2025 | 7:57 AM IST

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Reference

  1. https://www.nhs.uk/medicines/domperidone/
  2. https://www.medicines.org.uk/emc/files/pil.556.pdf
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