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compositionComposition:DOMPERIDONE-1MG/ML
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Prescription Medicine
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOMPERIDONE-1MG/ML

Manufacturer/Marketer :

East African Overseas (I) Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Domriv Drop

Domriv Drop is a medication primarily used to treat nausea, vomiting, and indigestion. It works by speeding up the movement of food through your stomach and digestive tract to relieve feelings of fullness and bloating. Your doctor may prescribe it to manage discomfort caused by slow stomach emptying.

For the best results, you should take this medicine consistently at the exact times prescribed by your doctor, usually 15 to 30 minutes before your meals. Taking it before food helps your body absorb the medication quickly so it can start working to prevent symptoms. Combining this treatment with eating smaller, more frequent meals and avoiding fatty foods can significantly improve your recovery.

While taking Domriv Drop, you might experience mild side effects like a dry mouth or feeling slightly sleepy. These symptoms are usually temporary, but you should consult your doctor immediately if you experience severe dizziness, a rapid heartbeat, or any swelling.

Do not take this if you have a history of heart rhythm disorders, severe liver damage, or blockages in your intestines. It is also not suitable for people with a prolactin-secreting pituitary gland tumour (prolactinoma), as Domriv Drop can increase prolactin levels and may worsen this condition. Always tell your doctor if you have any pre-existing kidney or heart conditions before starting this medicine.

This medicine can interact with certain anti-fungal drugs and antibiotics, which may increase the risk of heart-related side effects. Avoid drinking alcohol while on this medication, as it can worsen drowsiness and stomach irritation. If you are pregnant, breastfeeding, or elderly, you must consult your doctor to ensure this treatment is safe for you.
 

Uses of Domriv Drop

Domriv Drop is used to relieve nausea, vomiting, and digestive symptoms associated with delayed stomach emptying. The detailed uses of Domriv Drop are as follows: 

  • Nausea and vomiting: Domriv Drop blocks the chemical messengers in the brain that trigger the urge to throw up, helping to quickly control nausea and prevent vomiting.
  • Indigestion and bloating: It helps stimulate movement in the upper digestive tract, which reduces the uncomfortable feeling of fullness, bloating, and early satiety after meals.
  • Delayed stomach emptying: By accelerating the passage of food from the stomach into the intestines, it relieves chronic symptoms of slow digestion, such as upper abdominal pain and regurgitation.
     

Key Benefits

Domriv Drop helps relieve nausea and vomiting, making it easier to carry out daily activities without persistent digestive discomfort. By improving stomach emptying and supporting normal digestive movement, it offers several additional benefits:

  • Relieves Nausea and Vomiting: Helps reduce feelings of nausea and the urge to vomit, providing effective symptom relief.
  • Improves Stomach Emptying: Helps food move through the stomach more efficiently, reducing the likelihood of food remaining in the stomach for prolonged periods.
  • Reduces Digestive Discomfort: May help relieve acid reflux, bloating, and the feeling of pressure or fullness after meals.
  • Supports Better Nutrition: By improving tolerance to meals and reducing digestive symptoms, it can help maintain adequate nutrition and body weight during recovery from digestive conditions.

Directions for Use

To get the maximum benefit from Domriv Drop treatment, follow these step-by-step instructions carefully: 

  • Take this medicine orally, usually 15 to 30 minutes before your meals.
  • Taking it on an empty stomach ensures that the medicine is absorbed quickly and can work efficiently when you eat.
  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is released into your system.

Always take Domriv Drop exactly as directed by your healthcare provider. Do not increase your dose or take it for longer than prescribed.
 

How Domriv Drop Works

Domriv Drop contains domperidone, a medicine that belongs to a group of drugs known as prokinetics and dopamine receptor blockers. Dopamine is a natural chemical that can slow down movement in the digestive tract and contribute to feelings of nausea and vomiting. Domriv Drop works mainly by blocking dopamine receptors in the stomach and intestines, which helps increase the movement of food through the digestive system. This promotes faster stomach emptying, reduces bloating and fullness after meals, and helps prevent food and stomach acid from moving back into the oesophagus. Domriv Drop also blocks dopamine receptors in the chemoreceptor trigger zone (CTZ), an area involved in triggering nausea and vomiting that lies outside the blood-brain barrier. Because Domriv Drop has limited penetration into the brain, its effects occur primarily outside the central nervous system. By reducing dopamine-related signals in the CTZ, it helps relieve nausea and prevent vomiting while supporting smoother digestion.
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Alcohol

Unsafe

Drinking alcohol with Domriv Drop may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

Domriv Drop is not usually recommended in pregnancy. However, inform your doctor if you are pregnant or planning for pregnancy before taking Domriv Drop.

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Breast Feeding

Unsafe

Domriv Drop is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

Domriv Drop has no effect on your ability to drive or operate machinery.

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Liver

Caution

Domriv Drop should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them.

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Kidney

Caution

Domriv Drop should be taken with caution in patients with kidney problems. Your doctor will adjust your dose based on the severity of your condition.

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Children

Unsafe

Domriv Drop should not be given to adolescents younger than 12 years of age or who are less than 35 kg in weight.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Domriv Drop. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Domriv Drop should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using Domriv Drop, please consult a doctor.

What if I have taken an overdose of Domriv Drop

Do not take more than the prescribed dose of Domriv Drop as it may cause an overdose. The symptoms of overdose include uncontrolled movements, which include unusual eye movements, sleepiness, confusion, abnormal posture (such as a twisted neck) or unusual movements of the tongue. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Eat smaller, more frequent meals: Instead of three large meals, eat five to six small portions throughout the day to reduce pressure on your stomach.

  • Avoid trigger foods: Limit fatty, spicy, and acidic foods, as well as caffeinated beverages, which can delay stomach emptying and trigger nausea.
  • Stay upright after eating: Do not lie down for at least two hours after a meal to help gravity assist your digestion and prevent acid reflux.
  • Stay hydrated: Sip water or clear fluids throughout the day, especially if you have been vomiting, to prevent dehydration. Avoid drinking large amounts of liquid during meals.

Have a query?

How Soon It Starts Working

  • The time required for Domriv Drop to start to work: The time required for Domriv Drop to start to work is 30 to 60 minutes after administration.
  • The time for which the effects of Domriv Drop last: The effect of Domriv Drop lasts for 6 hours.

What if you forget to take Domriv Drop

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time.

Storage

• Store Domriv Drop tablets at controlled room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Take Before Meals: Always take Domriv Drop before meals, as taking it after food may delay absorption and reduce its effectiveness.
  • Use for the Prescribed Duration Only: Domriv Drop should be used at the lowest effective dose for the shortest duration necessary. The recommended treatment duration varies depending on the condition being treated, and your doctor will determine the appropriate course for you. Prolonged use may increase the risk of heart rhythm problems.
  • Use Caution When Driving: Avoid driving or operating machinery if this medicine makes you feel dizzy or sleepy.
  • Watch for Heart Rhythm Changes: Domriv Drop may rarely affect the heart's electrical activity and increase the risk of serious heart rhythm problems, particularly in older adults, people with existing heart disease, or those taking certain interacting medicines. Seek immediate medical attention if you experience a very fast, pounding, irregular heartbeat, severe dizziness, or fainting.
  • Inform Your Doctor About Other Medicines: Tell your doctor about all medicines you are taking, especially those used for heart conditions, fungal infections, or psychiatric disorders.
     

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Domriv Drop:

  • Certain Antifungals and Antibiotics: Medicines such as ketoconazole and erythromycin may significantly increase Domriv Drop levels in the body and raise the risk of serious heart rhythm problems.
  • Medicines That Affect Heart Rhythm: Avoid taking Domriv Drop with medicines that slow the heart rate or alter the heart's normal rhythm, as this may increase the risk of cardiac side effects.


Drug-Food Interactions

Certain foods and beverages may affect how Domriv Drop works or increase the risk of side effects. Examples include: 

  • High-Fat Meals: Taking this medicine with high-fat meals may delay its absorption and reduce its effectiveness.
  • Grapefruit Juice: Avoid grapefruit juice while taking Domriv Drop, as it may increase the concentration of the medicine in the body and raise the risk of side effects.


Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Domriv Drop, as it may worsen your condition or require additional monitoring:

  • Heart disease: May worsen heart rhythm disorders or pre-existing heart failure.
  • Liver damage: Should be avoided in patients with moderate to severe liver conditions, as the liver processes this drug.
  • Gastrointestinal bleeding or blockage: Do not take if you have bleeding, a tear, or a blockage in your stomach or intestines, as stimulating gut movement can be harmful.
     

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Domriv Drop is used to treat nausea (feeling sick) and vomiting (being sick). Besides this, it also helps in the treatment of indigestion.

Domriv Drop contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Domriv Drop as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Dry mouth is a common and usually harmless side effect. You can manage it by chewing sugar-free gum, sucking on ice chips, or taking frequent sips of water. Talk to your doctor if it becomes highly uncomfortable.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

If you have high blood pressure or any other cardiovascular condition, you must inform your doctor before starting this medicine, as it can occasionally affect heart rhythm. Talk to your doctor to ensure it is safe for you.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Domriv Drop may cause side effects such as dry mouth, headache or diarrhoea. If these side effects persist or worsen, please consult your doctor.

If you have any liver or kidney problems, inform your doctor so an alternative treatment can be recommended.

You are recommended to avoid spicy and oily foods. Limit smoking and alcohol consumption as they may worsen the reflux (stomach acid rising into the oesophagus). Also, avoid carbonated drinks, such as cold drinks and soda, as the carbon dioxide gas they contain may worsen acid reflux. Limit your intake of chocolate and mint. Some painkillers, such as Ibuprofen, may increase acidity and worsen the condition. Thus, avoid using these for prolonged durations.

Take Domriv Drop only for the duration as prescribed by your doctor. If you get relief from your symptoms, consult your doctor for a follow-up, where your doctor may lower the dose. Long-term use of Domriv Drop may cause fractures, low vitamin B12 levels and magnesium levels. You need to be cautious about these and continue to monitor your blood levels regularly. If required, your doctor may prescribe supplements to address these deficiencies.

Domriv Drop is contraindicated in patients with a known hypersensitivity to domperidone or any other inactive ingredients of Domriv Drop. Patients with underlying liver or kidney disease should use caution.

Yes, the use of Domriv Drop can cause diarrhoea. If you have diarrhoea, drink plenty of water or other fluids. Avoid consuming fatty or fried foods with Domriv Drop. If diarrhoea persists and you notice any signs of dehydration, such as decreased urination with dark-coloured, strong-smelling urine.

Store Domriv Drop at room temperature in a cool and dry place. Protect from direct light and moisture. Keep it out of reach of children.

Yes, Domriv Drop is safe if used as advised by the doctor. Follow your doctor’s instructions.

It is best to take Domriv Drop before food. Take it the 15 to 30 minutes before a meal or snack or take it as advised by your doctor.

Take Domriv Drop as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

This medication is generally not recommended during pregnancy unless your doctor decides the benefits outweigh the potential risks. Talk to your doctor if you are pregnant or planning to become pregnant.

Yes, it is highly recommended to take Domriv Drop 15 to 30 minutes before your meals. Taking it on an empty stomach ensures that the medicine is absorbed quickly and works effectively. Talk to your doctor if you have questions about how to time your doses.

This medicine usually starts working within 30 to 60 minutes after you take it. If your symptoms do not improve after a few days, talk to your doctor.

It is best to avoid alcohol while taking this medicine, as alcohol can increase drowsiness and worsen stomach irritation. Talk to your doctor for personalised advice.

It is best to avoid alcohol while taking this medicine, as alcohol can increase drowsiness and worsen stomach irritation. Talk to your doctor for personalised advice.

Yes, some people may experience mild drowsiness or sleepiness while taking this medication. Avoid driving or operating heavy machinery if you feel drowsy. Talk to your doctor if this symptom persists.

Domriv Drop is generally prescribed at the lowest effective dose for the shortest duration necessary. The recommended treatment period depends on the condition being treated and your individual medical needs. Longer treatment courses may be appropriate in certain situations under close medical supervision. Because prolonged use may increase the risk of serious side effects, particularly heart rhythm problems, always follow your doctor's instructions regarding treatment duration.

Domriv Drop may be prescribed for children in certain situations, but the dose must be determined by a doctor based on the child's age, weight, and medical condition. Caregivers should not give this medicine to a child unless specifically instructed by a healthcare professional.

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