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compositionComposition:INDOMETHACIN-25MG
prescription
Prescription Medicine
info
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Donica Capsule is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. It is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery. It contains Indomethacin, which works by reducing the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience certain common side effects, such as headache, dizziness, diarrhoea, vomiting, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INDOMETHACIN-25MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Donica Capsule

Donica Capsule is a prescription medication used to reduce pain, swelling, and joint stiffness caused by moderate to severe arthritis, gout, and other inflammatory conditions. It belongs to a class of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) which target inflammation directly at the source.

For the best results, you should take this medicine consistently at the exact times prescribed by your doctor. It is highly recommended to take Donica Capsule with food, milk, or an antacid to protect your stomach from irritation. Combining this medication with joint-friendly physical therapy and maintaining a healthy weight can significantly improve your mobility.

While taking Donica Capsule , some people may experience mild side effects like dizziness, headache, or a mild upset stomach. However, you must seek medical attention immediately if you notice severe signs such as dark, tarry stools, severe stomach pain, or sudden shortness of breath.

Talk to your doctor before starting Donica Capsule if you have a history of high blood pressure, heart issues, asthma, or kidney disease. Do not take this medicine if you have an active stomach ulcer, severe heart failure, or if you have ever had a severe allergic reaction to aspirin or other pain relievers.

This medicine can interact with blood thinners, water pills, and other pain medicines, which may increase your risk of bleeding or kidney issues. It is best to avoid alcohol and smoking while taking Donica Capsule as they can increase the risk of stomach bleeding. Pregnant women, breastfeeding mothers, and older adults should always consult their healthcare provider before using this medicine.

Uses of Donica Capsule

The detailed uses are as follows:

  • Rheumatoid Arthritis: Donica Capsule helps reduce the painful joint swelling, stiffness, and tenderness caused by this long-term autoimmune condition.
  • Osteoarthritis: It provides effective relief from joint pain and inflammation caused by the progressive wear and tear of cartilage in your joints.
  • Ankylosing Spondylitis: This medicine reduces pain and stiffness in the spine, helping you maintain better posture, flexibility, and physical function.
  • Acute Gouty Arthritis: It quickly targets and eases the severe, sudden pain, redness, and swelling in joints affected by gout flares.
  • Bursitis and Tendinitis: Donica Capsule relieves acute pain and inflammation in the shoulders, elbows, or other joints affected by inflamed tendons or fluid sacs.

Key Benefits

Donica Capsule provides effective pain and inflammation relief to help manage moderate to severe discomfort and improve joint function. By reducing inflammation and supporting easier movement, this medicine offers several key health benefits:

  • Rapid Relief from Pain and Inflammation: Donica Capsule helps reduce swelling and inflammation in affected joints, providing targeted relief that allows you to return to daily activities with greater comfort.
  • Improved Joint Mobility and Flexibility: By easing pain and stiffness, Donica Capsule helps improve movement, making everyday tasks easier and allowing more comfortable participation in physical therapy or strengthening exercises.
  • Better Long-Term Joint Function: By supporting pain control and mobility, Donica Capsule helps maintain physical activity levels and promotes healthier joint function over time.
Side effects of Donica Capsule
  • Prefer liquid food like juices and soups when you are not likely to eat.
  • Avoid spicy, fatty and fried foods as they cause stomach upset.
  • Eat small and frequent meals, avoiding large meals at a time.
  • Add healthy foods in your diet like fruits and vegetables.
  • Take starchy food like cereals, bread and potatoes etc.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Syncope (Loss of consciousness): A Step-by-Step Guide:
  • Let someone you trust know about your medication and the potential risk of loss of consciousness. Ask them to check on you regularly.
  • If you experience loss of consciousness or feel faint, call emergency services or have someone take you to the hospital.
  • Once you're receiving medical attention, inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your doctor may adjust your treatment plan by changing dosage, switching to a different medication, or stopping the medication.
  • Wear a medical alert device, such as a smartwatch or pendant, that can detect falls or other emergencies and alert emergency services.
  • If you're concerned about the risk of loss of consciousness, consult your doctor before it happens to develop a plan to mitigate the risk.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Directions for Use

To ensure you get the maximum benefit from Donica Capsule while protecting your stomach and overall health, please follow these step-by-step instructions:

  • Take this medication by mouth, exactly as directed by your doctor.
  • Swallow the capsule whole with a full glass of water. Do not crush, chew, or open the capsule.
  • Always take this medicine with food, milk, or an antacid to reduce the chance of an upset stomach.
  • Do not lie down for at least 15 to 30 minutes after taking this medication to prevent throat irritation.

Always follow your doctor's exact instructions regarding your dose and how long you should take this medicine. Do not stop taking it or change your dose without consulting your healthcare provider first.

How Donica Capsule Works

Donica Capsule contains indomethacin. It works by blocking the action of specific natural enzymes in your body called cyclooxygenase (COX) enzymes. These enzymes are responsible for producing chemicals known as prostaglandins, which the body releases in response to injury or illness, causing pain, fever, and inflammation. By stopping the production of these prostaglandins, Donica Capsule successfully lowers swelling, eases pain, and cools down localized inflammation. Because it targets the chemical pathways of pain directly at the site of joint or tissue damage, it provides highly effective relief where you need it most.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Donica Capsule . Alcohol intake, along with Donica Capsule , may cause increased dizziness and drowsiness. It may also elevate the risk of stomach bleeding.

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Pregnancy

Unsafe

It is not recommended to take Donica Capsule while you are pregnant. Please consult your doctor if you are pregnant or if you are having any concerns regarding this.

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Breast Feeding

Unsafe

It is not recommended to take Donica Capsule while you are breastfeeding. Please consult your doctor if you are breastfeeding or if you are having any concerns regarding this.

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Driving

Caution

Donica Capsule may cause drowsiness, dizziness, tiredness and vision disturbances, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Donica Capsule should be taken with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems with symptoms of yellowing of skin/eyes, difficulty in peeing or feeling exhausted all the time.

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Kidney

Caution

Dose adjustment may be needed. Donica Capsule should be taken with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Donica Capsule should not be used by children, as the efficacy and safety have not been established.

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Heart

Unsafe

Donica Capsule is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Unsafe

Donica Capsule should be avoided in geriatric patients as it can cause serious adverse effects.

What if I have taken an overdose of Donica Capsule

If you suspect an overdose, or if someone has accidentally swallowed this medicine, seek immediate emergency medical attention or call your local poison control center right away. Symptoms of an overdose may include severe stomach pain, extreme drowsiness, nausea, vomiting, or shallow breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys flush out the medication safely and lower the risk of kidney strain.
  • Eat stomach-friendly meals: Avoid spicy, highly acidic, or greasy foods while taking this medicine to minimize the risk of stomach irritation and heartburn.
  • Apply cold or warm compresses: For joint pain, alternating between ice packs and warm heating pads can soothe inflammation naturally alongside your medication.
  • Engage in low-impact exercise: Activities like swimming, cycling, or walking can keep your joints flexible and strong without putting excessive stress on them.
  • Limit purine-rich foods: If you are taking this medicine for gout, avoid or limit foods like red meat, organ meats, seafood, and alcohol, which can trigger painful gout flares.
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How Soon It Starts Working

The time required for Donica Capsule to start to work: Donica Capsule ideally shows its action within 30 minutes after administration. The time for which the effects of Donica Capsule last: The effect of Donica Capsule lasts for 4 to 6 hours.

What if you forget to take Donica Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Donica Capsule capsules at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medicine in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Monitor your blood pressure: Since this medicine can sometimes raise blood pressure, check your levels regularly while using it.
  • Watch for signs of bleeding: Look out for unusual bruising, dark stools, or pink urine, and report these to your doctor immediately.
  • Avoid other pain relievers: Do not take aspirin, ibuprofen, naproxen, or other NSAIDs while taking Donica Capsule unless specifically advised by your doctor, as this greatly increases the risk of stomach ulcers.
  • Be careful with driving: This medicine can cause dizziness or drowsiness; do not drive or operate machinery until you know how it affects you.
  • Inform your surgeon: If you have an upcoming surgery or dental procedure, tell your doctor or dentist that you are taking this medication, as you may need to stop taking it temporarily.

Drug-Drug Interactions

verifiedApollotooltip

  • Blood thinners (like warfarin): May increase the risk of serious stomach bleeding.

  • Blood pressure medications (like ACE inhibitors or beta-blockers): Donica Capsule can reduce the effectiveness of these medicines.

  • Water pills (diuretics): May increase the risk of kidney damage when taken together.

  • Other NSAIDs (like ibuprofen or aspirin): Can significantly raise the risk of stomach ulcers and bleeding.

  • Lithium: May increase lithium levels in your blood to dangerous levels.

IndometacinKetorolac
Critical
IndometacinCidofovir
Critical

Drug-Drug Interactions

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IndometacinKetorolac
Critical
How does the drug interact with Donica Capsule:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Donica Capsule with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinCidofovir
Critical
How does the drug interact with Donica Capsule:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Donica Capsule with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IndometacinApixaban
Severe
How does the drug interact with Donica Capsule:
Coadministration of Indomethacin and Apixaban may raise the risk of bleeding.

How to manage the interaction:
Taking Indomethacin and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinEtodolac
Severe
How does the drug interact with Donica Capsule:
Taking Indomethacin with Etodolac can increase the risk of side effects (inflammation, bleeding, ulceration, and perforation of the stomach).

How to manage the interaction:
Although there is a possible interaction between Etodolac and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinDabigatran etexilate
Severe
How does the drug interact with Donica Capsule:
Using Indomethacin with Dabigatran etexilate can increase the risk of bleeding.

How to manage the interaction:
Taking Donica Capsule with Dabigatran etexilate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinCelecoxib
Severe
How does the drug interact with Donica Capsule:
Coadministration of Indomethacin with Celecoxib can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Donica Capsule and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
IndometacinEdoxaban
Severe
How does the drug interact with Donica Capsule:
Using Donica Capsule with Edoxaban can increase the risk of bleeding.

How to manage the interaction:
Taking Donica Capsule with Edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IndometacinPiroxicam
Severe
How does the drug interact with Donica Capsule:
Use of Donica Capsule with Piroxicam can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Donica Capsule with Piroxicam together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinAdefovir dipivoxil
Severe
How does the drug interact with Donica Capsule:
Using Indomethacin with Adefovir dipivoxil can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Donica Capsule with Adefovir dipivoxil can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, bone pain, muscle cramps, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.
IndometacinHuman immunoglobulin
Severe
How does the drug interact with Donica Capsule:
Co-administration of Human immunoglobulin with Donica Capsule may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Indomethacin can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking this medicine significantly increases your risk of stomach irritation and bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[GOUT THERAPY]

FAQs

Donica Capsule is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. It is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery.
Donica Capsule works by blocking the effect of chemical messengers (prostaglandin), thereby helps in reducing joint pain, stiffness, swelling and inflammation.
Diarrhoea might be a side-effect of Donica Capsule . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Donica Capsule may increase the risk of heart attack or stroke. Do not use Donica Capsule immediately before or after heart surgery. Consult your doctor before taking Donica Capsule if you have/ had heart problems.
Donica Capsule may affect laboratory test results. Inform the person doing the tests that you are taking Donica Capsule .
Donica Capsule may affect fertility. However, the effect is reversible on stopping Donica Capsule . Consult your doctor before taking Donica Capsule if you are planning to become pregnant. It is important not to become pregnant while using Donica Capsule and for at least 1 month after stopping Donica Capsule as it can cause harm to the unborn baby or fetus. Women can be given a reminder card from the doctor about this.
The common side effects of Donica Capsule include sensitivity to sunlight, dry eyes, dry throat, dry nose and nosebleeds, headaches and general aches and pains.
Yes, Donica Capsule is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate acute pain.
In some cases, you may experience headache as a common side effect. In most cases it does not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience headache persistently.
No, Donica Capsule is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and relieves pain.
Donica Capsule contains Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID).
Inform your doctor about your dietary habits, medications, and underlying health issues. Your doctor will only recommend this if the benefits outweigh the risks.
The recommended dosage may vary depending on your individual needs and the condition being treated. It's best to follow the instructions provided on the product label or as directed by your healthcare provider.
The frequency of intake will depend on your specific situation. Follow the instructions provided or consult with your healthcare provider.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Donica Capsule contains Indomethacin, it has been shown to be an effective.
It is not recommended to take Donica Capsule on an empty stomach. Always take it with food, milk, or an antacid to prevent stomach irritation, heartburn, and ulcers. Talk to your doctor if you experience persistent stomach discomfort.
For acute conditions like gout flares or tendonitis, you may start to feel pain relief within a few hours. For chronic conditions like arthritis, it may take up to a week or more of consistent use to notice a significant reduction in joint swelling and stiffness. Talk to your doctor if your symptoms do not improve.
You should avoid alcohol while taking this medicine. Alcohol increases the risk of serious stomach irritation, ulcers, and gastrointestinal bleeding. Talk to your doctor or pharmacist if you have questions about alcohol use.
You should not take Donica Capsule during the later stages of pregnancy (especially after 20 weeks) as it can harm the unborn baby and cause complications during delivery. Always talk to your doctor before taking any pain relief medication while pregnant or breastfeeding.
Yes, some people may experience drowsiness, dizziness, or a feeling of spinning while taking this medicine. Avoid driving, operating heavy machinery, or performing tasks that require alertness until you know how this medicine affects you. Talk to your doctor if these symptoms persist.
No, you should avoid taking Donica Capsule with other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, or aspirin, as this can severely increase your risk of stomach ulcers and bleeding. Talk to your doctor or pharmacist before combining any pain relievers.
Swelling in your ankles, feet, or hands can be a sign of fluid retention, which is a known risk with this medication, especially in people with heart or kidney conditions. You should contact your doctor right away if you notice any sudden or unusual swelling.
Your doctor will prescribe this medicine for the shortest duration possible to manage your symptoms, as long-term use can increase the risk of heart problems, kidney damage, and stomach ulcers. Talk to your doctor to determine the safest treatment plan for your condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - DON0003

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