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compositionComposition:DOXEPIN-10MG
prescription
Prescription Medicine
info
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Dox 10 mg Tablet is used to treat depression and anxiety when patients become intolerant to other medicines. In addition, it is also given as a medication to treat insomnia (difficulty in sleeping) in some people. It contains Doxepin, which increases the level of chemicals in the brain responsible for mood changes and causing depression. As a result, your mood is enhanced, and you feel better. If it is prescribed for insomnia, it helps us sleep for more time and treats sleeping difficulty. In some cases, you may experience side effects such as drowsiness, dry mouth, increased heart rate, constipation, weight gain, difficulty in urination, and sudden blood pressure lowering on standing up (orthostatic hypotension). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DOXEPIN-10MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Dox 10 mg Tablet

Dox 10 mg Tablet is an oral prescription medication used to manage depression, anxiety, and sleep maintenance difficulties, which involve trouble staying asleep. It belongs to a class of drugs that help restore the balance of certain natural chemicals in the brain to improve your mood, relieve tension, and promote restful sleep.

To achieve the best results, you must take Dox 10 mg Tablet consistently every day exactly as directed by your doctor. This medicine can be taken with or without food, but keeping your routine the same each day helps maintain steady levels of the medication in your body. Combining this treatment with healthy sleep habits or regular counselling can significantly support your overall progress.

While taking Dox 10 mg Tablet , some patients experience mild side effects like drowsiness or dry mouth. However, you should contact your doctor immediately if you notice serious changes in your health, such as severe mood swings, confusion, or a rapid or irregular heartbeat.

Talk to your doctor before starting this medication if you have a history of heart problems, glaucoma, or difficulty urinating. Do not take this if you are recovering from a recent heart attack, have untreated narrow-angle glaucoma, or suffer from severe urinary retention.

This medicine can interact with alcohol, smoking, and other medications like certain allergy or pain relievers, which can significantly increase drowsiness. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to discuss whether this medication is appropriate for you.

Uses of Dox 10 mg Tablet

Dox 10 mg Tablet is used to manage depression, anxiety, and sleep maintenance difficulties. The detailed uses of Dox 10 mg Tablet are as follows:

  • Depression: Dox 10 mg Tablet helps relieve persistent feelings of sadness, low energy, and loss of interest by balancing chemical messengers in the brain.
  • Anxiety: It reduces excessive worry, fear, and physical tension, helping you feel more relaxed during your daily routine.
    Insomnia: When prescribed for sleep difficulties, it helps you stay asleep longer throughout the night and reduces the number of times you wake up.

 

Key Benefits

Dox 10 mg Tablet helps support mental wellbeing by improving symptoms of depression, anxiety, and sleep disturbances. By helping restore the balance of certain brain chemicals, it promotes emotional stability, better daily functioning, and improved quality of life.

  • Helps Improve Mood and Emotional Wellbeing: By addressing chemical imbalances in the brain, Dox 10 mg Tablet helps reduce symptoms of depression and anxiety. This can contribute to a calmer mind, improved emotional balance, and a greater ability to cope with everyday challenges.
  • Supports Better Energy and Daily Functioning: As symptoms become better controlled, Dox 10 mg Tablet may help improve motivation, concentration, and overall energy levels, making it easier to participate in work, social activities, and daily routines.
  • Promotes Restful Sleep: For individuals experiencing sleep difficulties, Dox 10 mg Tablet helps support longer and more restful sleep. Improved sleep quality can help you feel refreshed during the day and support overall mental and physical wellbeing.
     

Directions for Use

  • Dox 10 mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Dox 10 mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Dox 10 mg Tablet Works

Dox 10 mg Tablet contains doxepin. It works by preventing your brain cells from reabsorbing two key natural chemical messengers: serotonin and norepinephrine. By keeping more of these chemicals active in your brain, the medication helps elevate your mood, relieve feelings of anxiety, and calm your nervous system. When taken in much lower doses for sleep issues, the medication acts primarily as a potent blocker of histamine, a natural substance in the body that promotes wakefulness. By blocking these histamine receptors, Dox 10 mg Tablet helps quiet brain activity, making it easier for you to stay asleep throughout the night.
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Alcohol

Unsafe

Dox 10 mg Tablet should not be taken along with alcohol as it can affect you much more and may make you feel more depressed.

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Pregnancy

Caution

Dox 10 mg Tablet is a pregnancy category C drug. It is not known whether it will harm the baby or not. So, it should be only taken when prescribed by a doctor.

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Breast Feeding

Unsafe

Dox 10 mg Tablet is not recommended for breastfeeding women.

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Driving

Unsafe

Dox 10 mg Tablet may impair your concentration and lead to drowsiness, so do not drive after taking Dox 10 mg Tablet .

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Liver

Caution

Inform your doctor before receiving the Dox 10 mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Inform your doctor before receiving the Dox 10 mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Children

Caution

Dox 10 mg Tablet is not recommended for children below the age of 12 years.

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Heart

Consult your doctor

Limited information available for use of Dox 10 mg Tablet in heart patients. Please consult your doctor.

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Geriatrics

Caution

Exercise caution while giving Dox 10 mg Tablet in geriatric patients. Close monitoring of the individual is required.

What if I have taken an overdose of Dox 10 mg Tablet

If you suspect an overdose, seek immediate medical attention or contact your local poison control centre. Symptoms of an overdose can be severe and may include extreme drowsiness, rapid or irregular heartbeat, dilated pupils, confusion, or fainting.

Diet & Lifestyle Advise

  • Manage dry mouth: Drink plenty of water throughout the day, suck on ice chips, or chew sugar-free gum to keep your mouth moist.
  • Prevent constipation: Eat a diet rich in fibre, including whole grains, fruits, and vegetables, and stay physically active if possible.
  • Stand up slowly: To prevent dizziness or fainting, take your time when rising from a lying or sitting position.
  • Keep a consistent sleep schedule: If you are treating sleep issues, go to bed and wake up at the same time every day to reinforce your body's natural sleep cycle.
  • Limit late-day stimulants: Avoid caffeine, chocolate, and heavy meals close to bedtime, as they can interfere with both sleep quality and anxiety management.
     
health query

Have a query?

How Soon It Starts Working

The time required for Dox 10 mg Tablet to start to work: The time required for Dox 10 mg Tablet to show its action is not clinically established. The time for which the effects of Dox 10 mg Tablet last: The duration of action for Dox 10 mg Tablet is not clinically established.

What if you forget to take Dox 10 mg Tablet

If you take this medicine once daily at bedtime and miss a dose, skip the missed dose and take your next dose at the regular time the following night. Do not take a double dose to make up for a missed one. If you take it multiple times a day, take the missed dose as soon as you remember, unless it is almost time for your next dose.

Storage

•Store Dox 10 mg Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Do not drive, operate machinery, or perform dangerous activities until you know how this medication affects your alertness and coordination.
  • Never stop taking this medication suddenly, as doing so can cause unpleasant withdrawal symptoms like nausea, headache, and sleep problems. Your doctor will help you taper off safely.
  • Avoid consuming alcohol while taking this medicine, as it can dangerously increase drowsiness and slow your breathing.
  • Protect your skin from direct sunlight; this medicine can make your skin more sensitive to sunburn. Wear sunscreen and protective clothing when outdoors.
  • Inform your doctor or dentist that you are taking this medication before undergoing any scheduled surgery or dental procedures.
     

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Drug-Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine within 14 days of taking an MAOI, as this can lead to a dangerously high, life-threatening spike in blood pressure.
  • Central Nervous System Depressants: Combining this medication with pain relievers, sleeping pills, muscle relaxers, or other anxiety medicines can cause severe drowsiness and slow your breathing.
  • Anticholinergic Drugs: Taking this with certain allergy medicines or overactive bladder treatments can increase the risk of dry mouth, severe constipation, and difficulty urinating.

Drug-Food Interactions

  • Alcohol: Avoid alcohol completely, as it can worsen side effects like dizziness, drowsiness, and confusion.
  • Grapefruit Juice: Avoid consuming large amounts of grapefruit juice, as it may raise the levels of this medicine in your body and increase the risk of side effects.

Drug-Disease Interactions

  • Glaucoma: Do not take this medicine if you have untreated narrow-angle glaucoma, as it can increase fluid pressure in your eyes.
  • Urinary Retention: Avoid this medication if you have severe trouble emptying your bladder, as it can worsen urinary blockage.
  • Heart Conditions: Use with caution if you have a history of irregular heartbeats or heart disease, as this medication can affect your heart rhythm.

 

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Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

Dox 10 mg Tablet is used to treat depression and anxiety when patients become intolerant to other medicines. In addition, it is also used to treat insomnia (difficulty in sleeping) in some people.
Dox 10 mg Tablet contains Doxepin, a tricyclic antidepressant. It works by increasing the levels of certain brain chemicals involved in regulating mood, helping reduce symptoms of depression and anxiety. When prescribed at low doses for insomnia, it helps improve sleep by promoting longer and better-quality sleep.
Take Dox 10 mg Tablet exactly as prescribed by your doctor. If it is prescribed for insomnia, take it within 30 minutes before bedtime and avoid taking it during the day, as it can cause significant drowsiness. If it is prescribed for depression or anxiety, take it at the same time each day, following your doctor's instructions.
Yes. Some people may experience increased appetite or weight gain while taking Dox 10 mg Tablet , particularly at higher doses used for depression or anxiety. Maintaining a healthy diet and regular physical activity may help. Contact your doctor if you notice significant or persistent weight gain.
If you have allergies to any of its ingredients or are pregnant, you are advised to avoid using Dox 10 mg Tablet . Do not take the Dox 10 mg Tablet if you have glaucoma (increased eye pressure), severe liver or kidney issues, or trouble urinating. Take Dox 10 mg Tablet only as recommended by a doctor and with under medical care if you are pregnant or nursing. If you have taken an MAO inhibitor within the last 15 days, avoid taking Dox 10 mg Tablet .
Yes, Dox 10 mg Tablet can be used to treat insomnia, especially in people who do not fall asleep or have difficulty staying asleep.
No, do not drive while taking Dox 10 mg Tablet , as it may cause drowsiness and impair your concentration. If you feel sleepy or dizzy, avoid driving until you are sure it is safe.
Overdose symptoms of Dox 10 mg Tablet can include irregular heartbeat, feeling agitated or confused, drowsiness, trouble concentrating, vomiting, seizures, muscle stiffness, increase in pupil size, hallucination (seeing or hearing things that aren't there), fever, low body temperature, and even coma (loss of consciousness for some time). If you suspect an overdose, seek immediate medical help from your doctor.
Yes, Dox 10 mg Tablet , like other antidepressants, may increase the risk of suicidal thoughts or behaviours, particularly in children, adolescents, and young adults. This risk is higher when starting the medication or adjusting the dosage. If you notice any changes in your mental health while using Dox 10 mg Tablet , please contact your doctor immediately.
The common side effects of Dox 10 mg Tablet include drowsiness, dry mouth, increased heart rate, constipation, weight gain, difficulty urinating, and a sudden drop in blood pressure upon standing (orthostatic hypotension). Most of these side effects may resolve gradually over time, but if they persist or worsen, please consult your doctor.
No. Dox 10 mg Tablet is generally not considered habit-forming or addictive. However, stopping it suddenly after long-term use may cause withdrawal symptoms. Always consult your doctor before reducing or stopping your medication.
Dry mouth is a common side effect. You can manage it by sipping water throughout the day, sucking on ice chips, or chewing sugar-free gum. If the dryness is severe, painful, or does not go away, talk to your doctor or pharmacist.
No. Avoid drinking alcohol while taking Dox 10 mg Tablet . Alcohol can increase drowsiness, dizziness, impaired coordination, and other side effects, making activities such as driving more dangerous.
No. Do not stop taking Dox 10 mg Tablet suddenly, even if you feel better. Abrupt discontinuation may cause withdrawal symptoms such as nausea, headache, sleep disturbances, irritability, and recurrence or worsening of your symptoms. Your doctor may gradually reduce your dose before stopping treatment. Always consult your doctor before making any changes to your medication.
Yes, many over-the-counter cold, allergy, and cough medicines contain ingredients that can cause severe drowsiness or interact poorly with this medication. Always talk to your doctor or pharmacist before taking any new over-the-counter products.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A682390 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.8133 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 070791S027Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Doxepin Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Doxepin Doxepin. 1969. [Accessed on 22 Mar. 2019]Check here
  6. Anasheh Almasi; Carlos E. Meza. Doxepin. NIH National Library of Medicine, National center for biotechnology information. Statpearls. January 2022. [Accessed on 27th May 2022]Check here

Country of origin

India

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, Riico, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - DOX0182

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