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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Doxcef O Tablet is used to treat bacterial infections of the lungs (pneumonia), sinus (sinusitis), bladder (cystitis), ear infections, etc. It contains Ofloxacin and Cefpodoxime, which kills the bacteria and helps treat and prevent the spread of bacterial infections. Sometimes, it may cause common side effects such as dizziness, pain in the lower legs, neck pain, stomach pain and headache. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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rxMedicinePrescription drug

Whats That

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Synonym :

CEFPODOXIME PROXETIL+OFLOXACIN

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Doxcef O Tablet

Doxcef O Tablet belongs to the group of medicines called broad-spectrum antibiotics, which are used to treat bacterial infections of the lungs (pneumonia), sinus (sinusitis), bladder (cystitis), ear infections, etc. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Doxcef O Tablet does not work against infections caused by the virus, including cold and flu. Using antibiotics when they aren't required can make them not work (develop antibiotic resistance) for future contaminations.

Doxcef O Tablet is a combination of two antibiotic drugs: Ofloxacin and Cefpodoxime. Ofloxacin inhibits DNA gyrase, which is required for DNA replication, transcription and repair. Cefpodoxime works by preventing the formation of bacterial cell covering (cell wall), which is necessary for their survival. Thereby, it kills the bacteria (bactericidal) and helps treat and prevent the spread of bacterial infections. Together, Doxcef O Tablet helps in treating bacterial infections.

Take Doxcef O Tablet with or without food. The dose and duration of Doxcef O Tablet can vary depending on your condition and the severity of the infection. Sometimes, you may experience common side effects such as dizziness, pain in the lower legs, neck pain, stomach pain and headache. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Doxcef O Tablet , please inform your doctor if you have any allergy (against any antibiotic) or kidney or liver problems. Do not take Doxcef O Tablet on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Doxcef O Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Doxcef O Tablet as it may cause increased dizziness. Doxcef O Tablet is not recommended for use in children.

Uses of Doxcef O Tablet

Treatment of Bacterial infections.

Directions for Use

• Take Doxcef O Tablet with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Doxcef O Tablet belongs to the group of medicines called antibiotics, which treat bacterial infections like urinary tract infections, respiratory tract infections, sexually transmitted infections, soft tissue infections, and ear and eye infections. Doxcef O Tablet is a combination of two antibiotic drugs: Ofloxacin and Cefpodoxime. Ofloxacin inhibits DNA gyrase, which is required for DNA replication, transcription and repair. Cefpodoxime inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Doxcef O Tablet helps in treating bacterial infections. Doxcef O Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

How Doxcef O Tablet Works

Doxcef O Tablet is a combination of two antibiotic drugs: Ofloxacin and Cefpodoxime. Ofloxacin inhibits DNA gyrase, which is required for DNA replication, transcription and repair. Cefpodoxime works by preventing the formation of bacterial cell covering (cell wall), which is necessary for their survival. Thereby, it kills the bacteria (bactericidal) and helps treat and prevent the spread of bacterial infections. Together, Doxcef O Tablet helps in treating bacterial infections.

Storage

Keep Doxcef O Tablet out of reach and sight of children.
Side effects of Doxcef O Tablet
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Wear cotton underwear and loose pants to facilitate better airflow.
  • Try meditation and yoga to reduce stress and improve balance hormones.
  • Eat foods like yogurt or kefir to support vaginal health.
  • Gently clean the genital area with soap and lukewarm water.
  • Avoid fragrant soap, bubble baths, and douches; these can also irritate.
  • Tell your doctor about any medications or supplements you’re taking, as they may affect vaginal discharge treatments.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Doxcef O Tablet

Do not take more than the prescribed dose of Doxcef O Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Doxcef O Tablet if you are allergic to any of its contents. Do not take Doxcef O Tablet if you have epilepsy or kidney problems. Maintain a minimum gap of two hours between Doxcef O Tablet and antacid, vitamin and mineral medicines. Consult your doctor before taking Doxcef O Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Doxcef O Tablet as it causes increased dizziness. Doxcef O Tablet is not recommended for use in children.

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
OfloxacinSaquinavir
Critical

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
How does the drug interact with Doxcef O Tablet:
Using Mesoridazine together with Doxcef O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Doxcef O Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Doxcef O Tablet with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Doxcef O Tablet with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Doxcef O Tablet with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Doxcef O Tablet:
Using halofantrine together with Doxcef O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Doxcef O Tablet with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Doxcef O Tablet with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Doxcef O Tablet with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Doxcef O Tablet:
Using bepridil together with Doxcef O Tablet drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Doxcef O Tablet with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
How does the drug interact with Doxcef O Tablet:
The combination of Amiodarone and Doxcef O Tablet may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Doxcef O Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Doxcef O Tablet:
Coadministration of Doxcef O Tablet with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Doxcef O Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Doxcef O Tablet to restore some healthy intestinal bacteria that may have been killed.
  • Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after taking an antibiotic course. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
  • Avoid taking too much calcium-enriched foods and drinks as it might affect the working of Doxcef O Tablet .
  • Avoid intake of alcoholic beverages with Doxcef O Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Doxcef O Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Unsafe

Avoid consuming alcohol while taking Doxcef O Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Doxcef O Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Doxcef O Tablet passes into breastmilk. Consult your doctor before taking Doxcef O Tablet if you are breastfeeding.

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Driving

Caution

Doxcef O Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Doxcef O Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or kidney impairment/kidney disease before taking Doxcef O Tablet .

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Children

Unsafe

Doxcef O Tablet should not be given to children below 18 years.

Have a query?

FAQs

Doxcef O Tablet is used to treat bacterial infections of the lungs (pneumonia), sinus (sinusitis), bladder (cystitis), ear infections, etc.

Doxcef O Tablet is a combination of two antibiotic drugs: Ofloxacin and Cefpodoxime. Ofloxacin inhibits DNA gyrase, which is required to produce DNA replication, transcription, and repair. Cefpodoxime inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Doxcef O Tablet helps in treating bacterial infections.

Avoid taking magnesium and aluminium-containing antacids along with Doxcef O Tablet . Maintain a minimum gap of two hours between both.

Do not take Doxcef O Tablet on your own, as self-medication may lead to antibiotic resistance, which means antibiotics fail to act against specific bacterial infections.

Diarrhoea is the most reported common side effect of Doxcef O Tablet . So, it is advisable to drink lots of water and fluids and eat fibre-rich food if you experience diarrhoea. If you observe blood in stools (tarry stools) or experience excess diarrhoea (vomiting or watery stool), immediately consult your doctor. Do not take anti-diarrheal medicine on your own.

Doxcef O Tablet may cause stomach upset as a side effect. To avoid this, take Doxcef O Tablet , preferably with food. Taking Doxcef O Tablet with food helps in increasing its absorption in the body.

Doxcef O Tablet is a broad-spectrum antibiotic used to treat bacterial infections, and it is not used for viral infections.

No, there is no evidence that Doxcef O Tablet is addictive.

Doxcef O Tablet should be taken for as long as it has been prescribed by the doctor. The duration of treatment will be determined by the doctor based on your medical condition.

Doxcef O Tablet should be taken orally. Swallow it as a whole with water; do not chew, break or crush.

Doxcef O Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

You should not stop taking Doxcef O Tablet even though you feel better as it may cause the infection to recur. Complete the duration of treatment as prescribed by the doctor to get its full benefits.

Take the missed dose of Doxcef O Tablet as soon as you remember. But, if it is time for your next dose take your regular dose and skip the missed dose. Do not take a double dose to make up for the missed dose.

Consult the doctor if you don't feel better even after completing the duration of treatment with Doxcef O Tablet . Also, let your doctor know if any symptoms are worsening while taking Doxcef O Tablet .

The side effects of Doxcef O Tablet include dizziness, pain in the lower legs, loss of appetite, neck pain, headache, and stomach pain. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - DOX0196

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