Doxilyd 50 mg Injection 1's

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MRP ₹1212.5

(Inclusive of all Taxes)

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Written By Lakshmithulasi Yarragunta ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Doxilyd 50 mg Injection is an anti-cancer medicine used to treat cancer. It contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs; this causes double-helix DNA to be uncoiled, destroying DNA and RNA synthesis. Thus, it treats cancer.

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About Doxilyd 50 mg Injection

Doxilyd 50 mg Injection is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Doxilyd 50 mg Injection is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children).

Doxilyd 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.

Doxilyd 50 mg Injection may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Doxilyd 50 mg Injection. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Doxilyd 50 mg Injection should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. Doxilyd 50 mg Injection is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Doxilyd 50 mg Injection

Doxilyd 50 mg Injection is used to treat various types of cancer. The detailed uses of Doxilyd 50 mg Injection are as follows:

Treats solid tumors: Doxilyd 50 mg Injection is used alone or with other medicines to manage bladder, breast, lung, stomach, ovarian, and thyroid cancers, as well as certain soft tissue and bone sarcomas.
Treats blood cancers: Doxilyd 50 mg Injection helps treat Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and certain types of leukemia, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML, ANLL).
Manages childhood cancers: Doxilyd 50 mg Injection is also used to treat neuroblastoma and Wilms ’tumor (a kidney cancer in children) .

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Directions for Use

Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
Doxilyd 50 mg Injection will be administered by the doctor or healthcare professional.
Do not self-administer.

Medicinal Benefits

Doxilyd 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Doxilyd 50 mg Injection is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma.

How Doxilyd 50 mg Injection Works

Doxilyd 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Doxilyd 50 mg Injection out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

Side effects of Doxilyd 50 mg Injection

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Low White Blood Cell Count

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Sudden Feeling Sick

Pink Eye

Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
A warm compress and washing the eyes with water can help with crusting on the eyelids.
Avoid wearing contact lens until you feel better; use spectacles instead.
Do not rub the eyes.
Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.

What if I have taken an overdose of Doxilyd 50 mg Injection

Since Doxilyd 50 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Doxilyd 50 mg Injection may cause sores in the mouth and throat, fever, sore throat, chills, or other signs of infection, unusual bleeding or bruising, black and tarry stools, red blood in stools, and bloody vomit or vomited material that looks like coffee grounds.

Drug Warnings

Doxilyd 50 mg Injection should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. Doxilyd 50 mg Injection is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving Doxilyd 50 mg Injection without a doctor’s advice, as it can cause serious health conditions. Doxilyd 50 mg Injection is known to cause secondary malignancies, tissue necrosis, cardiomyopathy and septic shock in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Drug-Drug Interactions

DoxorubicinZiprasidone

Critical

DoxorubicinMoxifloxacin

Severe

Drug-Drug Interactions

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DoxorubicinZiprasidone

Critical

How does the drug interact with Doxilyd 50 mg Injection:
Coadministration of Doxilyd 50 mg Injection with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Doxilyd 50 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

DoxorubicinMoxifloxacin

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Using Moxifloxacin together with Doxilyd 50 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Doxilyd 50 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or irregular heartbeat, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

DoxorubicinCladribine

Severe

How does the drug interact with Doxilyd 50 mg Injection:
The combined use of cladribine with Doxilyd 50 mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Doxilyd 50 mg Injection with Cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

DoxorubicinCeritinib

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Taking Doxilyd 50 mg Injection with Ceritinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Doxilyd 50 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.

DoxorubicinEtanercept

Severe

How does the drug interact with Doxilyd 50 mg Injection:
When Etanercept is used with Doxilyd 50 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Doxilyd 50 mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without a doctor's advice.

DoxorubicinClozapine

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Taking Doxilyd 50 mg Injection and clozapine may increase the risk of neutropenia.

How to manage the interaction:
Co-administration of Doxilyd 50 mg Injection with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - like a severe infection, fever, diarrhea, sore throat, muscle pain, or difficulty breathing - it's important to call your doctor right away." Do not discontinue any medications without first consulting your doctor.

DoxorubicinEfavirenz

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Taking Efavirenz and Doxilyd 50 mg Injection can increase the risk or severity of irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Doxilyd 50 mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

DoxorubicinInfliximab

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Combining Infliximab with Doxilyd 50 mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Doxilyd 50 mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

DoxorubicinTofacitinib

Severe

How does the drug interact with Doxilyd 50 mg Injection:
Taking Tofacitinib with Doxilyd 50 mg Injection may increase the risk of serious infection.

How to manage the interaction:
Although taking Tofacitinib and Doxilyd 50 mg Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.

DoxorubicinDisopyramide

Severe

How does the drug interact with Doxilyd 50 mg Injection:
The combined use of Doxilyd 50 mg Injection and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Doxilyd 50 mg Injection and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy.
Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.

Pregnancy

Unsafe

Doxilyd 50 mg Injection is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Doxilyd 50 mg Injection. Use reliable methods of birth control while on treatment with Doxilyd 50 mg Injection.

Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Doxilyd 50 mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

Driving

Caution

Doxilyd 50 mg Injection may cause dizziness and tiredness; therefore, avoid driving vehicles or operating machinery until you return to normal.

Liver

Caution

Doxilyd 50 mg Injection should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.

Children

Consult your doctor

Doxilyd 50 mg Injection is used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children). Your doctor may recommend a suitable dosage based on your child's condition.

Heart

Doxilyd 50 mg Injection should be avoided or used with extreme caution in people with heart problems due to its high risk of cardiotoxicity. If necessary, close cardiac monitoring and consideration of safer alternatives are essential.

Geriatrics

Caution

Geriatric patients can receive Doxilyd 50 mg Injection, but with extra caution due to increased risks of heart damage and bone marrow suppression. Close monitoring of cardiac function and organ health is essential throughout treatment.

FAQs

What is the use of Doxilyd 50 mg Injection?

Doxilyd 50 mg Injection is used to treat Breast Cancer.

How does Doxilyd 50 mg Injection work?

Doxilyd 50 mg Injection contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Can Doxilyd 50 mg Injection affect my ability to get pregnant?

Doxilyd 50 mg Injection can disrupt a woman&#039;s natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with Doxilyd 50 mg Injection.

Is Doxilyd 50 mg Injection a vesicant?

Yes, Doxilyd 50 mg Injection is considered a vesicant. This means it may cause tissue blistering and damage if it leaks out of the vein during administration in some individuals. Hence, this medication must be administered by a trained healthcare professional to reduce the risk of this complication.

What are the common side effects of Doxilyd 50 mg Injection?

The common side effects of Doxilyd 50 mg Injection may include nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhoea, and pain at the injection site. Most of these side effects are mild and temporary, and they often resolve on their own over time. However, if you experience persistent, severe, or worsening side effects, it's crucial to consult your doctor.

Can Doxilyd 50 mg Injection be administered by a breastfeeding woman?

It is not recommended for use in breastfeeding women as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before prescribing Doxilyd 50 mg Injection.

What is Doxilyd 50 mg Injection?

Doxilyd 50 mg Injection is an anti-cancer medication used to treat various types of cancer. It belongs to the class of anthracycline topoisomerase inhibitors.

Can I take alcohol while on Doxilyd 50 mg Injection?

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended during the treatment.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Other Info - DOX0089

Keep Refrigerated. Do not freeze.

Author Details

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 22, 2025 | 7:27 AM IST

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