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  1. Home
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  3. Doxinate XT Tablet 15's

Doxinate XT Tablet 15's, Pack of 15
Doxinate XT Tablet 15's, Pack of 15
Doxinate XT Tablet 15's, Pack of 15
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Composition :

DOXYLAMINE SUCCINATE-20MG + L METHYLFOLATE CALCIUM-1MG + METHYLCOBALAMIN-1500MCG + PYRIDOXAL 5 PHOSPHATE-20MG

Manufacturer/Marketer :

Maneesh Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Doxinate XT Tablet

Doxinate XT Tablet used to control nausea and vomiting during pregnancy. It helps treat morning sickness (nauseous feeling during the first trimester) in pregnant women. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the body's natural response to discharge the stomach content forcefully.

Doxinate XT Tablet contains Methylcobalamin, L Methylfolate Calcium, Pyridoxal 5 Phosphate (vitamin B6) and Doxylamine Succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate belongs to the class of antihistamines that work by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body. Thus, it helps treat nausea and vomiting during pregnancy.

Take Doxinate XT Tablet as prescribed. You are advised to take Doxinate XT Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, constipation, dizziness, or blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are allergic to any foods or medicines, please tell your doctor. The Doxinate XT Tablet is usually not taken by breastfeeding mothers as it passes into breast milk. Doxinate XT Tablet should not be given to children as safety and efficacy have not been established. Doxinate XT Tablet may cause dizziness; therefore, drive with caution. Avoid consuming alcohol along with Doxinate XT Tablet as it could lead to increased dizziness. If you are taking MAO inhibitors, inform your doctor, as taking them along with Doxinate XT Tablet may cause unpleasant side effects.

Uses of Doxinate XT Tablet

Treatment of nausea and vomiting in pregnancy

Directions for Use

Swallow it as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Doxinate XT Tablet combines four drugs: Methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. Doxinate XT Tablet relieves nausea and vomiting that occurs in pregnancy due to some hormonal changes. It acts by blocking the activity of some chemicals which make you sick. It will also increase your vitality during pregnancy.

How Doxinate XT Tablet Works

Doxinate XT Tablet contains Methylcobalamin, L Methylfolate Calcium, Pyridoxal 5 Phosphate (vitamin B6) and Doxylamine Succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate belongs to the class of antihistamines that work by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body. Thus, it helps treat nausea and vomiting during pregnancy.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Doxinate XT Tablet

If you accidentally take more medicine than your doctor told you to, or if a child has taken some medicine by mistake, contact your doctor or go to your nearest emergency department immediately. An overdose could cause adverse events. Signs and symptoms of overdose may include restlessness, dryness of mouth, dilated pupils, sleepiness, vertigo, mental confusion and tachycardia. At toxic doses, doxylamine exhibits anticholinergic effects, including seizures, rhabdomyolysis, acute renal failure and death. Consult the doctor even if there are no signs of discomfort.

Drug Warnings

Do not take Doxinate XT Tablet if you are allergic to any of its contents. Tell your doctor if you have asthma, increased eye pressure, narrow-angle glaucoma, stomach ulcer, a blockage in your gut (digestive tract), or liver or kidney problems. Inform your doctor if you are taking medicines for depression, cough or cold medicines, sleeping medicines, or certain pain medicines. Doxinate XT Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Doxinate XT Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Doxinate XT Tablet as it could lead to increased dizziness.

Drug-Drug Interactions

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DoxylamineTranylcypromine
Critical
DoxylaminePotassium citrate
Severe

Drug-Drug Interactions

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DoxylamineTranylcypromine
Critical
How does the drug interact with Doxinate XT Tablet:
Taking Doxinate XT Tablet with tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Doxinate XT Tablet and Tranylcypromine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DoxylaminePotassium citrate
Severe
How does the drug interact with Doxinate XT Tablet:
Taking Doxinate XT Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Potassium citrate and Doxinate XT Tablet, but it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting the doctor.
DoxylamineFentanyl
Severe
How does the drug interact with Doxinate XT Tablet:
Taking Doxinate XT Tablet with Fentanyl together can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Doxinate XT Tablet with Fentanyl can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you feel drowsiness, loss of balance, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Doxinate XT Tablet:
Coadministration of Doxinate XT Tablet with Neomycin can impair the absorption of Doxinate XT Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Doxinate XT Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminChloramphenicol
Moderate
How does the drug interact with Doxinate XT Tablet:
Coadministration of Doxinate XT Tablet with Chloramphenicol can impair absorption and increase the levels of Doxinate XT Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Doxinate XT Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit taking foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Doxinate XT Tablet since it could lead to increased dizziness and drowsiness.

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Pregnancy

Safe

Doxinate XT Tablet is intended for use in pregnant women. However, please consult your doctor if you have any concerns.

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Breast Feeding

Safe if prescribed

Limited data is available. It is safe to take Doxinate XT Tablet in breastfeeding if prescribed by a doctor.

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Driving

Caution

Doxinate XT Tablet may cause dizziness, drowsiness, and blurred vision; hence, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

Limited information is available about using Doxinate XT Tablet in patients with liver disease. If you have liver problems, inform your doctor before taking Doxinate XT Tablet .

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Kidney

Consult your doctor

Limited information is available about using Doxinate XT Tablet in patients with kidney disease. If you have kidney problems, inform your doctor before taking Doxinate XT Tablet .

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Children

Unsafe

Doxinate XT Tablet is not recommended for children below 18 years of age, as the safety and efficacy have not been established.

Have a query?

FAQs

Doxinate XT Tablet is used to treat nausea and vomiting in pregnancy.

Doxinate XT Tablet contains methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.

Never increase your prescribed dose. If you have taken an overdose of this medicine accidentally, seek emergency medical help.

Doxinate XT Tablet may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that helps improve digestion. Limit the intake of alcohol to manage your constipation.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

Country of origin

India

Manufacturer/Marketer address

Plot No. 29-33, Ancillary Industrial Plots, Govandi, Mumbai - 400 043.
Other Info - DOX0486

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 9:31 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.9344.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/209661lbl.pdf
  3. https://www.carexiahealthcare.com/products.html
  4. https://www.drugs.com/mtm/doxylamine.html#interactions
  5. https://www.webmd.com/drugs/2/drug-144683-1914/doxylamine-pyridoxine-vit-b6-oral/doxylamine-pyridoxine-extended-release-oral/details

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