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  3. Doxybuz 100 mg Injection 1's

Doxybuz 100 mg Injection 1's, Pack of 1 INJECTION
Doxybuz 100 mg Injection 1's, Pack of 1 INJECTION
Doxybuz 100 mg Injection 1's, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Doxybuz 100 mg Injection is an antibiotic medicine used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections, and periodontitis. This medicine contains doxycycline which works by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea.
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Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Doxybuz 100 mg Injection

Doxybuz 100 mg Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxybuz 100 mg Injection may also be used to treat or prevent anthrax.

Doxybuz 100 mg Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxybuz 100 mg Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Doxybuz 100 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Doxybuz 100 mg Injection may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Doxybuz 100 mg Injection do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Doxybuz 100 mg Injection if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Doxybuz 100 mg Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Doxybuz 100 mg Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Doxybuz 100 mg Injection belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

How Doxybuz 100 mg Injection Works

Doxybuz 100 mg Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxybuz 100 mg Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Doxybuz 100 mg Injection
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
  • Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
  • Limit alcohol intake and abstain from smoking to promote general wellbeing.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.

What if I have taken an overdose of Doxybuz 100 mg Injection

Doxybuz 100 mg Injection is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose can cause nausea, vomiting, diarrhea, photosensitivity (skin reaction to the sun), indigestion, loss of appetite and mild rash. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

Do not take Doxybuz 100 mg Injection if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Drug-Drug Interactions

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DoxorubicinZiprasidone
Critical
DoxorubicinAmiodarone
Severe

Drug-Drug Interactions

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DoxorubicinZiprasidone
Critical
How does the drug interact with Doxybuz 100 mg Injection:
Coadministration of Doxybuz 100 mg Injection with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Doxybuz 100 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DoxorubicinAmiodarone
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Coadministration of Doxybuz 100 mg Injection with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Doxybuz 100 mg Injection with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
DoxorubicinCeritinib
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Taking Doxybuz 100 mg Injection with Ceritinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Doxybuz 100 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
DoxorubicinHydroxychloroquine
Severe
How does the drug interact with Doxybuz 100 mg Injection:
The combined use of Doxybuz 100 mg Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Doxybuz 100 mg Injection and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DoxorubicinInfliximab
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Combining Infliximab with Doxybuz 100 mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Doxybuz 100 mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DoxorubicinMoxifloxacin
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Using Moxifloxacin together with Doxybuz 100 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Doxybuz 100 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or irregular heartbeat, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DoxorubicinSotalol
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Using Doxybuz 100 mg Injection together with sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Doxybuz 100 mg Injection, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
DoxorubicinBaricitinib
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Using baricitinib together with Doxybuz 100 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Doxybuz 100 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DoxorubicinTofacitinib
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Taking Tofacitinib with Doxybuz 100 mg Injection may increase the risk of serious infection.

How to manage the interaction:
Although taking Tofacitinib and Doxybuz 100 mg Injection together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
DoxorubicinChloroquine
Severe
How does the drug interact with Doxybuz 100 mg Injection:
Using chloroquine together with doxurubicin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Doxybuz 100 mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Doxybuz 100 mg Injection to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Doxybuz 100 mg Injection.
  • Avoid intake of alcoholic beverages with Doxybuz 100 mg Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Doxybuz 100 mg Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Doxybuz 100 mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not known if alcohol affects Doxybuz 100 mg Injection. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Doxybuz 100 mg Injection belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Doxybuz 100 mg Injection in pregnant women. In some cases, taking Doxybuz 100 mg Injection during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Doxybuz 100 mg Injection.

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Breast Feeding

Caution

Doxybuz 100 mg Injection is excreted in the breast milk. However, the extent of absorption of Doxybuz 100 mg Injection by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Doxybuz 100 mg Injection.

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Driving

Caution

It is not known if Doxybuz 100 mg Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Doxybuz 100 mg Injection is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Doxybuz 100 mg Injection is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Doxybuz 100 mg Injection during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

Have a query?

FAQs

Doxybuz 100 mg Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxybuz 100 mg Injection may also be used to treat or prevent anthrax.

Doxybuz 100 mg Injection stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxybuz 100 mg Injection helps treat bacterial infections.

No, Doxybuz 100 mg Injection should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.

If you are taking Doxybuz 100 mg Injection, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Doxybuz 100 mg Injection as they may affect the absorption of Doxybuz 100 mg Injection. Avoid taking dairy products within 2 hours of taking Doxybuz 100 mg Injection as they may also impair the absorption of Doxybuz 100 mg Injection.

Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.

Doxybuz 100 mg Injection may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.

Doxybuz 100 mg Injection may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.

Doxybuz 100 mg Injection does not completely prevent malaria caused by P. falciparum as Doxybuz 100 mg Injection is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Country of origin

INDIA

Manufacturer/Marketer address

Alniche Life Sciences Pvt. Ltd., S-14, 2nd Floor, Janta Market Rajouri Garden, New Delhi – 110 027
Other Info - DOX0286

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.4063.pdf
  2. https://medlineplus.gov/druginfo/meds/a601141.html
  3. https://www.drugs.com/cdi/doxycycline-injection.html

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