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Duodopa 250mg/25mg Tablet is used in the treatment of Parkinson's disease. It contains Levodopa and Carbidopa, which help to control movement. It may cause common side effects such as nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Duodopa 250mg/25mg Tablet
Duodopa 250mg/25mg Tablet is primarily used in the treatment of Parkinson’s disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion, causing stiffness, tremors, difficulty walking, impaired coordination, and impaired balance.
Duodopa 250mg/25mg Tablet contains 'Levodopa' and 'Carbidopa'. Levodopa is converted into dopamine in the brain and helps regulate movement. Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream, allowing more Levodopa to reach the brain.
The most common side effects of Duodopa 250mg/25mg Tablet are nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
If you are known to be allergic to any of the components in Duodopa 250mg/25mg Tablet, please inform your doctor. If you are pregnant or breastfeeding, it is advised to consult your doctor.
Uses of Duodopa 250mg/25mg Tablet
Duodopa 250mg/25mg Tablet is used in the treatment of Parkinson’s disease. The detailed uses of Duodopa 250mg/25mg Tablet are as follows:
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How Duodopa 250mg/25mg Tablet Works
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Diet & Lifestyle Advise
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Therapeutic Class
Alcohol
Unsafe
Avoid consumption of alcohol with Duodopa 250mg/25mg Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty concentrating.
Pregnancy
Caution
Duodopa 250mg/25mg Tablet is a Category B pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.
Breast Feeding
Caution
Duodopa 250mg/25mg Tablet is excreted in human milk, but the effect of Duodopa 250mg/25mg Tablet on an infant is unknown. So, Duodopa 250mg/25mg Tablet is given to a breastfeeding mother only if the doctor thinks the benefits outweigh the risks.
Driving
Unsafe
Duodopa 250mg/25mg Tablet may cause drowsiness and make you fall asleep suddenly. Therefore, avoid driving if you feel drowsy after taking Duodopa 250mg/25mg Tablet.
Liver
Caution
Take Duodopa 250mg/25mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take Duodopa 250mg/25mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Unsafe
Duodopa 250mg/25mg Tablet is not recommended for children as the safety and efficacy were not established.
Duodopa 250mg/25mg Tablet is used in the treatment of Parkinson's disease, with its symptoms including tremors, spasms, muscle stiffness, and poor muscle control.
It is advised to not take Duodopa 250mg/25mg Tablet glaucoma (damage of optic nerve that is essential for good vision) as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Duodopa 250mg/25mg Tablet.
Duodopa 250mg/25mg Tablet is a combination of two medicines, Levodopa and Carbidopa. Levodopa belongs to the class of medications name as central nervous system agents, while Carbidopa comes in the category of decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. While Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can reach to brain.
It is advised not to stop taking Duodopa 250mg/25mg Tablet without consulting your doctor as it may lead to a severe condition called withdrawal-emergent hyperpyrexia with symptoms such as confusion, fever, muscle stiffness, changes in heartbeat and breathing. Therefore, take Duodopa 250mg/25mg Tablet for as long as your doctor has prescribed it and if you experience any of these symptoms while taking Duodopa 250mg/25mg Tablet, please consult your doctor so that the dose may be gradually reduced.
In some cases, prolonged intake of Duodopa 250mg/25mg Tablet may lead to a decrease of Vitamin B12 in the body. So, your doctor might recommend regular tests for the Vitamin B12 while using Duodopa 250mg/25mg Tablet.
The exact effects of birth control pills with Duodopa 250mg/25mg Tablet is still under research. However, it is best to tell your doctor if you are using any type of hormonal contraception. If a person develops diarrhea and vomiting then they need to change their contraception methods like condoms and other contraceptives.
It has been reported that some patients taking Duodopa 250mg/25mg Tablet have experienced stomach upset. To avoid such conditions take Duodopa 250mg/25mg Tablet should be taken with a meal or snack to avoid or lessen the side effects, including diarrhea, nausea, and indigestion. Later the body becomes habitual to medicine so a person can take it with a light meal or on an empty stomach to get better results. Be sure to ask the doctor about the best time to take the medicine.
Drug interactions have been reported when a person takes Methotrexate with Carbidopa. However, clinical research is still going on to know how does Duodopa 250mg/25mg Tablet affects Methotrexate. One should talk to their doctor for more clarification.
Most people do not face any side effects, including jaundice. However, any person who has been taking Duodopa 250mg/25mg Tablet for a prolonged time should consult their doctor immediately if they notice yellowing of skin/eyes or abdominal pain.
Patients with narrow-angle glaucoma should avoid intake of Duodopa 250mg/25mg Tablet. Levodopa may activate a malignant melanoma (skin cancer), so Duodopa 250mg/25mg Tablet should not be used in patients with suspicious, undiagnosed skin lesions or a melanoma history. Duodopa 250mg/25mg Tablet also causes a deficiency of vitamin B12, so patient with low vitamin B12 should not take Duodopa 250mg/25mg Tablet.
Yes, Duodopa 250mg/25mg Tablet can be taken on an empty stomach as it helps maximize its effectiveness. Please consult your doctor if you have concerns regarding it.
Yes, Duodopa 250mg/25mg Tablet may cause dark urine. This is harmless and resolves after stopping Duodopa 250mg/25mg Tablet. Please consult your doctor if you have concerns regarding it.
Duodopa 250mg/25mg Tablet is a precursor of dopamine (chemical messenger in the brain) primarily used in the treatment of Parkinson’s symptoms including tremors, spasms, muscle stiffness, and poor muscle control.
The common side effects of Duodopa 250mg/25mg Tablet include nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled or involuntary muscle movement). Most of these side effects of Duodopa 250mg/25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Duodopa 250mg/25mg Tablet may cause sleepiness or drowsiness in some individuals. You are not recommended to drive or operate heavy machinery if you are not alert. Please consult your doctor if it is bothering you.
Duodopa 250mg/25mg Tablet should be stored in a cool and dry place away from sunlight and kept away from children’s reach. Dispose of the expired medication through a medication take-back program or by talking to your pharmacist.
Duodopa 250mg/25mg Tablet helps control Parkinson's disease but does not cure it. It might take several months for you to notice the benefits of Duodopa 250mg/25mg Tablet; therefore, keep taking the medicine for the prescribed duration.
Avoid exceeding the recommended dose as it can cause unpleasant side effects. If you're not feeling well or have concerns, talk to your doctor. The doctor will adjust your dose or suggest a better treatment plan for you.
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