Buy Duoluton L Tablet online | Uses, Side Effects, Price and substitutes

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Composition:ETHINYLESTRADIOL-0.05MG+LEVONORGESTREL-0.25MG

Prescription Medicine

Duoluton L Tablet is used for contraception and treating dysmenorrhea (irregular and painful periods). It contains Ethinylestradiol and Levonorgestrel, which maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Also, it prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). It may also change the lining of the uterus to prevent the development of a pregnancy. It may cause side effects such as stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Written By Lakshmithulasi Yarragunta , PharmD (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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More about the Product

Composition :

ETHINYLESTRADIOL-0.05MG+LEVONORGESTREL-0.25MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Duoluton L Tablet

Duoluton L Tablet is an oral prescription medication primarily used to prevent pregnancy. It is a combined hormonal pill that helps women manage family planning reliably. Additionally, healthcare providers may prescribe it to regulate menstrual cycles and manage heavy or painful periods.

For maximum effectiveness, you must take this tablet once daily at the exact same time every day without fail. You can take it with or without food, though taking it with your evening meal or at bedtime may help reduce mild stomach upset. Maintaining a consistent routine is crucial to ensuring its protective effects.

While taking Duoluton L Tablet , you may notice mild side effects like temporary nausea, breast tenderness, or light spotting between your periods. These usually resolve as your body adjusts to the hormones. However, you should contact your doctor immediately if you experience severe symptoms, such as sudden chest pain, severe headaches, or swelling and warmth in one of your legs.

Do not take this if you have a history of blood clots, active liver damage, uncontrolled high blood pressure, or breast cancer. It is also not recommended for women over the age of 35 who smoke, as this combination greatly increases the risk of serious cardiovascular complications. Talk to your doctor to ensure this option is safe for your specific medical history.

Certain medications, including some anti-seizure drugs and specific antibiotics, can make Duoluton L Tablet less effective, increasing the risk of unexpected pregnancy. Avoid smoking while using this treatment, as it raises your risk of heart problems and blood clots. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting this treatment.

Uses of Duoluton L Tablet

Duoluton L Tablet is used to treat contraception and dysmenorrhea (irregular menstrual periods). The detailed uses of Duoluton L Tablet are as follows:

Pregnancy Prevention (Contraception): Duoluton L Tablet is highly effective at preventing unwanted pregnancy by stopping the release of an egg from the ovaries, thickening cervical mucus to block sperm, and altering the womb lining.
Irregular Menstrual Cycles: This medication regulates your hormone levels, helping to establish a highly predictable and consistent monthly period cycle.
Painful or Heavy Periods: Duoluton L Tablet lightens blood flow and reduces painful uterine cramping, making your monthly cycles much more manageable.

Key Benefits

Duoluton L Tablet helps provide reliable contraception while supporting better menstrual cycle control and reproductive health. Regulating hormone levels can help improve menstrual symptoms and offer greater predictability in your monthly cycle. Benefits may include:

• Provides effective and reliable pregnancy prevention when used as directed.
• Helps regulate menstrual cycles and improve cycle predictability.
• Reduces menstrual cramps and discomfort during periods.
• Helps decrease heavy menstrual bleeding and associated symptoms.
• May improve acne and other hormone-related skin concerns in some women.
• May help manage symptoms associated with conditions such as endometriosis and provide certain long-term reproductive health benefits.

Side effects of Duoluton L Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Abnormal Bleeding

Vaginal infection and pain

Acne

Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

Inflammation Of Vagina

Inflammation of Vagina needs immediate attention and cannot be ignored.
Get a physical examination and prevent wearing clothes that can hold heat and moisture.
Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
Follow your doctor's instructions, and rest well with proper medication.
Take a balanced diet and get regular screenings to reduce inflammation.

Directions for Use

Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet.
Take one tablet every day at the exact same time. Setting a daily alarm on your phone can help you stay consistent.
You can take this medication with or without food. If you experience mild nausea, taking it after your evening meal or right before bed may help.
Follow the arrows and days printed on the blister pack to keep track of your daily doses.

How Duoluton L Tablet Works

Duoluton L Tablet contains Ethinylestradiol and Levonorgestrel. • Ethinylestradiol: It helps prevent pregnancy by stopping the release of an egg from the ovaries. It also helps regulate the menstrual cycle and reduce irregular bleeding. • Levonorgestrel: It helps prevent pregnancy by thickening the fluid at the entrance of the womb, making it difficult for sperm to reach an egg. It also helps make the lining of the womb less suitable for implantation.

Alcohol

Unsafe

You are recommended not to consume alcohol along with Duoluton L Tablet to avoid unpleasant side effects.

Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

Breast Feeding

Unsafe

Not safe; this Duoluton L Tablet may pass into breast milk. They may harm the baby and also may affect the production of milk. So, this Duoluton L Tablet is unsafe for breastfeeding mothers.

Driving

Caution

Duoluton L Tablet has no or negligible influence on the ability to drive or use machines.

Liver

Caution

Duoluton L Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Duoluton L Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Children

Caution

Duoluton L Tablet is not recommended for children. Safety and efficacy of Duoluton L Tablet are established in women of reproductive age. But sufficient studies have not been performed on women less than 16 years of age. So, take Duoluton L Tablet only when prescribed by a doctor.

Heart

Unsafe

Duoluton L Tablet is not recommended for use in heart patients as it can lead to side effects like heart attack, blood clots, or stroke in some patients.

Geriatrics

Unsafe

Duoluton L Tablet is not recommended for use in elderly patients and postmenopausal women.

What if I have taken an overdose of Duoluton L Tablet

If you accidentally take more than your prescribed dose, seek emergency medical care immediately. While an overdose of this medication is unlikely to be life-threatening, it can cause symptoms such as severe nausea, vomiting, or unexpected vaginal bleeding. Contact a healthcare provider or your local poison control center right away.

Diet & Lifestyle Advise

Do not smoke: Smoking significantly increases your risk of serious cardiovascular complications, including blood clots, heart attacks, and strokes, especially if you are over 35.
Stay active on long journeys: If you are traveling for more than four hours, make sure to stretch your legs, walk around, or perform simple foot exercises to keep blood circulating and prevent blood clots.
Monitor your blood pressure: This medication can sometimes raise blood pressure. Check your blood pressure regularly at home or during routine doctor visits.
Limit alcohol intake: Excessive drinking can place extra strain on your liver, which is responsible for processing this medication.
Maintain a balanced diet: Eating foods rich in calcium and vitamin D can help support bone health, which is important for overall hormonal wellness.

Health Queries

Is duoluton L used to delay menstruation? Why does my vaginal entrance boil on a regular basis in the same spot?

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Duoluton L can be used to delay or regulate menstruation because it contains hormones that control the cycle, but it should be taken only under a doctor?s advice. Recurrent boils at the vaginal entrance are often due to infections like Folliculitis or a blocked gland such as Bartholin cyst. Keep the area clean and dry, avoid tight clothing, and do not squeeze the boil; if it keeps recurring or becomes painful, consult a gynecologist for proper treatment.

I underwent IUI treatment a few days ago in an attempt to become pregnant.My doctor advised me to take duoluton at night every day.I would like to know why this tablet is recommended.Can I become pregnant after using this medication?

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

Duoluton is given after Intrauterine insemination to support the uterine lining and help implantation of a fertilized egg. It improves the hormonal environment needed for early pregnancy but does not itself cause pregnancy?it only supports it if fertilization has already occurred. Continue it as prescribed, and your doctor will confirm pregnancy with a test after the appropriate time.

I started my period early with heavy bleeding. My doctor prescribed Duoluton L Tablet and said my thyroid test is normal. What should I do?

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

You should take Duoluton L Tablet (Ethinylestradiol and Levonorgestrel) exactly as prescribed by your doctor to help control the bleeding and regulate your menstrual cycle. Since your thyroid test is normal, the bleeding is most likely due to a hormonal imbalance. If the bleeding continues or worsens, contact your gynaecologist without delay.

Have a query?

How Soon It Starts Working

The time required for Duoluton L Tablet to start to work: Duoluton L Tablet ideally shows its action within 7 days of consistent use.

The time for which the effects of Duoluton L Tablet last: The effect of Duoluton L Tablet lasts for 7.7 to 15 hours.

What if you forget to take Duoluton L Tablet

If you miss a dose, take it as soon as you remember, even if that means taking two tablets in one day. Continue taking your subsequent tablets at your regular scheduled time. Depending on when and how many tablets you missed, you may need to use a backup barrier method of contraception (such as condoms) for the next 7 days. Please consult the patient leaflet that came with your pack or talk to your doctor or pharmacist for precise guidance based on your specific cycle week.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Inspect the medicine before use: Always check the expiration date and ensure the blister pack is intact before taking your tablet.
Take your tablet at the same time every day: Consistent daily dosing helps maintain reliable contraceptive protection. Consider using an alarm or reminder app to avoid missed doses.
Use backup contraception when needed: If you experience severe vomiting or diarrhea within 3 to 4 hours of taking a tablet, treat it as a missed dose and use a backup contraceptive method, such as condoms, for the next 7 days.
Inform healthcare providers before surgery: Tell your surgeon or doctor if you have a planned surgery or expect prolonged immobility. You may need to stop Duoluton L Tablet several weeks before the procedure to help reduce the risk of blood clots.
Remember the limitations of protection: Duoluton L Tablet helps prevent pregnancy but does not protect against HIV or other sexually transmitted infections. Use condoms if protection against sexually transmitted infections is needed.
Follow the correct starting instructions: Contraceptive protection usually begins immediately if the medicine is started on the first day of your menstrual period. If started on any other day, use a reliable backup contraceptive method for the first 7 days.
Seek advice when changing contraceptive methods: Consult your doctor or pharmacist for guidance when switching from another birth control pill, injection, implant, IUD, or patch to help maintain continuous contraceptive protection.
Use with special care after childbirth or abortion: The appropriate time to start Duoluton L Tablet after childbirth, abortion, or during breastfeeding depends on your individual situation. Follow your healthcare provider’s instructions carefully.

Drug-Drug Interactions

Drug-Drug Interactions

Anti-seizure medicines (e.g., carbamazepine, phenytoin, phenobarbital): These medicines can reduce the effectiveness of Duoluton L Tablet and increase the risk of unintended pregnancy.
Tuberculosis medicines (e.g., rifampin): Taking these alongside Duoluton L Tablet can significantly lower hormone levels in the body, making the contraceptive less reliable.
Herbal supplements (e.g., St. John's Wort): These supplements may speed up the breakdown of hormones in Duoluton L Tablet , increasing the risk of breakthrough bleeding and contraceptive failure.

Drug-Food Interactions

Grapefruit and grapefruit juice: Consuming grapefruit products while taking Duoluton L Tablet may increase hormone levels in the bloodstream and raise the risk of side effects.

Drug-Disease Interactions

Blood clotting disorders: Duoluton L Tablet can significantly increase the risk of dangerous blood clots in people with existing clotting disorders.
Severe liver disease: Do not take Duoluton L Tablet if you have active liver disease or liver tumors, as it may worsen liver function.
Uncontrolled high blood pressure: Duoluton L Tablet may further increase blood pressure and raise the risk of serious complications such as stroke or heart attack.
Migraines with aura: Duoluton L Tablet may increase the risk of stroke in people who experience migraines accompanied by visual disturbances or other neurological symptoms

Ethinylestradiol + LevonorgestrelAcitretin

Critical

Ethinylestradiol + LevonorgestrelEtretinate

Critical

Drug-Drug Interactions

Ethinylestradiol + LevonorgestrelAcitretin

Critical

How does the drug interact with Duoluton L Tablet:
Co-administration of Acitretin with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Acitretin with Ethinylestradiol, Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelEtretinate

Critical

How does the drug interact with Duoluton L Tablet:
Using Etretinate with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Etretinate with Ethinylestradiol, Levonorgestrel can cause an interaction, consult a doctor before taking it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelTranexamic acid

Critical

How does the drug interact with Duoluton L Tablet:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you experience any symptoms like chest tightness, shortness of breath, blood in the urine, blood in the cough, disturbances in eye sight or swelling in the arms or legs, consult a doctor. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelPrimidone

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Primidone together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Primidone, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelTelaprevir

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Telaprevir together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Telaprevir, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelFelbamate

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Felbamate together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Felbamate, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelLetrozole

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Letrozole together may decrease the blood levels of Letrozole.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Letrozole, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelFosamprenavir

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Fosamprenavir together may decrease the blood levels of Fosamprenavir.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Fosamprenavir, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelExemestane

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Exemestane together may decrease the blood levels of Exemestane.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Exemestane, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelEslicarbazepine

Severe

How does the drug interact with Duoluton L Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Eslicarbazepine together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Eslicarbazepine, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Written By

Lakshmithulasi Yarragunta
PharmD (PB)

Reviewed By

Dr Aneela Siddabathuni
MPharma., PhD

Last Updated

Jun 30, 2026 | 6:18 PM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.

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Duoluton L Tablet 21's

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More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About Duoluton L Tablet

Uses of Duoluton L Tablet

Key Benefits

Headache

Stomach Pain

Nausea

Abnormal Bleeding

Vaginal infection and pain

Acne

Inflammation Of Vagina

Directions for Use

How Duoluton L Tablet Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Duoluton L Tablet

Diet & Lifestyle Advise

Health Queries

Is duoluton L used to delay menstruation? Why does my vaginal entrance boil on a regular basis in the same spot?

I underwent IUI treatment a few days ago in an attempt to become pregnant.My doctor advised me to take duoluton at night every day.I would like to know why this tablet is recommended.Can I become pregnant after using this medication?

I started my period early with heavy bleeding. My doctor prescribed Duoluton L Tablet and said my thyroid test is normal. What should I do?

How Soon It Starts Working

What if you forget to take Duoluton L Tablet

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

All Substitutes & Brand Comparisons

X-Out 21 Tablet 21's

Florina-G Tablet 10's

Dear 21 Tablet 21's

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FAQs

What is the use of Duoluton L Tablet ?

Can Duoluton L Tablet cause spotting in between the regular periods?

Can Duoluton L Tablet cause weight gain?

Does Duoluton L Tablet also protect from sexually transmitted disease (STDs) and AIDS?

When will I get my menstrual periods after taking the last pill?

In which conditions should I avoid taking Duoluton L Tablet ?

What if I forget to take Duoluton L Tablet ?

Is Duoluton L Tablet safe for women with a history of breast cancer?

Is Duoluton L Tablet a 21-day pill used for regulating periods?

How and in what dose should I take Duoluton L Tablet ?

Is Duoluton L Tablet safe for smokers?

What if I vomit after taking Duoluton L Tablet ?

What are the common side effects of Duoluton L Tablet ?

Can I take Duoluton L Tablet while I am breastfeeding?

How long does Duoluton L Tablet take to start preventing pregnancy?

Can I take Duoluton L Tablet with other everyday pain relievers?

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