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  3. Duovir-N Tablet 30's

Duovir-N Tablet 30's, Pack of 1 TABLET
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Duovir-N Tablet is used for the treatment of HIV (human immunodeficiency virus) infection. It contains lamivudine, zidovudine, and nevirapine. This medication works by preventing HIV (the virus) from multiplying, thereby reducing the amount of virus in your body and also increasing the CD4 cell count (white blood cells that protect against infection) in your blood. It may cause common side effects such as nausea, vomiting, diarrhoea, headache, heartburn, depression, cough, stuffy nose, joint pain, and insomnia (difficulty falling asleep). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions. It can cause birth defects, so use effective contraception while taking this medicine and for 12 weeks after stopping it.

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Composition :

LAMIVUDINE-150MG + NEVIRAPINE-200MG + ZIDOVUDINE-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duovir-N Tablet

Duovir-N Tablet belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. HIV is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome), making an individual more susceptible to other infections and diseases like cancer.

Duovir-N Tablet is a combination of three medications: lamivudine, zidovudine, and nevirapine. Lamivudine and zidovudine are nucleosidase reverse transcriptase inhibitors that work together to decrease the amount of virus in your body by inhibiting HIV reverse transcription through viral DNA chain termination. Nevirapine is a non-nucleosidase reverse transcriptase inhibitor that works by lowering the amount of HIV in the blood. Duovir-N Tablet  will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.

You should take Duovir-N Tablet at the dose and duration prescribed by your doctor. You may experience common side effects of Duovir-N Tablet , such as nausea, vomiting, diarrhoea, headache, heartburn, depression, cough, stuffy nose, joint pain, and insomnia (difficulty falling asleep). Most of the side effects of Duovir-N Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.

Before taking Duovir-N Tablet , inform your doctor if you are allergic to any of its ingredients. Always keep your doctor informed about any medications you are currently taking to avoid potential side effects or interactions. Let your doctor know if you have severe liver or kidney disease, severe skin reactions, blood-related problems, myopathy (muscle weakness), and lactic acidosis (buildup of lactic acid in the blood). Consult your doctor before taking Duovir-N Tablet if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Duovir-N Tablet , as it may pass into breast milk. Duovir-N Tablet may cause dizziness or sleepiness, so avoid driving or operating machines until you know how it affects you.

Uses of Duovir-N Tablet

Duovir-N Tablet is used in the treatment of HIV (human immunodeficiency virus) infection. The detailed uses of Duovir-N Tablet are as follows:<br/>•Treatment of HIV infection: Duovir-N Tablet helps decrease the amount of virus in the body and delay the progression of HIV infection to AIDS.<br/>•Improves Immune Function: Duovir-N Tablet helps increase the number of immune cells (CD4+ T cells), thereby improving the immune system.<br/>•Prevention of Mother-to-Child Transmission of HIV: Duovir-N Tablet may be prescribed in pregnant women with HIV to reduce the risk of transmitting the virus to the baby during pregnancy.<br/>

Directions for Use

  • Take Duovir-N Tablet with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Duovir-N Tablet belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. It contains lamivudine, zidovudine, and nevirapine. Duovir-N Tablet work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4+ cell (white blood cells that protect against infection) count in your blood. Duovir-N Tablet  will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. Duovir-N Tablet also helps to reduce the risk of transmitting the virus to the baby during pregnancy.

How Duovir-N Tablet Works

Duovir-N Tablet is a combination of three medications: lamivudine, zidovudine, and nevirapine. Lamivudine and zidovudine are nucleosidase reverse transcriptase inhibitors that work together to decrease the amount of virus in your body by inhibiting HIV reverse transcription through viral DNA chain termination. Nevirapine is a non-nucleosidase reverse transcriptase inhibitor that works by lowering the amount of HIV in the blood. Duovir-N Tablet  will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.

Storage

stored at room temperature below 30°C

What if I have taken an overdose of Duovir-N Tablet

Do not take more than the prescribed dose of Duovir-N Tablet as it may lead to an overdose. If you suspect you have taken an overdose or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

Do not take Duovir-N Tablet if you are allergic to any one of its components. Always keep your doctor informed about any medications you are currently taking, including over-the-counter medicines, vitamins, or herbal supplements, to avoid potential side effects or interactions. Inform your doctor before taking Duovir-N Tablet if you have any medical conditions, such as severe liver or kidney disease, severe hepatomegaly (enlarged liver), severe skin reactions, blood-related problems, myopathy (muscle weakness), lactic acidosis (buildup of lactic acid in the blood), and worsening of hepatitis B infection. Duovir-N Tablet may cause birth defects; therefore, use effective contraception while taking Duovir-N Tablet and for 12 weeks after stopping it. Consult your doctor before taking Duovir-N Tablet if you are pregnant or planning to become pregnant. Avoid breastfeeding if you are infected with HIV or while taking Duovir-N Tablet , as it may pass into breast milk and harm the baby. Duovir-N Tablet may cause dizziness or sleepiness, so avoid driving or performing any activities that require concentration until you know how it affects you.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
NevirapineAtazanavir
Critical

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Duovir-N Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Duovir-N Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
NevirapineAtazanavir
Critical
How does the drug interact with Duovir-N Tablet:
When Atazanavir is taken with Duovir-N Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Duovir-N Tablet.

How to manage the interaction:
Taking Duovir-N Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRanolazine
Critical
How does the drug interact with Duovir-N Tablet:
Co-administration of Duovir-N Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Duovir-N Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
LamivudineLomitapide
Severe
How does the drug interact with Duovir-N Tablet:
Taking Duovir-N Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Duovir-N Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
LamivudineTeriflunomide
Severe
How does the drug interact with Duovir-N Tablet:
Teriflunomide can cause Duovir-N Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Duovir-N Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineBexarotene
Severe
How does the drug interact with Duovir-N Tablet:
Taking bexarotene together with Duovir-N Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Duovir-N Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineMipomersen
Severe
How does the drug interact with Duovir-N Tablet:
Taking Duovir-N Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Duovir-N Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
LamivudineZalcitabine
Severe
How does the drug interact with Duovir-N Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Duovir-N Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Duovir-N Tablet:
Combining Duovir-N Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Duovir-N Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Duovir-N Tablet:
Duovir-N Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Duovir-N Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet – Include fruits, vegetables, whole grains, lean proteins, and healthy fats to support your immune system.
  • Stay well-hydrated – Drink plenty of safe, clean water to help with digestion and medication absorption.
  • Avoid raw or undercooked foods – Reduce the risk of foodborne infections by eating properly cooked meals.
  • Limit sugar and processed foods – These can weaken the immune system and cause weight or blood sugar issues.
  • Maintain a healthy weight – Aim for a weight that supports overall health and energy without stressing your body.
  • Exercise regularly – Engage in moderate activity like walking or yoga to boost energy and mood.
  • Take medications as prescribed – Follow your treatment plan strictly, and take medicines with food if recommended.
  • Avoid smoking and alcohol – These can interfere with treatment and weaken your immune system.
  • Practice good hygiene – Wash hands often and handle food safely to prevent infections.
  • Attend regular medical checkups – Keep in touch with your doctor and report any side effects or concerns promptly.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Duovir-N Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Taking Duovir-N Tablet with alcohol may increase the risk of liver damage. So, avoid alcohol consumption while taking Duovir-N Tablet .

bannner image

Pregnancy

Safe

Duovir-N Tablet can be used during pregnancy under the supervision of a doctor. Studies have not shown any defects in the unborn baby, even though Duovir-N Tablet passes through the placenta. Duovir-N Tablet helps reduce the risk of transmitting the virus to the baby during pregnancy.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding if you are infected with HIV or while taking Duovir-N Tablet .

bannner image

Driving

Unsafe

Duovir-N Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.

bannner image

Liver

Caution

Inform your doctor before taking Duovir-N Tablet if you have severe liver disease. Your doctor may advise you not to take Duovir-N Tablet . Inform your doctor immediately if you develop symptoms such as abdominal pain, loss of appetite, dizziness, bruising, irregular heartbeats, yellowing of the eyes or skin, or darkened urine.

bannner image

Kidney

Caution

Inform your doctor before taking Duovir-N Tablet if you have severe kidney disease. Your doctor may need to adjust the dose of Duovir-N Tablet .

bannner image

Children

Unsafe

Duovir-N Tablet should not be used in children weighing less than 35 kg. If their weight is &gt;35, your doctor may prescribe Duovir-N Tablet and adjust the dose.

Have a query?

FAQs

Duovir-N Tablet belongs to a class of medications called antiretrovirals, primarily used to treat HIV (human immunodeficiency virus) infection. It also helps delay the progression of HIV infection to AIDS and reduces the risk of transmitting the virus to the baby during pregnancy.

If you miss a dose of Duovir-N Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Yes, Duovir-N Tablet causes the weakening of bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.

Duovir-N Tablet is a combination of three medications: lamivudine, zidovudine, and nevirapine. Lamivudine and zidovudine are nucleosidase reverse transcriptase inhibitors that work together to decrease the amount of virus in your body by inhibiting HIV reverse transcription through viral DNA chain termination. Nevirapine is a non-nucleosidase reverse transcriptase inhibitor that works by lowering the amount of HIV in the blood. Duovir-N Tablet  will not cure HIV infection or AIDS; however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.

The common side effects of Duovir-N Tablet include nausea, vomiting, diarrhoea, headache, heartburn, depression, cough, stuffy nose, joint pain, and insomnia (difficulty falling asleep). Most of the side effects of Duovir-N Tablet do not require medical attention and typically resolve on their own over time. However, if the side effects persist, contact your doctor.

HIV is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. But with proper medical care, HIV can be controlled. Some people have flu-like symptoms within 2 to 4 weeks after infection (called acute HIV infection). These symptoms may last for a few days or several weeks. Possible symptoms include fever, chills, rash, muscle aches, night sweats, fatigue, sore throat, mouth ulcers, and swollen lymph nodes.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DUO0032

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:44 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/ppa/lamivudine-nevirapine-and-zidovudine.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022061PI.pdf
  3. https://www.rxwiki.com/zidovudine-lamivudine-and-nevirapine
  4. https://medlineplus.gov/druginfo/meds/a601066.html#:~:text=The%20combination%20of%20lamivudine%20and,of%20HIV%20in%20t

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