NEVIRAPINE is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). NEVIRAPINE is combined with other antiretroviral medicines to treat HIV infection.
NEVIRAPINE contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection.
NEVIRAPINE may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. NEVIRAPINE should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.
NEVIRAPINE should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. NEVIRAPINE is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking NEVIRAPINE. NEVIRAPINE should be used in children only if recommended by the doctor.
Human Immunodeficiency Virus (HIV) Infection.
NEVIRAPINE contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. NEVIRAPINE is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV.
NEVIRAPINE should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. This medicine should only be prescribed in patients with CD4+ greater than 250 cells/mm3 (females) and 400 cells/mm3 (males). Inform your doctor about your medical history and the medicines you take to prevent possible interactions. NEVIRAPINE is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, NEVIRAPINE should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking NEVIRAPINE. Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking NEVIRAPINE. NEVIRAPINE should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. NEVIRAPINE treats the infection but does not cure or prevent it.
Drug-Drug Interactions: NEVIRAPINE may interact with contraceptives (ethyl estradiol, norethindrone), immunosuppressants (cyclosporin, sirolimus, tacrolimus), anti-cancer medicine (cyclophosphamide), Antiarrhythmic drugs (Amiodarone, disopyramide), anticonvulsants (carbamazepine, clonazepam), antifungals (itraconazole), antiviral medicine (ritonavir, indinavir, lopinavir).
Drug-Food Interactions: Avoid smoking and alcohol consumption.
Drug-Disease Interactions: Inform your doctor if you have moderate to severe hepatic impairment, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, hepatic fibrosis, and other skin disorders before starting treatment with NEVIRAPINE.
Avoid alcohol consumption while on treatment with NEVIRAPINE. Alcohol intake might increase the risk of stomach or intestine bleeding.
If you are pregnant or suspect you may be pregnant, inform your doctor before taking NEVIRAPINE. Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.
NEVIRAPINE is excreted in milk. If you have HIV or are taking NEVIRAPINE, you should not breastfeed your baby.
Avoid driving vehicles after taking NEVIRAPINE as it may cause fatigue.
NEVIRAPINE can result in serious, sometimes fatal, liver damage. Inform your doctor if you have or have had a liver illness, particularly hepatitis B or C. Your doctor will most likely advise you not to take NEVIRAPINE.
Before using NEVIRAPINE, inform your doctor if you have or have ever had kidney disease, particularly if you are on dialysis treatment.
Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.
HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. NEVIRAPINE helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.