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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Duranzo Tablet is used to relieve pain. It contains Diclofenac and Codeine which work by reducing the production of chemical substances that cause pain and inflammation and preventing pain signals transmission along the nerves to the brain. This medicine may sometimes cause side effects such as heartburn, indigestion, stomach pain, nausea, vomiting, dizziness, drowsiness and loss of appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duranzo Tablet

Duranzo Tablet belongs to the class of medications called ‘analgesics’ used to treat acute or short-term painful conditions in adults. Pain is a widely used term used to describe an unpleasant feeling or discomfort. It ranges from mild to severe. The severity of the pain depends on the underlying condition. It is also classified as acute (short term) and chronic (long term) depending on pain duration. Acute pain, if left untreated, can result in chronic pain in some conditions.

Duranzo Tablet is a combination of two medicines: Diclofenac and Codeine. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandin's production (chemical substances that cause pain and inflammation) at the affected site and reduce pain. Codeine is an opioid medication and works by preventing pain signals transmission along the nerves to the brain.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Duranzo Tablet are heartburn, indigestion, stomach pain, nausea, vomiting, dizziness, drowsiness and loss of appetite. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Duranzo Tablet if you are allergic to any contents of it. Before taking Duranzo Tablet , inform your doctor if you have bleeding or ulcer in the stomach, history of stomach or bowel problems with NSAIDs, blocked intestine, suffered a head injury or increased pressure in the brain, severe breathing problems, severe liver, kidney, heart failure, history of heart attack or stroke, acute alcoholism, diarrhoea due to inflammation of the bowel or poisoning and problems with blood circulation. It is not recommended in children, pregnant women and breastfeeding mothers. It should be used with caution in elderly patients. Avoid consumption of alcohol as it may increase the risk of side-effects. Duranzo Tablet may cause dizziness or drowsiness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Duranzo Tablet

Treatment of Pain relief.

Directions for Use

• Duranzo Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Duranzo Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Duranzo Tablet is used to provide relief from acute painful conditions in adults. It contains diclofenac and codeine. Diclofenac blocks the production of substances that cause pain, swelling and inflammation, whereas codeine blocks the pain signals and reduce pain. This combination medicine is given when a single pain killer is not effective to treat pain. It is usually used for short-term pain relief.

How Duranzo Tablet Works

Duranzo Tablet is a combination of two medicines: Diclofenac and Codeine. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandin's production (chemical substances that cause pain and inflammation) at the affected site and reduce pain. Codeine is an opioid medication and works by preventing pain signals transmission along the nerves to the brain.

Storage

Keep this medicine out of the sight and reach of children.

What if I have taken an overdose of Duranzo Tablet

Take Duranzo Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you feel that you need to take more of Duranzo Tablet tablets to achieve the same pain relief level, inform your doctor immediately. It is a sign of drug tolerance (you do not respond to the drug in the same way as you did initially). In such cases, the doctor may stop the therapy and prescribe another pain killer. Before taking Duranzo Tablet , inform your doctor if you have any bowel disorders such as colitis (inflammation of the intestine), been addicted to opioids, alcohol, prescription or illegal drugs, previously experienced withdrawal symptoms when stopped taking alcohol or drugs, history of alcoholism or drug abuse, kidney or liver problems, porphyria (inherited blood disorder), enlarged prostate, an underactive thyroid, gallstones, bleeding disorders, asthma, seasonal allergies, long-term respiratory infections or illnesses, angina (chest pain), blood clots, low or high blood pressure, high cholesterol, diabetes, systemic lupus erythematosus (a skin disorder), smoking habit and intolerance to some sugars. Duranzo Tablet increases the risk of heart attack or stroke if high doses are used for prolonged periods. So, use it in the dose and duration as prescribed by the doctor. If you notice chest pain, breathing difficulties, weakness or slurry speech, inform your doctor immediately as it can be a sign of problems with heart or blood vessels. Duranzo Tablet is an anti-inflammatory and can mask the symptoms of an infection, so consult your doctor if you feel unwell.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Duranzo Tablet:
Co-administration of Duranzo Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Duranzo Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Duranzo Tablet:
Co-administration of Duranzo Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Duranzo Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Duranzo Tablet:
The combined use of Duranzo Tablet and Indomethacin can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Duranzo Tablet and Indomethacin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Duranzo Tablet:
Taking Duranzo Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Duranzo Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duranzo Tablet:
Concomitant administration of Duranzo Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Duranzo Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
DiclofenacOxaprozin
Severe
How does the drug interact with Duranzo Tablet:
Taking Duranzo Tablet and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of Duranzo Tablet and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Duranzo Tablet:
Taking Duranzo Tablet and piroxicam can increase the risk of side effects such as ulcers, inflammation (redness, swelling), bleeding.

How to manage the interaction:
Co-administration of Duranzo Tablet and Piroxicam can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Duranzo Tablet:
Taking amiloride with Duranzo Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Duranzo Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Duranzo Tablet:
Co-administration of Duranzo Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Duranzo Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Duranzo Tablet:
Taking Duranzo Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Duranzo Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis.  Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Avoid alcohol consumption and quit smoking.

Habit Forming

Yes

Therapeutic Class

ANALGESICS
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Alcohol

Caution

Consumption of alcohol increases the risk of side-effects, such as dizziness, drowsiness, liver damage and bleeding in the stomach.

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Pregnancy

Unsafe

Duranzo Tablet is not recommended during pregnancy as it may cause harmful effects to the unborn baby. The baby may become dependent and show withdrawal symptoms after birth.

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Breast Feeding

Unsafe

Duranzo Tablet may pass into breast milk and cause unwanted effects in the nursing baby. So, it is not prescribed in breastfeeding mothers.

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Driving

Caution

Duranzo Tablet may cause dizziness, drowsiness, confusion or hallucinations, so do not drive or operate heavy machinery if you are not fully alert.

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Liver

Caution

Duranzo Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Duranzo Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Duranzo Tablet is not recommended for children below 12 years of age.

Have a query?

FAQs

Duranzo Tablet is used to treat short-term pain.

Duranzo Tablet is a combination of two medicines: Diclofenac and Codeine. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing the production of chemical substances that cause pain and inflammation. Codeine is an opioid medication and works by preventing pain signals transmission along the nerves to the brain.

The common side-effects of Duranzo Tablet are heartburn, indigestion, stomach pain, nausea, vomiting, dizziness, drowsiness and loss of appetite. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is recommended not to take other antidepressants, especially monoamine oxidase inhibitors (MAOI) such as phenelzine and isocarboxazid while using Duranzo Tablet . It may lead to unwanted effects. The doctor may advise you to wait for at least 14 days after discontinuing MAOI if you have been prescribed Duranzo Tablet .

Duranzo Tablet is probably safe and well-tolerated in diabetic patients when taken at recommended doses. However, higher doses or prolonged use may affect sugar levels and cause unwanted effects. So, let your doctor know that you have diabetes before taking Duranzo Tablet .

No, consult a doctor before taking Duranzo Tablet for any condition. It is not advised to use Duranzo Tablet without a doctor's recommendation.

Duranzo Tablet is usually prescribed for a short period. You can stop taking Duranzo Tablet once you have completed the prescribed duration of treatment. However, if you notice any unusual symptoms, stop taking Duranzo Tablet and consult the doctor.

No, it's not recommended. Duranzo Tablet contains diclofenac and codeine, which may interact with cold medications like pain relievers, NSAIDs, or decongestants. This could lead to unwanted side effects and complications. Always consult your doctor before combining Duranzo Tablet with cold medications to ensure your safety.

When using Duranzo Tablet with other pain relievers, be cautious. Combining it with NSAIDs like aspirin and ibuprofen may increase the risk of stomach pain and bleeding. Also, avoid mixing with opioids or sedatives, as it may cause excessive drowsiness and breathing problems. Always consult your doctor before combining medications to ensure safety.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - DUR0130

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