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compositionComposition:LETROZOLE-2.5MG
prescription
Prescription Medicine
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E-Ova L 2.5Mg Capsule is used to treat breast cancer in women who have gone through menopause (cessation of menses periods). It contains Letrozole, which prevents the growth of cancer cells. Thereby, it helps in preventing or stopping the growth of spreading the tumours (cancer cells) to other body parts. It may cause certain common side effects such as hypercholesterolemia (increased cholesterol levels), tiredness, weakness, increased sweating, feeling unwell, pain in joints, and hot flushes (feeling of warmth). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LETROZOLE-2.5MG

Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About E-Ova L 2.5Mg Capsule

E-Ova L 2.5Mg Capsule is a prescription oral tablet used primarily to treat certain types of breast cancer in women who have already gone through menopause. It is specifically prescribed for hormone-receptor-positive breast cancers, which rely on hormones to grow. By lowering hormone levels in the body, this medicine helps slow down or stop the growth of cancer cells.

For this medication to work effectively, you must take it consistently at the same time every day. You can take this tablet with or without food, as eating does not affect how the medicine is absorbed. Combining this treatment with a balanced diet and regular physical activity can help support your body and manage potential side effects.

While taking E-Ova L 2.5Mg Capsule, you may experience mild side effects such as hot flashes, joint pain, or feeling unusually tired. While these are common, you should contact your doctor right away if you experience serious symptoms like severe chest pain, sudden shortness of breath, or signs of liver damage such as yellowing of your eyes or skin.

Do not take this if you are pregnant, breastfeeding, or have not yet gone through menopause. It is important to talk to your doctor before starting this medicine if you have a history of bone loss, high cholesterol, liver problems, or severe kidney disease.

This medicine can interact with other treatments, especially therapies that contain oestrogen, such as birth control pills or hormone replacement therapy, which can make this medication less effective. Older adults can safely take this medication, but your doctor will monitor your health closely during treatment to ensure your safety.
 

Uses of E-Ova L 2.5Mg Capsule

E-Ova L 2.5Mg Capsule is used to treat certain types of breast cancer in women who have already gone through menopause. The detailed uses of E-Ova L 2.5Mg Capsule are as follows:

  • Hormone-Receptor-Positive Early Breast Cancer: Used as an additional treatment in postmenopausal women who have already undergone surgery or radiation to lower the risk of the cancer returning.
  • Advanced Breast Cancer: Used as a primary treatment for postmenopausal women when the breast cancer has spread to other parts of the body.
  • Extended Breast Cancer Therapy: Prescribed for women who have already completed several years of initial cancer therapies to provide continued protection against recurrence.

Key Benefits

E-Ova L 2.5Mg Capsule helps manage hormone-sensitive breast cancer by lowering oestrogen levels in the body, reducing the signals that encourage cancer cells to grow. By supporting both treatment and long-term disease control, this medicine offers several key benefits:

  • Helps Reduce the Risk of Cancer Recurrence: For patients who have completed initial breast cancer treatment, E-Ova L 2.5Mg Capsule helps lower the risk of the cancer returning. By reducing oestrogen levels, it helps limit the growth of hormone-sensitive cancer cells and supports long-term treatment outcomes.
  • Supports Control of Advanced Breast Cancer: In patients with advanced breast cancer, this medicine can help slow tumour growth or reduce tumour size. This may help control disease progression and support ongoing cancer management.
  • Helps Maintain Quality of Life: By helping manage cancer growth and related symptoms, E-Ova L 2.5Mg Capsule can support greater physical comfort and daily functioning. This may allow patients to continue their usual activities with improved confidence and well-being during treatment.
     

Directions for Use

To get the most benefit from this medicine, follow these instructions carefully:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • You can take this medication with or without food.
  • Try to take your dose at the same time every day to keep a steady amount of the medicine in your body.
  • Always follow your doctor's exact instructions regarding how long you should continue taking this medicine, as cancer therapies are often long-term treatments.
     

How E-Ova L 2.5Mg Capsule Works

Many breast cancers in postmenopausal women are fuelled by the hormone oestrogen. Even after menopause, the body continues to produce small amounts of oestrogen by converting other hormones using a natural enzyme called aromatase. E-Ova L 2.5Mg Capsule works by blocking this aromatase enzyme. By stopping this conversion process, the medication significantly lowers the amount of oestrogen circulating in your body. Without a sufficient supply of oestrogen, hormone-receptor-positive breast cancer cells lose their primary source of growth, causing them to shrink or stop multiplying.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking E-Ova L 2.5Mg Capsule to avoid unpleasant side effects. Alcohol intake, along with E-Ova L 2.5Mg Capsule, may cause increased drowsiness.

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Pregnancy

Unsafe

E-Ova L 2.5Mg Capsule is pregnancy category D medicine so, should not be taken during pregnancy.

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Breast Feeding

Unsafe

E-Ova L 2.5Mg Capsule should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby.

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Driving

Unsafe

E-Ova L 2.5Mg Capsule may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Safe if prescribed

It is safe to take E-Ova L 2.5Mg Capsule if prescribed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

It is safe to take E-Ova L 2.5Mg Capsule if prescribed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

E-Ova L 2.5Mg Capsule should not be used by children, as the efficacy and safety have not been established.

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Heart

Unsafe

E-Ova L 2.5Mg Capsule is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Caution should be exercised while taking E-Ova L 2.5Mg Capsule in geriatric patients, as it can lead to adverse effects.

What if I have taken an overdose of E-Ova L 2.5Mg Capsule

Do not take more than the prescribed dose of E-Ova L 2.5Mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Protect your bones: Because this medicine lowers oestrogen, it can reduce bone density. Ask your doctor about taking calcium and vitamin D supplements to help keep your bones strong.
  • Stay active: Engage in regular, weight-bearing exercises like walking or light strength training to maintain bone strength and reduce joint stiffness.
  • Monitor your cholesterol: Eat a heart-healthy diet rich in fibre, vegetables, and lean proteins, as this medicine can sometimes increase blood cholesterol levels.
  • Stay hydrated: Drink plenty of water throughout the day, which can help manage fatigue and reduce the intensity of hot flashes.
     
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How Soon It Starts Working

The time required for E-Ova L 2.5Mg Capsule to start to work: E-Ova L 2.5Mg Capsule ideally shows its action within 2 to 6 weeks after administration. The time for which the effects of E-Ova L 2.5Mg Capsule last: The effect of E-Ova L 2.5Mg Capsule lasts for 2 days.

What if you forget to take E-Ova L 2.5Mg Capsule

If you miss a dose of E-Ova L 2.5Mg Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store E-Ova L 2.5Mg Capsule at room temperature, between 20°C and 25°C (68°F to 77°F) •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Inspect your tablet before taking it; do not use it if the packaging is damaged or the tablet looks broken.
  • Do not take this medication if you are pregnant, as it can cause serious harm to an unborn baby. Use reliable, non-hormonal birth control during treatment.
  • This medication can cause dizziness or fatigue; avoid driving or operating heavy machinery until you know how it affects you.
  • Be sure to attend all scheduled medical appointments so your doctor can monitor your bone density and cholesterol levels.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Oestrogen-containing therapies: Medicines like birth control pills, oestrogen creams, or hormone replacement therapies can reverse the effects of E-Ova L 2.5Mg Capsule and should be avoided.
  • Tamoxifen: Taking this medication alongside tamoxifen can lower the level of E-Ova L 2.5Mg Capsule in your body, making it less effective.

Drug-Disease Interactions

  • Osteoporosis: This medicine lowers oestrogen levels, which can accelerate bone thinning and increase your risk of fractures.
  • Liver Disease: If you have moderate to severe liver damage, your body may process this medication more slowly, requiring closer monitoring by your doctor.

 

LetrozoleDiethylstilbestrol
Severe
LetrozoleCitalopram
Severe

Drug-Drug Interactions

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LetrozoleDiethylstilbestrol
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
Co-administration of E-Ova L 2.5 Capsule may have an effect when used with Diethylstilbestrol, making it less effective in treating your disease.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and diethylstilbestrol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleCitalopram
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
Co-administration of E-Ova L 2.5 Capsule and Citalopram may raise the risk of a serious irregular heartbeat.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and Citalopram together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleDesogestrel
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
Co-administration of Desogestrel together with E-Ova L 2.5 Capsule may decrease the effects of E-Ova L 2.5 Capsule.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and Desogestrel together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any medications.
LetrozoleConjugated Estrogens
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
Coadministration of Conjugated estrogens with E-Ova L 2.5 Capsule may reduce the effect of E-Ova L 2.5 Capsule.

How to manage the interaction:
Although taking Conjugated estrogen and E-Ova L 2.5 Capsule together can result in an interaction, it can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
LetrozoleEstramustine
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
when taken together E-Ova L 2.5 Capsule's function could be blocked by estramustine, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and estramustine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstrone
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
When taken together E-Ova L 2.5 Capsule's function could be blocked by estrone, which would reduce its ability to effectively treat your illness.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and estrone together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleEstradiol
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
E-Ova L 2.5 Capsule may have a negative effect when used with Estradiol, making it less effective in treating your disease.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and estradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LetrozoleThalidomide
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
Coadministration of thalidomide and E-Ova L 2.5 Capsule may increase the risk of blood clots.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, consult a doctor. Do not discontinue any medications without a doctor's advice.
LetrozoleEthinylestradiol
Severe
How does the drug interact with E-Ova L 2.5 Capsule:
When taken together ethinyl estradiol may interfere with E-Ova L 2.5 Capsule's activity and make it less effective in treating the condition.

How to manage the interaction:
Although taking E-Ova L 2.5 Capsule and ethinylestradiol together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

E-Ova L 2.5Mg Capsule is an anti-cancer medicine used to treat hormone receptor-positive breast cancer, particularly in women who have gone through menopause. It helps slow or stop the growth of cancer cells by reducing estrogen production in the body.
E-Ova L 2.5Mg Capsule works by blocking the aromatase enzyme, which is involved in the production of estrogens. The cancer cells require estrogen for their growth, so by blocking the enzyme E-Ova L 2.5Mg Capsule prevents the growth of cancer cells. Thereby, E-Ova L 2.5Mg Capsule helps in slowing down or stopping the growth and/or spreading the tumours to other body parts.
E-Ova L 2.5Mg Capsule causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.
High blood pressure could be a side-effect of E-Ova L 2.5Mg Capsule. Regularly monitor blood pressure levels while taking E-Ova L 2.5Mg Capsule. Consult your doctor if you regularly notice high blood pressure levels.
Do not stop taking E-Ova L 2.5Mg Capsule on your own. You are advised to take E-Ova L 2.5Mg Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking E-Ova L 2.5Mg Capsule.
E-Ova L 2.5Mg Capsule may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking E-Ova L 2.5Mg Capsule.
Some people may experience weight changes while taking E-Ova L 2.5Mg Capsule. Weight gain may occur due to changes in metabolism, appetite, or reduced physical activity. Maintaining a balanced diet and regular exercise may help manage weight. Consult your doctor if you notice significant weight changes.
E-Ova L 2.5Mg Capsule should be swallowed as a whole with water; do not crush or chew it.
E-Ova L 2.5Mg Capsule can be taken with or without food.
E-Ova L 2.5Mg Capsule may cause high blood pressure. Therefore, irbesartan should be taken with E-Ova L 2.5Mg Capsule only if prescribed by the doctor. Regularly monitor blood pressure levels while taking E-Ova L 2.5Mg Capsule.
E-Ova L 2.5Mg Capsule may cause eye problems like blurred vision and cataracts. Consult the doctor if you experience blurred vision or eye irritation.
E-Ova L 2.5Mg Capsule may cause hot flushes leading to sweating. These symptoms usually improve during the first few months. However, if the symptoms persist or worsen, consult the doctor.
Serious side effects of E-Ova L 2.5Mg Capsule are difficulty breathing, chest pain, fainting, rapid heart rate, formation of blood clots (bluish skin discolouration, or sudden arm, leg or foot pain) and rupture of a tendon. These side effects are rare and may not occur in everyone taking E-Ova L 2.5Mg Capsule.
Letrozole may induce ovulation in anovulatory infertility patients and augment follicles for ovulatory women. However, it is an off-label use. Talk to the doctor if you have any concerns.
E-Ova L 2.5Mg Capsule is not recommended for use during pregnancy or while breastfeeding.
The time required for E-Ova L 2.5Mg Capsule to show its effects depends upon your condition and severity. Consult the doctor if you have any concerns.
If you miss a dose of E-Ova L 2.5Mg Capsule take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
E-Ova L 2.5Mg Capsule may interact with antidepressants (citalopram, escitalopram) and anticancer medicines (tamoxifen). Let the doctor know if you are taking these medicines.
Store E-Ova L 2.5Mg Capsule at room temperature, in a dry place. Keep out of sight and reach of children.
No, this medication is designed only for women who have fully gone through menopause. If your ovaries are still producing oestrogen, this medicine will not work as intended. Talk to your doctor if you are unsure of your menopausal status.
The duration of treatment varies depending on your specific diagnosis. It is commonly prescribed for 5 to 10 years to prevent cancer recurrence. Always follow your doctor's recommendations.
Moderate alcohol consumption is generally safe, but excessive drinking can worsen side effects like hot flashes, fatigue, and bone thinning. Discuss your alcohol intake with your doctor.
Some patients experience mild hair thinning or changes in hair texture due to lowered oestrogen levels. If this becomes severe or distressing, talk to your doctor.
Mild joint stiffness is common, but severe pain should be evaluated. Do not start taking over-the-counter pain relievers without consulting your doctor first, as they can recommend the safest option for you.
You can take this medicine at either time, but it is best to take it at the same time every day. If you find it makes you feel tired, taking it before bed may help. Consult your pharmacist for personalised advice.
Yes, your doctor will likely order periodic blood tests to monitor your cholesterol levels and liver function, as well as bone density scans to protect your bone health. Talk to your doctor to understand your monitoring schedule.

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Country of origin

India

Manufacturer/Marketer address

A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070
Other Info - EOV0006
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