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compositionComposition:EDARAVONE-1500MG
prescription
Prescription Medicine
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Edavone 1500mg Injection is used to treat amyotrophic lateral sclerosis (nervous system disease). It contains Edaravone which keeps nerve cells healthy and slows down the worsening of the disease. In some cases, this medicine may cause side effects such as difficulty walking, bruising and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EDARAVONE-1500MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Edavone 1500mg Injection

Edavone 1500mg Injection is a prescription injection used to treat amyotrophic lateral sclerosis (ALS), which is a progressive neurological disease. This medicine is specifically designed to help slow down the decline in daily physical functioning that patients experience over time. By targeting oxidative stress in the nervous system, it helps protect vital nerve cells from rapid damage.

This medicine is typically given in regular, repeating treatment cycles that require daily clinic visits followed by a drug-free recovery period. Keeping all of your scheduled injection appointments is crucial to ensuring the medication works effectively. Adopting a nutrient-rich, high-calorie diet and participating in physical therapy can also support your muscle strength and overall health during your treatment.

While using Edavone 1500mg Injection, some patients may experience mild side effects like bruising at the injection site, headaches, or a temporary change in their walking balance. However, you should contact your doctor immediately if you notice any signs of a severe allergic reaction, such as swelling of the lips, face, or throat, hives, or unexpected trouble breathing.

Before beginning your therapy, it is important to talk to your doctor if you have asthma or a history of sulphite allergies, as this injection contains ingredients that can trigger severe allergic reactions. Do not take this medicine if you have previously had a severe allergic reaction to any of its ingredients.

Let your healthcare team know about all other prescription medications, over-the-counter drugs, or herbal supplements you use, because mixing certain substances can increase the strain on your kidneys. If you are pregnant, planning to breastfeed, or an older adult, consult your doctor or pharmacist to discuss your specific safety plan.

Uses of Edavone 1500mg Injection

Edavone 1500mg Injection is used to treat amyotrophic lateral sclerosis (ALS). The detailed uses of Edavone 1500mg Injection are as follows:

  • Amyotrophic Lateral Sclerosis (ALS): Edavone 1500mg Injection is used to slow the decline of physical function in patients diagnosed with ALS, helping them maintain their muscle control and daily independence for a longer period.
  • Stroke recovery: In specific clinical situations and regions, this injection is used in the early hours of an acute ischaemic stroke to help protect brain cells from damage caused by a lack of blood flow.

Key Benefits

The primary benefit of Edavone 1500mg Injection is its ability to help preserve daily physical abilities in people living with ALS. By slowing the progression of the disease, it can make a meaningful difference in how well you manage daily tasks over time.

  • Slowing disease progression: It helps delay the decline in functional abilities, such as speaking, swallowing, writing, and walking.
    Protecting nerve cells: It acts as a shield for motor neurones, reducing the cellular damage that contributes to the worsening of ALS symptoms.
  • Supporting independence: By preserving muscle function for longer, it helps patients maintain their quality of life and manage personal care tasks.

Directions for Use

  • Follow your doctor's recommendations on the dosage and timing of this medication to achieve optimal results.
  • Edavone 1500mg Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Edavone 1500mg Injection Works

To understand how Edavone 1500mg Injection works, it helps to understand a process called oxidative stress. In a healthy body, cells constantly produce waste products called free radicals. Usually, the body clears these out. However, in people with ALS, these free radicals build up and cause oxidative stress, which damages and eventually kills the motor neurones, the nerve cells that control muscle movement. Edavone 1500mg Injection contains edaravone, which works as a protective agent by searching for and neutralising these harmful free radicals in the nervous system. By clearing these molecules away, the medicine helps prevent them from damaging the delicate structures of your nerve cells. While it cannot repair nerves that are already damaged, this protective action slows down the rate of new damage, helping to preserve your remaining muscle control.
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Alcohol

Caution

It is unknown whether it is safe to consume alcohol while taking Edavone 1500mg Injection or not. It is better to ask your doctor.

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Pregnancy

Caution

Women who are pregnant should ask their doctor before taking Edavone 1500mg Injection as it is not known whether the drug affects the baby or not.

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Breast Feeding

Caution

Women who are breastfeeding should ask their doctor before taking Edavone 1500mg Injection as it is not known whether the drug affects the nourishing baby or not.

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Driving

Unsafe

Persons dealing with ASL face difficulty in driving with disease progression. Thus one should avoid driving while taking Edavone 1500mg Injection.

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Liver

Caution

Edavone 1500mg Injection is safe to be injected in persons with mild liver disease, usually, but caution is advice in patients with severe liver disease and should be used only if prescribed by a doctor.

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Kidney

Caution

Edavone 1500mg Injection should be used with caution in patients with severe renal function disorder and should be used only if prescribed by a doctor.

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Children

Caution

Safety and efficacy of Edavone 1500mg Injection in children have not been established so better to consult with the doctor.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Edavone 1500mg Injection. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Edavone 1500mg Injection in elderly patients. Please consult your doctor.

What if I have taken an overdose of Edavone 1500mg Injection

Since this medicine is prepared and given by professional healthcare providers, an overdose is highly unlikely. However, if you suspect you have received too much of this medication or experience severe symptoms like extreme dizziness or breathing problems during or after an infusion, seek immediate medical attention or contact emergency services.

Diet & Lifestyle Advise

  • Focus on calorie-dense nutrition: ALS can increase your body's energy demands. Work with a dietitian to plan meals that are rich in nutrients and easy to chew and swallow safely.
  • Stay hydrated: Adequate fluid intake is essential for general nerve and muscle function. If swallowing liquids is difficult, talk to your doctor about safe ways to stay hydrated.
  • Incorporate physical and occupational therapy: Regular, gentle exercises prescribed by a physical therapist can help maintain muscle strength and flexibility without causing excessive fatigue.
  • Monitor injection sites: Since this medication is given through an IV, regularly check the skin around your injection site for signs of infection, such as increased warmth, redness, swelling, or pain, and report them to your care team.
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How Soon It Starts Working

The time required for Edavone 1500mg Injection to start to work: The time required for Edavone 1500mg Injection to show its action is not clinically established. The time for which the effects of Edavone 1500mg Injection last: The duration of action for Edavone 1500mg Injection is not clinically established.

What if you forget to take Edavone 1500mg Injection

Because this medicine is given on a strict cyclical schedule by a healthcare professional, missing a dose can disrupt your treatment plan. If you miss an appointment or a scheduled infusion, contact your healthcare provider or clinic immediately to reschedule and find out how to adjust your treatment calendar. Do not double the next dose to make up for a missed one.

Storage

• Store the injection vials or bags at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original packaging to protect it from light.

Drug Warnings

  • Inspect the solution before use: Always check the medicine bag or vial before infusion. The liquid should be clear and colourless. If it is discoloured, cloudy, or has visible particles, do not use it.
  • Report sulphite allergies immediately: This medicine contains sodium bisulphite, which can cause life-threatening allergic reactions in people with asthma. Ensure your medical team knows your complete allergy history before the first dose.
  • Rotate infusion sites: If you receive infusions through a peripheral IV, ask your healthcare provider to rotate the injection sites to protect your veins and prevent local skin irritation.
  • Watch for delayed allergic reactions: Allergic reactions can occur even after the infusion is finished. Keep a close eye on how you feel for several hours after each session.
  • Keep a detailed treatment log: Track your infusion dates and any side effects you experience, and share this log with your doctor at every visit.

verifiedApollotooltip
  • Certain antibiotics (like aminoglycosides): Combining these with Edavone 1500mg Injection may increase the risk of kidney damage. Talk to your doctor if you are being treated for an infection.

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verifiedApollotooltip

No clinically significant food interactions are known with Edavone 1500mg Injection when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Edavone 1500mg Injection is administered as an intravenous (IV) infusion directly into a vein by a trained healthcare professional. Each infusion usually takes about 60 minutes and is typically given in a hospital, infusion clinic, or, in some cases, at home under appropriate medical supervision if your healthcare provider considers it suitable.
Use Edavone 1500mg Injection with caution if you have asthma. It contains sulfites (such as sodium bisulfite), which can trigger serious allergic reactions or asthma attacks in susceptible individuals. Tell your doctor if you have asthma or a history of sulfite sensitivity before starting treatment so they can determine whether this medicine is appropriate for you.
No. Edavone 1500mg Injection does not cure amyotrophic lateral sclerosis (ALS). It helps slow the progression of the disease and may help preserve physical and functional abilities for longer, but it does not reverse or cure the underlying condition. Continue treatment exactly as prescribed by your doctor.
The medication is usually given in cycles. A common schedule involves daily infusions for 14 days, followed by 14 days off. Later cycles may consist of infusions on 10 out of 14 days, followed by another 14-day break. Your specific schedule may vary, so talk to your doctor for exact instructions.
Because this medication is injected directly into a vein, it does not interact with food in your digestive system. You do not need to change your eating schedule around your infusions, though maintaining a healthy diet is important for managing ALS. Talk to your doctor or pharmacist for personalised nutritional advice.
Contact your healthcare provider or infusion clinic immediately to reschedule. Keeping a consistent schedule is very important for the treatment to be effective. Do not try to make up for it yourself; talk to your doctor to adjust your treatment calendar safely.
Some patients experience dizziness or walking difficulties after their infusion. It is highly recommended to have someone drive you to and from your appointments, especially during your first few treatment cycles, until you know how the medicine affects you. Talk to your doctor about whether it is safe for you to drive.
There is limited research on the safety of this injection in pregnant women. If you are pregnant, planning to become pregnant, or breastfeeding, you must carefully discuss the potential benefits and risks with your healthcare team. Talk to your doctor before starting this medication.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Edaravone Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 209176Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. R Bhandari, A Kuhad. Edaravone: a new hope for deadly amyotrophic lateral sclerosis. NIH National Library of medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in June 2018] [Accessed on 19th May 2022]Check here
  4. Martin Paspe Cruz. Edaravone (Radicava). NIH National Library of medicine. National Center for Biotechnology Information. PMC PubMed Central. January 2018. [Accessed on 19th May 2022]Check here
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 22 Mar. 2019]Check here
  6. Edaravone (Radicava ) [Prescribing Information]. 2022. [Accessed on 03 Feb. 2024]Check here
  7. Mitsubishi Tanabe Pharma Corporation. Drug and Health Product Register (HRES). [Revised in October 2018] [Accessed on 19th May 2022] pm/00047612.PDFCheck here

Country of origin

India
Other Info - ED74949
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