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  3. Elspa-DM Tablet

Elspa-DM Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Elspa-DM Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. It contains Drotaverine and Mefenamic acid, which works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Also, it blocks the effect of chemical messengers that cause pain and inflammation. In some cases, it may cause common side effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DROTAVERINE-80MG + MEFENAMIC ACID-250MG

Manufacturer/Marketer :

Estrellas Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Elspa-DM Tablet

Elspa-DM Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Elspa-DM Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Elspa-DM Tablet helps in relieving pain.

You are advised to take Elspa-DM Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Elspa-DM Tablet may cause dizziness, so drive with caution. Elspa-DM Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Elspa-DM Tablet

Elspa-DM Tablet is used in pain management treatments. The detailed uses of Elspa-DM Tablet are as follows:

  • Relief from Menstrual Cramps: Elspa-DM Tablet is frequently used to reduce extreme menstrual pain, which eases period discomfort and cramping.
  • Abdominal Pain Treatment: It can help relieve muscle spasms in the gastrointestinal tract and effectively helps to manage abdominal pain due to various conditions.
  • Postoperative Pain Management: Elspa-DM Tablet is occasionally recommended to help manage pain after surgery, especially in cases when muscle spasms are present.
  • Improving Gastrointestinal Conditions: Elspa-DM Tablet can also be used to alleviate pain and discomfort caused by gastrointestinal conditions, including irritable bowel syndrome.

Directions for Use

• Take Elspa-DM Tablet with food to avoid stomach upset or as advised by a doctor. • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety. • Swallow the medicine as a whole with glass of water. • Do not crush, break, or chew it.

Medicinal Benefits

Elspa-DM Tablet is a combination of two drugs: Drotaverine and Mefenamic acid. Elspa-DM Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Elspa-DM Tablet helps in relieving pain.

How Elspa-DM Tablet Works

Elspa-DM Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Elspa-DM Tablet helps in relieving pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Elspa-DM Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Elspa-DM Tablet

Do not take more than the prescribed dose of Elspa-DM Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Elspa-DM Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Elspa-DM Tablet unless prescribed by the doctor, as Elspa-DM Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Elspa-DM Tablet may cause dizziness, so drive only if you are alert. Elspa-DM Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Elspa-DM Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Elspa-DM Tablet unless prescribed.

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
Mefenamic acidMeloxicam
Critical

Drug-Drug Interactions

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Mefenamic acidKetorolac
Critical
How does the drug interact with Elspa-DM Tablet:
Coadministration of Elspa-DM Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Elspa-DM Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidMeloxicam
Critical
How does the drug interact with Elspa-DM Tablet:
Co-administration of Elspa-DM Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Elspa-DM Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidHuman immunoglobulin
Severe
How does the drug interact with Elspa-DM Tablet:
Taking Human immunoglobulin with Elspa-DM Tablet, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Elspa-DM Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Elspa-DM Tablet:
Coadministration of Elspa-DM Tablet with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Elspa-DM Tablet with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCidofovir
Severe
How does the drug interact with Elspa-DM Tablet:
Coadministration of cidofovir with Elspa-DM Tablet can increase the risk of kidney problems.

How to manage the interaction:
Although taking Elspa-DM Tablet and cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidFondaparinux
Severe
How does the drug interact with Elspa-DM Tablet:
Taking Elspa-DM Tablet with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Fondaparinux with Elspa-DM Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding or bruising, feeling dizzy or lightheaded, dark or bloody stools, headache, weakness contact your doctor right away. Do not stop using any medications without first talking to your doctor.
Mefenamic acidMethotrexate
Severe
How does the drug interact with Elspa-DM Tablet:
Coadministration of Elspa-DM Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Elspa-DM Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Mefenamic acidWarfarin
Severe
How does the drug interact with Elspa-DM Tablet:
Coadministration of Elspa-DM Tablet with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Elspa-DM Tablet with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidDalteparin
Severe
How does the drug interact with Elspa-DM Tablet:
Combining Elspa-DM Tablet with Dalteparin can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Dalteparin and Elspa-DM Tablet together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any signs like bleeding, bruising, swelling, vomiting, headache, dizziness, weakness, or blood in your urine or stool, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Mefenamic acidBaricitinib
Severe
How does the drug interact with Elspa-DM Tablet:
Using Elspa-DM Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Elspa-DM Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Elspa-DM Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Elspa-DM Tablet as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Elspa-DM Tablet if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Elspa-DM Tablet may cause drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

Elspa-DM Tablet should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Elspa-DM Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery.

Elspa-DM Tablet contains Drotaverine and Mefenamic acid. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of Elspa-DM Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Dry mouth could be a side-effect of Elspa-DM Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not take Elspa-DM Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Elspa-DM Tablet only for as long as your doctor has prescribed it.

Elspa-DM Tablet is generally prescribed for short durations and can be discontinued after pain relief. However, you are advised to continue taking Elspa-DM Tablet for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Elspa-DM Tablet.

Elspa-DM Tablet is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Elspa-DM Tablet only as prescribed, and do not overdose.

Elspa-DM Tablet may cause dizziness, so drive with caution and only if you are alert. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Stop taking Elspa-DM Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

No, do not take Elspa-DM Tablet on an empty stomach. Take it with food to prevent stomach upset.

Elspa-DM Tablet usually starts working within an hour. However, this might vary individually based on the physical condition.

The doctor will determine the daily dose of Elspa-DM Tablet based on your condition. Please consult the doctor if you have any concerns.

Elspa-DM Tablet is a combination medicine containing Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). It is used to relieve abdominal pain associated with various conditions.

Yes, Elspa-DM Tablet is safe if taken in the dose and duration prescribed by the doctor.

Yes, Elspa-DM Tablet may cause nausea and vomiting as a side effect. If you have nausea and vomiting, get fresh air, take sips of water regularly, and eat smaller, frequent meals. Consult the doctor if the condition persists or worsens.

No, do not take a higher than the recommended dose of Elspa-DM Tablet as it may cause overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Store Elspa-DM Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.

Yes, Elspa-DM Tablet can be taken with food. Taking Elspa-DM Tablet with food helps prevent stomach upset.

Common side effects of Elspa-DM Tablet are gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Elspa-DM Tablet can be used during pregnancy or breastfeeding if advised by the doctor. The doctor will prescribe Elspa-DM Tablet only if the benefits outweigh the risks.

Do not take Elspa-DM Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Take Elspa-DM Tablet only for as long as your doctor has prescribed it.

If you miss a dose of Elspa-DM Tablet, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Country of origin

India

Manufacturer/Marketer address

344/1/2/1, fairdeal ware house, b/h. ekta hotel, nr. ujala circle, bavla road, sarkhej, ahmedabad - 382210, gujarat - india
Other Info - EL64572

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 5, 2025 | 1:06 PM IST

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Reference

  1. https://www.bionova.co.in/drotafix-tablet.html
  2. https://www.ravimiregister.ee/Data/PIL_ENG/PIL_11232_ENG.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/015034s040lbl.pdf
  4. https://www.drugs.com/cdi/mefenamic-acid.html
  5. https://www.hpra.ie/img/uploaded/swedocuments/eec4b0f8-a82a-4ba9-8e04-d411ee4d7b95.pdf
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