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  3. Enalapril 5mg Tablet

Enalapril 5mg Tablet, Pack of 1 Tablet
Enalapril 5mg Tablet, Pack of 1 Tablet
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Enalapril 5mg Tablet is used to treat high blood pressure and heart failure. It contains Enalapril, which widens and relaxes the blood vessels and, therefore, help lower high blood pressure. In some cases, you may experience side effects such as headaches, ankle swelling, slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ENALAPRIL-5MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Enalapril 5mg Tablet

Enalapril 5mg Tablet is used to treat high blood pressure and heart failure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Enalapril 5mg Tablet lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Enalapril 5mg Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure. 

In some cases, you may experience headaches, ankle swelling, slow heart rate, and nausea. Enalapril 5mg Tablet may lower your blood pressure, especially if taken with alcohol. So, avoid driving and operating heavy machinery. Most of these side effects of Enalapril 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Even if your blood pressure becomes normal, you should not stop using Enalapril 5mg Tablet; doing so may worsen your condition. Let your doctor know if you have had or currently have any liver, kidney, or heart problems. During pregnancy and lactation, Enalapril 5mg Tablet should be only taken after consulting your doctor. You should regularly monitor your blood pressure and heart rate.

Uses of Enalapril 5mg Tablet

Treatment of High blood pressure, Prevention of Congestive heart failure.

Directions for Use

Swallow Enalapril 5mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Enalapril 5mg Tablet is primarily used to treat hypertension or high blood pressure. In combination therapy, it is also prescribed with other drugs, like thiazide diuretics (water pills). Besides, Enalapril 5mg Tablet prevents congestive heart failure in combination with diuretics (water pills) and cardiac glycosides like digitalis. In these patients, Enalapril 5mg Tablet improves heart complications, increases survival, and reduces hospitalization frequency.

How Enalapril 5mg Tablet Works

Enalapril 5mg Tablet lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Enalapril 5mg Tablet allows these constricted blood vessels to relax and, therefore, help lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Enalapril 5mg Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of Enalapril 5mg Tablet

Do not take more than the prescribed dose of Enalapril 5mg Tablet as it may cause overdose. The symptoms of overdose include sleepiness, dizziness and pounding heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Enalapril 5mg Tablet should not be given to the people allergic to Enalapril 5mg Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, tell your doctor if you have low blood pressure (hypotension),  heart disease, liver disease, kidney disease, or are currently on dialysis. Enalapril 5mg Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The level of raised bilirubin has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye etc.) should take the Enalapril 5mg Tablet with caution. Do not take Enalapril 5mg Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor that, you are using Enalapril 5mg Tablet before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery.

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
EnalaprilAmiloride
Severe

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Using aliskiren together with Enalapril 5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enalapril 5mg Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
EnalaprilAmiloride
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Using Enalapril 5mg Tablet together with amiloride may increase the levels of potassium in your blood, especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking amiloride and Enalapril 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not discontinue any medications without a doctor's advice.
EnalaprilPotassium acetate
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Combining Enalapril 5mg Tablet and Potassium acetate may result in significantly higher blood potassium levels. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscle paralysis, abnormal heart rhythm

How to manage the interaction:
Although taking Enalapril 5mg Tablet and Potassium acetate together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience nausea, vomiting, weakness, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without a doctor's advice.
EnalaprilPotassium citrate
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Taking Enalapril 5mg Tablet with Potassium citrate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enalapril 5mg Tablet together with Potassium citrate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilMipomersen
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
When mipomersen is used with other drugs that can potentially damage the liver, like Enalapril 5mg Tablet, the risk of liver issues increases.

How to manage the interaction:
Although taking Enalapril 5mg Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - joint pain, swelling, skin rash, itching, fatigue, abdominal pain, or dark urine - immediately contact your doctor. Do not stop using any medications without a doctor's advice.
EnalaprilTizanidine
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Enalapril 5mg Tablet, when taken together with Tizanidine, may lead to hypotension (low blood pressure) due to the additive effect.

How to manage the interaction:
Although taking Enalapril 5mg Tablet together with Tizanidine may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hypotension, such as headache, dizziness, drowsiness, fainting, or irregular heartbeat. It is advised not to drive or operate any machinery that requires alertness and to be cautious when getting up from a sitting or lying position. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium gluconate
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Taking Enalapril 5mg Tablet with Potassium gluconate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enalapril 5mg Tablet together with Potassium gluconate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilIrbesartan
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Using Enalapril 5mg Tablet together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Enalapril 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.
EnalaprilTelmisartan
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Coadministration of Enalapril 5mg Tablet with Telmisartan may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Enalapril 5mg Tablet together with Telmisartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, papayas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilTeriflunomide
Severe
How does the drug interact with Enalapril 5mg Tablet 5mg Tablet:
Teriflunomide can cause liver damage, and taking it with medications like Enalapril 5mg Tablet, which have a similar effect, increases the risk.

How to manage the interaction:
Although taking Enalapril 5mg Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, contact your doctor if you experience fever, chills, joint discomfort, swelling, skin irritation, itching, tiredness, stomach ache, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming a high-potassium diet while taking Enalapril 5mg Tablet can cause hyperkalemia (elevated blood potassium levels). Hyperkalemia may lead to dizziness, lightheadedness, fainting, or a rapid heartbeat. Avoid the consumption of potassium-rich foods.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two serving for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.
  • Including heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Enalapril 5mg Tablet Substitute

Substitutes safety advice

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Product Substitutes

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Alcohol

Unsafe

Enalapril 5mg Tablet may enhance the hypotensive (low blood pressure) effect of this drug. For better advise, you should consult your doctor whether you can take Enalapril 5mg Tablet with alcohol.

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Pregnancy

Unsafe

The use of Enalapril 5mg Tablet or any ACE inhibitors is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Enalapril 5mg Tablet.

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Breast Feeding

Caution

Use of Enalapril 5mg Tablet is not recommended during breastfeeding stage.

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Driving

Unsafe

Drive with caution, Enalapril 5mg Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Rare elevation in the liver enzymes (like bilirubin) have been observed while taking Enalapril 5mg Tablet, so it has to be taken with caution. Especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Enalapril 5mg Tablet to be taken with caution, especially in case of severe kidney disease. Dose may have to be adjusted by your doctor. Enalapril 5mg Tablet should be given with precaution in hemodialysis condtion.

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Children

Caution

Enalapril 5mg Tablet is not recommended for children. The safety and effectivenss of Enalapril 5mg Tablet has not been established in children due to limited testing of this drug on children by competent authorities across the world. If necessary, your doctor will decide whether to give Enalapril 5mg Tablet or not.

Have a query?

FAQs

Enalapril 5mg Tablet is used to treat high blood pressure and heart failure.

Enalapril 5mg Tablet is an angiotensin-converting enzyme (ACE) inhibitor. It works by inhibiting a chemical in the body that causes blood vessels to constrict. As a result, enalapril relaxes the blood vessels. This decreases blood pressure while increasing the delivery of blood and oxygen to the heart.

No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal as blood pressure can shot up any time. If you have any discomfort, please consult your doctor immediately.

Before surgery, you should inform your doctor that you are taking Enalapril 5mg Tablet as it can reduce your blood pressure when used along with anaesthesia which is given before a major operation.

If you forget to take Enalapril 5mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Enalapril 5mg Tablet may cause side effects such as nausea, weakness, cough, dizziness and blurred vision. If these side effects persist or worsen, please consult your doctor.

No, Enalapril 5mg Tablet does not cause excessive urination. Normal kidney function may not be affected by Enalapril 5mg Tablet. However, when Enalapril 5mg Tablet is given with a diuretic (water pill, a medicine that increases the urine output), kidney damage may occur. In this case, either the diuretic should be stopped or its dose should be lowered. If you have severe heart failure or your kidneys are already affected then there is a risk of kidney failure. However, kidney damage can be reversed by timely and appropriate treatment.

Rarely, Enalapril 5mg Tablet may cause yellowing of skin and eyes, an increase in liver enzymes and loss of appetite. Additionally, it might cause significant liver damage and even death. Therefore, if you experience any such symptoms, contact your doctor immediately.

You should be cautious when taking Enalapril 5mg Tablet with hydrochlorothiazide, as it can further lower your blood pressure. You may also develop kidney failure symptoms, such as a reduced amount of urine, swelling of your legs, ankles, and feet from water retention. While others may experience unexplained shortness of breath, persistent nausea, excessive drowsiness or fatigue, pain, confusion, or pressure in your chest and seizures (fits). These symptoms typically occur if there is considerable water or salt loss prior to starting Enalapril 5mg Tablet. Therefore, if you experience any of these symptoms, contact your doctor who will either advise you to stop taking hydrochlorothiazide or lower the dose. The doctor may also recommend you Enalapril 5mg Tablet in very low doses when used in combination with hydrochlorothiazide.

You are recommended to avoid taking ibuprofen with Enalapril 5mg Tablet as there is a risk of kidney damage and may reduce the effectiveness of Enalapril 5mg Tablet. However, please consult your doctor before taking Enalapril 5mg Tablet with other medicines.

Enalapril 5mg Tablet starts working within few hours. However, it may take few weeks to see its full effects. After taking Enalapril 5mg Tablet for high blood pressure, you may not notice any difference until you get your blood pressure checked. It may take few weeks to months before you start feeling better, if you are taking Enalapril 5mg Tablet for heart failure.

You should take Enalapril 5mg Tablet for as long as it is advised by your doctor. You might need to take it lifelong, until and unless any serious side effect starts bothering and stops you from taking it. However, do not stop taking it without first consulting your doctor.

Yes, Enalapril 5mg Tablet can be taken for long term as it is generally well tolerated by most people. However, long-term usage of it can sometimes impair your kidneys functioning. Your doctor will recommend regular blood tests to check whether your kidneys are functioning properly or not.

Country of origin

India
Other Info - EN57727

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:50 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6106.pdf
  2. https://www.medicines.org.uk/emc/files/pil.2666.pdf
  3. https://www.medicines.org.uk/emc/product/2666/smpc#gref
  4. https://www.nhs.uk/medicines/enalapril/
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