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compositionComposition:ENALAPRIL-5MG
prescription
Prescription Medicine
info
Cardiril 5mg Tablet

Cardiril 5mg Tablet is used to treat hypertension and heart failure. It relaxes and widens blood vessels, helping the heart pump blood more easily. This helps reduce symptoms like swelling, shortness of breath, and tiredness, and lowers the risk of hospitalisation and complications such as heart attack, stroke, and kidney damage.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ENALAPRIL-5MG

Manufacturer/Marketer :

Shine Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Cardiril 5mg Tablet

Cardiril 5mg Tablet is a prescription medicine used to lower high blood pressure and help manage heart failure. By keeping your blood pressure under control, this medicine reduces the risk of serious cardiovascular events like strokes or heart attacks. It is also used to protect the heart in patients who have a weakened heart muscle.

For the best results, you should take this medicine consistently every single day at the same time. You can take it with or without food, as eating does not change how the medicine is absorbed. Adopting healthy habits, such as eating a low-salt diet and getting regular physical activity, will significantly improve how well this medicine works for you.

While taking this medicine, you might experience mild side effects like a dry cough or mild lightheadedness when you stand up. However, you must contact your healthcare provider immediately if you experience serious symptoms, such as severe dizziness, difficulty breathing, or sudden swelling of your lips and face.

Talk to your doctor before starting this medicine if you have kidney disease, diabetes, or a history of severe allergic swelling. Do not take this if you are pregnant, planning to become pregnant, or if you have ever had a severe allergic reaction to similar blood pressure medicines.

Cardiril 5mg Tablet may also be prescribed in certain children with specific heart or kidney conditions. Treatment in children should always be supervised by a specialist, with dosing adjusted according to the child's age, weight, and medical condition.

This medicine can interact with other drugs like potassium supplements or water pills, which can cause your potassium levels to rise too high. It is also important to limit alcohol intake while taking this medicine to avoid unsafe drops in blood pressure. If you are breastfeeding, elderly, or have complex medical conditions, consult your doctor or pharmacist before starting treatment.
 

Uses of Cardiril 5mg Tablet

Doctors prescribe Cardiril 5mg Tablet to treat and manage several cardiovascular conditions:

  • High blood pressure (hypertension): It relaxes and widens your blood vessels, which lowers your blood pressure and makes it easier for blood to flow.
  • Heart failure: It reduces the workload on your heart, helping it pump blood more efficiently and easing symptoms like shortness of breath and fluid retention.
  • Left ventricular dysfunction: It helps prevent heart failure from worsening in patients who have a weakened main heart chamber, especially after a heart attack.

Key Benefits

Cardiril 5mg Tablet provides important long-term protective benefits and helps improve your physical comfort:

  • Protects vital organs: By maintaining stable blood pressure, Cardiril 5mg Tablet helps prevent long-term damage to critical organs like your kidneys, brain, and eyes.
  • Improves physical comfort: For people with heart weakness, it decreases physical strain, helping you breathe more easily and participate in daily activities without feeling prematurely exhausted.
  • Reduces emergency risks: Regular daily use helps keep your condition stable, which significantly lowers your risk of needing emergency hospital stays due to heart complications.
Side effects of Cardiril 5mg Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Directions for Use

To get the safest and most effective results from your medicine, follow these instructions:

  • Swallow the tablet whole with a full glass of water.
  • You can take this medicine either with or without food.
  • Try to take it at the same time each day to maintain consistent levels in your body.
  • Do not crush, chew, or split the tablet unless your healthcare provider specifically instructs you to do so.
  • Always follow your doctor's exact instructions regarding your dose and schedule.

How Cardiril 5mg Tablet Works

Enalapril, the active ingredient in Cardiril 5mg Tablet, belongs to a group of medicines called ACE inhibitors. It is converted in the body to its active form, enalaprilat, which blocks a specific enzyme responsible for producing a chemical that narrows blood vessels. When this chemical is reduced, blood vessels relax and widen, helping lower blood pressure and reducing the workload on the heart. This action helps gradually lower blood pressure over time, allowing the heart to pump blood more efficiently. Because Cardiril 5mg Tablet requires activation in the body, it may take some time for its full effects to develop, and patients with severe liver impairment may require closer medical supervision.
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Alcohol

Unsafe

Cardiril 5mg Tablet may enhance the hypotensive (low blood pressure) effect of this drug. For better advise, you should consult your doctor whether you can take Cardiril 5mg Tablet with alcohol.

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Pregnancy

Unsafe

Cardiril 5mg Tablet is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing foetus. Therefore, you should consult your physician before using Cardiril 5mg Tablet.

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Breast Feeding

Caution

Using Cardiril 5mg Tablet is not recommended during breastfeeding.

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Driving

Unsafe

Drive with caution, as Cardiril 5mg Tablet may cause blurry vision and dizziness.

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Liver

Caution

Rare elevations in liver enzymes (such as bilirubin) have been observed while taking Cardiril 5mg Tablet, so it should be taken with caution, especially if you have a history of liver disease or conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Cardiril 5mg Tablet should be used with caution, especially in cases of severe kidney disease. The dose may have to be adjusted by your doctor. Cardiril 5mg Tablet should be used with caution in patients on haemodialysis.

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Children

Caution

Cardiril 5mg Tablet is not recommended for children, as its safety and efficacy have not been established in this population. Please consult your doctor to decide whether to give Cardiril 5mg Tablet to your child.

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Heart

Safe if prescribed

Cardiril 5mg Tablet is generally considered safe for patients with heart disease. However, it is advisable to consult your doctor before using Cardiril 5mg Tablet.

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Geriatrics

Consult your doctor

Cardiril 5mg Tablet should be used in elderly patients only when prescribed by a doctor. Consult your healthcare provider to determine the appropriate dose and duration of treatment.

What if I have taken an overdose of Cardiril 5mg Tablet

Do not take more than the prescribed dose of Cardiril 5mg Tablet, as it may cause serious side effects. If you suspect you have taken an overdose or notice any unusual symptoms, please consult a doctor immediately.

Diet & Lifestyle Advise

Making specific daily changes can help your medicine work more effectively and keep you safe:

  • Avoid potassium-based salt substitutes: This medicine can cause your body to retain potassium. Using salt substitutes that contain potassium can lead to dangerously high levels in your blood.
  • Adopt a low-sodium diet: Reducing your daily salt intake helps your medicine work more effectively to lower your blood pressure and reduce fluid build-up.
  • Stay safely hydrated: Unless your doctor has advised you to limit fluids, make sure to drink enough water. Dehydration can increase the risk of dizziness and kidney strain while taking this medicine.
  • Limit your alcohol intake: Drinking alcohol can cause your blood pressure to drop too low when combined with this medicine, leading to severe dizziness or fainting.
     

Have a query?

How Soon It Starts Working

  • The time required for Cardiril 5mg Tablet to start to work: Cardiril 5mg Tablet ideally shows its action within 2 to 4 hours after administration.
  • The time for which the effects of Cardiril 5mg Tablet last: The effect of Cardiril 5mg Tablet lasts for 12 to 24 hours.

What if you forget to take Cardiril 5mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Keep these vital safety precautions in mind while using this medication:

  • Stand up slowly: To prevent dizziness or falls, take your time when moving from a sitting or lying position to a standing one.
  • Check over-the-counter medicines: Talk to your pharmacist before taking cold, allergy, or cough medicines, as many contain decongestants that can raise your blood pressure.
  • Keep your medical appointments: You will need regular blood tests to monitor your kidney health and check the potassium levels in your blood while taking this medicine.
  • Stop immediately if you suspect pregnancy: This medicine can cause serious harm to an unborn baby. Contact your doctor immediately if you think you are pregnant.

Be cautious in hot weather: Heavy sweating or dehydration from heat can cause your blood pressure to drop too low, making you feel faint.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Potassium supplements or potassium-sparing water pills: May lead to dangerously high levels of potassium in your blood, which can affect your heart rhythm.
  • Other blood pressure medications: Can excessively lower your blood pressure or increase the risk of kidney strain.
    NSAIDs (like ibuprofen or naproxen): Can reduce the blood-pressure-lowering effect of this medicine and increase the risk of severe kidney damage.
  • Lithium: Can cause toxic levels of lithium to build up in your body, leading to serious side effects.
  • Sacubitril/Valsartan (ARNI): Do not take Cardiril 5mg Tablet together with sacubitril/valsartan. Combining these medicines significantly increases the risk of angioedema, a potentially life-threatening swelling of the face, tongue, or throat. 


Drug-Food Interactions

Potassium-rich salt substitutes: Can cause a dangerous increase in blood potassium levels when taken alongside this medicine.


Drug-Disease Interactions

  • Kidney disease: May require closer monitoring of kidney function and blood tests to avoid worsening renal health.
  • Diabetes: Combining this medicine with certain other diabetes drugs (like aliskiren) is generally not recommended in people with diabetes or kidney impairment because it may increase the risk of low blood pressure, elevated potassium levels, and worsening kidney function.
  • History of angioedema: Do not take this medicine if you have a history of swelling of the face, tongue, or throat, as it can trigger a life-threatening airway blockage.
EnalaprilAliskiren
Critical
EnalaprilPotassium citrate
Severe

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Cardiril 5mg Tablet:
Using aliskiren together with Cardiril 5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Cardiril 5mg Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Cardiril 5mg Tablet:
Taking Cardiril 5mg Tablet with Potassium citrate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Cardiril 5mg Tablet together with Potassium citrate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilLeflunomide
Severe
How does the drug interact with Cardiril 5mg Tablet:
Cardiril 5mg Tablet has the potential to cause liver damage; this effect can be increased by the coadministration of medications that affect the liver, such as Leflunomide. This effect can be seen even long after discontinuing leflunomide as it stays in your blood longer.

How to manage the interaction:
Although taking Cardiril 5mg Tablet together with Leflunomide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of liver damage like fever, chills, unusual bleeding, dark-coloured urine, light colour stools, yellowish discolouration of skin and eyes, and abdominal pain. It is advised not to consume alcohol while using these medications as it may increase the damage o the liver. Do not discontinue any medications without consulting your doctor.
EnalaprilLithium
Severe
How does the drug interact with Cardiril 5mg Tablet:
Taking Lithium with Cardiril 5mg Tablet may significantly increase the blood levels of lithium.

How to manage the interaction:
Co-administration of Cardiril 5mg Tablet with Lithium can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience drowsiness, dizziness, loose stools, vomiting, muscle weakness, shaking of hands and legs, excessive thirst, and increased urination. Do not discontinue any medications without consulting a doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Cardiril 5mg Tablet:
Taking potassium citrate with Cardiril 5mg Tablet may increase potassium levels in the blood, leading to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Cardiril 5mg Tablet with Potassium citrate can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without a doctor's advice.
EnalaprilTizanidine
Severe
How does the drug interact with Cardiril 5mg Tablet:
Cardiril 5mg Tablet, when taken together with Tizanidine, may lead to hypotension (low blood pressure) due to the additive effect.

How to manage the interaction:
Although taking Cardiril 5mg Tablet together with Tizanidine may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hypotension, such as headache, dizziness, drowsiness, fainting, or irregular heartbeat. It is advised not to drive or operate any machinery that requires alertness and to be cautious when getting up from a sitting or lying position. Do not discontinue any medication without consulting your doctor.
EnalaprilPotassium gluconate
Severe
How does the drug interact with Cardiril 5mg Tablet:
Taking Cardiril 5mg Tablet with Potassium gluconate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Cardiril 5mg Tablet together with Potassium gluconate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilTriamterene
Severe
How does the drug interact with Cardiril 5mg Tablet:
Taking Cardiril 5mg Tablet together with triamterene may increase the levels of potassium in your blood (hyperkalemia), especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking Cardiril 5mg Tablet with Triamterene may result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience weakness, confusion, numbness or tingling. Do not discontinue any medication without consulting your doctor.
EnalaprilAmiloride
Severe
How does the drug interact with Cardiril 5mg Tablet:
Due to the additive effect, the coadministration of Cardiril 5mg Tablet and Amiloride (potassium-sparing diuretic) may increase blood potassium levels. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Cardiril 5mg Tablet together with Allopurinol may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any signs and symptoms of hyperkalemia like, weakness, confusion, numbness or tingling, and uneven heartbeats, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
EnalaprilAmiloride
Severe
How does the drug interact with Cardiril 5mg Tablet:
Using Cardiril 5mg Tablet together with amiloride may increase the levels of potassium in your blood, especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking amiloride and Cardiril 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming a high-potassium diet while taking Cardiril 5mg Tablet can cause hyperkalemia (elevated blood potassium levels). Hyperkalemia may lead to dizziness, lightheadedness, fainting, or a rapid heartbeat. Avoid the consumption of potassium-rich foods.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Cardiril 5mg Tablet is used to treat hypertension (high blood pressure). It is also used to treat heart failure and help prevent its symptoms.
Cardiril 5mg Tablet contains Enalapril, which works by blocking a naturally occurring substance called angiotensin II, which tightens the blood vessels. Cardiril 5mg Tablet relaxes and widens the blood vessels, thereby helping to lower high blood pressure and reduce the heart’s workload.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Before surgery, you should inform your doctor that you are taking Cardiril 5mg Tablet as it can reduce your blood pressure when used along with anaesthesia, which is given before a major operation.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one entirely and continue with your normal routine. Never take a double dose to make up for a missed one. Talk to your doctor.
Cardiril 5mg Tablet may cause side effects such as nausea, weakness, cough, dizziness and blurred vision. If these side effects persist or worsen, please consult your doctor.
No, Cardiril 5mg Tablet does not cause excessive urination. Normal kidney function may not be affected by Cardiril 5mg Tablet. However, when Cardiril 5mg Tablet is given with a diuretic (water pill, a medicine that increases the urine output), kidney damage may occur. In this case, either the diuretic should be discontinued or its dose reduced. If you have severe heart failure or your kidneys are already affected, then there is a risk of kidney failure. However, kidney damage can be reversed by timely and appropriate treatment.
Rarely, Cardiril 5mg Tablet may cause yellowing of the skin and eyes, increased liver enzymes, and loss of appetite. Additionally, it might cause significant liver damage and even death. Therefore, if you experience any such symptoms, contact your doctor immediately.
You should be cautious when taking Cardiril 5mg Tablet with hydrochlorothiazide, as it can further lower your blood pressure. You may also develop kidney failure symptoms, such as reduced urine output and swelling of your legs, ankles, and feet due to water retention. While others may experience unexplained shortness of breath, persistent nausea, excessive drowsiness or fatigue, pain, confusion, or pressure in the chest and seizures (fits). These symptoms typically occur if there is considerable water or salt loss prior to starting Cardiril 5mg Tablet. Therefore, if you experience any of these symptoms, contact your doctor, who will either advise you to stop taking hydrochlorothiazide or lower the dose. The doctor may also recommend you Cardiril 5mg Tablet in very low doses when used in combination with hydrochlorothiazide.
Cardiril 5mg Tablet starts working within a few hours. However, it may take a few weeks to see its full effects. After taking Cardiril 5mg Tablet for high blood pressure, you may not notice any difference until you get your blood pressure checked. It may take a few weeks to months before you start feeling better, if you are taking Cardiril 5mg Tablet for heart failure.
You should take Cardiril 5mg Tablet for as long as your doctor advises. High blood pressure and heart failure are often long-term conditions, so treatment may be needed for many years or even lifelong. Do not stop taking Cardiril 5mg Tablet without consulting your doctor, even if your blood pressure is under control or you feel well, as stopping treatment may cause your condition to worsen.
Yes, Cardiril 5mg Tablet can be used long-term, as it is generally well tolerated by most people. However, long-term use can impair kidney function. Your doctor will recommend regular blood tests to check whether your kidneys are functioning properly.
No, Cardiril 5mg Tablet is generally not recommended during pregnancy because it can cause serious harm to an unborn baby, particularly during the second and third trimesters. If you are pregnant, think you may be pregnant, or are planning a pregnancy, contact your doctor immediately. Do not stop or change your treatment without medical guidance, as your doctor can advise you on safer alternative treatment options.
This medicine can cause a buildup of a natural chemical called bradykinin in your airway, which can trigger a dry, tickly cough in some people. This cough is harmless but does not respond to standard cough medicines. If the cough becomes severe or keeps you awake, talk to your doctor.
Yes, you should avoid salt substitutes that contain potassium, as well as high-dose potassium supplements, because this medicine can naturally raise potassium levels in your blood. Consuming extra potassium can lead to unsafe heart rhythms. Talk to your doctor.
You should avoid taking pain relievers like ibuprofen or naproxen regularly while on this medicine. These drugs can prevent Cardiril 5mg Tablet from lowering your blood pressure effectively and can also increase the risk of kidney damage. Consult your doctor before using ibuprofen or other painkillers with Cardiril 5mg Tablet.
Yes, this medicine reduces the amount of potassium your kidneys filter out, which can cause potassium to build up in your blood. Your doctor will perform regular blood tests to monitor your potassium levels and ensure they stay within a safe range. Talk to your doctor.
Yes, Cardiril 5mg Tablet may be prescribed for certain children with specific heart or kidney conditions. Treatment should only be given under specialist supervision, and the dose is carefully adjusted based on the child's age, weight, and medical condition.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.6106 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.2666 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. National Health Service (NHS). Enalapril - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Enalapril Enalapril. 1985. [Accessed on 18 Mar. 2019] Check here
  6. Enalapril maleate [Drug Label]. 2014. [Accessed on 25 Jul. 2024] Check here
  7. Enalapril maleate [Drug Label]. 2025. [Accessed on 27 Jan. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

308-310 Dwarkesh Complex, Sun Pharma Road, Po:Atladra, Vadodara-390 012., Gujarat, India.
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