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compositionComposition:NIMESULIDE-100MG+PARACETAMOL-325MG
prescription
Prescription Medicine
info
ENDOLIDE DT TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

NIMESULIDE-100MG+PARACETAMOL-325MG

Manufacturer/Marketer :

Endocard India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ENDOLIDE DT TABLET

ENDOLIDE DT TABLET is a prescription medication used to treat acute pain, painful joint conditions like osteoarthritis, and fever. It combines two active pain-relieving components to target pain and swelling at their source. This medicine helps reduce discomfort caused by dental pain, menstrual cramps, or joint inflammation.

It is typically taken only for short durations as prescribed by your healthcare provider to manage sudden flare-ups of pain. You should always take ENDOLIDE DT TABLET with or after a meal to help protect your stomach from irritation. Adopting a balanced diet and avoiding strenuous physical activity during recovery can also support your body's natural healing process.

While taking ENDOLIDE DT TABLET, some people may experience mild side effects like nausea, stomach discomfort, or dizziness. However, if you notice signs of liver damage, such as yellowing of your skin or eyes, dark urine, or severe stomach pain, you must stop taking the medicine and consult your doctor immediately.

Do not take this if you have active stomach ulcers, severe liver or kidney disease, or a history of heart problems. It is vital to talk to your doctor before starting ENDOLIDE DT TABLET if you have asthma, high blood pressure, or a history of bleeding disorders.

Taking this medicine with other pain relievers can strain your kidneys, and combining it with alcohol significantly increases your risk of liver damage. If you are pregnant, breastfeeding, or elderly, you must consult your healthcare provider before using this medicine to ensure it is safe for you.

Uses of ENDOLIDE DT TABLET

  • Always take ENDOLIDE DT TABLET exactly as prescribed by your doctor. Do not alter your dose or stop taking it without their advice.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is released in your body.
  • Take this medicine with or immediately after a meal to help protect your stomach lining from irritation.
  • Do not take this medicine for longer than recommended by your healthcare provider to protect your liver and kidneys.

Key Benefits

ENDOLIDE DT TABLET provides effective relief from pain and fever, helping you regain comfort and return to your daily activities with greater ease. By combining multiple therapeutic actions in a single medicine, it offers several key benefits:

  • Fast-Acting Pain Relief: By combining two distinct pain-relieving mechanisms, ENDOLIDE DT TABLET provides rapid relief from moderate to severe pain, helping you return to your daily activities quickly.
  • Improved Mobility: For those suffering from joint conditions, it lowers inflammation, which directly improves flexibility and allows for smoother, pain-free movement.
  • Dual-Action Care: It simultaneously targets both pain and fever, eliminating the need to take multiple single-ingredient medications for systemic symptoms.
Side effects of Endolide Dt Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.

Directions for Use

ENDOLIDE DT TABLET works through a combination of two active components that target pain and fever from different angles. This dual-action approach ensures faster and more comprehensive relief than single-ingredient alternatives.

The first active component works locally at the site of injury or inflammation. It blocks specific chemical messengers in the body, known as COX-2 enzymes, which are responsible for causing pain, redness, and swelling. By halting these messengers, it reduces localised pain and joint inflammation.

The second active component acts primarily in the central nervous system. It interrupts pain signals travelling to the brain and influences the heat-regulating centre of the brain to lower body temperature during a fever. Together, these two mechanisms provide a synergistic effect that relieves discomfort quickly and safely when used as directed.
 

How ENDOLIDE DT TABLET Works

ENDOLIDE DT TABLET works through a combination of two active components that target pain and fever from different angles. This dual-action approach ensures faster and more comprehensive relief than single-ingredient alternatives. The first active component works locally at the site of injury or inflammation. It blocks specific chemical messengers in the body, known as COX-2 enzymes, which are responsible for causing pain, redness, and swelling. By halting these messengers, it reduces localised pain and joint inflammation. The second active component acts primarily in the central nervous system. It interrupts pain signals travelling to the brain and influences the heat-regulating centre of the brain to lower body temperature during a fever. Together, these two mechanisms provide a synergistic effect that relieves discomfort quickly and safely when used as directed.
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Alcohol

Unsafe

Taking ENDOLIDE DT TABLET with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with ENDOLIDE DT TABLET.

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Pregnancy

Unsafe

Use of ENDOLIDE DT TABLET during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Use of ENDOLIDE DT TABLET during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.

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Driving

Unsafe

After taking ENDOLIDE DT TABLET, you may notice dizziness, sleepiness, drowsiness. So, you should stop taking ENDOLIDE DT TABLET and contact your doctor.

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Liver

Caution

ENDOLIDE DT TABLET to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

ENDOLIDE DT TABLET to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

ENDOLIDE DT TABLET is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

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Heart

Unsafe

ENDOLIDE DT TABLET should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

ENDOLIDE DT TABLET should be given with caution in geriatrics due to increased risk of side effects. If you have any concerns about using ENDOLIDE DT TABLET, please consult a doctor.

What if I have taken an overdose of ENDOLIDE DT TABLET

Do not take more than the prescribed dose of ENDOLIDE DT TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat stomach-friendly meals: Since this medicine can irritate the stomach lining, pair your doses with simple, non-spicy foods like rice, toast, or oatmeal.
  • Stay well-hydrated: Drink plenty of water throughout the day. This helps your kidneys process the medicine safely and keeps you hydrated, especially if you have a fever.
  • Avoid alcohol completely: Alcohol increases the strain on your liver and elevates the risk of stomach ulcers when combined with ENDOLIDE DT TABLET.
  • Incorporate gentle movement: If you are taking this for joint pain, light activities like walking or stretching can help maintain joint mobility without overexerting yourself.
  • Get adequate rest: Rest is essential for tissue repair and recovery, allowing the medicine to work effectively.

Have a query?

How Soon It Starts Working

  • The time required for ENDOLIDE DT TABLET to start to work: The time required for ENDOLIDE DT TABLET to start to work is 1 hour after administration.
  • The time for which the effects of ENDOLIDE DT TABLET last: The effect of ENDOLIDE DT TABLET lasts for 6 hours.

What if you forget to take ENDOLIDE DT TABLET

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store ENDOLIDE DT TABLET tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the tablets in their original blister packaging to protect them from moisture and direct light.

Drug Warnings

  • Limit treatment duration: Do not use ENDOLIDE DT TABLET for more than 15 consecutive days, or as advised by your doctor, to prevent potential liver injury.
  • Check other pain medications: Avoid taking other pain relievers, cold medicines, or fever reducers while taking ENDOLIDE DT TABLET to prevent accidental double-dosing of similar active ingredients.
  • Monitor for skin changes: Stop the medication immediately if you develop any unexplained skin rash, blistering, or mucosal peeling, as these can be early signs of rare but severe skin reactions.
  • Avoid if you have a history of bleeding: If you have active bleeding disorders or are taking blood thinners, consult your doctor as this medicine can increase bleeding risks.
  • Check the package: Always inspect the blister pack before use; do not take the medication if the foil is torn, broken, or if the tablets appear damaged.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (like warfarin): Taking these together can increase the risk of stomach bleeding.
  • Other NSAIDs or pain relievers: May increase the risk of stomach ulcers and kidney damage.
  • Certain blood pressure medications (like ACE inhibitors or diuretics): ENDOLIDE DT TABLET can reduce their effectiveness and increase the risk of kidney strain.
  • Ketoconazole or other liver-processed drugs: Can increase the risk of liver damage.

 

Drug-Food Interactions

  • Alcohol: Significantly increases the risk of severe liver toxicity and stomach bleeding.

 

Drug-Disease Interactions

  • Liver Disease: Can worsen existing liver impairment and cause severe liver damage.
  • Stomach Ulcers or GI Bleeding: May trigger or worsen internal bleeding and ulceration.
  • Kidney Impairment: Can reduce kidney blood flow, worsening renal function.
  • Asthma: May trigger asthma attacks or breathing difficulties in individuals sensitive to pain relievers.
Nimesulide + ParacetamolKetoconazole
Severe
Nimesulide + ParacetamolEthanol
Severe

Drug-Drug Interactions

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Nimesulide + ParacetamolKetoconazole
Severe
How does the drug interact with Endolide Dt Tablet:
Co-administration of Nimesulide and Paracetamol with Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nimesulide and Paracetamol with Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience joint pain or swelling, fever, vomiting, stomach pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
Nimesulide + ParacetamolEthanol
Severe
How does the drug interact with Endolide Dt Tablet:
Coadministration of Nimesulide and Paracetamol with Ethanol may increase the risk of liver damage.

How to manage the interaction:
Although Nimesulide and Paracetamol with Ethanol together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor immediately if you experience a fever, joint pain or swelling, vomiting, or yellowing of the skin or the whites of your eyes. Do not stop using any medications without talking to a doctor.
Nimesulide + ParacetamolTeriflunomide
Severe
How does the drug interact with Endolide Dt Tablet:
Co-administration of Teriflunomide with Nimesulide and Paracetamol may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Nimesulide and Paracetamol with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. You consult a doctor immediately if you have fever, joint pain or swelling, vomiting, abdominal pain, dark colored urine, yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
Nimesulide + ParacetamolLomitapide
Severe
How does the drug interact with Endolide Dt Tablet:
Co-administration of Lomitapide with Nimesulide and Paracetamol may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nimesulide and Paracetamol with Lomitapide, you can take these medicines together if prescribed by a doctor. Consult a doctor immediately if you experience fever, joint pain or swelling, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Nimesulide + ParacetamolMipomersen
Severe
How does the drug interact with Endolide Dt Tablet:
Co-administration of Mipomersen with Nimesulide and Paracetamol may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Nimesulide and Paracetamol with Mipomersen, but it can be taken if prescribed by a doctor. Call your doctor immediately if you experience fever, joint pain or swelling, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
Nimesulide + ParacetamolLeflunomide
Severe
How does the drug interact with Endolide Dt Tablet:
Co-administration of Nimesulide and Paracetamol with Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Nimesulide and Paracetamol with Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, joint pain or swelling, vomiting, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

ENDOLIDE DT TABLET is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.

ENDOLIDE DT TABLET works by blocking the effects of prostaglandins, chemicals that induce pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, ENDOLIDE DT TABLET helps relieve pain.

No, ENDOLIDE DT TABLET is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of a stomach ulcer or gastric bleeding. Do not take ENDOLIDE DT TABLET in this condition. It is better to inform your doctor if you experience stomach pain after ingesting this medication.

No, ENDOLIDE DT TABLET should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results, take it at the doses and for the duration advised by your doctor.

Yes, ENDOLIDE DT TABLET should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and upset.

You should not take ENDOLIDE DT TABLET if you have a history of peptic ulceration, a history of gastrointestinal haemorrhage, Crohn's disease or ulcerative colitis.

No, ENDOLIDE DT TABLET should not be taken if you plan to get pregnant, as it contains nimesulide, which may cause birth defects. So, before starting ENDOLIDE DT TABLET, please consult your doctor if you are pregnant or planning a pregnancy.

Though ENDOLIDE DT TABLET may be used for tooth pain, it should not be used in children unless advised by the doctor. Please consult the doctor before using ENDOLIDE DT TABLET in children; the doctor will prescribe appropriate medicine based on the child’s condition.

ENDOLIDE DT TABLET is a combination medication that belongs to the class of painkillers called non-steroidal anti-inflammatory drugs. It is mainly prescribed to treat pain and relieve discomfort caused by tooth pain, arthritis, period pain, and other types of short-term pain.

As ENDOLIDE DT TABLET is indicated for short-term pain relief, it can be discontinued once pain relief is achieved. However, it is advised to take ENDOLIDE DT TABLET for the prescribed duration to effectively treat your condition.

Taking ENDOLIDE DT TABLET may cause nausea and vomiting. If you feel sick, talk to your doctor or pharmacist for help. To cope with nausea and vomiting, take your medicine with food or milk, eat small meals, and stay hydrated. Avoid spicy foods and lying down after taking the medicine. Try ginger products like ginger tea or candies. If your symptoms are severe, ask your doctor for help.

Don't take ENDOLIDE DT TABLET if you're allergic to it or other painkillers, have stomach ulcers or bleeding, asthma, recent heart surgery, severe kidney or liver problems. Consult the doctor if you are pregnant or breastfeeding.

ENDOLIDE DT TABLET can be taken with vitamin B-complex if prescribed by your doctor. Please consult your doctor if you have any concerns.

ENDOLIDE DT TABLET may cause harm to the liver, especially if used for a longer duration or in higher doses. So, do not take a higher dose than the recommended dose of ENDOLIDE DT TABLET.

Taking more than the recommended dose of ENDOLIDE DT TABLET is dangerous. Overuse of ENDOLIDE DT TABLET can harm your liver and kidneys, which can be life-threatening. Always follow the dosage instructions as advised by the doctor.

ENDOLIDE DT TABLET should be stored in a cool, dry place away from sunlight. Keep away from children and pets.

Though ENDOLIDE DT TABLET may help lower body temperature, it is primarily used for pain relief. Consult your doctor before taking ENDOLIDE DT TABLET for fever or if you have any concerns.

Follow your doctor's advice and take the right amount of medicine. Inform your doctor about any health problems, allergies, or other drugs you're taking. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.

You are recommended to consult your doctor before taking other medications while using ENDOLIDE DT TABLET to avoid drug interactions.

If you suspect an overdose of ENDOLIDE DT TABLET, seek medical help immediately. Quick action can help prevent serious harm, so don’t wait to seek medical attention.

The common side effects of ENDOLIDE DT TABLET include loss of appetite, nausea, vomiting, abdominal pain, persistent tiredness, or dark or discoloured urine. Not everyone experiences the side effects above. If you experience any discomfort, speak with your doctor.

No, you should always take ENDOLIDE DT TABLET with or after food. Taking it on an empty stomach increases the risk of stomach irritation and indigestion. If you experience persistent stomach upset, talk to your doctor.

No, ENDOLIDE DT TABLET is designed for short-term pain relief. Daily use for chronic headaches can lead to serious risks, including liver damage and medication overuse headaches. If you have chronic headaches, talk to your doctor.

No, you should strictly avoid alcohol while taking ENDOLIDE DT TABLET. Alcohol combined with this medication heavily increases the risk of severe liver damage and stomach bleeding. For more safety advice, talk to your doctor.

ENDOLIDE DT TABLET is generally not recommended during pregnancy, especially during the third trimester, as it may harm the unborn baby or cause complications during delivery. If you are pregnant or planning to conceive, talk to your doctor.

Some people may experience mild dizziness or drowsiness as a side effect of ENDOLIDE DT TABLET. If you feel dizzy or sleepy after taking it, avoid driving or operating heavy machinery, and talk to your doctor.

You should exercise caution. ENDOLIDE DT TABLET can decrease the effectiveness of certain blood pressure drugs and increase the risk of kidney damage. Before combining them, talk to your doctor.

ENDOLIDE DT TABLET typically begins to relieve pain and reduce fever within 30 to 60 minutes of oral intake. If you do not feel any relief after a few doses, do not increase the dose; instead, talk to your doctor.

Stop taking ENDOLIDE DT TABLET immediately and seek medical attention. Skin itching, rashes, or blistering can be signs of a serious allergic reaction. For safe alternatives, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

205 Blue Star PlazaSarja Market, 2nd Floor Sector-7 Rohini East New Delhi-110065
Other Info - END0208

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