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Composition :

DOMPERIDONE-1MG/ML

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Endopace 1mg/ml Suspension

Endopace 1mg/ml Suspension is an antiemetic medicine. It is used to treat vomiting (being sick) in infants and children. Besides this, it also helps in the treatment of indigestion. In children, vomiting is a symptom of milk intolerance or food allergy.

Endopace 1mg/ml Suspension contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Endopace 1mg/ml Suspension cause dry mouth as a side effect in your child. If this side effect worsens, please consult your paediatrician. Endopace 1mg/ml Suspension should be given as advised by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Endopace 1mg/ml Suspension. However, if it does not resolve even after this, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of Endopace 1mg/ml Suspension to the child. Endopace 1mg/ml Suspension can be given with or without food. The dose of the medicine will be decided by your pediatrician depending upon the type and severity of the infection.

Endopace 1mg/ml Suspension is intended for paediatric use only. Avoid giving Endopace 1mg/ml Suspension to your child if she/he is allergic to any of the components present in the formulation. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, inform your child’s doctor about liver and kidney disease.

Uses of Endopace 1mg/ml Suspension

Endopace 1mg/ml Suspension is used in the treatment of vomiting. The detailed uses of Endopace 1mg/ml Suspension are as follows:<br/>• Nausea Relief: Endopace 1mg/ml Suspension helps alleviate nausea and vomiting in infants, making it easier for them to settle after feeding.<br/>• Digestive Aid: Endopace 1mg/ml Suspension supports healthy digestion by reducing gut discomfort, which can be beneficial for babies experiencing colic or gas.<br/>• Motion Sickness: Endopace 1mg/ml Suspension can be used to prevent or treat motion sickness in young children during travel.<br/>

Directions for Use

  • Endopace 1mg/ml Suspension should be administered 15 to 30 minutes before meals, or as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.
  • Shake well before use.

Medicinal Benefits

Endopace 1mg/ml Suspension contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time. If you're experiencing difficulty while nursing the child, your doctor may prescribe it if nothing else has helped.

How Endopace 1mg/ml Suspension Works

Endopace 1mg/ml Suspension contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Storage

Store in a cool and dry place away from sunlight
Side effects of Endopace 1mg/ml Suspension
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Endopace 1mg/ml Suspension

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Endopace 1mg/ml Suspension may include difficulty in speaking, disorientation, dizziness, fainting, irregular heartbeat, light-headedness, and loss of balance or muscle control. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid giving Endopace 1mg/ml Suspension to your child if she/he is allergic to any of the components present in the formulation. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your child’s doctor about liver and kidney disease. Endopace 1mg/ml Suspension is intended for paediatric use only. Hence, avoid using it for the adult population and pregnant women.

Drug-Drug Interactions

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DomperidoneHalofantrine
Severe

Drug-Drug Interactions

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How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Nefazodone can increase the blood levels of Endopace 1mg/ml Suspension.

How to manage the interaction:
There may be a possibility of interaction between Endopace 1mg/ml Suspension and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Endopace 1mg/ml Suspension and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Cisapride can increase the blood levels of Endopace 1mg/ml Suspension.

How to manage the interaction:
There may be a possibility of interaction between Endopace 1mg/ml Suspension and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Endopace 1mg/ml Suspension:
Coadministration of Endopace 1mg/ml Suspension with Ritonavir can increase the blood levels of Endopace 1mg/ml Suspension.

How to manage the interaction:
There may be a possibility of interaction between Endopace 1mg/ml Suspension and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Endopace 1mg/ml Suspension:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Endopace 1mg/ml Suspension and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • The child’s immune system is affected by stress and raises the risk of being sick. Hence try progressive muscle relaxation techniques to relieve stress.
  • Sleeping for 7-9 hours each night can make your child stay fit and safe.
  • Certain food items are known to cause vomiting in your child.
  • Make your child drink more fluids to avoid dehydration.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

Please consult your doctor if your child has a liver impairment or if you have any concerns regarding this.

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Kidney

Caution

Please consult your doctor if your child has a kidney impairment or if you have any concerns regarding this.

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Children

Safe if prescribed

Endopace 1mg/ml Suspension is safe for children above if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

Have a query?

FAQs

Endopace 1mg/ml Suspension is used to treat vomiting.

Endopace 1mg/ml Suspension contains domperidone which is a dopamine antagonist. It works by blocking certain receptors like dopamine and serotonin which stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.

If your child feels better, please consult your paediatrician before you stop giving Endopace 1mg/ml Suspension to your child.

Country of origin

India

Manufacturer/Marketer address

Depot. No. 8-1501/1D/5/6/7/13/14/169, Near Ukkad Police Station, Cotton Market, APMC Yard, Nehru Gunj,Kalaburagi(585104) Karnataka.
Other Info - EN30180

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