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Endyze Tablet is used to treat indigestion and bloating due to pancreatic problems. It contains Pancreatin and Dimethicone, which help in the digestion of food and facilitate the expulsion of gas through flatus or belching (burping). It may cause side effects such as nausea, stomach pain, diarrhoea, constipation, and bloating. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Endyze Tablet

Endyze Tablet is an oral medication used to manage digestive problems associated with pancreatic enzyme deficiency and excess gas in the digestive tract. It helps your body break down and absorb nutrients from food when the pancreas does not produce enough digestive enzymes. This medicine is commonly prescribed for conditions such as chronic pancreatitis, cystic fibrosis, pancreatic surgery, or other disorders that reduce pancreatic function. It also helps relieve symptoms such as bloating, flatulence, abdominal fullness, greasy stools, and discomfort after meals.

To get the best results, you should take Endyze Tablet consistently with every meal or snack, exactly as advised by your doctor. This medicine should be taken during or immediately after meals so the enzymes can mix properly with food during digestion. Making simple lifestyle adjustments, such as eating smaller portions and limiting highly fatty foods, may further improve symptom control.

While taking Endyze Tablet , some people may experience mild side effects such as stomach discomfort, nausea, constipation, diarrhoea, or mild skin irritation. These symptoms are usually temporary. However, consult your doctor immediately if you develop severe abdominal pain, sudden joint swelling, severe allergic reactions, or persistent digestive symptoms.

Talk to your doctor before starting Endyze Tablet if you have a history of gout, high uric acid levels, kidney disease, or pancreatic disorders. This medicine should generally not be used during episodes of acute pancreatitis or sudden worsening of chronic pancreatitis unless specifically recommended by your doctor. Do not take this medicine if you are allergic to pork proteins or any of the ingredients in this formulation.

Certain medications, including some antacids and nutritional supplements, may affect the effectiveness of this medicine. If you are pregnant, breastfeeding, caring for a child, or an older adult, consult your doctor before using Endyze Tablet .

Uses of Endyze Tablet

Endyze Tablet is used in the treatment of pancreatic insufficiency (pancreatin enzyme deficiency), bloating, and indigestion. The detailed uses of Endyze Tablet are as follows:

  • Pancreatic insufficiency: It helps digest fats, proteins, and carbohydrates when your pancreas is not producing enough natural digestive enzymes.
  • Flatulence and bloating: It relieves trapped gas and reduces stomach swelling, fullness, or tightness.
  • Dyspepsia: It eases painful or uncomfortable digestion, acid indigestion, and heaviness after eating.

Key Benefits

Endyze Tablet helps improve digestion and nutrient absorption in people who have difficulty breaking down food properly. It also helps relieve discomfort caused by excess gas, supporting better digestive health and overall well-being. Benefits may include:

  • Helps improve the digestion of fats, proteins, and carbohydrates.
  • Supports better absorption of essential nutrients from food.
  • May help prevent nutritional deficiencies, unintended weight loss, and fatigue associated with poor digestion.
  • Provides relief from bloating, abdominal fullness, and stomach discomfort caused by trapped gas.
  • Helps reduce excess gas and abdominal pressure.
  • Promotes greater digestive comfort and improved quality of life.

Directions for Use

Please follow these instructions carefully for safe and effective use:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or hold the tablet in your mouth, as this can cause severe irritation to your gums and cheeks.
  • Always take Endyze Tablet during or immediately after your meals or snacks.
  • Do not change your dose without consulting your healthcare provider.

Always follow your doctor's exact instructions regarding how and when to take Endyze Tablet .

How Endyze Tablet Works

Endyze Tablet contains Pancreatin and Dimethicone. • Pancreatin: It helps digest fats, proteins, and carbohydrates from food, allowing the body to absorb nutrients more effectively. This supports healthy digestion and helps relieve symptoms caused by digestive enzyme deficiency. • Dimethicone: It helps break up trapped gas in the stomach and intestines, making it easier for the body to remove it. This helps reduce bloating, abdominal fullness, and discomfort caused by excess gas.
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Alcohol

Caution

It is unknown whether alcohol interacts with Endyze Tablet . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Endyze Tablet belongs to pregnancy category C. Consult your doctor before taking Endyze Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Endyze Tablet passes into breast milk. Consult your doctor before taking Endyze Tablet ; your doctor will decide whether Endyze Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Endyze Tablet does not affect your ability to drive. However, Endyze Tablet may cause dizziness. So, do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Endyze Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Endyze Tablet if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Endyze Tablet can be given to children if prescribed by the doctor. The dose depends upon the child’s age and body weight.

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Heart

Safe if prescribed

Endyze Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Safe if prescribed

Endyze Tablet can be safely given in elderly patients if recommended by the physician.

What if I have taken an overdose of Endyze Tablet

If you take too much of this medicine, you may experience severe diarrhoea, abdominal pain, nausea, vomiting, or increased uric acid levels in the blood. Seek immediate medical attention. Contact your doctor, visit the nearest emergency department, or call emergency services (112 in India) if symptoms are severe. You may also contact a poison control centre or local emergency medical service for further guidance.

Diet & Lifestyle Advise

  • Eat smaller, frequent meals: Choose smaller meals throughout the day instead of three large meals to reduce the workload on your digestive system and improve comfort.
  • Limit fatty and fried foods: Avoid high-fat, fried, or greasy foods, as they can be harder to digest and may worsen bloating and digestive discomfort.
  • Identify trigger foods: Keep a food diary to track foods that cause gas and bloating, such as beans, cabbage, or carbonated drinks, and try to limit them if they trigger symptoms.
  • Stay well hydrated: Drink plenty of water throughout the day, especially if you experience loose stools, to help maintain proper hydration.
  • Maintain an upright posture after meals: Sit upright while eating and remain upright for at least 30 minutes after meals to support healthy digestion.

Have a query?

How Soon It Starts Working

  • The time required for Endyze Tablet to start to work: The time required for Endyze Tablet to show its action is unknown.
  • The time for which the effects of Endyze Tablet last: The duration of action for Endyze Tablet is unknown.

What if you forget to take Endyze Tablet

If you miss a dose of Endyze Tablet , take it as soon as you remember with your next meal or snack. If you are not eating, skip the missed dose and return to your normal schedule with your next meal. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the medicine before use: Do not take the tablets or capsules if the packaging is damaged or if they appear discolored, broken, or altered.
  • Swallow the medicine as directed: Never chew or crush enteric-coated tablets or capsules, as this may irritate the mouth and reduce the effectiveness of the treatment.
  • Take each dose with plenty of water: Always drink a full glass of water when taking this medicine to help ensure proper swallowing.
  • Consult a healthcare professional before switching brands: Different digestive enzyme products may contain different enzyme strengths, so seek medical advice before changing formulations.
  • Monitor your symptoms regularly: Contact your doctor if your digestive symptoms do not improve, worsen, or if you experience persistent weight loss, greasy stools, abdominal pain, or nutritional concerns.
  • Attend regular follow-up appointments: Regular reviews may be needed to ensure your enzyme dose remains appropriate and continues to control your symptoms effectively.
  • Use with special care in certain populations: Children with pancreatic enzyme deficiency, particularly those with cystic fibrosis, should use this medicine under pediatric supervision with an individualized dose. Older adults may require regular monitoring to maintain adequate nutrition and symptom control. During pregnancy or breastfeeding, use this medicine only if recommended by your healthcare provider after assessing the potential benefits and risks.

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Drug-Drug Interactions

  • Iron supplements: Taking Endyze Tablet at the same time as iron tablets may lower the amount of iron your body absorbs.
  • Antacids (calcium, magnesium): These can decrease the effectiveness of the digestive enzymes in Endyze Tablet .
  • Vitamin supplements (Folic acid): This medicine may reduce the absorption of folic acid, potentially leading to lower folate levels in your body.

Drug-Food Interactions

  • Alcohol: Drinking alcohol can irritate your stomach lining and significantly reduce the effectiveness of this digestive medication.

Drug-Disease Interactions

  • Gout or High Uric Acid Levels: Use this medicine with caution, as high doses of pancreatin may increase uric acid levels and worsen gout symptoms in susceptible individuals.
  • Acute Pancreatitis: This medicine is generally not recommended during acute pancreatitis or sudden flare-ups of chronic pancreatitis unless specifically advised by a healthcare professional.
  • Fibrosing Colonopathy: Very high doses of pancreatin have been associated with a rare condition called fibrosing colonopathy, which causes narrowing of the bowel. This risk has been reported primarily in patients with cystic fibrosis receiving high-dose pancreatic enzyme therapy.

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Habit Forming

No

Therapeutic Class

[ENZYMES]

FAQs

Endyze Tablet is used to treat pancreatic insufficiency (pancreatin enzyme deficiency), bloating, and indigestion.
Endyze Tablet might interfere with the absorption and reduce the effectiveness of folic acid and iron. To prevent this, maintain a minimum gap between both.
Mild loose stools can occasionally occur during treatment. However, severe, persistent, or watery diarrhea should be evaluated by a healthcare professional. Contact your doctor promptly if this occurs. Do not stop, restart, or change your prescribed treatment without medical advice, especially if you rely on pancreatic enzyme replacement therapy for proper digestion and nutrient absorption.
To treat your condition effectively, continue taking Endyze Tablet for as long as your doctor has prescribed it. Many patients will need to take Endyze Tablet for the rest of their lives. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Endyze Tablet .
The side effects of Endyze Tablet may include nausea, stomach pain, diarrhoea, constipation, and bloating. In most cases, these side effects are mild and temporary and resolve on their own over time. However, if you experience persistent or severe side effects, it's essential to consult your doctor for proper evaluation and guidance.
Endyze Tablet can help with digestion and relieve symptoms like indigestion and bloating. If you have liver disease, it's always best to consult with your doctor before taking Endyze Tablet , and they'll provide personalized guidance on using it safely.
Creon and Endyze Tablet are both pancreatic enzyme supplements used to treat pancreatic insufficiency, but they differ in their composition and formulation.
Endyze Tablet is a combination of two drugs: pancreatin (digestive enzyme) and Dimethicone (anti-flatulent). Pancreatin contains ‘pancreatin enzymes’ that break down food and convert it into energy. On the other hand, Dimethicone decreases the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping).
Endyze Tablet is generally safe when taken as directed by your healthcare provider. It treats indigestion and bloating effectively by aiding fat digestion and reducing stomach gas. To ensure safety, be sure to follow your doctor's dosage and duration guidelines, monitor yourself for unusual side effects, and consult your doctor if you experience any concerns.
Endyze Tablet should be stored at room temperature, below 30°C, and kept out of reach of children. Always follow the storage instructions provided on the packaging or by your healthcare provider.
No, you should not take Endyze Tablet on an empty stomach. This medicine requires food to work, as its active ingredients help digest the meals you eat. Taking it without food can also cause stomach irritation. Talk to your doctor if you are unsure about when to take it.
No, you must swallow Endyze Tablet whole with a glass of water. Chewing, crushing, or breaking the tablet can destroy the protective coating, making the medicine less effective and causing severe mouth irritation or ulcers. Talk to your doctor or pharmacist if you have trouble swallowing tablets.
The safety of Endyze Tablet during pregnancy has not been fully established. If you are pregnant or planning to become pregnant, you should only take this medicine if your healthcare provider clearly deems it necessary. Talk to your doctor to weigh the benefits and potential risks.
Endyze Tablet starts working as soon as it reaches your stomach and mixes with your food, typically within a few minutes of eating. It provides rapid relief from gas and assists with digesting that specific meal. Talk to your doctor if you do not notice any improvement after a few days.
It is best to avoid or limit alcohol while taking Endyze Tablet . Alcohol can irritate your digestive tract, worsen symptoms like bloating and indigestion, and interfere with how well the medicine works. Talk to your doctor about safe alcohol limits for your condition.
Some antacids containing calcium carbonate or magnesium hydroxide can reduce the effectiveness of Endyze Tablet . If you need to use antacids, it is best to space them out from your dose of Endyze Tablet . Talk to your doctor or pharmacist for a safe schedule.
High doses of digestive enzymes can sometimes cause uric acid levels to rise in the blood, which may trigger joint pain or gout-like symptoms. If you experience unusual joint pain or swelling, contact your healthcare provider right away. Talk to your doctor for further guidance.

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Country of origin

INDIA

Manufacturer/Marketer address

205 Blue Star PlazaSarja Market, 2nd Floor Sector-7 Rohini East New Delhi-110065
Other Info - END0160
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