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Enfergab Gel is a combination medicine used to manage neuropathic pain caused by damaged nerves. This medicine blocks pain signals from nerves to the brain, thus relaxing muscles to relieve pain and discomfort. You may experience common side effects like itching, irritation, redness, and a burning sensation at the application site. It is a topical medication. Avoid contact with eyes, ears, nose, and mouth.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Enfergab Gel

Enfergab Gel is a prescription-strength topical gel designed to target localised nerve discomfort and associated muscle tightness. It is primarily used to treat neuropathic pain conditions, such as post-herpetic neuralgia and diabetic nerve pain, directly at the source. This medication helps soothe overactive nerves and relax muscles in a specific, localised area of your body.

For the best results, you must apply Enfergab Gel consistently at the same times every day as directed by your doctor. Regular use helps maintain an even level of the active ingredients in your skin and underlying tissues to provide steady relief. Always apply this gel to clean, dry, and unbroken skin, and combine it with gentle, daily physical stretching to support muscle flexibility.

While using this topical gel, you may experience mild local skin reactions like slight redness, itching, or a temporary warm sensation. These mild symptoms usually go away on their own as your skin adapts to the medication. However, if you develop severe blistering, a widespread rash, or experience unusual drowsiness, stop using the product and contact your doctor immediately.

Before applying Enfergab Gel, talk to your doctor if you have a history of kidney disease, liver damage, or highly sensitive skin. Do not use this medicine if you have known allergies to any of its individual ingredients or if the target skin area is infected, broken, or severely burned. It should also be avoided on large surface areas of skin unless specifically cleared by a healthcare professional.

Although systemic absorption is minimal, using this gel alongside oral sedatives or alcohol can increase your risk of feeling sleepy or lightheaded. If you are pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist before starting treatment to ensure it is safe for your situation.
 

Uses of Enfergab Gel

Enfergab Gel is used to treat neuropathic pain conditions. The detailed uses of Enfergab Gel are as follows:

  • Neuropathic pain: Enfergab Gel helps ease burning, tingling, or shooting pain caused by damaged or oversensitive nerves.
  • Muscle spasms: It relaxes tight, painful muscles in the localised area where the gel is applied.
  • Post-herpetic neuralgia: It calms the persistent, sharp nerve pain that can remain after a shingles outbreak.
  • Diabetic neuropathy: It provides targeted relief for localised nerve discomfort often felt in the hands or feet.
     

Key Benefits

Enfergab Gel provides targeted relief from localized muscle and joint pain by delivering the medicine directly to the affected area. With regular use as directed, it helps reduce pain, improve mobility, and support comfortable daily movement with minimal systemic exposure.

  • Provides Targeted Pain Relief: Applied directly to the affected area, this medicine helps relieve localized pain, muscle tightness, and discomfort, allowing you to move more comfortably.
  • Minimises Whole-Body Side Effects: Because the gel acts mainly at the site of application, very little medicine enters the bloodstream, reducing the likelihood of systemic side effects such as drowsiness, dizziness, or stomach irritation.
  • Improves Mobility and Recovery: By easing pain and stiffness, this medicine helps improve joint movement, supports participation in physical therapy, and promotes better sleep by reducing discomfort.

Directions for Use

  • Follow your doctor's guidance regarding the dosage and timing for optimal results.
  • Take a small amount on your fingertip and apply it as a thin layer on the clean and dry affected area as prescribed by your doctor.
  • Avoid contact of Enfergab Gel with the nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly.
  • Wash your hands before and after using Enfergab Gel if your hands are not the affected area to prevent the spread of infection.

How Enfergab Gel Works

Enfergab Gel combines three active ingredients that work together in different ways to target nerve pain and muscle spasms at the application site. Baclofen is a muscle relaxant. It works by blocking excess nerve signals in the spinal cord that cause muscles to spasm and tighten, helping to relax the affected muscle tissue and improve local movement. Gabapentin targets hypersensitive nerve pathways. It stabilises electrical activity in damaged or irritated nerves, reducing the transmission of pain signals to the brain and calming uncomfortable sensations like burning or tingling. Lidocaine is a local anaesthetic. It temporarily blocks pain signals at the skin level by stopping sodium from entering nerve endings, providing rapid numbing and localised relief from surface pain.
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Alcohol

Caution

Consuming alcohol along with Enfergab Gel is not advisable as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

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Pregnancy

Caution

Limited information is available regarding the usage of Enfergab Gel during pregnancy. Please inform your doctor before using Enfergab Gel if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available regarding the usage of Enfergab Gel during lactation. Inform your doctor before using Enfergab Gel if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

It is not known if Enfergab Gel alters your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Please inform your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please inform your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Limited information is available regarding the usage of Enfergab Gel in children, so please consult a doctor if you have any concerns.

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Heart

Caution

Let your doctor know if you have any history of heart problems. Your doctor will weigh the benefits and potential risks before prescribing Enfergab Gel.

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Geriatrics

Caution

Please consult your doctor before using Enfergab Gel in elderly patients, as it may increase the risk of side effects.

What if I have taken an overdose of Enfergab Gel

Because this is a topical medicine, an accidental overdose from skin application is rare. However, if someone accidentally swallows the gel, or if you apply far too much and experience severe dizziness, slow breathing, or extreme drowsiness, seek immediate medical attention.

Diet & Lifestyle Advise

  • Stay active with gentle movement: Engaging in low-impact activities like walking, swimming, or gentle stretching can help keep muscles flexible and reduce nerve sensitivity.
  • Manage blood sugar levels: If your nerve pain is linked to diabetes, maintaining stable blood sugar through a balanced diet can help prevent further nerve damage.
  • Avoid extreme temperatures: Keep the treated skin away from direct heat sources like heating pads or hot tubs, as heat can increase the absorption of the medicine and raise the risk of side effects.
  • Stay hydrated: Drinking enough water throughout the day helps maintain muscle function and may reduce the frequency of muscle cramps.
  • Wear loose clothing: Wear soft, loose-fitting cotton clothing over the treated area to prevent friction and skin irritation.
     
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How Soon It Starts Working

The time required for Enfergab Gel to start to work: Enfergab Gel effect lasts for 15 to 30 minutes of administration. The time for which the effects of Enfergab Gel last: Enfergab Gel effect lasts for 4 to 6 hours.

What if you forget to take Enfergab Gel

If you forget to apply a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply a double amount to make up for a missed one.

Storage

• Store Enfergab Gel at room temperature, safely between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your skin first: Always inspect the skin before application; never apply the gel to open wounds, cuts, scrapes, or infected areas.
  • Wash your hands: Thoroughly wash your hands with soap and water immediately after applying the gel to avoid accidentally transferring it to your eyes or mouth.
  • Avoid heat sources: Do not use heating pads, hot water bottles, or take hot showers immediately after applying the gel, as heat can cause too much medication to enter your system.
  • Monitor for skin reactions: If you notice worsening redness, scaling, or a rash at the application site, stop using the gel and consult your doctor.
  • Avoid wrapping the area: Leave the treated area uncovered or wear loose clothing; do not bandage it tightly, as this can increase drug absorption.
  • Do not share: This medication is customised for your specific nerve and muscle pain; do not share it with others even if they have similar symptoms.

verifiedApollotooltip
  • Oral muscle relaxants or sedatives: Using these alongside Enfergab Gel may slightly increase the risk of drowsiness or sleepiness.
  • Other local anaesthetics: Combining this gel with other medications containing numbing agents can increase the risk of local skin toxicity or systemic absorption issues.
  • Class I antiarrhythmic medicines: Use caution if you are taking heart rhythm medications, as they may interact with the lidocaine component if absorbed into your system.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Enfergab Gel when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS TOPICAL]

FAQs

Enfergab Gel is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic, progressive nerve condition in which the neurological system is injured or malfunctioning, resulting in nerve pain.
Enfergab Gel contains Baclofen, Gabapentin, and Lidocaine. Baclofen relieves pain and discomfort by relaxing muscles. Gabapentin binds to a specific site on voltage-gated calcium channels. Lidocaine prevents pain signals from reaching the brain. Together, Enfergab Gel aids in relieving neuropathic pain.
Avoid concomitant use of Enfergab Gel with other topical products such as cosmetics, sunscreens, lotions, moisturisers, insect repellent creams, and other gels. Maintain a gap of 30minutes between Enfergab Gel and other topical products.
Continue using Enfergab Gel for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience difficulty while using Enfergab Gel.
Please seek medical advice before using any oral analgesic medications along with Enfergab Gel. In some cases, based on your medical condition and response to the treatment, your doctor may prescribe both oral and topical medications to subsidise the pain.
You are recommended to take a shower, bathe or wash the treated area of skin after 1 hour of applying Enfergab Gel for effective results.
Yes, Enfergab Gel may cause skin irritation at the application site as a common side effect. It is not necessary for everyone using Enfergab Gel to experience this side effect. However, if the irritation persists or worsens, please consult a doctor.
No, you should not use heating pads, hot water bottles, or heat lamps over the treated area. Heat increases blood flow to the skin, which can cause your body to absorb too much of the medication too quickly, increasing the risk of serious side effects. Talk to your doctor if you need advice on safe heat therapy.
The safety of this topical combination during pregnancy or breastfeeding has not been fully established. Because small amounts of the active ingredients can be absorbed through the skin, you should talk to your doctor to weigh the potential benefits against any risks before using this medication.
If the gel gets into your eyes, nose, or mouth, rinse the area immediately and thoroughly with large amounts of cool, clean water. If you experience persistent burning, pain, or vision changes after rinsing, seek medical help right away. Talk to your doctor if you have concerns about accidental exposure.
You should avoid covering the treated skin with tight bandages, plastic wrap, or airtight dressings. Doing so can wrap the medication against the skin and increase absorption into your bloodstream, which may lead to unwanted side effects. If you need to protect the area, use loose, breathable clothing and talk to your doctor.
Because Enfergab Gel is applied topically, only a very small amount of the medication enters your bloodstream, making systemic side effects like drowsiness uncommon. However, some sensitive individuals, or those applying the gel over very large areas, may feel mild drowsiness. If you experience severe sleepiness, stop using it and talk to your doctor.
While systemic absorption of this topical gel is low, it is best to limit or avoid alcohol while using medications that affect the nervous system or muscles. Alcohol can enhance potential side effects like drowsiness or dizziness. Talk to your doctor or pharmacist about safe alcohol consumption during your treatment.
The application frequency depends entirely on your specific condition and your doctor's recommendation. You should never apply this medication more often or in larger amounts than prescribed on your label. Talk to your doctor or pharmacist if you feel your current schedule is not managing your pain effectively.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Manufacturer/Marketer address

201, Iscon Mall, Above Stat India Bazar, Satellite, Ahmedabad-380015.
Other Info - EN89015
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