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  1. Home
  2. Medicine

  3. Entodase Inj 1500 Iu

Prescription drug
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Entodase Inj 1500 Iu, Pack of 1 Injection
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Extra 15% Off with Bank Offers

Composition :

HYALURONIDASE-1500IU

Manufacturer/Marketer :

Entod Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Entodase Inj 1500 Iu

Entodase Inj 1500 Iu belongs to a class of an enzyme primarily used together with fluids injected into the body to treat dehydration. It is also used to aid in the absorption of injections that are given into a muscle or under the skin. It is also used to enable excess fluids and blood in the tissues to be more easily re-absorbed. Besides this, it is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.

Entodase Inj 1500 Iu contains Hyaluronidase is an enzyme, a natural spreading or diffusing substance that activates processes in the body. It works by increasing the permeability of connective tissue through hyaluronic acid hydrolysis (a chemical substance that retains water to keep your tissues well-lubricated and moist). It is used to temporarily break down the natural barriers in the body tissues so that injections or fluids injected under the skin or into muscle are more easily spread and absorbed.

Entodase Inj 1500 Iu will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as hormone imbalance, allergic reaction, slow growth in children and teenagers, angioedema (swelling of deeper layers of skin), dizziness, injection site reaction, edema (swelling). Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not take Entodase Inj 1500 Iu if you are allergic to Hyaluronidase or any other contents present in it. Do not take Entodase Inj 1500 Iu if you are pregnant or breastfeeding unless prescribed. Care should be taken in children and elderly patients to control the speed, and total volume of fluid administered and avoid over-hydration, especially in renal impairment. It is unknown if Entodase Inj 1500 Iu alters your ability to drive, so be cautious while driving or operating machinery. Consult your doctor before consuming alcohol, along with Entodase Inj 1500 Iu. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Entodase Inj 1500 Iu

Entodase Inj 1500 Iu is used to Enhance the absorption and dispersion of injected drugs, Hypodermoclysis, Subcutaneous urography. The detailed uses of Entodase Inj 1500 Iu are as follows:

  • Enhancing absorption of injected medications: Entodase Inj 1500 Iu helps improve the dispersion and uptake of other drugs administered under the skin or into muscle, making treatments more effective and faster-acting.
  • Facilitating fluid replacement therapy: Entodase Inj 1500 Iu is used with subcutaneous fluids to treat dehydration when intravenous access is difficult, allowing better distribution of fluids through tissues.
  • Improving visibility in diagnostic imaging: By increasing tissue permeability, Entodase Inj 1500 Iu aids the absorption of contrast agents used in procedures like subcutaneous urography, helping produce clearer imaging results.
  • Supporting cosmetic and emergency procedures: Entodase Inj 1500 Iu is used to dissolve hyaluronic acid-based dermal fillers in aesthetic treatments and to assist in emergency drug delivery when veins are inaccessible.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Entodase Inj 1500 Iu will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer.

Medicinal Benefits

Entodase Inj 1500 Iu contains Hyaluronidase is an enzyme, a natural spreading or diffusing substance that activates processes in the body. It works by increasing the permeability of connective tissue through hyaluronic acid hydrolysis (a chemical substance that retains water to keep your tissues well lubricated and moist). It is used to temporarily break down the natural barriers in the body tissues so that injections or fluids injected under the skin or into muscle are more easily spread and absorbed. Entodase Inj 1500 Iu is also used to enable excess fluids and blood in the tissues to be more easily reabsorbed and help contrast dyes in your body show more clearly on certain types of x-rays or scans.

How Entodase Inj 1500 Iu Works

Entodase Inj 1500 Iu contains Hyaluronidase is an enzyme, a natural spreading or diffusing substance that activates processes in the body. It works by increasing the permeability of connective tissue through hyaluronic acid hydrolysis (a chemical substance that retains water to keep your tissues well-lubricated and moist). It is used to temporarily break down the natural barriers in the body tissues so that injections or fluids injected under the skin or into muscle are more easily spread and absorbed.

Storage

• Store in a cool and dry place away from sunlight.• Keep Entodase Inj 1500 Iu out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Entodase Inj 1500 Iu

Since Entodase Inj 1500 Iu is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Entodase Inj 1500 Iu should not be injected into a vein (as an intravenous injection) because the enzyme is rapidly inactivated. If you have had cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes, inform your doctor before taking Entodase Inj 1500 Iu. Use with caution in children and elderly patients. Inform your doctor before taking Entodase Inj 1500 Iu if you are pregnant or are nursing. Consumption of alcohol should be avoided during the treatment with Entodase Inj 1500 Iu as it may lead to increased risk of liver damage. Entodase Inj 1500 Iu should not be used for anesthetic procedures in cases of unexplained premature labor. Also, it should not be injected into or around an infected or inflamed area because of the danger of spreading a localized infection.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Entodase Inj 1500 Iu Substitute

Substitutes safety advice
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Alcohol

Caution

It is unknown if alcohol interacts with Entodase Inj 1500 Iu. Please consult your doctor before consuming alcohol, along with Entodase Inj 1500 Iu.

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Pregnancy

Caution

Entodase Inj 1500 Iu is pregnancy category C drug. It can only be injected in pregnant women if suggested by the doctor as the safety and effectiveness of Entodase Inj 1500 Iu has not been established.

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Breast Feeding

Caution

Entodase Inj 1500 Iu can only be injected in breastfeeding women when suggested by the doctor as safety and effectiveness of Entodase Inj 1500 Iu has not been established.

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Driving

Caution

In some cases, Entodase Inj 1500 Iu may cause dizziness and drowsiness. So if you observe such symptoms, immediately consult your doctor.

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Liver

Caution

Entodase Inj 1500 Iu can only be injected in persons dealing with liver disease if prescribed by a doctor.

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Kidney

Caution

Entodase Inj 1500 Iu can only be injected in persons dealing with kidney disease if prescribed by a doctor.

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Children

Caution

Entodase Inj 1500 Iu can be used in children only when prescribed by a doctor.

FAQs

Entodase Inj 1500 Iu is used together with fluids injected into the body to treat dehydration. It is also used to aid in the absorption of injections and enable excess fluids and blood in the tissues to be more easily re-absorbed. Besides this, it is also used to help contrast dyes in the body show more clearly on certain types of X-rays or scans.

Entodase Inj 1500 Iu contains Hyaluronidase, an enzyme that increases the permeability of connective tissue through the hydrolysis of hyaluronic acid and increases the diffusion of injected fluids or localized transudates exudates, thus facilitating their absorption.

Do not try to take injections on your own. Entodase Inj 1500 Iu has to be given by the registered medical practitioner (RMP) or doctor.

Yes, Entodase Inj 1500 Iu can cause dizziness in some patients. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

The common side-effects of Entodase Inj 1500 Iu are allergic reaction, hormone imbalance, slow growth in children and teenagers, angioedema (swelling of deeper layers of skin), dizziness, injection site reaction, and oedema (swelling).

A person of age 65 or older should use Entodase Inj 1500 Iu with caution, as directed by the doctor, as the chances of side effects increase in older people.

Country of origin

India

Manufacturer/Marketer address

Ashirwad building, S.V.Road, Opp. Badi Masjid, Bandra(W), Mumbai-400050, INDIA
Other Info - ENT0126

Disclaimer

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 3:14 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/hyaluronidase-injection.html
  2. https://www.medicines.org.uk/emc/files/pil.1505.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021716lbl.pdf

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