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  3. Eporen 4000 Pfs I.U Inj

Eporen 4000 Pfs I.U Inj, Pack of 1 INJECTION
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Composition :

RECOMBINANT HUMAN ERYTHROPOIETIN ALFA-4000IU

Manufacturer/Marketer :

Abl Biotechnologies Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Eporen 4000 Pfs I.U Inj

Eporen 4000 Pfs I.U Inj belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders, and those due to undergo major bone surgery. Anaemia refers to low blood counts due to a deficiency of the blood component haemoglobin, resulting in a reduced oxygen-carrying capacity of the blood.

Eporen 4000 Pfs I.U Inj contains Recombinant Human Erythropoietin Alfa, which works by stimulating the bone marrow to produce more red blood cells, thereby correcting low blood counts and anaemia.

In some cases, Eporen 4000 Pfs I.U Inj may cause specific common side effects such as vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects consistently.

Please inform the doctor of your detailed medical history, including hypertension, heart disease, heart attack, stroke, epilepsy, cancer, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Consult your doctor before taking Eporen 4000 Pfs I.U Inj during pregnancy and nursing. Store this medicine at 2°C-8°C. Do not freeze.

Uses of Eporen 4000 Pfs I.U Inj

Eporen 4000 Pfs I.U Inj is used to treat anemia caused by chronic kidney illness, cancer, and HIV infection. The detailed uses of Eporen 4000 Pfs I.U Inj are as follows:<br/>• Anemia due to Chronic Kidney Disease (CKD): Eporen 4000 Pfs I.U Inj helps correct anemia in patients with CKD, especially those on dialysis, by replacing the deficient natural erythropoietin.<br/>• Anemia from Chemotherapy: Eporen 4000 Pfs I.U Inj is used in cancer patients undergoing chemotherapy to reduce the need for blood transfusions.<br/>• Pre-surgical Use: Eporen 4000 Pfs I.U Inj sometimes given before major elective surgeries (like orthopedic procedures) to reduce the need for transfusions.<br/>• HIV-related Anemia: Eporen 4000 Pfs I.U Inj is used in patients receiving zidovudine (AZT), which can suppress bone marrow function.<br/>

Directions for Use

• It is usually injected one to three times weekly. However, follow your doctor's instructions regarding dosage and timing of Eporen 4000 Pfs I.U Inj for better results.• Eporen 4000 Pfs I.U Inj may be given by a doctor/nurse, or you may be told to inject the medication at home. In that case, a healthcare provider will show you how to inject the medication. Be sure that you understand the directions and use it exactly as advised.• Rotate the injection site each time. Do not inject into a spot that is tender, red, bruised, hard, or has scars or stretch marks.

Medicinal Benefits

Eporen 4000 Pfs I.U Inj is a blood hormone. It contains Recombinant Human Erythropoietin Alfa used to treat anaemia caused by chronic diseases and anaemia related to kidney disease, cancers, bone marrow disorders, chemotherapy, children and adults on dialysis, and in those due to undergo major bone surgery. Eporen 4000 Pfs I.U Inj stimulates the bone marrow to produce more red blood cells. In addition, it also corrects any dysregulated erythropoiesis (RBC formation) and remedies the formation of any defunct precursors of RBC’s, paving the way for healthy red blood cell production. Clinically, Eporen 4000 Pfs I.U Inj causes a direct increase in haemoglobin values and reduces the rates and requirement of blood transfusion.

How Eporen 4000 Pfs I.U Inj Works

Eporen 4000 Pfs I.U Inj contains Recombinant Human Erythropoietin Alfa that works by stimulating the bone marrow to produce more red blood cells, thereby correcting any low blood counts and anaemia.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Eporen 4000 Pfs I.U Inj

Overdose of Eporen 4000 Pfs I.U Inj increases blood viscosity and the risk of thrombosis by raising haemoglobin levels to dangerously high levels. Seek immediate medical help if you get an overdose of this medicine.

Drug Warnings

Inform the doctor if you have an allergy to any of its components. Proceed with caution in case of a latex allergy. Please inform the doctor of your detailed medical history, including hypertension, heart disease, myocardial infarction, stroke, epilepsy, head and neck cancers, liver disease, thromboembolism, porphyria and/or pure red cell aplasia (where the bone marrow cannot produce enough RBCs). Inform your doctor of any medicines you may be taking especially if you are on any immunosuppressants, blood thinners or blood stimulants. Please consult your doctor before taking Eporen 4000 Pfs I.U Inj during pregnancy and nursing.

Drug-Drug Interactions

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ErythropoietinThalidomide
Severe
ErythropoietinPomalidomide
Severe

Drug-Drug Interactions

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ErythropoietinThalidomide
Severe
How does the drug interact with Eporen 4000 Pfs I.U Inj:
Taking thalidomide with Eporen 4000 Pfs I.U Inj may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Eporen 4000 Pfs I.U Inj and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Eporen 4000 Pfs I.U Inj:
Pomalidomide can cause serious blood clots and taking it alongside Eporen 4000 Pfs I.U Inj may enhance the risk.

How to manage the interaction:
Co-administration of Eporen 4000 Pfs I.U Inj with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Eporen 4000 Pfs I.U Inj:
Carfilzomib can cause serious blood clots and taking it alongside Eporen 4000 Pfs I.U Inj may enhance the risk.

How to manage the interaction:
Co-administration of Eporen 4000 Pfs I.U Inj with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinLenalidomide
Severe
How does the drug interact with Eporen 4000 Pfs I.U Inj:
Combining Eporen 4000 Pfs I.U Inj with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Eporen 4000 Pfs I.U Inj and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • As nausea and vomiting may occur using Eporen 4000 Pfs I.U Inj, make sure to take it on light, small meals. 
  • To promote blood production, eat red fruits and vegetables, such as apples, pomegranates, dry fruits, beans, and nuts.
  • Avoid caffeine and alcohol as these can precipitate bleeding.
  • Take care of your mental health. Stress is a huge factor that can cause excessive bleeding. Make sure you meditate daily in the morning.
  • Yoga has also proven very effective in preventing excessive blood loss. The butterfly pose is one of the best poses for treating heavy periods.
  • Make sure you drink a lot of water and keep yourself hydrated. Fluid intake helps flush out toxins.

Habit Forming

No

Therapeutic Class

BLOOD DERIVATIVES

Eporen 4000 Pfs I.U Inj Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

There is not enough literature to explain the effects of alcohol. Consult your doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning to become pregnant, inform your doctor. Your doctor will weigh the benefits against the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Eporen 4000 Pfs I.U Inj; your doctor will decide whether breastfeeding mothers can use Eporen 4000 Pfs I.U Inj or not.

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Driving

Caution

It's unclear whether Eporen 4000 Pfs I.U Inj affects driving abilities, so don't drive or operate machinery if you're having trouble concentrating or reacting.

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Liver

Caution

Eporen 4000 Pfs I.U Inj should be used with caution in patients suffering from liver diseases. Please inform your doctor before receiving it.

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Kidney

Caution

Eporen 4000 Pfs I.U Inj should be used with caution in patients suffering from kidney diseases. Please inform your doctor before receiving it.

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Children

Safe if prescribed

Eporen 4000 Pfs I.U Inj can be used in children in prescribed paediatric doses.

Have a query?

FAQs

Eporen 4000 Pfs I.U Inj belongs to the group of hormones used in the treatment of chronic anaemia and anaemic states seen in kidney disease, cancers, patients on chemotherapy, bone marrow disorders and in those due to undergo major bone surgery.

Eporen 4000 Pfs I.U Inj works by stimulating the bone marrow to produce healthy red blood cells (RBC’s) and thus enhances blood production.

Consult your doctor before taking iron supplements along with Eporen 4000 Pfs I.U Inj as they might increase the effectiveness of Eporen 4000 Pfs I.U Inj when taken together.

Eporen 4000 Pfs I.U Inj might affect other treatments or tests. Therefore, inform the doctor/lab assistant that you are taking Eporen 4000 Pfs I.U Inj.

Not commonly. However, cases of Steven Johnson’s syndrome and Toxic Epidermal Necrosis (TEN), have been reported in rare instances. Consult your doctor immediately if you notice symptoms such as reddish-circular patches, skin peeling, fever, flu, ulcers of throat, mouth, nose, eyes or genitals.

Eporen 4000 Pfs I.U Inj may cause blood clots (deep vein thrombosis and embolism). Consult your doctor if you experience symptoms such as breathlessness, chest pain, painful swelling and redness in the legs.

The common side effects of Eporen 4000 Pfs I.U Inj may include vomiting, diarrhoea, fever, and nasal congestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Eporen 4000 Pfs I.U Inj contains Recombinant Human Erythropoietin Alfa. A hormone medication that stimulates the bone marrow to produce more red blood cells, correcting low blood counts and anaemia.

Don't stop taking your medication just because you're feeling better! This is a crucial moment in your recovery. Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. They will guide you on how to safely taper off the medication, if necessary, monitor for any potential side effects, and ensure the infection is fully cleared.

Eporen 4000 Pfs I.U Inj is usually given to you by a healthcare professional through an Intravenous(veins). In some cases, you may need to go to a local clinic or learn to self-inject, but only after proper training from a doctor or nurse.

You can store Eporen 4000 Pfs I.U Inj in the refrigerator or a cool, dry place away from sunlight. Do not freeze. Use at room temperature only.

Store Eporen 4000 Pfs I.U Inj in a refrigerator or in a cool, dry place away from sunlight. Keep it out of reach of children. Do not freeze it.

Taking more than the prescribed dose doesn't provide extra relief; instead, it may increase the risk of adverse effects, potentially harming your health.

Don't use Eporen 4000 Pfs I.U Inj if the solution is expired, frozen, or allergic to it. It's also not recommended for those with hypersensitivity disorders, thromboembolism, and red cell aplasia. Pregnant or breastfeeding women or children unless the doctor suggests it. Always consult your doctor before using.

Eporen 4000 Pfs I.U Inj can be used in children under a doctor's guidance and in prescribed pediatric doses.

Eporen 4000 Pfs I.U Inj may increase blood pressure or worsen existing high blood pressure, especially in patients with kidney failure, due to the rapid increase in red blood cells. Inform your doctor beforehand if you have any blood pressure issues. Your doctor will adjust the dose if the benefits outweigh the risks.

Country of origin

INDIA

Manufacturer/Marketer address

No.71, Nehru Nagar, 2Nd Link Street, Industrial Estate, Kottivakkam, Chennai Chennai Tn 600096 In
Other Info - EPO0050

Disclaimer

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Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:25 AM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-1023/epoetin-alfa-injection/details
  2. https://www.medicines.org.uk/emc/files/pil.3442.pdf
  3. https://www.sciencedirect.com/topics/medicine-and-dentistry/recombinant-erythropoietin
  4. https://pubmed.ncbi.nlm.nih.gov/12735213/

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