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EPOTRUST 10000IU INJECTION is used to treat anaemia in cancer, chronic kidney disease, and HIV. It contains Epoetin alfa which works by stimulating the bone marrow to make more red blood cells. In some cases, this medicine may cause side effects such as diarrhoea, vomiting, fever, feeling sick, stuffy nose and sore throat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About EPOTRUST 10000IU INJECTION

EPOTRUST 10000IU INJECTION is a prescription injectable medication used to treat anemia, a condition where your body does not have enough healthy red blood cells. It is primarily prescribed for people with chronic kidney disease, cancer patients undergoing chemotherapy, or patients scheduled for major surgery. By boosting your red blood cell levels, EPOTRUST 10000IU INJECTION helps restore your body's ability to carry oxygen efficiently.

You will typically inject EPOTRUST 10000IU INJECTION either once a week, a few times a week, or once every few weeks, depending on your treatment plan. Since it is injected, it can be taken with or without food, as meals do not affect how it works in your body. Making sure you eat iron-rich foods and stay well-hydrated during treatment can significantly improve your results.

While using EPOTRUST 10000IU INJECTION, you may experience mild side effects like headaches, high blood pressure, or soreness at the injection site. However, you must contact your doctor immediately if you experience serious symptoms like sudden chest pain, shortness of breath, or severe dizziness.

Do not take this if you have uncontrolled high blood pressure or if you have ever had a rare blood condition called pure red cell aplasia after using this type of medicine. Talk to your doctor before starting this medication if you have a history of heart disease, seizures, or blood clots.

Certain medicines like cyclosporine can interact with EPOTRUST 10000IU INJECTION, and drinking alcohol or smoking can affect your blood pressure and overall heart health during treatment. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, you must consult your healthcare provider to ensure this treatment is safe for you.

Uses of EPOTRUST 10000IU INJECTION

EPOTRUST 10000IU INJECTION is used in the treatment of anemia in cancer, anemia in chronic kidney disease, and anemia in HIV. The detailed uses of EPOTRUST 10000IU INJECTION are as follows:

  • Anemia due to chronic kidney disease: Helps the body produce more red blood cells when the kidneys cannot make enough natural hormone.
  • Anemia caused by chemotherapy: Restores red blood cell levels in cancer patients undergoing chemotherapy, reducing the need for blood transfusions.
  • Anemia before major surgery: Boosts red blood cells prior to scheduled surgeries to reduce the risk of needing a blood transfusion during or after the procedure.
  • Anemia in HIV-infected patients: Treats low red blood cell counts caused by certain HIV medications.
     

Key Benefits

EPOTRUST 10000IU INJECTION helps treat anaemia by stimulating the production of red blood cells, improving oxygen delivery throughout the body. Increasing red blood cell levels helps reduce symptoms of anaemia and supports better daily functioning.

Benefits may include:

  • Helps increase red blood cell production and improve haemoglobin levels.
  • Reduces tiredness, weakness, and fatigue associated with anaemia.
  • Improves oxygen delivery to the body's tissues and organs.
  • May reduce the need for blood transfusions in appropriate patients.
  • Helps improve physical activity, exercise tolerance, and overall quality of life.
  • Supports long-term management of anaemia under medical supervision.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of EPOTRUST 10000IU INJECTION. Typically, it is administered 3 times a week.
  • EPOTRUST 10000IU INJECTION will be administered subcutaneously (under the skin) or intravenously (through the vein) by the doctor or nurse in a medical setting.
  • Do not self-administer it.

How EPOTRUST 10000IU INJECTION Works

EPOTRUST 10000IU INJECTION is an erythropoietin, a hormone naturally produced by healthy kidneys. It sends signals directly to your bone marrow, which is the soft centre of your bones where blood cells are made. These signals instruct your bone marrow to produce more red blood cells. As these new red blood cells enter your bloodstream, they carry vital oxygen from your lungs to the rest of your body, resolving the symptoms of anaemia.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking EPOTRUST 10000IU INJECTION as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking EPOTRUST 10000IU INJECTION if you are pregnant unless prescribed by a doctor as EPOTRUST 10000IU INJECTION is a pregnancy category B drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks. If prescribed use only single-dose vials (the benzyl alcohol-free formulation) in pregnant women.

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Breast Feeding

Caution

Consult your doctor before taking EPOTRUST 10000IU INJECTION; your doctor will decide whether EPOTRUST 10000IU INJECTION can be taken by breastfeeding mothers or not.

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Driving

Caution

EPOTRUST 10000IU INJECTION causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

EPOTRUST 10000IU INJECTION should not be given to neonates as the safety and efficacy have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using EPOTRUST 10000IU INJECTION. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of EPOTRUST 10000IU INJECTION in elderly patients. Please consult your doctor.

What if I have taken an overdose of EPOTRUST 10000IU INJECTION

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. An overdose can lead to severe high blood pressure or life-threatening blood clotting issues.

Diet & Lifestyle Advise

  • Eat iron-rich foods: Your body needs iron to build red blood cells. Incorporate foods like lean meats, green leafy vegetables, and beans into your meals, as recommended by your doctor.
  • Track your blood pressure daily: Because EPOTRUST 10000IU INJECTION can raise your blood pressure, keep a daily record of your readings to share with your healthcare team.
  • Stay hydrated: Drink plenty of water throughout the day, unless your doctor has advised you to limit your fluid intake due to kidney problems.
  • Stand up slowly: If you feel dizzy or lightheaded, take your time when moving from a sitting or lying position to standing.
     
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How Soon It Starts Working

The time required for EPOTRUST 10000IU INJECTION to start to work: The time required for EPOTRUST 10000IU INJECTION to show its action is unknown. The time for which the effects of EPOTRUST 10000IU INJECTION last: The duration of action for EPOTRUST 10000IU INJECTION is clinically unknown.

What if you forget to take EPOTRUST 10000IU INJECTION

If you miss an injection, do not take a double dose to make up for the missed one. Contact your doctor or pharmacist immediately to get a safe, updated injection schedule.

Storage

• Store EPOTRUST 10000IU INJECTION in the refrigerator between 2°C and 8°C (36°F to 46°F).
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Always inspect the vial before use: Never inject the liquid if it is cloudy, discolored, or has tiny floating specks in it.
  • Never shake the bottle: Shaking ruins the active protein inside the medicine. If you accidentally shake the vial, do not use it.
  • Rotate your injection sites: Avoid injecting into the exact same spot twice in a row to protect your skin from becoming hard, scarred, or irritated.
  • Practice strict needle safety: Always use a fresh, sterile needle and syringe for every injection, and never share them with anyone else.
  • Watch for signs of blood clots: Seek emergency care immediately if you notice sudden swelling, warmth, or deep pain in one leg, or sudden shortness of breath.
     

verifiedApollotooltip
  • Immunosuppressive medicines (e.g., cyclosporine): Taking these medicines alongside EPOTRUST 10000IU INJECTION may affect the levels of both medicines in the body. Your doctor may monitor your blood tests closely and adjust the dose if needed.
  • Iron supplements: Iron supplements are often prescribed with EPOTRUST 10000IU INJECTION to support red blood cell production. Your doctor may monitor your iron levels and blood counts to ensure safe and effective treatment.

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verifiedApollotooltip

No clinically significant food interactions are known with EPOTRUST 10000IU INJECTION when used as directed.     
 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ERYTHROPOIESIS STIMULATING AGENTS (ESAs)]

FAQs

EPOTRUST 10000IU INJECTION is used to treat anaemia (low red blood cell count) in people with chronic kidney disease (CKD), patients affected with HIV, and those receiving chemotherapy for cancer (except for bone marrow or blood cells cancer).
EPOTRUST 10000IU INJECTION contains a protein "Epoetin alfa", which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
A person who is allergic to any chemical compound present in EPOTRUST 10000IU INJECTION or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.
It is suggested to store the EPOTRUST 10000IU INJECTION in the refrigerator between 2 and 8 ℃ and protect it from light. However, a person should not freeze it.
The common side-effects of EPOTRUST 10000IU INJECTION are headache and pain, redness at the injection site. These side-effects are usually mild and temporary. However, inform your doctor immediately if any of these side-effects persist or get worse.
EPOTRUST 10000IU INJECTION will be administered subcutaneously (under the skin) or intravenously (through the vein) by the doctor or nurse based on individual considerations.
Since EPOTRUST 10000IU INJECTION will be administered by the doctor it is unlikely to exceed the recommended dose. However, seek medical attention if you experience symptoms of overdose such as a fast or racing heartbeat.
Yes, EPOTRUST 10000IU INJECTION will be given to children by the doctor if needed. However, it should not be given to children under 1 month of age, as its safety and effectiveness have not been established for this age group. Consult the doctor if you have any concerns.
Yes, EPOTRUST 10000IU INJECTION may cause hypertension (high blood pressure). The doctor will control high blood pressure before and during treatment. However, it is not recommended for people with uncontrolled hypertension. Let the doctor know if you have hypertension before starting treatment with EPOTRUST 10000IU INJECTION.
Yes, you can learn to self-inject EPOTRUST 10000IU INJECTION at home after receiving proper training from your healthcare provider. Do not attempt to inject yourself until you are fully confident in the process. Talk to your doctor or pharmacist if you have any questions.
EPOTRUST 10000IU INJECTION can cause your blood pressure to rise, especially when your red blood cell count increases quickly. Regular checks help ensure your blood pressure stays within a safe range. Talk to your doctor if you notice high readings.
No, you must never freeze EPOTRUST 10000IU INJECTION. Freezing ruins the active ingredients, making the injection useless and unsafe. If a vial freezes, throw it away. Talk to your pharmacist if you need storage advice.
Many patients need iron supplements because the body uses up iron rapidly to make new red blood cells. Your doctor will test your iron levels and prescribe a supplement if necessary. Talk to your doctor before starting any over-the-counter iron pills.
Do not use the medicine if it is cloudy, discolored, or contains any floating particles. The liquid should always be clear and colorless. Talk to your pharmacist to get a replacement vial.
You should only use EPOTRUST 10000IU INJECTION during pregnancy or breastfeeding if the benefits clearly outweigh the potential risks. Talk to your doctor to discuss safer alternatives or special monitoring.
While there is no direct interaction between alcohol and EPOTRUST 10000IU INJECTION, drinking can affect your blood pressure and overall hydration, which are crucial when treating anemia. Talk to your doctor or pharmacist about safe alcohol limits for your specific condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - EPO0046
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