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compositionComposition:ERLOTINIB-150MG
prescription
Prescription Medicine
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Erlosam 150 mg Tablet is used to treat lung and pancreatic cancer. It contains Erlotinib which works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In some cases, this medicine may cause side effects such as abdominal pain, bone pain, constipation, cough, diarrhoea, fatigue, fever, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ERLOTINIB-150MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Erlosam 150 mg Tablet

Erlosam 150 mg Tablet is a prescription medication used to treat specific types of non-small cell lung cancer that has spread to nearby tissues or other parts of the body. It is also used in combination with other therapies to treat advanced pancreatic cancer. This medicine plays an important role in slowing the growth and spread of cancer cells.

This medication is typically taken once daily, and consistency is key to keeping a stable level of the medicine in your body. You must take this tablet on an empty stomach, either at least one hour before or two hours after eating, as food can significantly change how the medicine is absorbed. Adopting healthy habits, such as protecting your skin from the sun and staying well-hydrated, can help support your body during this treatment.

While taking this medicine, you may experience common side effects like skin rashes or diarrhoea, which are usually manageable. However, it is vital to contact your doctor immediately if you experience severe symptoms, such as sudden breathing difficulties, severe stomach pain, or yellowing of your eyes and skin.

Before starting this treatment, talk to your doctor if you have a history of liver disease, kidney problems, lung inflammation, or eye disorders. Do not take this medicine if you are pregnant, planning to become pregnant, or have had a severe allergic reaction to any of its ingredients.

This medicine can interact with several substances; for instance, smoking tobacco speeds up how fast your body removes the drug, making it less effective, while certain acid-reducing medications can stop your body from absorbing it properly. It is highly recommended that pregnant, breastfeeding, or elderly individuals consult their healthcare provider before beginning treatment to ensure it is safe for their specific circumstances.

Uses of Erlosam 150 mg Tablet

Here are the conditions that Erlosam 150 mg Tablet is commonly used to treat:

  • Non-small cell lung cancer: Erlosam 150 mg Tablet is prescribed to treat advanced or metastatic lung cancer that has specific abnormal epidermal growth factor receptor (EGFR) genes, helping to slow down tumor growth and prevent the cancer from spreading further.
  • Pancreatic cancer: In combination with other cancer medicines, Erlosam 150 mg Tablet helps treat advanced pancreatic cancer that has spread to nearby tissues or other organs, helping to control the progression of the disease.

Key Benefits

Erlosam 150 mg Tablet provides several benefits by targeting specific cancer cells and slowing the progression of the disease:

  • Targets Cancer Cells: It specifically blocks EGFR signals that promote the growth and multiplication of certain cancer cells, helping slow tumour growth.
  • Helps Control Disease Progression: By delaying the growth and spread of cancer, it helps manage advanced cancers more effectively.
  • May Help Relieve Cancer-Related Symptoms: Slowing tumour growth may reduce pressure on nearby organs, which can help ease symptoms such as coughing, chest discomfort, or breathing difficulties.
  • Supports Daily Functioning: By helping control the disease, Erlosam 150 mg Tablet may enable some patients to maintain their physical activity and quality of life for longer during treatment.
Side effects of Erlosam 150 mg Tablet

Directions for Use

  • Take Erlosam 150 mg Tablet on an empty stomach, at least 1 hour before or 2 hours after eating a meal or as advised by your doctor.
  • It is advised to take Erlosam 150 mg Tablet once daily; however, follow your doctor's recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How Erlosam 150 mg Tablet Works

Erlosam 150 mg Tablet contains erlotinib, a targeted anticancer medicine that belongs to a class of medicines called tyrosine kinase inhibitors. It works by blocking the epidermal growth factor receptor (EGFR), a protein that plays an important role in the growth and spread of certain cancer cells. In some types of cancer, EGFR is overactive, causing cancer cells to grow and multiply uncontrollably. By blocking the action of EGFR, Erlosam 150 mg Tablet helps stop the growth and division of cancer cells and may slow or stop the spread of the cancer. It can also help shrink tumours in cancers that depend on EGFR signalling for their growth. Together, these actions help control the progression of certain cancers and improve treatment outcomes in patients with EGFR-sensitive tumours.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Erlosam 150 mg Tablet as it may increase the risk of side effects such as dizziness, drowsiness, or difficulty in concentrating.

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Pregnancy

Unsafe

Erlosam 150 mg Tablet is restricted to use in pregnancy. A woman needs to have a negative pregnancy test before starting treatment with this medicine. It is better to use effective birth control methods to prevent pregnancy while taking this medicine or at least 6 months after taking the last dose of Erlosam 150 mg Tablet .

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Breast Feeding

Unsafe

Erlosam 150 mg Tablet should not be taken by breastfeeding mothers as it passes into breast milk and may cause a possible risk to the infant.

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Driving

Caution

It is not known if Erlosam 150 mg Tablet affects your driving ability or not. Drive only if you are physically stable and mentally focussed. If you experience drowsiness after taking this medication, you should not drive or operate any machinery or vehicles.

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Liver

Caution

Erlosam 150 mg Tablet should be taken with caution in patients dealing with liver disease. The doctor may adjust the dose according to the medical condition of the patient.

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Kidney

Caution

Erlosam 150 mg Tablet is safe to take by patients dealing with kidney disease as prescribed by their doctor. The doctor may adjust the dose according to the medical condition of the patient.

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Children

Unsafe

Erlosam 150 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Caution

Erlosam 150 mg Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Erlosam 150 mg Tablet .

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Geriatrics

Caution

The safety and efficacy of Erlosam 150 mg Tablet in older adults are not well established. Please consult your doctor before using Erlosam 150 mg Tablet .

What if I have taken an overdose of Erlosam 150 mg Tablet

If you take too much of this medication, seek immediate emergency medical attention or contact a poison control centre right away. Symptoms of an overdose may include severe diarrhoea or an intense skin rash.

Diet & Lifestyle Advise

  • Avoid smoking: Tobacco smoke significantly lowers the level of Erlosam 150 mg Tablet in your blood, making the treatment much less effective. If you smoke, speak to your doctor about resources to help you quit.
  • Avoid grapefruit products: Grapefruit and grapefruit juice can increase the amount of Erlosam 150 mg Tablet in your system, which raises your risk of experiencing severe side effects.
  • Protect your skin from the sun: This medication makes your skin highly sensitive to sunlight. Wear protective clothing, hats, and apply a broad-spectrum sunscreen with an SPF of 30 or higher daily. Use gentle, alcohol-free moisturisers to manage dry skin.
  • Manage diarrhoea with hydration: If you develop mild diarrhoea, drink plenty of clear fluids such as water, broth, or electrolyte solutions to prevent dehydration. Avoid spicy, greasy, or high-fibre foods that can worsen stomach irritation.
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Have a query?

How Soon It Starts Working

The time required for Erlosam 150 mg Tablet to start to work: The time required for Erlosam 150 mg Tablet to show its action is unknown. The time for which the effects of Erlosam 150 mg Tablet last: The duration of action for Erlosam 150 mg Tablet is clinically unknown.

What if you forget to take Erlosam 150 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is within 12 hours of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are unsure what to do.

Storage

•Store Erlosam 150 mg Tablet tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from direct light and moisture.

Drug Warnings

  • Inspect your tablets: Always examine your tablets before taking them. Do not take any tablet that is broken, chipped, or shows signs of discolouration.
  • Use acid-reducing medicines with caution: Proton pump inhibitors (PPIs) can significantly reduce the absorption of Erlosam 150 mg Tablet and are generally avoided unless your doctor advises otherwise. If you need an antacid or an H2 blocker, your doctor will tell you how to space the doses appropriately to minimise interactions.
  • Use reliable birth control: This medication can cause serious harm to a developing baby. Women of reproductive potential should use highly effective contraception during treatment and for at least 1 month after the final dose. Men with partners who can become pregnant should also discuss appropriate contraception with their doctor during treatment.
  • Do not self-treat severe rashes: If you develop a painful or blistering rash, contact your doctor immediately. Do not apply over-the-counter acne creams, as these can severely irritate your skin further.
  • Monitor your breathing: Because lung inflammation is a rare but serious risk, report any new or worsening cough, shortness of breath, or fever to your healthcare team immediately.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Erlosam 150 mg Tablet and affect its safety or effectiveness: 

  • Proton pump inhibitors (PPIs): PPIs can markedly reduce the absorption of Erlosam 150 mg Tablet and are generally avoided unless your doctor determines they are necessary.
  • H2 blockers and antacids: These medicines can also reduce Erlosam 150 mg Tablet absorption. If they are needed, your doctor will advise you on the correct timing of doses to minimise the interaction.
  • Strong CYP3A4 inhibitors (such as ketoconazole or clarithromycin): These medications can raise the levels of Erlosam 150 mg Tablet in your blood, increasing the risk of serious side effects.
  • Strong CYP3A4 inducers (such as phenytoin, carbamazepine, or rifampin): These medicines can lower the levels of Erlosam 150 mg Tablet in your system, making your cancer treatment less effective.
  • Blood thinners (such as warfarin): Taking these with Erlosam 150 mg Tablet can increase your risk of bleeding or bruising.

Drug-Drug Interactions

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How does the drug interact with Erlosam 150 mg Tablet:
Omeprazole can make Erlosam 150 mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Omeprazole and Erlosam 150 mg Tablet together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Erlosam 150 mg Tablet:
When used in combination with Erlosam 150 mg Tablet, Rabeprazole may prevent the absorption of Erlosam 150 mg Tablet into the circulation, which might make Erlosam 150 mg Tablet less effective in treating cancer.

How to manage the interaction:
Taking Rabeprazole with Erlosam 150 mg Tablet is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
ErlotinibLomitapide
Severe
How does the drug interact with Erlosam 150 mg Tablet:
Taking Erlosam 150 mg Tablet and Lomitapide can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Erlosam 150 mg Tablet and Lomitapide is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ErlotinibMipomersen
Severe
How does the drug interact with Erlosam 150 mg Tablet:
Taking Erlosam 150 mg Tablet and Mipomersen can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Erlosam 150 mg Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Erlosam 150 mg Tablet:
Erlosam 150 mg Tablet's effects and blood levels could both be enhanced by ketoconazole.

How to manage the interaction:
Although taking Ketoconazole and Erlosam 150 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you develop severe or ongoing diarrhea, nausea, vomiting, lack of appetite, skin rash, shortness of breath, cough, or fever, consult a doctor.
How does the drug interact with Erlosam 150 mg Tablet:
Coadministration of Erlosam 150 mg Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlosam 150 mg Tablet with Atorvastatin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Erlosam 150 mg Tablet:
Taking Rifabutin and Erlosam 150 mg Tablet may significantly reduce the blood levels of Erlosam 150 mg Tablet.

How to manage the interaction:
Co-administration of Erlosam 150 mg Tablet with Rifabutin can result in an interaction, but it can be taken if your doctor has advised it. If you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.
ErlotinibEnzalutamide
Severe
How does the drug interact with Erlosam 150 mg Tablet:
Taking Enzalutamide with Erlosam 150 mg Tablet may decrease the blood levels of Erlosam 150 mg Tablet, which may make Erlosam 150 mg Tablet less effective.

How to manage the interaction:
Although taking Enzalutamide and Erlosam 150 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Erlosam 150 mg Tablet:
When Erlosam 150 mg Tablet is taken with primidone, it reduces the blood levels of Erlosam 150 mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Erlosam 150 mg Tablet with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
ErlotinibRifapentine
Severe
How does the drug interact with Erlosam 150 mg Tablet:
When Erlosam 150 mg Tablet is taken with rifapentine, it reduces the blood levels of Erlosam 150 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Erlosam 150 mg Tablet and Rifapentine, you can take these medicines together if advised by a doctor. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and drinks may change how Erlosam 150 mg Tablet is absorbed or processed in your body:

  • Grapefruit and grapefruit juice: These can block the enzymes that break down Erlosam 150 mg Tablet , leading to dangerously high levels of the drug in your body.
  • Food: Eating meals or snacks while taking Erlosam 150 mg Tablet increases its absorption significantly, which can lead to unpredictable drug levels and increased side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Erlosam 150 mg Tablet is used to treat lung and pancreatic cancer.
Erlosam 150 mg Tablet contains Erlotinib, an anti-cancer medication that works by preventing the activity of a protein called epidermal growth factor receptor (EGFR) and hence induces cell death (apoptosis). As a result, the growth and spread of cancer cells in stopped or slowed down.
The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer followed by coughing.
Erlosam 150 mg Tablet is safe to be taken by a diabetic person. However, take Erlosam 150 mg Tablet only after asking with a doctor as they may adjust the dosing according to the patient's condition.
In elderly patients, the risk of side effects is more if you are taking Erlosam 150 mg Tablet . For the patients who are elderly, dose adjustment might be required or your doctor might prescribe any other medication safe for the elderly.
Erlosam 150 mg Tablet can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
No, It is advised to maintain a gap between both the medicines, as use of antacids along with Erlosam 150 mg Tablet may affect the way the Erlosam 150 mg Tablet works. Consult your doctor for further information.
Erlosam 150 mg Tablet should be used with caution in patients using anticoagulants. Erlosam 150 mg Tablet may increase your tendency to bleed. Talk to your doctor, he will need to regularly monitor you with some blood tests.
Erlosam 150 mg Tablet is not recommended for children under 18 years of age, as its safety and efficacy were not established.
No, you should not take Erlosam 150 mg Tablet if you are pregnant or planning to become pregnant as it may cause harm to an unborn baby. Consult the doctor if you have any concerns.
No. Take Erlosam 150 mg Tablet on an empty stomach, at least 1 hour before or 2 hours after food. Taking it with food increases the amount of medicine absorbed into your bloodstream, which may increase the risk of side effects. Follow your doctor's instructions carefully regarding when to take each dose.
Erlosam 150 mg Tablet is a targeted therapy used to treat specific types of non-small cell lung cancer that spread to nearby tissues or any other parts of the body in patients who have previously undergone at least one chemotherapy treatment without improvement.
Yes, Smoking may interfere with Erlosam 150 mg Tablet . It lowers the levels of Erlosam 150 mg Tablet in the blood, potentially reducing its effectiveness in treating the cancer. Avoid smoking while on treatment with Erlosam 150 mg Tablet to treat your condition effectively.
Inform the doctor if you notice a rash while taking Erlosam 150 mg Tablet as it could be a symptom of an allergic reaction.
Erlosam 150 mg Tablet may harm the foetus. Therefore, it is not recommended to become pregnant during treatment with Erlosam 150 mg Tablet . Use effective birth control while taking Erlosam 150 mg Tablet and for at least one month after your final dose. Talk to the doctor if you plan to become pregnant; the doctor will provide guidance on the same.
Erlosam 150 mg Tablet may cause sparse eyelashes (thinning of eyelashes), blepharitis (inflammation of eyelids), and diffuse conjunctival congestion (redness of the eye). Consult the doctor if you notice any eye problems.
Call your doctor if you experience severe diarrhoea, nausea, vomiting, loss of appetite, worsening shortness of breath or cough, new or worsening rash, blistering or peeling of the skin, eye irritation or any changes in smoking habits during treatment with Erlosam 150 mg Tablet .
Moderate alcohol consumption is generally not known to interact directly with Erlosam 150 mg Tablet , but alcohol can irritate your stomach and liver, which are already affected by this medication. It is best to limit or avoid alcohol to protect your organs. Talk to your doctor or pharmacist for personalised advice.
Severe lung inflammation is a rare but life-threatening side effect. If you experience sudden shortness of breath, a new or worsening cough, or a fever, seek immediate medical attention. Talk to your doctor if you have any breathing changes.
Medications that lower stomach acid, like proton pump inhibitors, can prevent Erlosam 150 mg Tablet from being absorbed properly, reducing its effectiveness. If you need antacids, take them at least 2 hours before or 10 hours after your Erlosam 150 mg Tablet dose. Talk to your doctor or pharmacist before taking any new stomach medications.
Erlosam 150 mg Tablet is not a cure, but it is highly effective at slowing down the growth and spread of certain cancer cells, which helps manage the disease and control symptoms. Your doctor will monitor your progress to see how well the medicine is working. Talk to your doctor to understand your specific treatment goals.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - ERL0028
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