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  3. Esava Tablet 10's

Esava Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Esava Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Praise Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esava Tablet

Esava Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Esava Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Esava Tablet as prescribed. Your doctor will advise you on how often you need to take Esava Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Esava Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Esava Tablet . Avoid breastfeeding while taking Esava Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Esava Tablet . Esava Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Esava Tablet

Treatment of Systemic fungal infections

Directions for Use

Take Esava Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Esava Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Esava Tablet Works

Esava Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Esava Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Esava Tablet

Never take more than the prescribed dose. When Esava Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Esava Tablet . Avoid breastfeeding while taking Esava Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Esava Tablet . If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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KetoconazolePimozide
Critical
KetoconazoleLovastatin
Critical

Drug-Drug Interactions

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KetoconazolePimozide
Critical
How does the drug interact with Esava Tablet:
When Pimozide is taken with Esava Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Esava Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleLovastatin
Critical
How does the drug interact with Esava Tablet:
Coadministration of Lovastatin with Esava Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Esava Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleSilodosin
Critical
How does the drug interact with Esava Tablet:
Coadministration of Silodosin with Esava Tablet may lead to side effects including extremely low blood pressure, and increased heart rate.

How to manage the interaction:
Taking Esava Tablet with Silodosin together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation. Do not discontinue any medications without consulting a doctor.
KetoconazoleMethylergometrine
Critical
How does the drug interact with Esava Tablet:
Using Esava Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.

How to manage the interaction:
Taking Esava Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Esava Tablet:
When Methadone is taken with Esava Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Esava Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleNimodipine
Critical
How does the drug interact with Esava Tablet:
When Nimodipine is taken with Esava Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects .

How to manage the interaction:
Taking Esava Tablet with Nimodipine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience -irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without consulting the doctor.
KetoconazoleDofetilide
Critical
How does the drug interact with Esava Tablet:
When Dofetilide is taken with Esava Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Esava Tablet with Dofetilide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleTolvaptan
Critical
How does the drug interact with Esava Tablet:
When Tolvaptan is taken with Esava Tablet, may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan with Esava Tablet is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
KetoconazoleAlfuzosin
Critical
How does the drug interact with Esava Tablet:
Using alfuzosin together with Esava Tablet may significantly increase the blood levels of alfuzosin, which may result in side effects.

How to manage the interaction:
Taking Alfuzosin with Esava Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleNaloxegol
Critical
How does the drug interact with Esava Tablet:
When Naloxegol is taken with Esava Tablet, it can increase the blood levels of naloxegol which may cause the side effects.

How to manage the interaction:
Taking Esava Tablet with Naloxegol is not recommended as it can cause an interaction, but it can be taken if prescribe by the doctor. However, if you experience symptoms such as sweating, tearing, runny nose, chills, diarrhea, stomach pain, anxiety, difficulty sleeping, irritability, restlessness, and yawning, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Esava Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Esava Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Esava Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Esava Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Esava Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Esava Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Esava Tablet .

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Driving

Caution

Esava Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Esava Tablet .

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Liver

Unsafe

Esava Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Esava Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Esava Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

Have a query?

FAQs

Esava Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Esava Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Esava Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Esava Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Esava Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Esava Tablet with other medicines.

No, you are not recommended to stop taking Esava Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Esava Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Esava Tablet , please consult your doctor.

Country of origin

India
Other Info - ESA0030

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jan 1, 2025 | 2:45 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
  2. https://www.drugs.com/mtm/ketoconazole.html
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