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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Esblocip 2.5 gm Dry Powder For Injection 1's is used to treat bacterial infections. It contains Cefepime and Tazobactam which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as pain and swelling at the injection site and skin rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Esblocip 2.5 gm Dry Powder For Injection 1's

Esblocip 2.5 gm Dry Powder For Injection 1's belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Esblocip 2.5 gm Dry Powder For Injection 1's is a combination of two medicines: Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Tazobactam is a beta-lactamase inhibitor. It can improve the spectrum of antibacterial action by inhibiting the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime). Esblocip 2.5 gm Dry Powder For Injection 1's is only used to treat bacterial infections and is not recommended for viral infections.

 Esblocip 2.5 gm Dry Powder For Injection 1's will be administered by a healthcare professional; do not self-administer. The common side effects of Esblocip 2.5 gm Dry Powder For Injection 1's are pain and swelling at the injection site and skin rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Esblocip 2.5 gm Dry Powder For Injection 1's if you are allergic to penicillin, any cephalosporin antibiotic, or its contents. Before taking Esblocip 2.5 gm Dry Powder For Injection 1's, inform your doctor if you have kidney problems, diabetes, gastrointestinal problems, especially colitis (inflammation of the large intestine), or use other antibiotics. Do not discontinue or abruptly stop using Esblocip 2.5 gm Dry Powder For Injection 1's as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). This medicine is not recommended in children aged less than two years. Esblocip 2.5 gm Dry Powder For Injection 1's should be used with caution in pregnant women, breastfeeding mothers and elderly people. Esblocip 2.5 gm Dry Powder For Injection 1's may interact with alcohol. Esblocip 2.5 gm Dry Powder For Injection 1's may not affect your ability to drive.

Uses of Esblocip 2.5 gm Dry Powder For Injection 1's

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Esblocip 2.5 gm Dry Powder For Injection 1's will be administered by the doctor or nurse in a healthcare setting.• Do not self-administer.

Medicinal Benefits

Esblocip 2.5 gm Dry Powder For Injection 1's contains Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic, whereas Tazobactam is a beta-lactamase inhibitor. Esblocip 2.5 gm Dry Powder For Injection 1's has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple moderate to severe bacterial infections such as urinary tract infections (UTI), skin infections, intra-abdominal infections, lower respiratory tract (lung) infections such pneumonia (inflammation of the air sacs present in lungs) and bronchitis (inflammation of the bronchi), septicemia (including infections of the bloodstream), and empiric treatment in febrile neutropenic patients (development of fever in patients with low neutrophil count).

How Esblocip 2.5 gm Dry Powder For Injection 1's Works

Esblocip 2.5 gm Dry Powder For Injection 1's is a combination of two medicines: Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Tazobactam is a beta-lactamase inhibitor. It can improve the spectrum of antibacterial action by inhibiting the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime).

Storage

Keep Esblocip 2.5 gm Dry Powder For Injection 1's out of sight and reach of children.

What if I have taken an overdose of Esblocip 2.5 gm Dry Powder For Injection 1's

Since Esblocip 2.5 gm Dry Powder For Injection 1's is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Esblocip 2.5 gm Dry Powder For Injection 1's should be used with caution in patients with kidney impairment. There is a risk of serious adverse events such as confusion, hallucinations, stupor (a state of near-unconsciousness), and seizures (fits). Esblocip 2.5 gm Dry Powder For Injection 1's may cause Clostridium difficile-associated diarrhoea (CDAD), ranging from mild diarrhea to fatal colitis (inflammation of the large intestine). If CDAD is suspected or confirmed, the doctor may discontinue therapy and advise appropriate fluid and electrolyte management, protein supplementation, and antibiotic therapy to treat CDAD. A Esblocip 2.5 gm Dry Powder For Injection 1's may cause positive direct Coomb’s test, which indicates antibodies against red blood cells. So, it is necessary to let your doctor know that you are taking this medicine before undergoing laboratory tests. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Esblocip 2.5 gm Dry Powder For Injection 1's may cause superinfection (additional infection caused by other microbes) on prolonged use.

Drug-Drug Interactions

verifiedApollotooltip
CefepimeCholera vaccines
Severe
CefepimeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefepimeCholera vaccines
Severe
How does the drug interact with Esblocip 2.5 gm Dry Powder For Injection:
Taking the cholera vaccine after or along with Esblocip 2.5 gm Dry Powder For Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Esblocip 2.5 gm Dry Powder For Injection and Cholera vaccines together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.
CefepimeCholera, live attenuated
Severe
How does the drug interact with Esblocip 2.5 gm Dry Powder For Injection:
Taking the cholera vaccine after or along with Esblocip 2.5 gm Dry Powder For Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Esblocip 2.5 gm Dry Powder For Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. Make sure to inform the doctor if you are on Cholera vaccine dose or you have already taken it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. In case of any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Esblocip 2.5 gm Dry Powder For Injection 1's to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.

  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.

  • Avoid alcoholic beverages can make you dehydrated and also affect your sleep.  This can make it harder for your body to aid the antibiotic in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Esblocip 2.5 gm Dry Powder For Injection 1's Substitute

Substitutes safety advice
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Alcohol

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's may interact with alcohol. Consult your doctor before consuming any alcohol.

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Pregnancy

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if prescribed by a doctor.

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Breast Feeding

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's may pass into breast milk in small amounts. So, caution should be exercised when given to breastfeeding mothers.

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Driving

Safe if prescribed

Esblocip 2.5 gm Dry Powder For Injection 1's may not affect your ability to drive.

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Liver

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's should be used with caution in patients with live diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Esblocip 2.5 gm Dry Powder For Injection 1's is not recommended for children below two years of age. It can be used safely in children above two years. Please consult your doctor for more information.

Have a query?

FAQs

Esblocip 2.5 gm Dry Powder For Injection 1's is used to treat bacterial infections.

Esblocip 2.5 gm Dry Powder For Injection 1's contains Cefepime and Tazobactam. Cefepime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Tazobactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (cefepime).

The common side-effects of Esblocip 2.5 gm Dry Powder For Injection 1's are pain and swelling at the injection site, diarrhea, nausea, vomiting, headache and skin rash. These side-effects are usually mild and temporary. However, inform your doctor immediately if any of these side-effects persist or get worse.

In individuals who have kidney problems, colitis (inflammation of the intestine), and diabetes, Esblocip 2.5 gm Dry Powder For Injection 1's should be used with caution as this medicine may worsen the condition.

Esblocip 2.5 gm Dry Powder For Injection 1's may cause diarrhoea like most of the antibiotics. So, if you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor immediately. Taking plenty of fluids may help in preventing dehydration. Do not take any medicine on your own to treat diarrhoea.

People allergic to penicillin should not take Esblocip 2.5 gm Dry Powder For Injection 1's as they may develop cross-sensitivity (sensitivity to drugs with similar structures). Esblocip 2.5 gm Dry Powder For Injection 1's contains cefepime, which has a similar structure to that of penicillin.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - ESB0021

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