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compositionComposition:ESOMEPRAZOLE-40MG
prescription
Prescription Medicine
info
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Esozrit 40mg Injection belongs to the class of proton pump inhibitors. It is used as a short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It contains esomeprazole, which helps decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, and nausea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ESOMEPRAZOLE-40MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Esozrit 40mg Injection

Esozrit 40mg Injection is a prescription medicine injected into a vein to treat conditions caused by excess stomach acid, such as severe acid reflux and stomach ulcers. It is typically used when you are temporarily unable to take medicines by mouth. This treatment helps heal acid damage in your oesophagus and stomach, providing crucial relief when you need it most.

This medicine is usually given once daily as directed by your healthcare provider, and consistent use is key to helping your stomach lining heal completely. Since it is injected directly, it does not rely on food intake to work, though making positive lifestyle changes can greatly support your recovery. Avoiding trigger foods like citrus and caffeine, eating smaller meals, and not lying down right after eating can significantly improve your overall results.

While receiving this medicine, you might experience mild, common side effects such as headaches, gas, or mild redness at the injection site. However, if you develop severe watery diarrhoea, muscle spasms, or signs of a serious allergic reaction, you must consult your doctor immediately. Your healthcare team is trained to monitor you closely for any unusual reactions during your treatment.

Before starting this medicine, talk to your doctor if you have severe liver damage, low magnesium levels in your blood, or weak bones, as your treatment may require close monitoring. Do not take this medicine if you have had a severe allergic reaction to similar acid-reducing drugs in the past.

Esozrit 40mg Injection can interact with certain blood thinners and HIV medications, reducing their effectiveness or changing how your body processes them. It is also important to avoid smoking and limit alcohol, as both can irritate your stomach lining and delay healing. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor to ensure this treatment is safe for your specific situation.
 

Uses of Esozrit 40mg Injection

Esozrit 40mg Injection is prescribed to reduce excessive stomach acid and is used to treat conditions involving acid-related damage, ulcer healing, prevention of rebleeding, and rare disorders of excessive acid production.

  • Gastroesophageal Reflux Disease (GERD) with esophagitis: Esozrit 40mg Injection helps heal the severe inflammation and erosions in your food pipe caused by stomach acid washing backward.
  • Stomach and Duodenal Ulcers: Esozrit 40mg Injection helps heal painful sores in the lining of your stomach or the upper part of your small intestine.
  • Prevention of Rebleeding after Endoscopy: Esozrit 40mg Injection is injected to significantly lower the risk of ulcers bleeding again after they have been treated during an endoscopy procedure.
  • Zollinger-Ellison Syndrome: Esozrit 40mg Injection helps manage this rare condition where the stomach produces extreme, harmful amounts of acid.
     

Key Benefits

The benefits of Esozrit 40mg Injection include relieving acid-related symptoms, promoting healing of damaged tissues, preventing serious complications, and improving comfort during recovery.

  • Relieves severe acid-related symptoms: Reduces heartburn, acid reflux, and pain caused by excessive stomach acid.
  • Promotes healing of ulcers and oesophagitis: Creates an environment that allows ulcers and inflamed tissues to heal more effectively.
  • Reduces the risk of ulcer rebleeding: Helps prevent recurrent bleeding after successful endoscopic treatment of bleeding ulcers.
  • Improves comfort while eating and swallowing: Reduces irritation in the digestive tract, making swallowing and eating more comfortable during recovery.
     

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Esozrit 40mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Esozrit 40mg Injection Works

Esozrit 40mg Injection contains Esozrit 40mg Injection, a proton pump inhibitor (PPI) that helps reduce the amount of acid produced in the stomach. Esozrit 40mg Injection works by blocking the proton pumps present in the acid-producing cells of the stomach lining. These pumps are responsible for releasing stomach acid that helps digest food. By inhibiting their action, Esozrit 40mg Injection significantly reduces the production of stomach acid. Lowering stomach acid creates a less acidic environment, allowing the lining of the oesophagus, stomach, and upper intestine to heal. It also helps relieve symptoms such as heartburn, acid reflux, and stomach discomfort while preventing further acid-related damage. Together, these actions help reduce stomach acid, promote healing of acid-related damage, and provide long-lasting relief from conditions such as acid reflux, gastric ulcers, and gastro-oesophageal reflux disease (GORD).
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Alcohol

Caution

Drinking alcohol or alcoholic beverages with Esozrit 40mg Injection may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid/limit alcohol.

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Pregnancy

Caution

Consult a doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Esozrit 40mg Injection.

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Breast Feeding

Caution

Consult a doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Esozrit 40mg Injection.

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Driving

Caution

In rare cases, Esozrit 40mg Injection may cause dizziness and impaired vision. Do not drive if you experience these symptoms.

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Liver

Caution

Esozrit 40mg Injection should be taken with precaution in patients with liver disease. Inform your doctor before receiving Esozrit 40mg Injection if you have had a liver impairment/disorder history. The doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Esozrit 40mg Injection should be taken with precaution in patients with kidney disease. Inform your doctor before receiving Esozrit 40mg Injection if you have had a history of severe kidney impairment/disorder. The doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Esozrit 40mg Injection can be given to children aged 1 month or older under the supervision of a healthcare provider.

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Heart

Caution

Esozrit 40mg Injection should be administered with caution in patients with heart problems. Therefore, please inform your doctor before receiving Esozrit 40mg Injection.

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Geriatrics

Caution

Esozrit 40mg Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Esozrit 40mg Injection

Because this medicine is given by healthcare professionals, an overdose is highly unlikely. However, if you suspect you have received too much of this medicine, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Avoid trigger foods: Stay away from highly acidic foods, citrus fruits, tomatoes, chocolate, onions, spicy meals, and fatty dishes that can worsen acid reflux.
  • Limit certain beverages: Reduce your intake of caffeine, carbonated drinks, and alcohol, as these can relax the muscle valve between your oesophagus and stomach, causing acid to leak upward.
  • Eat smaller, frequent meals: Consuming smaller portions helps prevent your stomach from becoming overly full, reducing the pressure that drives acid upward.
  • Stay upright after eating: Avoid lying down or bending over for at least two to three hours after eating to allow gravity to keep acid in your stomach.
  • Manage stress: High stress levels can increase stomach acid production and worsen ulcer symptoms; consider practising relaxation techniques like deep breathing or meditation.
     
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How Soon It Starts Working

The time required for Esozrit 40mg Injection to start to work: Esozrit 40mg Injection ideally starts to show its action immediately after the administration.

The time for which the effects of Esozrit 40mg Injection last: Esozrit 40mg Injection effect lasts for 9 hours.

What if you forget to take Esozrit 40mg Injection

Since this medicine is usually injected by a healthcare provider in a clinical setting, missing a dose is unlikely. However, if you miss a scheduled appointment for your injection, contact your healthcare provider right away to reschedule and get guidance on your treatment plan.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the solution: Always inspect the liquid before it is injected; it should be clear and colourless to pale yellow. Do not use it if you notice any cloudiness, discolouration, or floating particles.
  • Rotate injection sites: If you are receiving multiple injections over several days, ask your provider to rotate the injection site to minimise vein irritation and discomfort.
  • Check for kidney health: Use of acid-reducing medicines can sometimes cause kidney problems, so alert your doctor if you experience changes in your urination, such as blood in the urine or a sudden decrease in volume.
  • Monitor bone health: Daily use of this medicine over a long period (more than a year) may increase the risk of bone fractures; discuss with your doctor if you need calcium or vitamin D supplements.
  • Report severe skin reactions: Seek immediate medical care if you develop a severe, peeling skin rash or blisters, as this can be a rare but life-threatening reaction.
     

verifiedApollotooltip

The following medicines may interact with Esozrit 40mg Injection and may require dose adjustments, additional monitoring, or alternative treatment:

  • Blood thinners (like clopidogrel): Esozrit 40mg Injection may reduce the effectiveness of certain blood thinners, increasing your risk of blood clots.
  • Certain HIV medications (like atazanavir or nelfinavir): This medicine reduces stomach acid, which can prevent your body from properly absorbing these antiviral medications, making them less effective.
  • Antifungal medications (like ketoconazole or itraconazole): Lower stomach acid levels can significantly decrease the absorption and effectiveness of these medicines.
  • Methotrexate: Taking Esozrit 40mg Injection may increase the levels of methotrexate in your blood, raising the risk of severe side effects.

 

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verifiedApollotooltip

No clinically significant food interactions are known with Esozrit 40mg Injection when used as directed.
 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

Esozrit 40mg Injection belongs to the class of drugs known as proton pump inhibitors, used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults.
Esozrit 40mg Injection impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach, thereby helping treat GERD.
No. Gas and acidity are two different conditions. Acidity is caused by improper functioning of the valve (sphincter) located at the junction of the stomach and the food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.
On long-term treatment, Esozrit 40mg Injection may cause low magnesium levels. Low magnesium levels can make you tired, confused, and dizzy and cause muscle cramps, shakiness, and an irregular heartbeat. Inform the doctor if you experience any of these symptoms.
Esozrit 40mg Injection may alter certain medical tests, like secretin stimulation tests and urine screening tests for tetrahydrocannabinol (THC). So, if you are undergoing diagnostic tests, inform your doctor that you are taking Esozrit 40mg Injection.
Esozrit 40mg Injection may slightly increase the risk of hip, wrist, or spine fracture, especially if you take it for longer than a year. Let your doctor know if you have osteoporosis or are taking corticosteroids (which can increase the risk of osteoporosis).
Typically, Esozrit 40mg Injection is injected or infused by a healthcare professional in a clinic or hospital. In rare cases where home administration is prescribed, you or a caregiver will receive detailed training from a nurse. Talk to your doctor if you have questions about where you will receive your doses.
Your doctor may prescribe the injection form of Esozrit 40mg Injection if you are temporarily unable to swallow medicines by mouth, or if you have a severe condition like a bleeding ulcer that requires immediate, direct acid suppression. Talk to your doctor about transitioning to oral tablets once you can swallow comfortably.
You should avoid alcohol while being treated with Esozrit 40mg Injection. Alcohol can directly irritate your stomach lining, worsen acid reflux, and delay the healing of your ulcers or oesophagus. Talk to your doctor or pharmacist for personalised advice.
Long-term use of acid-reducing medicines (usually for more than three years) can make it harder for your body to absorb vitamin B12 from food. If you need this medicine for a long period, your doctor may monitor your vitamin levels. Talk to your doctor if you have concerns.
If you develop watery, severe diarrhoea that does not go away, do not take anti-diarrhoea medicines without consulting your provider. This could be a sign of a serious bacterial infection in your gut. Talk to your doctor immediately.
There is limited research on the use of the injected form of this medicine in pregnant women. Your doctor will weigh the benefits against any potential risks before prescribing it. Talk to your doctor if you are pregnant or planning to become pregnant.
In rare cases, medicines like Esozrit 40mg Injection can cause swelling or inflammation in the kidneys. Alert your doctor if you notice a sudden decrease in how much you urinate, blood in your urine, or unusual swelling. Talk to your doctor if you have pre-existing kidney issues.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - ES46426
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