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compositionComposition:LOSARTAN-50MG+S AMLODIPINE-2.5MG
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Prescription Medicine
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ESPIN LT TABLET is used to treat high blood pressure. It contains Losartan and S-amlodipine which work by preventing the narrowing of blood vessels and increasing blood flow. In some cases, this medicine may cause side effects such as headache, flushing, dizziness, tiredness, palpitations (irregular heartbeat), and upset stomach. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LOSARTAN-50MG+S AMLODIPINE-2.5MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ESPIN LT TABLET

ESPIN LT TABLET is a prescription oral tablet used to treat high blood pressure (hypertension). It helps lower blood pressure, which in turn reduces the risk of serious cardiovascular events like strokes and heart attacks. This combination medication is typically prescribed when a single medicine is not enough to control blood pressure.

This medicine is taken once daily, and it is crucial to take it consistently at the same time every day to maintain stable blood pressure. You can take ESPIN LT TABLET with or without food, as eating does not affect how the medication is absorbed. Adopting a low-sodium diet, exercising regularly, and managing stress can significantly improve the blood-pressure-lowering results of this treatment.

While taking this medication, you may experience mild side effects such as dizziness, ankle swelling, or flushing. However, you must contact your doctor immediately if you experience serious symptoms like a sudden swelling of your face, lips, or throat, or unexplained muscle pain.

Talk to your doctor before starting ESPIN LT TABLET if you have liver damage, kidney issues, or severe dehydration. Do not take this medicine if you are pregnant, as it can cause serious harm or even death to an unborn baby.

This medication can interact with potassium supplements, certain pain relievers, and alcohol, which can lead to dangerously low blood pressure or kidney complications. Pregnant or breastfeeding women should avoid this medication, and elderly individuals may need close monitoring by their doctor to ensure safe use.

Uses of ESPIN LT TABLET

ESPIN LT TABLET is used to treat high blood pressure (hypertension). The detailed uses of ESPIN LT TABLET are as follows:

  • Hypertension (High Blood Pressure): ESPIN LT TABLET is primarily prescribed to treat high blood pressure when a single active ingredient is not sufficient. By lowering blood pressure, it reduces the workload on the heart and blood vessels.
  • Reduction of Cardiovascular Risks: Controlling high blood pressure with ESPIN LT TABLET helps lower the risk of experiencing fatal and non-fatal cardiovascular events, such as strokes and heart attacks.

Key Benefits

ESPIN LT TABLET helps effectively control high blood pressure by combining two complementary blood pressure-lowering medicines in a single tablet. With regular use, it provides consistent blood pressure control, protects vital organs, and supports long-term cardiovascular health.

  • Comprehensive Blood Pressure Control: By combining two different blood pressure-lowering mechanisms, this medicine helps lower your blood pressure more effectively than either medicine alone, bringing it closer to a healthy target range.
  • Protects Against Long-Term Organ Damage: Consistent blood pressure control helps reduce the risk of damage to your blood vessels, kidneys, and eyes, supporting long-term health.
  • Supports a Healthy and Active Lifestyle: By maintaining stable blood pressure, this medicine helps you stay healthier, reduce the risk of cardiovascular complications, and carry out your daily activities with greater confidence.
Side effects of Espin Lt Tablet
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.

Directions for Use

  • Take ESPIN LT TABLET with or without food as advised by your doctor.
  • It is advised to take ESPIN LT TABLET once daily in the morning; however, follow your doctor's recommendation regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How ESPIN LT TABLET Works

ESPIN LT TABLET contains two active medicines that work in complementary ways to relax your blood vessels. By targeting two different pathways in the body, they make it much easier for your heart to pump blood. The first active ingredient, losartan, belongs to a group of medicines called angiotensin receptor blockers (ARBs). It works by blocking a natural substance in the body that causes blood vessels to tighten and narrow. By blocking this substance, it allows the blood vessels to relax and widen. The second active ingredient, amlodipine, is a calcium channel blocker. It works by preventing calcium from entering the muscle cells of your heart and blood vessels. This relaxes the blood vessels, allowing blood to flow more easily. Together, these two ingredients offer a dual approach to managing hypertension.
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Alcohol

Unsafe

It is unsafe to consume alcohol, since alcohol consumption with ESPIN LT TABLET may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Unsafe

ESPIN LT TABLET is not recommended in pregnancy as it can affect and harm the baby. Consult your doctor before taking $ your name if you plan to become pregnant or are already pregnant. Your doctor will weigh the potential risks and benefits before prescribing ESPIN LT TABLET.

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Breast Feeding

Caution

There is no evidence on how ESPIN LT TABLET affects breastfeeding. Please consult your doctor before taking ESPIN LT TABLET if you are breastfeeding.

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Driving

Caution

ESPIN LT TABLET may cause side effects like dizziness, headaches, nausea, or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking ESPIN LT TABLET. The dosage will be initiated in lower doses and will be further increased in patients with liver diseases.

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Kidney

Caution

ESPIN LT TABLET consists of Losartan drug, which may affect the kidney functioning. Hence it is advised to seek doctor advice before starting ESPIN LT TABLET if you have kidney problems.

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Children

Caution

It is not recommended for children below six years. However, for children above six years, give ESPIN LT TABLET in doses as prescribed by a doctor.

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Heart

Caution

Let your doctor know if you have any history of heart problems. Your doctor will weigh the benefits and potential risks before prescribing ESPIN LT TABLET.

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Geriatrics

Caution

ESPIN LT TABLET should be given to elderly patients only when prescribed by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of ESPIN LT TABLET

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose may include severe dizziness, fainting, or an unusually fast or slow heartbeat.

Diet & Lifestyle Advise

  • Limit sodium intake: Reduce your consumption of salt and processed foods, as excess sodium can cause your body to hold onto water and raise your blood pressure.
  • Avoid high-potassium substitutes: Since one of the active ingredients can raise potassium levels in your blood, talk to your doctor before using salt substitutes containing potassium.
  • Stay hydrated, but limit alcohol: Drink plenty of water throughout the day, but limit alcohol intake, as alcohol can interact with this medicine to cause excessive dizziness or a sharp drop in blood pressure.
  • Adopt a heart-healthy diet: Focus on eating whole grains, lean proteins, fruits, vegetables, and low-fat dairy products, which are known to support healthy blood pressure.
  • Engage in regular physical activity: Aim for at least 30 minutes of moderate exercise, such as brisk walking, most days of the week, as approved by your doctor.
health query

Have a query?

How Soon It Starts Working

The time required for ESPIN LT TABLET to start to work: ESPIN LT TABLET ideally shows its action within 4 to 8 hours after administration. The time for which the effects of ESPIN LT TABLET last: The effect of ESPIN LT TABLET lasts for 24 hours.

What if you forget to take ESPIN LT TABLET

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store ESPIN LT TABLET tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep all medications securely out of the reach and sight of children and pets.

Drug Warnings

  • Stand up slowly: To minimise dizziness or the risk of fainting, rise slowly from a sitting or lying position.
  • Monitor your blood pressure: Regularly check and record your blood pressure at home so you can share these readings with your doctor during check-ups.
  • Avoid grapefruit juice: Do not consume grapefruit or grapefruit juice while taking this medication, as it can increase the amount of the medicine in your body and raise the risk of side effects.
  • Check your kidney and liver function: Your doctor may order routine blood tests to check your kidney function and potassium levels while you are taking ESPIN LT TABLET. Keep all of these scheduled laboratory appointments.
  • Alert your surgeon or dentist: If you are scheduled for any surgery or dental procedure, let your surgeon or healthcare provider know that you are taking this blood pressure medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Potassium-sparing diuretics or potassium supplements: May increase the risk of dangerously high potassium levels in the blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Medicines like ibuprofen may decrease the blood-pressure-lowering effect of ESPIN LT TABLET and increase the risk of kidney damage.
  • Other blood pressure medications: Taking this with other antihypertensives can increase the risk of excessively low blood pressure (hypotension).
  • Lithium: ESPIN LT TABLET may increase the levels of lithium in your blood, raising the risk of lithium toxicity.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Can interact with the medication, leading to higher-than-normal levels of the active ingredients in your blood and increasing side effects.
  • Salt substitutes: Those containing potassium can lead to high blood potassium levels when combined with this medication.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

ESPIN LT TABLET is used to treat high blood pressure.
ESPIN LT TABLET lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It dilates (widens) blood vessels and increases blood flow.
ESPIN LT TABLET causes common side effects like ankle swelling, headache, flushing (feeling warmth in the face, ears, neck, and trunk), dizziness, tiredness, palpitations (irregular heartbeat), upset stomach and hyperkalemia (increased potassium levels in the blood), blurred vision, difficulty in breathing.
No, ESPIN LT TABLET can cause high levels of potassium in the blood leading to hyperkalemia. Hence it is not recommended to use potassium supplements along with ESPIN LT TABLET. However, consult your doctor if you are already taking other medicines before starting ESPIN LT TABLET.
Store ESPIN LT TABLET in a cool, dry, and dark place, away from sunlight and moisture. Keep out of the reach of children.
Yes, the use of ESPIN LT TABLET can make you feel dizzy. This may occur when you suddenly rise from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if sitting or lying down. Avoid activities that require high mental alertness, such as driving, until you know how the medication affects you.
ESPIN LT TABLET is not recommended during pregnancy, especially in the first trimester, due to potential fetal risks. Consult your doctor for alternative treatments if you are pregnant or planning to become pregnant.
While taking ESPIN LT TABLET, making lifestyle changes to enhance the medication's effectiveness and overall health is essential. Limit sodium intake to less than 2,300 milligrams per day, and drink plenty of water and other fluids to stay hydrated. Avoid excessive consumption of potassium-rich foods, such as bananas, leafy greens, and sweet potatoes. Engage in regular physical activity, like walking, to help lower blood pressure and maintain a healthy weight through diet and exercise. Additionally, limit alcohol intake to no more than one drink per day for women and two drinks per day for men, quit smoking to reduce cardiovascular risk, and engage in stress-reducing activities, such as meditation or yoga. Consult your doctor or healthcare provider for personalized advice on lifestyle changes while taking ESPIN LT TABLET.
Mild ankle or foot swelling is a known side effect of this medication. However, you should report this to your doctor, as they may want to adjust your dose or suggest ways to manage the swelling. Talk to your doctor before making any changes.
It is best to limit or avoid alcohol while taking this medicine. Alcohol can increase the blood-pressure-lowering effects of ESPIN LT TABLET, making you feel excessively dizzy, lightheaded, or prone to fainting. Talk to your doctor for personalised advice.
While a persistent dry cough is much less common with the ingredients in ESPIN LT TABLET compared to ACE inhibitors, it can still occur in some individuals. If you develop a persistent, dry cough, talk to your doctor to evaluate the cause.
Frequent use of pain relievers like ibuprofen or naproxen (NSAIDs) can reduce the effectiveness of ESPIN LT TABLET and increase the risk of kidney damage. For pain relief, talk to your doctor or pharmacist to find a safer alternative.
The answer includes serious adverse effects such as difficulty breathing and hyperkalemia, which are better presented separately as warnings rather than common side effects.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Rwanda Food and Drugs Authority. Amlozaar Losartan Potassium 50 mg and Amlodipine 5 mg Tablets - Summary of Product Characteristics. Kigali: Rwanda FDA; 2024 Apr [Accessed on 2025 Jun 22]Check here
  5. Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [Accessed on 2025 Jun 22]Check here

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ESP0011
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