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compositionComposition:ESTRADIOL-0.06%W/W
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Estragest 0.06% Gel 80 gm is used to prevent and treat hot flashes in women experiencing menopause. It is also used to treat vaginal itching, dryness, and burning sensations in women undergoing menopause. It contains estradiol, which works by replacing the oestrogen, which is usually produced by the ovaries, thereby providing relief from menopausal symptoms. Common side effects of Estragest 0.06% Gel 80 gm are headache, breast pain or tenderness, diarrhoea, gas and heartburn.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ESTRADIOL-0.06%W/W

Manufacturer/Marketer :

Bioceutics Inc

Consume Type :

Topical

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Estragest 0.06% Gel 80 gm

Estragest 0.06% Gel 80 gm is a prescription topical gel used to treat moderate to severe symptoms of menopause, including sudden hot flashes and night sweats. It works by replacing the natural hormones that your body produces less of during this transitional phase. This helps restore physiological balance and reduces daily discomfort.

To get the best results, you must apply it consistently at the same time every day. Because this is a topical gel absorbed directly through the skin, it does not need to be taken with food or digested. Making healthy lifestyle choices, such as eating a balanced diet and managing stress, can also help support your overall well-being during treatment.

While using this gel, you may experience mild side effects like breast tenderness, headaches, or light skin irritation where the gel was applied. However, you must contact your doctor immediately if you notice serious symptoms like sudden leg swelling, severe chest pain, or unexpected vaginal bleeding.

Talk to your doctor about your complete health history before starting this gel, especially if you have high blood pressure or uterine issues. Do not take this if you have a history of blood clots, heart disease, unexplained vaginal bleeding, breast cancer, or liver damage.

This gel can interact with certain liver-enzyme-affecting drugs, and smoking while using it significantly increases your risk of serious cardiovascular issues like blood clots. You should also consult your doctor if you are elderly, or if you are pregnant or breastfeeding, as this medication is not suitable for these groups.

Uses of Estragest 0.06% Gel 80 gm

Your doctor may recommend this gel to help manage the following conditions:

  • Menopause symptoms: It helps reduce the frequency and severity of moderate to severe hot flashes and night sweats.
  • Vaginal changes: It relieves symptoms of vulvar and vaginal atrophy, such as dryness, irritation, and painful intercourse, caused by lower hormone levels.
  • Hormone replacement: It replaces natural hormones in women who have had their ovaries removed or who experience ovarian failure.

Key Benefits

When applied consistently as directed, this gel may provide the following physiological benefits:

  • Relieves menopause symptoms: It provides reliable relief from the disruptive physical symptoms of menopause, helping you feel more comfortable in your daily life. By reducing the intensity of hot flashes and night sweats, it supports better, more restful sleep.
  • Provides steady hormone delivery: The gel formulation is applied directly to the skin, allowing the active medicine to enter the bloodstream steadily. This route avoids the digestive system, which can provide more consistent hormone levels and reduce the risk of stomach upset associated with oral pills.
  • Improves intimate comfort: It also helps manage localised discomfort, such as vaginal dryness, which can significantly improve comfort and quality of life during physical intimacy.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and use it as advised by the doctor. Apply it as a thin layer to one arm, from the wrist to the shoulder, or on the front of the thigh, or inner arm, as recommended by the doctor.
  • Estragest 0.06% Gel 80 gm is for external use only.
  • Wash your hands before and after use.

How Estragest 0.06% Gel 80 gm Works

Estragest 0.06% Gel 80 gm contains a female hormone that replaces the natural hormones your body stops making during menopause. When you apply the gel to your skin, the medicine is absorbed directly into your bloodstream. Once in the body, it binds to specific hormone receptors, mimicking the actions of natural hormones. This process signals body tissues to regulate temperature and maintain healthy, flexible vaginal tissues, successfully reducing hot flashes and physical dryness.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Estragest 0.06% Gel 80 gm. Consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant or planning pregnancy before using Estragest 0.06% Gel 80 gm.

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Breast Feeding

Consult your doctor

If you are breastfeeding, consult your doctor before using Estragest 0.06% Gel 80 gm.

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Driving

Safe if prescribed

Estragest 0.06% Gel 80 gm does nor affect your ability to drive.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns before using Estragest 0.06% Gel 80 gm.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns before using Estragest 0.06% Gel 80 gm.

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Children

Consult your doctor

Limited information is available. Please consult your doctor.

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Heart

Caution

Estragest 0.06% Gel 80 gm may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Estragest 0.06% Gel 80 gm.

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Geriatrics

Caution

Estragest 0.06% Gel 80 gm should be used with caution in geriatric patients due to increased risk of age-related side effects. Therefore, please consult your doctor before giving Estragest 0.06% Gel 80 gm to elderly individuals.

What if I have taken an overdose of Estragest 0.06% Gel 80 gm

If you apply too much gel or if someone accidentally swallows the product, seek immediate medical attention.

Diet & Lifestyle Advise

  • Support bone health: Decreasing hormone levels can affect bone density. Ensure your diet includes adequate calcium and Vitamin D, or discuss supplements with your doctor.
  • Avoid trigger foods: Limit caffeine, alcohol, and spicy foods, as these are known to trigger or worsen hot flashes.
  • Engage in weight-bearing exercise: Regular walking, jogging, or resistance training helps maintain bone strength and cardiovascular health.
  • Stay cool: Dress in layers and keep your sleeping area cool to help manage night sweats naturally.
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How Soon It Starts Working

The time required for Estragest 0.06% Gel 80 gm to start to work: The time required for Estragest 0.06% Gel 80 gm to show its action is unknown. The time for which the effects of Estragest 0.06% Gel 80 gm last: The duration of action for Estragest 0.06% Gel 80 gm is unknown.

What if you forget to take Estragest 0.06% Gel 80 gm

If you miss a dose, apply it as soon as you remember, provided it is not within 12 hours of your next scheduled dose. If your next dose is less than 12 hours away, skip the missed dose and resume your regular daily schedule. Do not apply a double dose to make up for a missed one.

Storage

• Store it at room temperature, between 20°C and 25°C (68°F and77°F). • Keep the container tightly closed and protect it from direct light, heat, and moisture. Do not freeze the gel.

Drug Warnings

  • Avoid certain areas: Do not apply it to the breasts, vagina, or skin that is cut, scraped, or irritated.
  • Wash your hands: Wash your hands thoroughly with soap and water immediately after applying to avoid accidentally transferring the gel to children or pets.
  • Avoid water exposure: Avoid swimming, bathing, or showering for at least two hours after applying the gel to ensure it is fully absorbed.
  • Avoid other skin products: Never apply sunscreen, moisturisers, or other topical products to the same area of skin immediately before or after applying it.
  • Monitor your skin: Regularly check the skin where you apply the gel for any signs of rash, severe redness, or irritation, and report these to your doctor.

verifiedApollotooltip
  • Medicines affecting liver enzymes: Medicines such as certain antiseizure drugs (e.g., carbamazepine or phenytoin) or antibiotics (e.g., rifampin) may affect how this medicine is processed, which can reduce its effectiveness.
  • Thyroid medicines: This medicine may interact with thyroid medications, and your doctor may need to adjust your thyroid hormone dose.

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verifiedApollotooltip

No clinically significant food interactions are known with Estragest 0.06% Gel 80 gm when used as directed. 

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Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Estragest 0.06% Gel 80 gm is used to treat postmenopausal symptoms such as hot flashes, vaginal itching, dryness, and burning sensation.
Estragest 0.06% Gel 80 gm works by replacing the oestrogen, which is generally produced by the ovaries. Thus, it provides relief from menopausal symptoms.
If you take a bath/shower or use a sauna, apply Estragest 0.06% Gel 80 gm after you have finished bathing/showering or using the sauna and have dried the skin completely.
Avoid unnecessary/prolonged exposure to sunlight as Estragest 0.06% Gel 80 gm may make your skin sensitive to sunlight. Wear protective clothing, sunglasses, and sunscreen. However, do not apply sunscreen before, during, or after applying Estragest 0.06% Gel 80 gm. Maintain a gap of some time between applying Estragest 0.06% Gel 80 gm and sunscreen.
You should apply it to clean, dry, intact skin on your arm or shoulder, as directed by your doctor. Never apply the gel to your breasts or vaginal area. Talk to your doctor or pharmacist if you are unsure where to apply it.
It typically takes about 5 minutes for the gel to dry completely. Wait until the gel is fully dry before putting on clothing over the application site. Talk to your doctor if you experience prolonged stickiness.
You should avoid swimming, bathing, or showering for at least two hours after applying the gel to ensure the medicine has been fully absorbed into your skin. Talk to your doctor or pharmacist if you have questions about your daily schedule.
Wash their skin immediately with soap and water. If they show any unusual signs, such as breast development in young children, contact a doctor or veterinarian right away. Talk to your doctor if exposure occurs.
No, you should not use this gel if you have a history of blood clots, deep vein thrombosis, or pulmonary embolism, as estrogen can increase clotting risks. Talk to your doctor or pharmacist for alternative treatment options.
Smoking while using hormone therapy greatly increases your risk of serious cardiovascular side effects, including blood clots, stroke, and heart attacks. Talk to your doctor about smoking cessation support before starting this medication.
If you still have your uterus, your doctor will likely prescribe a progesterone medication alongside Estragest 0.06% Gel 80 gm to protect your uterine lining. Talk to your doctor or pharmacist to understand your specific treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

No. 15, Plot No. 92B, 6Th Cross Street, Senthil Nagar, Kolathur Chennai 600 099
Other Info - EST0300
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