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compositionComposition:ETOPOSIDE-20MG
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Etopxel 100 Injection 5 ml is used to treat various cancer conditions, including testicular tumours or cancer of the testicles and lung cancer (small cell lung cancer; SCLC). It contains Etoposide, a podophyllotoxin derivative. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ETOPOSIDE-20MG

Manufacturer/Marketer :

Del Trade International Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Etopxel 100 Injection 5 ml

Etopxel 100 Injection 5 ml is an injectable chemotherapy medication prescribed to treat certain types of cancer, most notably small cell lung cancer and testicular cancer. Its primary medical purpose is to slow down or stop the growth of rapidly multiplying cancer cells in the body. By targeting these abnormal cells, it helps control the spread of the disease and can assist in bringing the condition into remission.

Because Etopxel 100 Injection 5 ml is given as an injection into a vein, it is administered in cycles by healthcare professionals in a hospital or specialized clinic. Consistency is vital, and you must attend all your scheduled treatment sessions as planned by your medical team. While receiving this therapy, maintaining a balanced diet, staying well-hydrated, and resting adequately can help your body cope with the treatment and support your overall recovery.

Like many cancer treatments, Etopxel 100 Injection 5 ml can cause side effects, including temporary hair loss, fatigue, nausea, and low blood cell counts. It is important to watch for serious side effects, such as a high fever, severe chills, unusual bruising, or sudden shortness of breath. If you experience any of these severe symptoms, you must contact your doctor or seek emergency medical care immediately.

Before starting this treatment, tell your doctor if you have any pre-existing health conditions, especially liver damage, kidney disease, or a history of low blood cell counts. Before each treatment, your healthcare team will review your medical history, including any previous allergic reactions to Etopxel 100 Injection 5 ml or its ingredients, to help ensure the medicine is safe for you. Be sure to tell your doctor if you have ever experienced a severe allergic reaction to this medicine or any of its components. It is also unsafe for pregnant women, as it can cause serious harm to an unborn baby.

This medicine can interact with other substances, including certain prescription drugs, over-the-counter medicines, and live vaccines, which may increase your risk of severe infections or bleeding. Avoid drinking alcohol during treatment, as it can worsen liver strain and fatigue. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, talk to your doctor or pharmacist about the specific risks and precautions for your age and health group.

Uses of Etopxel 100 Injection 5 ml

This medicine is used to treat certain types of cancer by slowing or stopping the growth of cancer cells. The detailed uses of this medicine are as follows:

  • Small cell lung cancer: It helps slow the rapid growth and division of cancer cells in the lungs, especially when used in combination with other chemotherapy medicines.
  • Testicular cancer: It helps destroy cancer cells in the testicles and is commonly used as part of combination chemotherapy to improve treatment outcomes.
  • Certain blood and lymph cancers: It helps slow or stop the growth of abnormal cells in the bone marrow or lymphatic system in specific types of blood and lymph cancers, as determined by your doctor.

Key Benefits

Etopxel 100 Injection 5 ml helps treat certain cancers by slowing the growth and spread of cancer cells. Its benefits include:

  • Helps slow or stop the growth of rapidly dividing cancer cells, supporting effective cancer treatment.
  • Helps shrink tumors, which may relieve symptoms such as pain, persistent cough, breathing difficulties, or discomfort caused by the cancer.
  • Reduces the spread of cancer cells and supports better disease control when used as part of combination chemotherapy.
  • Improves the chances of achieving remission in certain types of cancer when used according to your treatment plan.
  • Supports overall treatment outcomes and may help improve quality of life by reducing cancer-related symptoms.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Etopxel 100 Injection 5 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Etopxel 100 Injection 5 ml Works

Etopxel 100 Injection 5 ml works by blocking a specific protein (an enzyme) in the body that cancer cells need to repair and copy their genetic material (DNA). When this protein is blocked, the cancer cells suffer severe DNA damage and are unable to divide or multiply. Because cancer cells grow and divide much faster than normal cells, they are highly sensitive to this action, which eventually causes the abnormal cells to die. Since this is an injection given directly into the bloodstream, the medicine travels throughout the body quickly to target cancer cells wherever they are located.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Etopxel 100 Injection 5 ml.

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Pregnancy

Unsafe

Etopxel 100 Injection 5 ml should not be used in pregnant women as it is known to cause fetal damage. Also, a gap of 6 months should be maintained between the last dose of Etopxel 100 Injection 5 ml and your next pregnancy. Hence, inform your doctor if you are planning a pregnancy.

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Breast Feeding

Unsafe

Etopxel 100 Injection 5 ml should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Etopxel 100 Injection 5 ml may impact your ability to drive or operate machinery, so do not drive or do activities that require your mental alertness after taking this medicine.

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Liver

Caution

Inform your doctor before receiving the Etopxel 100 Injection 5 ml if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment or any concerns.

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Children

Caution

Safety and effectiveness in children have not been established.

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Heart

Caution

Etopxel 100 Injection 5 ml can be used in patients with heart problems, but caution is essential. It may cause hypotension or worsen heart conditions, especially in those with pre-existing cardiovascular disease.

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Geriatrics

Caution

Geriatric patients can receive Etopxel 100 Injection 5 ml, but it may be more sensitive to side effects like low blood counts and infections. Dose adjustments and close monitoring are essential to ensure safe and effective treatment.

What if I have taken an overdose of Etopxel 100 Injection 5 ml

An overdose is highly unlikely because this medicine is measured and administered by trained healthcare professionals. However, if you suspect an error has occurred or notice any unusual symptoms after your infusion—including severe breathing difficulty, persistent dizziness, unusual bleeding, or any symptoms that concern you—inform your oncology team immediately or seek emergency medical attention. Prompt reporting helps your healthcare team assess and manage any potential treatment-related complications.

Diet & Lifestyle Advise

  • Avoid infections: Wash your hands frequently with soap and water, avoid crowds, and stay away from people who are sick, as this medicine temporarily lowers your body's ability to fight germs.
  • Stay hydrated: Drink plenty of water and clear fluids daily to help your kidneys process and clear the medication from your system safely.
  • Eat soft, bland foods: To manage nausea and prevent painful mouth sores, choose gentle, non-acidic, and non-spicy foods, and eat smaller, more frequent meals.
  • Maintain good mouth care: Brush gently with a soft toothbrush, keep your mouth clean, and rinse regularly with your doctor's recommended alcohol-free or salt-and-baking soda mouth rinse to help reduce the risk of mouth sores and infection. If painful mouth ulcers develop, inform your healthcare team promptly.
  • Use a soft toothbrush: This helps protect your gums from bleeding, which is especially important when your platelet counts are low.
  • Avoid grapefruit and grapefruit juice: Grapefruit products may affect how Etopxel 100 Injection 5 ml is processed in the body and could alter its effects. Check with your doctor or pharmacist before consuming grapefruit or grapefruit juice during treatment.
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Have a query?

How Soon It Starts Working

The time required for Etopxel 100 Injection 5 ml to start to work: Etopxel 100 Injection 5 ml begins to show its action within a few hours of administration. The time for which the effects of Etopxel 100 Injection 5 ml last: Etopxel 100 Injection 5 ml effect lasts for several days.

What if you forget to take Etopxel 100 Injection 5 ml

Since this medication is given at a clinic by a healthcare provider, missing a dose means missing a scheduled appointment. If you miss an appointment, contact your oncology clinic immediately to reschedule your infusion. Do not double the dose at your next visit to make up for a missed one.

Storage

• Etopxel 100 Injection 5 ml injections are typically stored and managed by the hospital or clinic pharmacy.

Drug Warnings

  • Watch the injection site: Tell your nurse immediately if you feel any burning, stinging, coldness, or pain around the needle during your infusion, as the medicine can damage surrounding tissue if it leaks.
  • Avoid live vaccines: Do not receive any live vaccines (such as the shingles, measles, or mumps vaccine) while using Etopxel 100 Injection 5 ml, as your weakened immune system could lead to a serious infection.
  • Use effective birth control: Both men and women should use highly reliable birth control during treatment and for several months after the last dose to prevent pregnancy, as this medicine can cause severe birth defects.
  • Monitor your blood pressure: Alert your healthcare provider if you feel lightheaded, dizzy, or warm during the injection, as the infusion rate may need to be slowed down.
  • Keep all blood test appointments: You will need regular blood tests before each treatment cycle to monitor your liver, kidneys, and blood cell counts.

verifiedApollotooltip
  • Blood thinners (like warfarin): Combining these can significantly increase your risk of severe bleeding.
    Other chemotherapy medicines: May increase the risk of severe bone marrow suppression, leading to dangerously low blood counts.
  • Immunosuppressant drugs: Can further weaken your immune system, making you highly susceptible to life-threatening infections.
     

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verifiedApollotooltip

No clinically significant food interactions are known with Etopxel 100 Injection 5 ml when used as directed. 
 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHEMOTHERAPY]

FAQs

Etopxel 100 Injection 5 ml is used to treat Testicular cancer, small cell lung cancer, monoblastic leukaemia (AML M5) and acute myelomonoblastic leukaemia (AML M4).
Etopxel 100 Injection 5 ml contains Etoposide, which is used to treat various types of cancers. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.
While taking Etopxel 100 Injection 5 ml, make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and urine tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Etopxel 100 Injection 5 ml.
Do not stop taking Etopxel 100 Injection 5 ml on your own. Take Etopxel 100 Injection 5 ml for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty while taking Etopxel 100 Injection 5 ml.
Etopxel 100 Injection 5 ml can make you more likely to get infections or may worsen any current infections. Avoid contact with people with infections that may spread to others (such as chickenpox, measles, or flu). Consult your doctor if you have been exposed to an infection or for more details.
The live vaccine may not work while on treatment with Etopxel 100 Injection 5 ml. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
The side effects of Etopxel 100 Injection 5 ml include nausea, vomiting, abdominal pain, loss of appetite, temporary hair loss, blood disorders, changes in skin colour, constipation, weakness, dizziness, diarrhoea, and injection site reactions. Consult the doctor if any of these side effects persist or worsen.
It is given as a slow intravenous infusion into a vein by a trained healthcare professional in a hospital or clinic setting. Talk to your doctor.
Yes, temporary hair loss is a very common side effect of this medicine, but your hair will typically begin to grow back after your treatment cycles are completed. Talk to your doctor.
Inform your nurse or doctor immediately, as this could mean the medicine is leaking out of the vein into the surrounding tissue. Talk to your doctor.
Some patients experience extreme tiredness, dizziness, or lightheadedness after an infusion, so it is best to arrange for someone else to drive you home. Talk to your doctor.
It temporarily lowers your body's production of white blood cells, red blood cells, and platelets, which can increase your risk of infection, anemia, and easy bleeding. Talk to your doctor.
No, this medicine is highly toxic to a developing fetus and should not be used during pregnancy. Talk to your doctor.
Blood tests are necessary before each cycle to make sure your liver, kidneys, and blood counts are healthy enough to receive the next dose safely. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

BEETAL HOUSE, 99, MADANGIR BEHIND LOCAL SHOPPING CENTRE DELHI DL 110062 IN.
Other Info - ETO0741
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