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compositionComposition:RIVAROXABAN-2.5MG
prescriptionPrescription Medicine
Exafib 2.5mg Tablet 14's
Exafib 2.5mg Tablet 14's
Exafib 2.5mg Tablet 14's

Exafib 2.5mg Tablet is used to prevent and treat blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism). It contains Rivaroxaban, a blood thinner that works by blocking certain clotting factors in the blood, which helps to prevent clots from forming. By doing this, it reduces the risk of serious conditions, such as stroke or blocked blood vessels. You may experience some common side effects may including bleeding, low red blood cell count (anemia), and nausea. Before taking Exafib 2.5mg Tablet , let your doctor know if you are allergic to any of its ingredients, if you are pregnant or breastfeeding, and about any other medicines you are taking or any health problems you have.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

RIVAROXABAN-2.5MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Exafib 2.5mg Tablet

Exafib 2.5mg Tablet is mainly used to prevent and treat blood clots in the legs (called deep vein thrombosis or DVT) and in the lungs (called pulmonary embolism or PE). Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Exafib 2.5mg Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.

In some cases, Exafib 2.5mg Tablet may cause some common side effects such as bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of Exafib 2.5mg Tablet do not require medical attention and gradually resolve over time. However, talk to your doctor if you experience these side effects continuously.

Tell your doctor if you are allergic to Exafib 2.5mg Tablet or any other medicines. Consult your doctor before using Exafib 2.5mg Tablet if you are pregnant, planning to become pregnant, or breastfeeding. Inform your doctor if you have a stomach ulcer, kidney or liver problems, high blood pressure, or any bleeding disorders before starting Exafib 2.5mg Tablet .

Uses of Exafib 2.5mg Tablet

Exafib 2.5mg Tablet is used to prevent and treat blood clots. The detailed uses of Exafib 2.5mg Tablet are as follows:

  • Treatment of deep vein thrombosis (DVT): Exafib 2.5mg Tablet is used to manage blood clots in the deep veins.
  • Treatment of pulmonary embolism (PE): Exafib 2.5mg Tablet treats clots in the lungs that may cause chest pain and breathing difficulties.
  • Stroke prevention in atrial fibrillation: Exafib 2.5mg Tablet reduces the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
  • Prevention of DVT and PE recurrence: Exafib 2.5mg Tablet reduces the chance of blood clot reformation following initial treatment.
  • Post-surgical DVT prevention: Exafib 2.5mg Tablet is used after knee or hip replacement surgery to prevent clot formation.
  • Treatment of venous thromboembolism (VTE): Exafib 2.5mg Tablet is effective in treating blood clots in veins that can spread to the lungs.
  • Risk reduction in coronary artery disease (CAD): Exafib 2.5mg Tablet lowers the chance of heart attacks and related complications.
  • Risk reduction in peripheral artery disease (PAD):Exafib 2.5mg Tablet reduces clotting risks in the limbs, particularly after procedures like revascularization.

Key Benefits

  • Exafib 2.5mg Tablet belongs to a class of drugs known as anticoagulants or blood thinners. Exafib 2.5mg Tablet is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.
  • Exafib 2.5mg Tablet works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots.
  • Exafib 2.5mg Tablet helps to reduce the chance of serious complications, such as heart attack, stroke, or lung damage caused by blood clots.
Side effects of Exafib 2.5mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Regularly exercise and have a balanced diet to maintain a healthy weight.
  • Eat lot of fruits and vegetables (minimum 5 servings/day).
  • Include vitamin K-rich foods for stable anticoagulation control.
  • Limit red and processed meats.
  • Avoid smoking and consumption of alcohol.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.

Directions for Use

  • Exafib 2.5mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Exafib 2.5mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Exafib 2.5mg Tablet Works

Exafib 2.5mg Tablet contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Exafib 2.5mg Tablet as it may increase the risk of bleeding.

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Pregnancy

Consult your doctor

Tell your doctor before using Exafib 2.5mg Tablet because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Consult your doctor

Exafib 2.5mg Tablet may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

Exafib 2.5mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Exafib 2.5mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Exafib 2.5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Exafib 2.5mg Tablet is not approved for children. Therefore Exafib 2.5mg Tablet is not safe for children.

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Heart

Safe if prescribed

Exafib 2.5mg Tablet is safe for use in heart patients if adminitered by the physician

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Geriatrics

Safe if prescribed

Exafib 2.5mg Tablet can be safely used in elderly patients if prescribed by the physician. Close monitoring of the patient is needed.

What if I have taken an overdose of Exafib 2.5mg Tablet

Do not take more than the prescribed dose of Exafib 2.5mg Tablet as it may cause serious adverse effects such as bloody/black/tarry stools, unusual bleeding or bruising, blood in urine, and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Exafib 2.5mg Tablet and lead to unwanted side effects. Hence, try to avoid these juices while taking Exafib 2.5mg Tablet .
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Have a query?

How Soon It Starts Working

  • The time required for Exafib 2.5mg Tablet to start to work: The time required for Exafib 2.5mg Tablet to start to work is 2 to 4 hours after administration. 
  • The time for which the effects of Exafib 2.5mg Tablet last: The effect of Exafib 2.5mg Tablet lasts for 12 to 24 hours.

What if you forget to take Exafib 2.5mg Tablet

If you miss a dose of Exafib 2.5mg Tablet , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Exafib 2.5mg Tablet should be used with caution in children. Prolonged use of Exafib 2.5mg Tablet may cause hair loss. Regular blood tests are recommended while taking Exafib 2.5mg Tablet to check the time taken for your blood to clot and the level of platelets (blood cells).
  • If you are known to be allergic to Exafib 2.5mg Tablet or any other medicines, please tell your doctor. Consult your doctor before using Exafib 2.5mg Tablet if you are pregnant, planning to become pregnant, or breastfeeding.
  • If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Exafib 2.5mg Tablet .
  • Avoid alcohol and painkillers like ibuprofen unless your doctor says it's safe, as they can increase the risk of bleeding.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Exafib 2.5mg Tablet may interact with antiplatelet drugs (warfarin, enoxaparin), antiviral or HIV medicines (lopinavir, ritonavir), painkillers (aspirin, ibuprofen), antiepileptic drugs (carbamazepine, phenytoin), drugs to treat fungal or bacterial infections (fluconazole, erythromycin, clarithromycin), and herbal medication for depression (St. John's wort).

Drug-Food Interactions: Exafib 2.5mg Tablet may interact with grapefruit juice, cranberry juice, and green tea. 

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems; heart problems; and unstable blood pressure.

RivaroxabanEtodolac
Severe
RivaroxabanIbuprofen
Severe

Drug-Drug Interactions

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RivaroxabanEtodolac
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of Etodolac and Exafib 2.5mg Tablet can increase the risk of bleeding problems, including severe hemorrhage.

How to manage the interaction:
Co-administration of Etodolac and Exafib 2.5mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanIbuprofen
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of Exafib 2.5mg Tablet and Ibuprofen can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Exafib 2.5mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanDalteparin
Severe
How does the drug interact with Exafib 2.5mg Tablet:
The combined use of Dalteparin and Exafib 2.5mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Dalteparin and Exafib 2.5mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanClopidogrel
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Coadministration of Clopidogrel with Exafib 2.5mg Tablet increases the risk of severe bleeding due to the additive effect.

How to manage the interaction:
Although taking clopidogrel with Exafib 2.5mg Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
RivaroxabanFlurbiprofen
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of flurbiprofen and Exafib 2.5mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of flurbiprofen and Exafib 2.5mg Tablet can lead to an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness; lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RivaroxabanPrasugrel
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of Prasugrel and Exafib 2.5mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of prasugrel and Exafib 2.5mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanHeparin
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of heparin and Exafib 2.5mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of heparin and Exafib 2.5mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanStreptokinase
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Co-administration of streptokinase and Exafib 2.5mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of streptokinase and Exafib 2.5mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanCarbamazepine
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Coadministration of carbamazepine and Exafib 2.5mg Tablet may reduce the blood levels of Exafib 2.5mg Tablet, which may reduce the treatment outcomes.

How to manage the interaction:
Although taking carbamazepine and Exafib 2.5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RivaroxabanNaproxen
Severe
How does the drug interact with Exafib 2.5mg Tablet:
Coadministration of Naproxen and Exafib 2.5mg Tablet may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Naproxen and Exafib 2.5mg Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Exafib 2.5mg Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.

No, you are not recommended to stop taking Exafib 2.5mg Tablet without consulting your doctor to worsen the condition. Therefore, take Exafib 2.5mg Tablet for as long as your doctor has prescribed it.

No, Exafib 2.5mg Tablet is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this Exafib 2.5mg Tablet , immediately consult your doctor and inform him about it.

Exafib 2.5mg Tablet has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes Exafib 2.5mg Tablet may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking Exafib 2.5mg Tablet along with other blood thinner medicines.

Avoid taking grapefruit and grapefruit juice while taking Exafib 2.5mg Tablet , and it contains compounds that slow down the metabolism of Exafib 2.5mg Tablet and increase the activity leading to bleeding.

It is not known that Exafib 2.5mg Tablet causes hair loss. Kindly contact your doctor.

Exafib 2.5mg Tablet is a type of medicine known as an anticoagulant. Exafib 2.5mg Tablet works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.

You should take Exafib 2.5mg Tablet just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.

The side effects of Exafib 2.5mg Tablet include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.

Yes, Exafib 2.5mg Tablet is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.

Avoid taking grapefruit and grapefruit juice while taking Exafib 2.5mg Tablet as grapefruit contains compounds that slow down the Exafib 2.5mg Tablet metabolism and increase the activity leading to bleeding. However, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the vitamin K activity or increases the blood clotting such as brussels, spinach, sprouts, broccoli, mustard greens, asparagus and green tea. But, the use of these food items is not restricted with Exafib 2.5mg Tablet .

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

  • Bayyarapu Mahesh Kumar

    M Pharmacy

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - EXA0054
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