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compositionComposition:RIVASTIGMINE-4.5MG
prescription
Prescription Medicine
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Exelon 4.5mg Capsule used to treat mild to moderate dementia (memory loss) associated with Alzheimer's and Parkinson's disease. It increases the levels of a brain chemical called acetylcholine, which helps nerve cells to communicate more easily. It slows cognitive decline and improves cognitive functions, including memory, cognition, and awareness. It also helps patients perform daily activities more easily and improve their overall quality of life.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

RIVASTIGMINE-4.5MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Exelon 4.5mg Capsule

Exelon 4.5mg Capsule is a prescription medicine used to manage symptoms of mild to moderate dementia associated with Alzheimer’s disease and mild to moderate dementia associated with Parkinson’s disease. It belongs to a group of medicines called cholinesterase inhibitors (medicines that help preserve a key brain chemical), which help improve communication between nerve cells in the brain and may support memory, thinking, and daily functioning.

Exelon 4.5mg Capsule is available as oral capsules, oral solution, and a transdermal patch applied to the skin. This article focuses on the oral forms (capsules and oral liquid). Your doctor may choose the patch formulation in some cases, particularly if swallowing difficulties or troublesome stomach-related side effects occur. Do not switch between the oral forms and the patch on your own, as the dose conversion differs between formulations. Always consult your doctor before changing from one formulation to another.

To get the best results, you must take this medicine consistently every day, typically twice a day. It is highly recommended to take Exelon 4.5mg Capsule with your morning and evening meals, as this helps prevent stomach upset. Incorporating a steady daily routine and a balanced diet can further assist in managing cognitive health.

While taking Exelon 4.5mg Capsule , you might experience mild side effects like nausea, vomiting, or a temporary loss of appetite. However, if you develop severe vomiting, extreme dizziness, or faint, you should contact your doctor immediately.

Talk to your doctor before starting this medicine if you have a history of stomach ulcers, irregular heartbeats, asthma, difficulty passing urine, liver disease, or kidney disease. Patients with liver impairment may require slower dose increases, while those with kidney impairment may be more likely to experience side effects and require closer monitoring. Do not take this medicine if you have had a severe allergic reaction to Exelon 4.5mg Capsule , other similar medicines in the same drug family, or similar dementia medicines in the past.

Certain medications, such as some heart medicines and stomach remedies, can interact with Exelon 4.5mg Capsule and alter its effects. It is also important to talk to your doctor or pharmacist if you are pregnant, breastfeeding, or managing other age-related health conditions.

Uses of Exelon 4.5mg Capsule

Your doctor may prescribe this medicine to treat several conditions, including:

  • Alzheimer's disease dementia: Exelon 4.5mg Capsule is used to treat mild to moderate confusion and memory loss by helping support thinking, memory, and everyday function.
  • Parkinson's disease dementia: It helps improve mental function, attention, and daily tasks in people experiencing memory changes due to Parkinson's disease.

Key Benefits

Exelon 4.5mg Capsule provides supportive care for cognitive function by helping improve memory, thinking abilities, and daily functioning. Key benefits include:

  • Supports Memory and Thinking Skills: By improving cognitive function, Exelon 4.5mg Capsule helps patients maintain better mental clarity and manage everyday tasks more independently.
  • Improves Daily Activities: By supporting abilities needed for routine activities such as bathing, dressing, and eating, Exelon 4.5mg Capsule helps promote greater independence and confidence in daily life.
  • Enhances Communication and Social Engagement: By helping maintain cognitive abilities, Exelon 4.5mg Capsule supports better interaction with others and may improve overall quality of life for patients and their caregivers.
  • Exelon 4.5mg Capsule helps manage the symptoms of dementia but does not cure Alzheimer's disease or Parkinson's disease dementia or slow the progression of these conditions. Although many people experience improvement or stabilisation of symptoms during treatment, the benefit may gradually lessen over time as the underlying disease progresses.
Side effects of Exelon 4.5mg Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Take Exelon 4.5mg Capsule with food to avoid any stomach upset.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Exelon 4.5mg Capsule Works

In people with dementia, there are lower levels of a natural chemical messenger in the brain called acetylcholine (think of it as a messenger that carries instructions between brain cells). This chemical is essential for memory, learning, and general cognitive function. Exelon 4.5mg Capsule contains rivastigmine and it works by blocking the action of an enzyme that breaks down this messenger. By preventing the breakdown of acetylcholine, Exelon 4.5mg Capsule increases the amount of this chemical available in the brain. This helps nerve cells communicate more effectively with one another, which can help reduce the symptoms of dementia.
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Alcohol

Caution

It is advised to limit alcohol consumption while taking Exelon 4.5mg Capsule . Alcohol intake, along with Exelon 4.5mg Capsule , may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Exelon 4.5mg Capsule should be used during pregnancy only if the benefit outweighs the risk. Please consult your doctor before taking Exelon 4.5mg Capsule if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Exelon 4.5mg Capsule is excreted into the breast milk. Please consult your doctor before taking Exelon 4.5mg Capsule if you are a breastfeeding mother.

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Driving

Caution

Exelon 4.5mg Capsule may cause dizziness or drowsiness. Do not drive if you experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Please consult your doctor before using Exelon 4.5mg Capsule if you suffer from any liver impairment.

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Kidney

Caution

Please consult your doctor before using Exelon 4.5mg Capsule if you suffer from any kidney impairment.

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Children

Unsafe

Exelon 4.5mg Capsule is not recommended for people under 18.

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Heart

Caution

Exelon 4.5mg Capsule should be used with caution in patients with cardiovascular disease. Please inform your doctor about any existing heart problems before using Exelon 4.5mg Capsule .

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Geriatrics

Safe if prescribed

Exelon 4.5mg Capsule is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Exelon 4.5mg Capsule

If you or someone else takes too much of this medicine, seek emergency medical attention or call a poison control centre immediately. Symptoms of an overdose may include severe nausea, vomiting, salivation, sweating, slow breathing, or fainting.

Diet & Lifestyle Advise

  • Eat small, frequent meals: If you experience nausea or a loss of appetite, eating smaller portions throughout the day rather than three large meals can help.
  • Stay hydrated: Drink plenty of water and other fluids throughout the day, especially if you experience mild diarrhoea or vomiting, to prevent dehydration.
  • Establish a daily routine: Keeping a consistent schedule for meals, waking up, and sleeping can reduce confusion and support cognitive health.
  • Monitor weight: Weigh yourself or the patient regularly, as Exelon 4.5mg Capsule can cause weight loss. Share any significant weight drops with your doctor.
health query

Have a query?

How Soon It Starts Working

  • The time required for Exelon 4.5mg Capsule to start to work: The time required for Exelon 4.5mg Capsule to show its action is not clinically established.
  • The time for which the effects of Exelon 4.5mg Capsule last: The effect of Exelon 4.5mg Capsule lasts for 10 to 12 hours.

What if you forget to take Exelon 4.5mg Capsule

If you miss a dose, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your normal schedule. Do not take a double dose to make up for a missed one. If you have missed taking Exelon 4.5mg Capsule for more than three days, do not take another dose until you have talked to your doctor, as you may need to restart at a lower dose.

Storage

• Store Exelon 4.5mg Capsule at room temperature between 15°C and 30°C (59°F and 86°F). • Keep the medicine in its original container, tightly closed, and store it in a dry place away from direct light and moisture.

Drug Warnings

  • Take exactly as prescribed: Take Exelon 4.5mg Capsule at the same times each day as directed by your doctor. Do not change your dose or stop treatment suddenly without medical advice.
  • Monitor side effects: Inform your doctor if you develop persistent nausea, vomiting, loss of appetite, weight loss, dizziness, fainting, or worsening confusion.
  • Support medication adherence: Caregivers should help ensure the correct dose is taken at the scheduled time, especially if the person has memory difficulties.
  • Managing stomach-related side effects: Nausea, vomiting, loss of appetite, and weight loss can occur, especially when starting treatment or after a dose increase. If severe vomiting, persistent nausea, dehydration, or significant weight loss occurs, contact your doctor. Your doctor may temporarily reduce the dose or adjust treatment rather than stopping the medicine suddenly on your own. 

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Exelon 4.5mg Capsule :

  • Anticholinergic medicines: Certain allergy medicines, bladder control medicines, and other anticholinergic drugs (medicines that block certain nerve signals in the body) may reduce the effectiveness of Exelon 4.5mg Capsule .
  • Beta-blockers: Taking Exelon 4.5mg Capsule with beta-blockers may increase the risk of an unusually slow heart rate and related symptoms.
  • NSAIDs (such as ibuprofen or naproxen): Using these medicines together may increase the risk of stomach irritation or ulcers.
RivastigminePropranolol
Severe
RivastigmineBupropion
Severe

Drug-Drug Interactions

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RivastigminePropranolol
Severe
How does the drug interact with Exelon 4.5mg Capsule:
Coadministration of Exelon 4.5mg Capsule with propranolol can cause an abnormally slow heart rate and low blood pressure.

How to manage the interaction:
Although taking Propranolol together with Exelon 4.5mg Capsule can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.
RivastigmineBupropion
Severe
How does the drug interact with Exelon 4.5mg Capsule:
Talking bupropion and Exelon 4.5mg Capsule together can increase risk of having seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Exelon 4.5mg Capsule can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like muscle spasms or movements, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor. Do not discontinue any medications without consulting a doctor.
RivastigmineMetrizamide
Severe
How does the drug interact with Exelon 4.5mg Capsule:
Taking Exelon 4.5mg Capsule and Metrizamide together may increase the risk of developing seizures (fits).

How to manage the interaction:
Although taking Exelon 4.5mg Capsule and Metrizamide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms like muscle spasms, lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RivastigmineTramadol
Severe
How does the drug interact with Exelon 4.5mg Capsule:
Taking Tramadol with Exelon 4.5mg Capsule can significantly increase the risk of seizures (fits).

How to manage the interaction:
Taking Exelon 4.5mg Capsule with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking of hands and legs, jitteriness, restlessness, pacing, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food: Take Exelon 4.5mg Capsule with food if advised, as this may help reduce stomach irritation.
  • Alcohol: Avoid alcohol while taking Exelon 4.5mg Capsule , as it may increase side effects such as dizziness, drowsiness, or confusion.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- ALZHEIMER'S AGENTS]

FAQs

Exelon 4.5mg Capsule used to treat mild to moderate dementia (memory loss) associated with Alzheimer's disease (a brain disorder that slowly destroys memory and thinking) and Parkinson's disease (a movement disorder that causes tremors and stiffness).
Exelon 4.5mg Capsule contains Rivastigmine, which increases the levels of a brain chemical called acetylcholine by blocking the enzyme responsible for its breakdown. This helps nerve cells to communicate more easily, supporting clearer thinking and better memory.
Exelon 4.5mg Capsule should be used with caution in the medical history of liver or kidney diseases, breathing problems (asthma and COPD), stomach/intestinal problems (ulcers and bleeding), heart diseases (sick sinus syndrome and other conduction disorders), fainting, fits, urination problems and enlarged prostate. Please let your doctor know if you have any other medical problems before starting Exelon 4.5mg Capsule .
Take the medicine as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.
Exelon 4.5mg Capsule may cause side effects such as nausea, vomiting, dizziness, drowsiness, stomach upset, weakness, loss of appetite, tremor or slow heartbeat. If these side effects persist or worsen, please consult your doctor.
Exelon 4.5mg Capsule may take up to 12 weeks to start working. Each person reacts differently to the medicine. The clinical benefits of Exelon 4.5mg Capsule should be evaluated regularly. If the symptoms do not improve after 12 weeks of treatment, Exelon 4.5mg Capsule should be stopped.
Exelon 4.5mg Capsule should be taken as advised by the doctor. Usually, Exelon 4.5mg Capsule is prescribed for twice-daily administration, in the morning and evening, with food. Swallow it as a whole with a glass of water. Do not open, crush or chew it.
Yes, antacids can be taken with Exelon 4.5mg Capsule as they do not interfere with the working of Exelon 4.5mg Capsule . Additionally, some patients may experience increased acid secretion in the stomach. Therefore, your doctor may prescribe an antacid to relieve this acidity.
If you take more than the recommended doses of Exelon 4.5mg Capsule , it may cause stomach pain, diarrhoea, dizziness, headache, tremor, hallucinations, sleepiness, and malaise. Higher doses may also cause increased sweating, confusion, and elevated blood pressure. In case you take an overdose of Exelon 4.5mg Capsule , seek medical attention immediately.
Yes, Exelon 4.5mg Capsule can cause drowsiness or sleepiness, especially at the beginning of treatment or when increasing the dose. If you feel dizzy or sleepy, avoid driving or using machines or performing any tasks that require your attention.
No, do not discontinue Exelon 4.5mg Capsule without consulting your physician. However, if treatment is stopped for more than three days, do not take Exelon 4.5mg Capsule and consult your doctor. The physician will restart the treatment at a low dose twice daily. Subsequently, the dose can be increased gradually, as previously done.
Yes, Exelon 4.5mg Capsule can cause hallucinations. However, hallucinations are reported in very few people. It typically occurs shortly after a dose increase.
No, you should always take Exelon 4.5mg Capsule with food, such as your morning and evening meals. Taking it with food helps to reduce common stomach-related side effects like nausea and vomiting. Talk to your doctor or pharmacist if you struggle with nausea.
If you miss taking your medicine for more than three days, do not take your next scheduled dose. Contact your doctor immediately before restarting, as you may need to restart at a lower dose to avoid severe side effects. Talk to your doctor for specific guidance.
No, Exelon 4.5mg Capsule does not cure Alzheimer's disease or Parkinson's dementia, and it does not stop the underlying disease from progressing. Instead, it helps manage the cognitive symptoms, such as memory loss and confusion, to improve daily functioning. Talk to your doctor about what to expect.
Yes, Exelon 4.5mg Capsule can cause a decrease in appetite and weight loss in some individuals. It is recommended to monitor your weight regularly and report any significant changes to your healthcare provider. Talk to your doctor if you notice a decrease in appetite.
It is highly advised to avoid or limit alcohol while taking this medicine. Alcohol can increase the risk of side effects like dizziness, drowsiness, and confusion, which can worsen dementia symptoms. Talk to your doctor about your alcohol intake.
Yes, dizziness is a known side effect of this medicine. Be cautious when standing up from a sitting or lying position, and avoid activities that require alertness, like driving, until you know how the medicine affects you. Talk to your doctor if dizziness persists.
Yes, you must inform your surgeon, anesthesiologist, or dentist that you are taking Exelon 4.5mg Capsule before any medical or surgical procedure. This medicine can affect how certain anaesthetics and muscle relaxants work in your body. Talk to your doctor before any scheduled surgery.
Contact your doctor if nausea, vomiting, loss of appetite, or weight loss becomes severe or persistent. Your doctor may reduce the dose temporarily or adjust your treatment plan. Do not stop taking Exelon 4.5mg Capsule suddenly without medical advice.
Possibly, but only under your doctor's supervision. The oral forms and the transdermal patch are not directly interchangeable because they use different dose strengths. Your doctor will determine the appropriate patch strength or oral dose and advise you when and how to switch safely. Do not change formulations on your own.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - EXE0063

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