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compositionComposition:EZETIMIBE-10MG
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Prescription Medicine
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Ezetimide 10mg Tablet is used to treat high cholesterol. It contains Ezetimibe, which effectively lowers the amount of cholesterol in the blood by reducing cholesterol absorption in the intestine and lowering the level of bad cholesterol in the blood. Hence, it reduces the chances of heart disease and makes them healthier. It may cause common side effects such as abdominal pain, diarrhoea, flatulence, tiredness, joint pain, and respiratory tract infection. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EZETIMIBE-10MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Ezetimide 10mg Tablet

Ezetimide 10mg Tablet is a prescription oral tablet used to lower high blood cholesterol levels. It helps reduce low-density lipoprotein (LDL) or 'bad' cholesterol and total cholesterol in the blood. This medicine is typically prescribed for adults and children who cannot control their cholesterol levels through diet and exercise alone.

For best results, you must take Ezetimide 10mg Tablet consistently every day, exactly as your doctor directs. You can take this tablet with or without food at any time of day. Along with taking this medicine, maintaining a heart-healthy diet low in saturated fats and engaging in regular physical activity are essential to achieve target cholesterol levels.

While taking Ezetimide 10mg Tablet, you may experience mild side effects like diarrhoea, joint pain, or feeling tired. These side effects are often temporary, but you should consult your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness.

Talk to your doctor before starting Ezetimide 10mg Tablet if you have a history of liver disease or kidney issues. Do not take this medicine if you have active liver disease or unexplained abnormal liver function tests, especially if you are taking it along with a statin medication.

This medicine can interact with certain blood thinners, immunosuppressants, or other cholesterol-lowering drugs, potentially affecting how they work. If you are pregnant, planning to become pregnant, breastfeeding, or an elderly individual, consult your healthcare provider to discuss whether this medicine is safe for you.

Uses of Ezetimide 10mg Tablet

Ezetimide 10mg Tablet is used to lower high blood cholesterol levels. The detailed uses of Ezetimide 10mg Tablet are as follows:

  • High cholesterol (Primary Hypercholesterolaemia): Ezetimide 10mg Tablet helps reduce elevated levels of total cholesterol, LDL ('bad') cholesterol, and other fats in the blood when diet alone is not enough.
  • Mixed lipid levels (Mixed Hyperlipidaemia): When used alone or with other cholesterol-lowering medicines, Ezetimide 10mg Tablet assists in balancing overall blood fat levels.
  • Inherited high cholesterol (Homozygous Familial Hypercholesterolaemia): In combination with a statin, Ezetimide 10mg Tablet helps lower significantly high cholesterol levels caused by genetic conditions.
  • High plant sterols (Homozygous Sitosterolemia): It helps reduce abnormally high levels of plant sterols in the blood, a rare genetic condition where the body absorbs too much plant fat.
     

Key Benefits

Ezetimide 10mg Tablet helps lower cholesterol levels by reducing the absorption of cholesterol from the digestive tract. By improving blood lipid levels, it supports long-term cardiovascular health and helps reduce the risk of cholesterol-related complications.

  • Helps Lower LDL ('Bad') Cholesterol: By reducing cholesterol absorption in the intestines, Ezetimide 10mg Tablet helps lower low-density lipoprotein (LDL) cholesterol, supporting healthier blood lipid levels.
  • Supports Long-Term Heart Health: By lowering cholesterol levels, Ezetimide 10mg Tablet helps reduce the buildup of fatty deposits in the arteries, decreasing the risk of heart attack, stroke, and other cardiovascular complications.
  • Works Well with Other Cholesterol-Lowering Medicines: Ezetimide 10mg Tablet can be used alone or in combination with statins to provide additional cholesterol reduction, helping patients achieve their target cholesterol levels while supporting effective long-term lipid management.
     
Side effects of Ezetimide 10mg Tablet
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Body pain can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve pain.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening your body.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for constant body pain.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Directions for Use

  • Ezetimide 10mg Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Ezetimide 10mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Ezetimide 10mg Tablet Works

Ezetimide 10mg Tablet contains ezetimibe. It works differently than other cholesterol-lowering medicines that primarily target the liver. It works directly in your digestive tract (the small intestine) to block the absorption of cholesterol from the food you eat and from your body's natural digestive fluids. By preventing cholesterol from being absorbed into your bloodstream, less cholesterol is delivered to your liver. This prompts your liver to pull more cholesterol out of your blood to meet its needs, which successfully lowers your overall circulating blood cholesterol levels.
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Alcohol

Unsafe

Do not drink too much while taking Ezetimide 10mg Tablet. Drinking a lot of alcohol makes you more likely to get muscle and liver side effects.

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Pregnancy

Consult your doctor

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor, and there is no substantial research yet on the use of Ezetimide 10mg Tablet in breastfeeding/nursing mothers. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Safe if prescribed

Ezetimide 10mg Tablet will not affect your ability to drive or operate machinery.

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Liver

Caution

Ezetimide 10mg Tablet to be taken with caution, especially if you have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Ezetimide 10mg Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

Ezetimide 10mg Tablet is not recommended for children below the age of 17 years.

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Heart

Safe if prescribed

Ezetimide 10mg Tablet is generally safe for heart patients if prescribed, but should be used under medical supervision.

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Geriatrics

Safe if prescribed

Ezetimide 10mg Tablet can be given safely to the elderly if advised by the doctor.

What if I have taken an overdose of Ezetimide 10mg Tablet

In case of an accidental overdose, seek immediate medical attention, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Eat a heart-healthy diet: Focus on foods low in saturated fats, trans fats, and cholesterol. Increase your intake of soluble fibre, which is found in oats, beans, lentils, and fruits, as it helps further lower cholesterol.
  • Stay physically active: Aim for at least 150 minutes of moderate-intensity aerobic exercise, like brisk walking or cycling, every week to help raise your 'good' cholesterol and support heart health.
  • Limit high-fat foods: Avoid fried foods, processed meats, full-fat dairy products, and baked goods made with butter or shortening.
  • Avoid smoking and limit alcohol: Quitting smoking improves your cardiovascular health and helps raise your 'good' cholesterol. Restricting alcohol consumption helps manage your overall lipid profile.
     

Have a query?

How Soon It Starts Working

The time required for Ezetimide 10mg Tablet to start to work: The time required for Ezetimide 10mg Tablet to show its action is not clinically established. 

The time for which the effects of Ezetimide 10mg Tablet last: The duration of action for Ezetimide 10mg Tablet is not clinically established.

What if you forget to take Ezetimide 10mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Ezetimide 10mg Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Always check your medication package before use to ensure the tablets are intact and have not changed in appearance.
  • If you are taking cholesterol-binding resins, time your doses carefully to prevent them from stopping Ezetimide 10mg Tablet from being absorbed.
  • Keep all appointments for regular blood tests as scheduled by your doctor to monitor your cholesterol levels and check your liver function.
  • Inform every healthcare provider you see, including dentists and specialists, that you are taking Ezetimide 10mg Tablet.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Bile acid sequestrants: May reduce the absorption of Ezetimide 10mg Tablet, making it less effective. Take Ezetimide 10mg Tablet at least 2 hours before or 4 hours after these medicines.
  • Cyclosporine: Taking this medicine with cyclosporine can increase the blood levels of both drugs, requiring close monitoring by your doctor.
  • Fibrates: Combining Ezetimide 10mg Tablet with fibrates may increase the risk of gallstones and elevate the concentration of Ezetimide 10mg Tablet in your body.
     
EzetimibeCerivastatin
Severe

Drug-Drug Interactions

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How does the drug interact with Ezetimide 10mg Tablet:
Combining Ezetimide 10mg Tablet with Pitavastatin can increase the risk of liver damage, and rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Ezetimide 10mg Tablet with Pitavastatin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, exhaustion, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
EzetimibeCerivastatin
Severe
How does the drug interact with Ezetimide 10mg Tablet:
Using Ezetimide 10mg Tablet together with cerivastatin can increase the risk of side effects (liver damage and rhabdomyolysis - a condition that involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
There may be a possibility of interaction between Ezetimide 10mg Tablet and Cerivastatin, but it can be taken if prescribed by a doctor. It's important to keep an eye on your health. If you notice any of these signs - like feeling achy, weak, or having a fever - it's a good idea to reach out to your doctor right away. Other symptoms to watch out for include dark urine, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, or bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ezetimide 10mg Tablet:
Taking Temsirolimus and Ezetimide 10mg Tablet can increase blood levels of cholesterol and triglycerides.

How to manage the interaction:
There may be a possibility of interaction between Ezetimide 10mg Tablet and Temsirolimus, but it can be taken if prescribed by a doctor. If you are taking sirolimus or temsirolimus along with your cholesterol-lowering medications, it is important to regularly check blood cholesterol and triglyceride levels with a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ezetimide 10mg Tablet:
When Ezetimide 10mg Tablet and Fluvastatin are taken together, the body may not get rid of Ezetimide 10mg Tablet as efficiently.

How to manage the interaction:
There may be a possibility of interaction between Ezetimide 10mg Tablet and Fluvastatin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EzetimibeVoclosporin
Severe
How does the drug interact with Ezetimide 10mg Tablet:
Taking Ezetimide 10mg Tablet and Voclosporin may increase the blood levels and effects of Ezetimide 10mg Tablet.

How to manage the interaction:
Co-administration of Ezetimide 10mg Tablet with Voclosporin can result in an interaction, but it can be taken if a doctor has advised it. If you start or stop taking voclosporin, doctor may need to adjust the dose of other medications you are taking and keep an eye on your health and test results. If you notice any changes in your condition, make sure to contact a doctor right away." Do not discontinue any medications without consulting a doctor.
EzetimibePravastatin
Severe
How does the drug interact with Ezetimide 10mg Tablet:
Pravastatin can cause higher levels of Ezetimide 10mg Tablet in the blood by reducing its excretion rate.

How to manage the interaction:
Co-administration of Ezetimide 10mg Tablet with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ezetimide 10mg Tablet:
Taking Lovastatin with Ezetimide 10mg Tablet may cause higher levels of Ezetimide 10mg Tablet in the blood.

How to manage the interaction:
Although taking Ezetimide 10mg Tablet and Lovastatin together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
EzetimibeEluxadoline
Severe
How does the drug interact with Ezetimide 10mg Tablet:
When Ezetimide 10mg Tablet and Eluxadoline are taken together, the may increase the blood levels and effects of Ezetimide 10mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Ezetimide 10mg Tablet and Eluxadoline, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ezetimide 10mg Tablet:
Teriflunomide can cause higher levels of Ezetimide 10mg Tablet in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Ezetimide 10mg Tablet with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
EzetimibeClofibride
Severe
How does the drug interact with Ezetimide 10mg Tablet:
Using clofibrate and Ezetimide 10mg Tablet may lead to the formation of gall stones.

How to manage the interaction:
Taking Ezetimide 10mg Tablet with Clofibrate together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms related to cholelithiasis, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No clinically significant food interactions are known with Ezetimide 10mg Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

Ezetimide 10mg Tablet is primarily used to treat high cholesterol.
Ezetimide 10mg Tablet contains Ezetimibe, which is a cholesterol absorption inhibitor. It effectively lowers‚ cholesterol in the blood by reducing cholesterol absorption in the intestine and lowering bad cholesterol levels. Hence, reducing the chances of heart disease and making them healthier.
Ezetimide 10mg Tablet, when used with another cholesterol-lowering medicine, especially statin, can cause an increase in liver enzymes. But if used alone, the chances of increased liver enzymes become very rare.
Ezetimide 10mg Tablet is primarily used to treat blood cholesterol levels, so for best results, avoid food that is high in cholesterol, like chips, burgers, and fried food. Preferably eat a low-fat, low-cholesterol diet like home-cooked food.
People with liver or kidney disease or muscle weakness (myopathy) should avoid taking Ezetimide 10mg Tablet as it might further worsen their condition.
Ezetimide 10mg Tablet may cause side effects such as stomach pain, diarrhoea, feeling tired, flatulence (gas), joint pain and respiratory tract infection. If these side effects persist or worsen, please consult your doctor.
No, Ezetimide 10mg Tablet is not a blood thinner. It is a cholesterol-lowering medication that reduces bad cholesterol levels in the blood and the risk of heart diseases.
You are recommended not to stop taking Ezetimide 10mg Tablet on your own without first consulting your doctor as it may worsen your condition. If you experience any difficulty while using Ezetimide 10mg Tablet, please consult your doctor.
Yes, Ezetimide 10mg Tablet is frequently prescribed alongside statins or other cholesterol-lowering drugs to provide a combined effect. However, always consult your doctor before combining any medications.
No, Ezetimide 10mg Tablet is generally not recommended during pregnancy or breastfeeding, especially if taken with a statin. If you are pregnant or planning to become pregnant, talk to your doctor immediately.
You should contact your doctor right away if you experience unexplained muscle pain, tenderness, or weakness, particularly if you also have a fever or feel unwell, as this can be a sign of a rare but serious muscle condition.
Moderate alcohol consumption is generally acceptable, but excessive drinking can increase your risk of liver issues, especially if Ezetimide 10mg Tablet is taken with a statin. Talk to your doctor about your alcohol intake.
It is highly recommended to take Ezetimide 10mg Tablet at the same time each day to help you remember your dose and maintain a steady level of the medicine in your body. Talk to your pharmacist if you need help setting up a routine.

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Manufacturer/Marketer address

Lupin Ltd, 3rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - EZET628
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