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compositionComposition:FEBUXOSTAT-40MG
prescription
Prescription Medicine
info
Febsmart Tablet 10's
Febsmart Tablet 10's
Febsmart Tablet 10's
Febsmart Tablet 10's
Febsmart Tablet 10's

Febsmart Tablet is used to prevent severe gout attacks or flares. It contains Febuxostat, which reduces the level of uric acid in your body. It may cause common side effects such as nausea, rash, dizziness, diarrhoea, and oedema. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

FEBUXOSTAT-40MG

Manufacturer/Marketer :

Oxygen Pharma Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Febsmart Tablet

Febsmart Tablet is a prescription medication used to manage and lower high levels of uric acid in the blood for people with gout. By controlling uric acid levels, this medication helps prevent painful gout flare-ups and long-term joint damage. It is intended for ongoing, long-term management of gout rather than treating sudden, acute attacks.

To get the best results, you must take Febsmart Tablet consistently once a day, exactly as your doctor directs. You can take this tablet with or without food. Combining this treatment with lifestyle changes, such as drinking plenty of water and limiting high-purine foods, will significantly support your recovery and help prevent future flare-ups.

While taking Febsmart Tablet , some people may experience mild side effects like nausea, joint pain, or temporary skin rashes. If you experience severe symptoms, such as chest pain, sudden numbness, shortness of breath, or signs of severe liver damage, you should seek emergency medical care immediately.

Do not take this if you are allergic to any of its ingredients, or if you are currently taking certain medications that suppress the immune system. Before starting Febsmart Tablet , talk to your doctor if you have a history of heart disease, stroke, kidney problems, or liver problems to ensure this medicine is safe for your specific health profile.

This medication can interact with other drugs, including treatments for asthma and certain cancers, which may increase the risk of severe side effects. It is also important to limit alcohol consumption, as it can worsen gout symptoms. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, talk to your doctor or pharmacist before starting this medication.
 

Uses of Febsmart Tablet

Febsmart Tablet is prescribed to reduce elevated uric acid levels and help prevent complications associated with excess uric acid accumulation, including:

  • Chronic Hyperuricaemia: Helps lower abnormally high levels of uric acid in the blood, reducing the formation of uric acid crystals in joints and tissues.
  • Gout Prevention: Used for the long-term management of gout by helping prevent recurrent gout attacks and reducing the risk of joint damage caused by urate crystal deposits.

Key Benefits

Febsmart Tablet provides several important benefits for individuals with gout and chronic hyperuricaemia, including:

  • Effective Uric Acid Control: Lowers and maintains uric acid levels within the target range, helping prevent crystal formation.
  • Reduced Gout Attacks: Helps decrease the frequency and severity of painful gout flare-ups over time.
  • Protection Against Joint Damage: By reducing urate crystal accumulation, it helps protect joints from long-term inflammation and structural damage.
  • Reduction of Urate Deposits: Long-term treatment may help shrink or dissolve existing urate crystal deposits (tophi) in affected tissues.
  • Lower Risk of Kidney Stones: Reducing uric acid levels may decrease the likelihood of developing uric acid kidney stones.
  • Supports Kidney Health: By controlling excess uric acid, it may help reduce uric acid-related stress on the kidneys.
  • Improved Quality of Life: Better control of gout symptoms can help maintain mobility, physical comfort, and participation in everyday activities.
     
Side effects of Febsmart Tablet
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

To ensure Febsmart Tablet works effectively and safely, follow these instructions carefully: 

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • You can take this medication with or without food, but taking it at the same time each day will help you remember.
  • Always follow your doctor's exact instructions regarding how to take this medicine.
  • Do not stop taking this medication without consulting your doctor, even if you experience a temporary gout flare-up when you first start.
     

How Febsmart Tablet Works

Febsmart Tablet belongs to a group of medicines known as xanthine oxidase inhibitors. It works by blocking a specific enzyme in the body called xanthine oxidase, which is responsible for producing uric acid. By reducing the activity of this enzyme, the medication lowers the overall amount of uric acid your body produces, stopping new crystals from forming in your joints and kidneys.
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Alcohol

Unsafe

You should avoid taking alcohol while taking Febsmart Tablet because alcohol may affect Febsmart Tablet effectiveness.

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Pregnancy

Caution

Febsmart Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

There is limited data on how Febsmart Tablet affects breastfeeding. Please consult your doctor before starting Febsmart Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience sleepiness, blurred vision and numbness or tingling sensations while using Febsmart Tablet . Seek medical attention if the symptoms persist longer.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver disease. Your doctor will weigh the benefits and any potential risks before prescribing Febsmart Tablet .

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Kidney

Caution

Febsmart Tablet should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.

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Children

Unsafe

Febsmart Tablet is not recommended for children below the age of 18 years. The safety and efficacy of Febsmart Tablet have not been established in children due to limited testing of this drug on children.

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Heart

Caution

Febsmart Tablet is not contraindicated for all heart patients; however, it is not recommended for those with a history of significant cardiovascular illness unless no other therapeutic choices are available.

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Geriatrics

Consult your doctor

Limited information is available. Please consult your doctor.

What if I have taken an overdose of Febsmart Tablet

Do not take more than the prescribed dose of Febsmart Tablet as it may cause severe side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay Well Hydrated: Drink at least 8 to 10 glasses of water daily to help your kidneys flush out excess uric acid.
  • Limit Purine-Rich Foods: Limit your intake of purine-rich foods, such as red meat, organ meats, seafood, yeast extracts, and gravies.
  • Avoid Sugary Foods and Drinks: Avoid beverages sweetened with high-fructose corn syrup, as well as sugary snacks, which can trigger gout attacks.
  • Restrict Alcohol Consumption: Limit or avoid alcohol consumption, especially beer, which is known to significantly increase uric acid production.
  • Maintain a Healthy Weight: Maintain a moderate, regular exercise routine to manage your weight, but avoid extreme or rapid weight-loss diets, which can temporarily spike uric acid levels.
     

Have a query?

How Soon It Starts Working

  • The time required for Febsmart Tablet to start to work: Febsmart Tablet ideally shows its action within 1 to 1.5 hours after administration.
  • The time for which the effects of Febsmart Tablet last: The effect of Febsmart Tablet lasts for 24 hours.

What if you forget to take Febsmart Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Keep the tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Store the tablets in their original blister pack or container to protect them from moisture and direct light.

Drug Warnings

  • Temporary Gout Flare-Ups: Keep in mind that gout attacks can temporarily increase when you first start taking Febsmart Tablet . Your doctor may prescribe other temporary medications to manage these flare-ups; do not stop taking Febsmart Tablet if this happens.
  • Regular Blood Monitoring: You will need regular blood tests as directed by your doctor to monitor your uric acid levels and check your liver health.
  • Cardiovascular Safety: Be alert for signs of heart issues, such as chest pain or shortness of breath, and seek immediate medical help if they occur, as this medicine may carry a small risk of serious cardiovascular events.
  • Before Medical or Dental Procedures: Inform your dentist or surgeon that you are taking Febsmart Tablet before scheduling any medical or surgical procedures.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Febsmart Tablet may interact with certain medications, potentially increasing the risk of side effects or affecting treatment outcomes. Inform your doctor about all medicines, supplements, and herbal products you are taking, including:

  • Azathioprine or Mercaptopurine: These medicines should generally not be used with Febsmart Tablet , as it can significantly increase their levels in the body and raise the risk of severe toxicity, including bone marrow suppression.
  • Theophylline: Febsmart Tablet may affect the blood levels of theophylline, requiring careful monitoring and possible dose adjustments.
  • Certain Chemotherapy Medicines: Some medications used to treat cancer may interact with Febsmart Tablet and require close medical supervision.
  • Other Uric Acid-Lowering Medicines: Concurrent use with other gout treatments may require monitoring to ensure appropriate uric acid control and minimise adverse effects.


Drug-Food Interactions

Certain dietary factors may influence gout management while taking Febsmart Tablet . Consider the following precautions:

  • Purine-Rich Foods: Foods such as organ meats, red meat, certain seafood, and other high-purine foods may increase uric acid levels and reduce the overall effectiveness of gout management.
  • Alcohol: Alcohol consumption, particularly beer and spirits, may increase uric acid levels and trigger gout attacks. Limiting alcohol intake is generally recommended.Maintain a Balanced Diet: Following a healthy diet and an adequate hydration plan may help support uric acid control and improve treatment outcomes.


Drug-Disease Interactions

Certain medical conditions may require special precautions or closer monitoring during treatment with Febsmart Tablet . Tell your doctor if you have any of the following:

  • Heart Conditions: Patients with a history of heart attack, stroke, angina, or heart failure may require careful monitoring, as cardiovascular safety should be considered during treatment.
  • Severe Kidney Disease: Impaired kidney function may influence treatment decisions and may require dosage adjustments or closer monitoring.
  • Severe Liver Disease: Liver impairment may affect how the medication is processed and may increase the risk of adverse effects.
  • Thyroid Disorders: Some patients may experience changes in thyroid-related laboratory values, so monitoring may be recommended in individuals with pre-existing thyroid conditions.
  • History of Gout Flares: Gout attacks may temporarily increase when Febsmart Tablet is first started, even though the medication is working to lower uric acid levels.
  • Hypersensitivity Reactions: Patients with a history of severe allergic reactions to Febsmart Tablet or similar medications should avoid its use unless specifically advised by their healthcare provider.
     
FebuxostatAzathioprine
Critical
FebuxostatMercaptopurine
Critical

Drug-Drug Interactions

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FebuxostatAzathioprine
Critical
How does the drug interact with Febsmart Tablet:
Taking azathioprine and Febsmart Tablet together can increase the blood levels of azathioprine

How to manage the interaction:
Taking Azathioprine with Febsmart Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FebuxostatMercaptopurine
Critical
How does the drug interact with Febsmart Tablet:
Coadministration of Mercaptopurine with Febsmart Tablet can increase the blood levels of mercaptopurine.

How to manage the interaction:
Taking Mercaptopurine with Febsmart Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FebuxostatKetoconazole
Severe
How does the drug interact with Febsmart Tablet:
Coadministration of Febsmart Tablet with ketoconazole can increase the risk of liver problems.

How to manage the interaction:
Although taking Febsmart Tablet with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
FebuxostatTeriflunomide
Severe
How does the drug interact with Febsmart Tablet:
Coadministration of Teriflunomide with Febsmart Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Febsmart Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
FebuxostatLomitapide
Severe
How does the drug interact with Febsmart Tablet:
Coadministration of Febsmart Tablet with lomitapide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febsmart Tablet with Lomitapide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
FebuxostatLeflunomide
Severe
How does the drug interact with Febsmart Tablet:
Coadministration of Febsmart Tablet with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although taking Febsmart Tablet with Leflunomide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
FebuxostatMipomersen
Severe
How does the drug interact with Febsmart Tablet:
Coadministration of Febsmart Tablet with Mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Febsmart Tablet with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

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Therapeutic Class

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FAQs

Febsmart Tablet is used to prevent severe gout attacks or flares. It prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.
Febsmart Tablet is a class of antigout drugs called xanthine oxidase inhibitors. It works by decreasing a high amount of uric acid to the normal level that is made in the body. Febsmart Tablet is used to prevent gout attacks but not to treat them once they occur.
Febsmart Tablet is not recommended if you have heart disease; taking Febsmart Tablet may cause serious heart problems, which can be life-threatening in some cases. So, please consult your doctor before taking Febsmart Tablet .
Do not drive or operate machinery if you experience dizziness or drowsiness while using Febsmart Tablet .
The dose and duration of Febsmart Tablet depend upon your medical condition. It may take several months before Febsmart Tablet begins to prevent gout attacks. Do not stop taking Febsmart Tablet without the advice of your doctor even if you feel better.
It is best taken in the morning. You can take Febsmart Tablet with or without food. Keep taking Febsmart Tablet every day, to prevent gout attacks.
Chronic hyperuricemia is a condition in which serum uric acid levels are higher than normal.
Hyperuricemia occurs when the body produces too much uric acid or when the kidneys are unable to excrete it properly.
Side effects of Febsmart Tablet include nausea, rash, dizziness, diarrhoea, pain, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), and localised swelling due to retention of fluids in tissues (oedema). Most of these side effects may not require medical attention and will gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Febsmart Tablet may cause frequent urination, kidney stones, blood in urine, reduced ability to function properly, and abnormal urine tests. Talk to the doctor if you have any concerns.
You should know that Febsmart Tablet may cause gout flares, cardiovascular events, and liver problems. Inform the doctor if you have kidney or liver problems, a history of heart disease or stroke, or if you are pregnant/breastfeeding.
It begins to lower the uric acid in your blood within a few weeks, but it may take several months of continuous daily use to fully prevent gout attacks. Talk to your doctor if you have questions about your progress.
When you first start lowering uric acid levels, existing crystals in your joints begin to dissolve, which can temporarily trigger a gout flare-up. This is normal and means the medicine is working. Talk to your doctor about temporary pain-relief options for these initial weeks.
It is highly recommended to limit or avoid alcohol, especially beer. Alcohol increases uric acid production and slows down its removal from your body, which can trigger gout attacks and reduce the effectiveness of your treatment. Talk to your doctor about safe limits.
The safety of this medication in pregnant or breastfeeding women has not been fully established. It is generally not recommended unless your doctor determines that the benefits outweigh the risks. Talk to your doctor or pharmacist for personalised advice.
Yes, pain relievers are frequently prescribed alongside Febsmart Tablet , especially during the first few months of treatment, to manage temporary gout flares. However, you should always talk to your doctor or pharmacist before starting any new medications.
This medicine is generally considered safe for people with mild to moderate kidney disease, and often does not require a dose adjustment. However, if you have severe kidney problems, you must talk to your doctor to determine if this medication is safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. MedlinePlus. A609020 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Febuxostat Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Febuxostat Febuxostat. 2008. [Accessed on 25 Jan. 2019] Check here
  5. Febuxostat Febuxostat. 2009. [Accessed on 02 Apr. 2019] Check here
  6. Thornton & Ross Ltd. Febuxostat 80 mg Film-Coated Tablets: Summary of Product Characteristics [Internet]. London: electronic Medicines Compendium (emc); [Accessed on 2025 Sep 16] Check here
  7. Mayo Clinic Staff. Gout diet: What's allowed, what's not [Internet]. Rochester (MN): Mayo Clinic; [Accessed on 2025 Sep 16]Check here

Country of origin

INDIA

Manufacturer/Marketer address

16-2-674/8/2, Judges Colony, Malakpet, Hyderabad ? 500036
Other Info - FEB0098

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