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compositionComposition:IBUPROFEN-100MG+PARACETAMOL-162.5MG
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Prescription Medicine
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Fenceta Plus Syrup is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. It contains Ibuprofen and Paracetamol, which work by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. It may cause side effects such as tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IBUPROFEN-100MG+PARACETAMOL-162.5MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Fenceta Plus Syrup

Fenceta Plus Syrup is a prescription medicine used to relieve mild to moderate pain and reduce fever. It combines ibuprofen and paracetamol, two medicines that work through different mechanisms to provide effective pain relief and temperature control. It is commonly used for headaches, toothaches, muscle pain, back pain, joint discomfort, menstrual cramps, and fever associated with infections or other illnesses.

Take Fenceta Plus Syrup exactly as prescribed by your doctor. Depending on your condition, it may be taken when needed for symptom relief or on a regular schedule for short-term management of pain. Taking the medicine with food or milk may help reduce stomach irritation. Adequate rest, proper hydration, and maintaining a healthy lifestyle can also support recovery.

Some people may experience mild side effects such as nausea, stomach discomfort, heartburn, or dizziness. These effects are usually temporary and may improve as your body adjusts to the medicine. However, seek medical attention if you develop severe stomach pain, vomiting blood, black stools, difficulty breathing, severe skin reactions, or signs of liver problems.

Before taking Fenceta Plus Syrup, inform your doctor if you have a history of stomach ulcers, gastrointestinal bleeding, kidney disease, liver disease, heart disease, high blood pressure, or asthma. This medicine may not be suitable for people with severe liver impairment, active stomach bleeding, or known allergies to ibuprofen, paracetamol, or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Avoid excessive alcohol consumption while taking this medicine, as alcohol may increase the risk of stomach bleeding and liver-related side effects. Tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are older than 65 years, so they can determine whether this medicine is appropriate for you.
 

Uses of Fenceta Plus Syrup

Fenceta Plus Syrup is used to relieve pain and reduce fever. The detailed uses of Fenceta Plus Syrup are as follows:

  • Mild to Moderate Pain: Helps relieve headaches, toothaches, muscle pain, sprains, strains, and other common painful conditions.
  • Fever Reduction: Helps lower elevated body temperature associated with infections and other illnesses.
  • Joint and Back Pain: Helps reduce discomfort and inflammation associated with musculoskeletal conditions.
  • Menstrual Pain: Helps relieve abdominal cramps and discomfort associated with menstruation.
  • Post-Procedural or Dental Pain: May be prescribed for short-term pain relief following certain medical or dental procedures.
     

Key Benefits

Fenceta Plus Syrup provides effective relief from pain and fever by combining two complementary medicines in a single treatment. This combination may offer greater symptom relief than either ingredient alone for some individuals.

  • Enhanced Pain Relief: Works through multiple pathways to help reduce pain and improve comfort.
  • Reliable Fever Control: Helps lower fever and relieve associated symptoms such as chills and body aches.
  • Improved Physical Function: By reducing pain and discomfort, the medicine may help you perform daily activities more comfortably.
  • Convenient Combination Therapy: Combines two commonly used pain-relieving medicines into a single tablet, simplifying treatment.
     
Side effects of Fenceta Plus Syrup 60 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get urgent medical help if you notice abnormal lung sounds with symptoms, like bluish skin, flare-ups of your nostrils, or trouble breathing.
  • If you have asthma or allergies, managing these conditions with inhalers and bronchodilators can help prevent abnormal lung sounds.
  • Infections may need antibiotics or breathing therapy to help open your airways and make breathing easier.
  • Wash your hands regularly and take other steps to avoid getting sick and spreading germs.
  • Doing breathing exercises can help improve your lung function and make breathing easier.
  • Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
  • Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
  • Omega-3 supplements may support the transport of oxygen to tissues.
  • Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
  • Quit smoking, as it can worsen hypoxia.
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.

Directions for Use

To get the full benefit of Fenceta Plus Syrup and minimise side effects, follow these simple guidelines:

  • Take the tablet orally with a full glass of water.
  • Swallow the tablet whole unless your doctor advises otherwise.
  • Take the medicine with food or milk if stomach irritation occurs.
  • Do not exceed the prescribed dose or recommended duration of treatment.
  • Avoid taking other medicines containing paracetamol or ibuprofen unless advised by your doctor.
  • Always follow your doctor's exact instructions regarding dosage and duration of treatment.
     

How Fenceta Plus Syrup Works

Fenceta Plus Syrup contains ibuprofen and paracetamol. Together, these medicines help relieve pain and reduce fever through complementary mechanisms. Reduces Pain Signals: Paracetamol acts primarily within the central nervous system to help reduce pain perception and lower fever. Reduces Inflammation: Ibuprofen blocks cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that contribute to pain, swelling, and inflammation. Controls Fever: Both ingredients contribute to lowering elevated body temperature by acting on the body's temperature-regulating mechanisms. By combining these actions, Fenceta Plus Syrup helps provide effective relief from pain and fever.
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Alcohol

Unsafe

Taking Fenceta Plus Syrup with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit intake of alcoholic beverages with Fenceta Plus Syrup.

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Pregnancy

Unsafe

Use of Fenceta Plus Syrup during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby.

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Breast Feeding

Consult your doctor

Take Fenceta Plus Syrup only if prescribed by your doctor.

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Driving

Unsafe

After taking Fenceta Plus Syrup you may notice dizziness, sleepiness, drowsiness or fatigue.

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Liver

Caution

Fenceta Plus Syrup to be taken with caution, especially if you have a history of liver disease. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Fenceta Plus Syrup to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Fenceta Plus Syrup is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

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Heart

Unsafe

Fenceta Plus Syrup should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Fenceta Plus Syrup should be used under caution in geriatric patients as it can lead to serious side effects.

What if I have taken an overdose of Fenceta Plus Syrup

Do not take more than the prescribed dose of Fenceta Plus Syrup as it may cause severe side effects. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid Excessive Alcohol Consumption: Alcohol may increase the risk of stomach bleeding and liver-related complications.
  • Stay Well Hydrated: Drinking adequate fluids supports kidney function, especially during fever or illness.
  • Get Adequate Rest: Rest allows your body to recover more effectively from illness or injury.
  • Use Supportive Measures: Warm or cold compresses may help relieve muscle aches, joint discomfort, or minor injuries.
  • Maintain a Healthy Lifestyle: Regular exercise, balanced nutrition, and proper sleep habits may help reduce the frequency of certain pain conditions.
     
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Have a query?

How Soon It Starts Working

The time required for Fenceta Plus Syrup to start to work: The time required for Fenceta Plus Syrup to show its action is unknown. 

The time for which the effects of Fenceta Plus Syrup last: The duration of action for Fenceta Plus Syrup is unknown.

What if you forget to take Fenceta Plus Syrup

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store Fenceta Plus Syrup at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).. •Keep the tablets in their original packaging to protect them from moisture and light.

Drug Warnings

  • Check Other Medicines Carefully: Many cold, flu, and pain medicines may contain paracetamol or NSAIDs. Avoid accidental duplication of ingredients.
  • Do Not Exceed Recommended Doses: Taking more than the prescribed amount may increase the risk of serious liver, kidney, or stomach complications.
  • Watch for Signs of Bleeding: Seek medical advice if you notice unusual bruising, prolonged bleeding, black stools, or blood in vomit.
  • Monitor Liver Health: Inform your doctor if you have liver disease or consume alcohol regularly.
  • Use for the Shortest Necessary Duration: Prolonged use should only occur under medical supervision.
     

Drug-Drug Interactions

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Drug-Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact with Fenceta Plus Syrup:

  • Blood Thinners: Medicines such as warfarin may increase the risk of bleeding.
  • Other NSAIDs: Medicines such as naproxen, diclofenac, or aspirin may increase the risk of stomach ulcers, bleeding, and kidney problems.
  • Blood Pressure Medicines: Certain medicines used to treat high blood pressure may become less effective, and kidney function may require monitoring.
  • Corticosteroids: Medicines such as prednisone may increase the risk of gastrointestinal bleeding.
  • Other Paracetamol-Containing Medicines: Concurrent use may increase the risk of overdose and liver toxicity.


Drug-Food Interactions

  • Alcohol: Excessive alcohol consumption may increase the risk of liver damage and gastrointestinal bleeding.


Drug-Disease Interactions


Inform your doctor if you have a history of the following conditions before taking Fenceta Plus Syrup, as it may worsen your condition or require additional monitoring:

  • Liver Disease: May increase the risk of liver toxicity.
  • Kidney Disease: May increase the risk of kidney-related complications.
  • Active Stomach Ulcers or Gastrointestinal Bleeding: Ibuprofen may worsen these conditions.
  • Heart Failure or Cardiovascular Disease: NSAIDs may increase fluid retention and cardiovascular risks in some individuals.
  • Asthma: Some people with asthma may experience worsening symptoms after taking NSAIDs.
     
Ibuprofen + ParacetamolMeloxicam
Critical
Ibuprofen + ParacetamolKetorolac
Critical

Drug-Drug Interactions

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Ibuprofen + ParacetamolMeloxicam
Critical
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of meloxicam and ibuprofen can increase the risk of side effects such as inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between meloxicam and ibuprofen, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolKetorolac
Critical
How does the drug interact with Fenceta Plus Syrup 60 ml:
Taking ketorolac with ibuprofen can increase the risk of side effects in inflammation, bleeding, and ulceration.

How to manage the interaction:
Although there is an interaction between ketorolac and ibuprofen, it can be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolDiclofenac
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Taking diclofenac with ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is an interaction between diclofenac and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolDasatinib
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of dasatinib and ibuprofen can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between dasatinib and ibuprofen, it can be taken if advised by your doctor. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolTenofovir disoproxil
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of tenofovir disoproxil and ibuprofen can increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between tenofovir disoproxil and ibuprofen, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, sudden weight gain or weight loss, shortness of breath, muscle cramps, weakness, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolRivaroxaban
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Co-administration of rivaroxaban and ibuprofen can increase the risk of bleeding problems.

How to manage the interaction:
Although there is an interaction between rivaroxaban and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolEthanol
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of Fenceta Plus Syrup 60 ml with ethanol can increase the risk of paracetamol-related liver side effects as well as the risk of ibuprofen-related stomach bleeding.

How to manage the interaction:
Although there is an interaction between Fenceta Plus Syrup 60 ml and ethanol, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding, skin rash or itching, nausea, vomiting, or yellowing of the skin, black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. Do not discontinue any medications without consulting a doctor.
Ibuprofen + ParacetamolMethotrexate
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of methotrexate with ibuprofen can increase the effect and side effects of methotrexate.

How to manage the interaction:
Although there is an interaction between methotrexate and ibuprofen, they can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, diarrhea, rash, less desire to eat, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, dizziness or fainting, unusual bruising or bleeding, consult a doctor immediately. Do not stop using medications without a doctor's advice.
Ibuprofen + ParacetamolPrasugrel
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Co-administration of prasugrel and ibuprofen can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between prasugrel and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Ibuprofen + ParacetamolTinzaparin
Severe
How does the drug interact with Fenceta Plus Syrup 60 ml:
Coadministration of tinzaparin and ibuprofen can increase the risk of bleeding complications.

How to manage the interaction:
Although there is an interaction between tinzaparin and ibuprofen, it can be taken if advised by a doctor. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Fenceta Plus Syrup is used to relieve symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever.
Fenceta Plus Syrup is comprised of two medications, Ibuprofen and Paracetamol. Fenceta Plus Syrup has analgesic and anti-inflammatory properties that help relieve mild to moderate pain. Fenceta Plus Syrup functions by inhibiting the production of specific chemical messengers that induce fever, discomfort, and inflammation (redness and swelling).
No, it is not advisable to take Fenceta Plus Syrup with depression medication. Please inform your doctor if you are taking depression medicine before starting Fenceta Plus Syrup.
Yes, Fenceta Plus Syrup is a short term medication and if you feel better you can stop taking Fenceta Plus Syrup, but only after consulting your doctor.
Fenceta Plus Syrup is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.
Yes, Fenceta Plus Syrup may cause dizziness, light-headedness, and occasionally drowsiness in some people. If these symptoms occur, avoid driving, operating machinery, or performing tasks that require alertness until you feel better. Consult your doctor if symptoms persist or worsen.
No, Fenceta Plus Syrup is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take Fenceta Plus Syrup in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.
Consult your doctor before taking other pain relievers, cough medicines, or cold remedies while using Fenceta Plus Syrup. Some products may contain ibuprofen, paracetamol, or similar ingredients, which can increase the risk of accidental overdose and side effects.
No, Fenceta Plus Syrup is generally intended for short-term use unless specifically recommended by your doctor. Long-term or daily use may increase the risk of stomach ulcers, gastrointestinal bleeding, kidney problems, liver problems, and cardiovascular complications. Consult your doctor for appropriate long-term pain management options.
Yes, Fenceta Plus Syrup can be taken on an empty stomach, but taking it with food, milk, or after meals may help reduce the risk of stomach irritation, indigestion, and stomach upset. Consult your doctor if you experience persistent stomach discomfort.
It is best to avoid or limit alcohol consumption while taking this medicine. Alcohol may increase the risk of stomach bleeding and liver-related side effects. Talk to your doctor or pharmacist if you have concerns.
This medicine may not be suitable during pregnancy, particularly during the later stages. Your healthcare provider will determine the safest treatment option based on your individual circumstances. Talk to your doctor or pharmacist before using this medicine during pregnancy.
If your symptoms persist or worsen despite taking the medicine as directed, contact your healthcare provider for further evaluation. Do not increase your dose without medical advice. Talk to your doctor or pharmacist.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.7020 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.1958 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. CiplaMed Clinical Compendium. Ibugesic Plus Oral Suspension Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026]Check here
  4. ScienceDirect ScienceDirect. [Accessed on 23 Apr. 2019]Check here
  5. Acetaminophen and ibuprofen [Prescribing Information]. 2023. [Accessed on 14 Aug. 2024]Check here
  6. Derry CJ, Derry S, Moore RA. Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. Cochrane Database Syst Rev. 2013;2013(6):CD010210. Published 2013 Jun 24. [Accessed on 4 Mar 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - FEN0139

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