Fibator Tablet 10's
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About Fibator Tablet
Fibator Tablet is indicated in the treatment of hyperlipidemia (high lipid levels), mixed dyslipidemia (low good cholesterol and high bad cholesterol and triglycerides), hypercholesterolemia (high cholesterol) and hypertriglyceridemia (high levels of triglycerides).
Fibator Tablet contains atorvastatin and fenofibrate. Atorvastatin reduces cholesterol production in the liver. Fenofibrate works by lowering the level of triglycerides in the blood and bad cholesterol. Together, Fibator Tablet helps treat high cholesterol levels.
In some cases, you may experience side effects like headache, blurred vision, stomach pain, constipation, joint swelling (oedema), joint pain, muscle pain, back pain, and nausea. Most of these side effects of Fibator Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Take Fibator Tablet as prescribed. Your doctor will advise you on how often you take Fibator Tablet based on your medical condition. Fibator Tablet can be taken with or without food with a glass of water. Do not chew, crush or break the medicine.
Inform the doctor if you are allergic to any of the components in Fibator Tablet . If you have hypothyroidism, drink more than 2 servings of alcohol per day, and have a muscle disorder (fibromyalgia), it is advised to inform your doctor before using Fibator Tablet . Immediately contact your doctor if you experience yellowing of the skin (jaundice), allergic reaction, cramps, or muscle weakness. Consult your doctor if you are pregnant or breastfeeding.
Uses of Fibator Tablet
Fibator Tablet is used to manage high lipid levels and lower the risk of cardiovascular problems. The detailed uses of Fibator Tablet are as follows:
- High cholesterol: Fibator Tablet reduces high levels of total cholesterol and LDL (bad cholesterol) in the blood.
- High triglycerides: Fibator Tablet lowers raised triglyceride levels to minimize the risk of pancreatitis and heart disease.
- Dyslipidemia: Fibator Tablet manages abnormal levels of cholesterol and triglycerides together.
- Prevention of heart disease: Fibator Tablet lowers the risk of heart attacks by managing lipid profiles.
- Prevention of blood vessel blockage: Fibator Tablet helps prevent atherosclerosis by reducing plaque buildup in arteries.
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Directions for Use
- It can be taken with or without food as advised by a doctor.
- Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
- Swallow Fibator Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- It helps lower bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in dyslipidemia or hyperlipidemia.
- Fibator Tablet also lowers the amount of fat or cholesterol deposition (plaque) in the arteries of the heart, thereby reducing the chance of having a heart attack or stroke in the future.
- Balances abnormal lipid profiles by lowering triglycerides and LDL while increasing high-density lipoprotein (HDL or 'good cholesterol').
- It increases the uptake and breakdown of LDL cholesterol in the liver. It suppresses the production of very low-density lipoprotein (VLDL), thereby reducing overall bad cholesterol levels in the blood.
- Fibator Tablet enhances the activity of lipoprotein lipase, an enzyme that breaks down fats in the bloodstream. It also helps reduce uric acid levels by promoting its excretion through urine.
- It reduces the chances of complications such as heart attack, stroke, and angina (chest pain due to reduced blood flow to the heart) due to high cholesterol levels.
How Fibator Tablet Works
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- Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
- Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
- If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
- Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
- Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
- Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
- Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
- Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
- Avoid intake of alcohol as it has a direct impact on liver functioning.
- Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
- If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
- Cut down the number of fatty foods that are taken daily.
What if I have taken an overdose of Fibator Tablet
Drug Warnings
- Do not take Fibator Tablet if you are allergic to any of its components.
- A patient should consult a doctor before taking Fibator Tablet if a patient has had a previous stroke with bleeding into the brain or has small pockets of fluid in the brain from previous strokes.
- Also, let your doctor know if you have kidney/liver problems, hypothyroidism, repeated muscle aches or pains, a family history of muscle problems, are older than 70 years, have diabetes, or have problems with certain proteins in your blood.
- Fibator Tablet may increase the risk of muscle problems. Talk to your doctor if you experience muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
- Consult your doctor before starting Fibator Tablet if you are pregnant or breastfeeding.
Drug-Drug Interactions
Drug-Drug Interactions
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Taking Fibator Tablet with Posaconazole can increase the blood levels of Fibator Tablet. This can increase the risk of side effects.
How to manage the interaction:
Although there is an interaction between posaconazole with Fibator Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
When Fibator Tablet is used with cerivastatin, the risk of adverse effects such as liver damage and rhabdomyolysis, an uncommon but serious illness involving the breakdown of skeletal muscle tissue, increases. Rhabdomyolysis can cause kidney damage.
How to manage the interaction:
Although taking Fibator Tablet and Cerivastatin together can cause an interaction, it can be taken if a doctor has suggested it. If you experience unexplained muscular pain, soreness, or weakness while taking these drugs, inform a doctor immediately, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Fibator Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).
How to manage the interaction:
Although taking Fibator Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
Co- administration of Fibator Tablet with Leflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fibator Tablet, can enhance the risk.
How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Fibator Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
co-administration of Fibator Tablet with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.
How to manage the interaction:
Taking Fibator Tablet with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Lomitapide with Fibator Tablet may cause liver damage and using it with other drugs that might adversely impact the liver, such as Fibator Tablet, may enhance the risk.
How to manage the interaction:
There may be a possibility of interaction between Fibator Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
The combined use of Nicotine and Fibator Tablet can increase the blood levels and effects of nicotine. This can increase the risk or severity of side effects.
How to manage the interaction:
Co-administration of Nicotine and Fibator Tablet can lead to an interaction, it can be taken if advised by a doctor. If you experience any symptoms like irritation and burning sensation in the mouth and throat, increased salivation, nausea, abdominal pain, vomiting and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting the doctor.
When atorvastatin is used with Fibator Tablet, it increases the risk of side effects such as liver damage, rhabdomyolosis (uncommon illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Fibator Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
The use of Fibator Tablet and simvastatin can increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue), rhabdomyolysis can cause kidney damage. If you are elderly or have preexisting kidney disease, the risk may increase.
How to manage the interaction:
Co-administration of Fibator Tablet and simvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
When Fibator Tablet is used with pravastatin, it increases the chance of adverse effects such as liver damage and rhabdomyolysis, an uncommon but deadly illness characterised by the destruction of skeletal muscle tissue. Rhabdomyolysis can cause kidney damage.
How to manage the interaction:
Co-administration of Fibator Tablet with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. Inform a doctor immediately, if you have unexplained muscular pain, soreness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, or yellowing of the skin or eyes, consult the doctor immediately.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit Juice
How to manage the interaction:
Blood levels of atorvastatin can rise after consuming grapefruit juice. Before quitting the drug, speak to a doctor even though there may be an interaction. Additionally, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, or yellowing of the skin or eyes, you should consult a doctor. Without first consulting your doctor, never stop taking the medication.
Diet & Lifestyle Advise
- Eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.
- It is best to limit or avoid alcoholic drinks while you are taking this medicine.
- Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
- If you notice slurred speech, confusion, severe weakness or difficulty breathing, contact your health care provider immediately.
- Try aromatherapy, yoga, and meditation to help relax your body and mind.
- Try to do breathing exercises to get more oxygen.
- Eat a healthy diet especially rich in soluble fibers like beans, legumes, whole grains, flax, apples, and citrus fruits.
- Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short period. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
- Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and lower the consumption of red meat.
- Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL.
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Alcohol
Unsafe
Avoid drinking alcohol with Fibator Tablet . It can raise triglyceride levels and may increase your risk of liver damage.
Pregnancy
Unsafe
Fibator Tablet contains Atorvastatin, a pregnancy category X medicine that can harm both the pregnant mother and the unborn baby (fetus). So, please consult your doctor if you are pregnant.
Breast Feeding
Consult your doctor
Fibator Tablet is known to pass into the breast milk and can affect the baby's health. So, please consult your doctor if you are breastfeeding.
Driving
Safe if prescribed
Fibator Tablet does not usually affect your ability to drive.
Liver
Caution
Fibator Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
Kidney
Caution
Fibator Tablet to be taken with caution, especially if you have a history of kidney disease or are currently on dialysis. The dose may have to be adjusted by your doctor.
Children
Caution
Not recommended in children as the safety and efficiency of Fibator Tablet has not been established in children.
Heart
Safe if prescribed
Fibator Tablet can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.
Geriatrics
Consult your doctor
Fibator Tablet should be used in elderly people only if prescribed by the physician.
FAQs
Fibator Tablet is used to treat high lipid levels and reduce the risk of heart diseases. It helps in lowering the bad cholesterol (LDL) and increases the level of good cholesterol (HDL).
Strictly no, a patient is advised to take proper healthy diet free of oily and fatty products recommended by doctor for the best results of this medication.
As such, no harmful interaction has been reported, yet doctor consultation is advised.
This drug is primarily used to lower high levels of fatty acids in blood & to use it for weight loss is only done on a doctor's recommendation after he/she thoroughly checks the state of the patient.
Certain antibiotics like erythromycin and clarithromycin interact with Fibator Tablet and hence should not be used simultaneously with Fibator Tablet unless consulted & recommended by a doctor.
Fibator Tablet may cause side effects like hyperglycemia (high blood sugar), headache, blurred vision, stomach pain, constipation, headaches, joint swelling (oedema), joint pain, muscle pain, back pain, slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.
Liver damage is a very rare side effect of Fibator Tablet . Consult the doctor if you notice signs of liver problems like yellowing of skin and eyes, itchy skin, or dark urine.
Fibator Tablet can cause muscle pain as a side effect. Consult the doctor if you have muscle pain, muscle spasms/cramps or muscle weakness.
Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation.
Consult the doctor before taking Fibator Tablet with other medicines like anticoagulants, anti-gout medicines, antibiotics, antifungals, anti-viral medicines, contraceptive pills, anti-arthritis pills and other fibrates.
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Reference
- https://www.ncbi.nlm.nih.gov/books/NBK430779/\
- https://www.webmd.com/drugs/2/drug-841/atorvastatin-oral/details
- https://www.medicines.org.uk/emc/files/pil.4339.pdf
- https://pubmed.ncbi.nlm.nih.gov/21675801/
- https://www.medicines.org.uk/emc/files/pil.5779.pdf
- https://www.mims.com/india/drug/info/atorvastatin?type=full&mtype=generic
Recommended for a 30-day course: 3 Strips