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compositionComposition:FENOFIBRATE-105MG
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Prescription Medicine
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Fibractiv 105 mg Tablet is used to treat raised or increased cholesterol levels or fat/oils. It contains Fenofibrate, which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases the levels of HDL (good cholesterol). Some people may experience nausea, chest pain, vomiting, diarrhoea, drowsiness, muscle pain, redness/swelling in the legs and increased liver enzymes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FENOFIBRATE-105MG

Manufacturer/Marketer :

Cogentrix Pharma

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Fibractiv 105 mg Tablet

Fibractiv 105 mg Tablet is used to treat increased cholesterol levels or fat/oils. Hyperlipidemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol.

Fibractiv 105 mg Tablet contains fenofibrate, which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol).

Some people may experience nausea, chest pain, vomiting, diarrhoea, drowsiness, muscle pain, redness/swelling in the legs and increased liver enzymes. Most of these side effects of Fibractiv 105 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Fibractiv 105 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using Fibractiv 105 mg Tablet if you are pregnant or breastfeeding. Fibractiv 105 mg Tablet is not recommended for children under the age of 18, as the safety and effectiveness were not established. Avoiding alcohol is recommended to rule out any possibility of side effects.

Uses of Fibractiv 105 mg Tablet

Fibractiv 105 mg Tablet is used to manage high lipid levels and lower the risk of cardiovascular problems. The detailed uses of Fibractiv 105 mg Tablet are as follows:

  • High cholesterol: Fibractiv 105 mg Tablet reduces high levels of total cholesterol and LDL (bad cholesterol) in the blood.
  • High triglycerides: Fibractiv 105 mg Tablet lowers raised triglyceride levels to minimize the risk of pancreatitis and heart disease.
  • Dyslipidemia: Fibractiv 105 mg Tablet manages abnormal levels of cholesterol and triglycerides together.
  • Prevention of heart disease: Fibractiv 105 mg Tablet lowers the risk of heart attacks by managing lipid profiles.
  • Prevention of blood vessel blockage: Fibractiv 105 mg Tablet helps prevent atherosclerosis by reducing plaque buildup in arteries.

Key Benefits

  • Fibractiv 105 mg Tablet contains 'fenofibrate', which is used along with a proper diet to help lower 'bad cholesterol' (LDL, TG -triglycerides) and raise 'good cholesterol' (HDL) in the blood.
  • Fibractiv 105 mg Tablet is also used with statins to lower raised cholesterol.
  • Besides this, Fibractiv 105 mg Tablet also helps in the treatment of raised cholesterol in diabetes and high blood pressure patients as well.
Side effects of Fibractiv 105 mg Tablet
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid smoking and intake of any tobacco products as it worsens respiratory disorders.
  • Get a physical examination, follow your doctor's instructions, and get required vaccinations.
  • Be physically active and eat healthy food.
  • Prefer practising yoga and meditation to reduce stress and anxiety.
  • Practice good hygiene and stay away from places where air pollution is high.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.

Directions for Use

  • Fibractiv 105 mg Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Fibractiv 105 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Fibractiv 105 mg Tablet Works

Fibractiv 105 mg Tablet contains 'fenofibrate', which works by increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases ;levels of HDL (good cholesterol).
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Alcohol

Caution

Avoid drinking alcohol as it can raise liver enzymes and liver functions test (LFT), thereby damaging your liver.

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Pregnancy

Caution

Fibractiv 105 mg Tablet is a Category C risk medicine; talk with your doctor if you’re pregnant or planning to become pregnant. Fibractiv 105 mg Tablet should be used only if the potential benefit justifies the potential risk.

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Breast Feeding

Unsafe

Fibractiv 105 mg Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Fibractiv 105 mg Tablet .

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Driving

Safe if prescribed

Fibractiv 105 mg Tablet does not impact your ability to drive or operate machinery.

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Liver

Caution

Caution is advised. If you have/had liver problems, your doctor may need to monitor your liver function.

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Kidney

Caution

Fibractiv 105 mg Tablet should not be used in severe kidney problems, including in patients on dialysis. However, mild to moderate kidney patients can use Fibractiv 105 mg Tablet if prescribed by the doctor.

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Children

Unsafe

Fibractiv 105 mg Tablet is not recommended for children under the age of 18.

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Heart

Safe if prescribed

Fibractiv 105 mg Tablet is often prescribed to patients with heart problems to manage high cholesterol and reduce cardiovascular risk. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Fibractiv 105 mg Tablet should be used under extreme caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Fibractiv 105 mg Tablet

Do not take more than the prescribed dose of Fibractiv 105 mg Tablet as it may cause unwanted side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eating a proper diet (such as a low-cholesterol/low-fat diet) and other lifestyle changes that may help this medication work better include exercising, losing weight if overweight and stopping smoking.
  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.
  • Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
  • Contact your healthcare provider immediately if you notice slurred speech, confusion, severe weakness or difficulty breathing.
health query

Have a query?

How Soon It Starts Working

  • The time required for Fibractiv 105 mg Tablet to start to work: Fibractiv 105 mg Tablet ideally shows its action within 6 to 8 hours after administration. 
  • The time for which the effects of Fibractiv 105 mg Tablet last: The effect of Fibractiv 105 mg Tablet lasts for 19 to 27 hours.

What if you forget to take Fibractiv 105 mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Before taking the Fibractiv 105 mg Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food.
  • Inform your doctor if you are suffering from bladder problems, gallstones, liver disease, kidney disease, or muscle problems (like muscle pain, myopathy, or rhabdomyolysis). 
  • If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you.
  • Keep your doctor informed about your health condition and all the medicines you are taking before taking Fibractiv 105 mg Tablet to rule out any side effects.
  • Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness.
  • Fibractiv 105 mg Tablet is not recommended in children below 18 years of age.

Drug-Drug Interactions

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Drug-Drug interactions: Fibractiv 105 mg Tablet interacts with oral anticoagulants (coumarin, warfarin), anti-gout medicines (colchicine), and other fibrates (clofibrate, gemfibrozil, ezetimibe).

Drug-Food interactions: Avoid food containing too much fat.

Drug-Disease interactions: Fibractiv 105 mg Tablet should be used with caution in patients with liver problems, gall bladder stones, bladder disease, pancreatitis (inflammation of the pancreas), and muscle problems (myasthenia gravis, rhabdomyolysis).

FenofibratePravastatin
Severe
FenofibrateMipomersen
Severe

Drug-Drug Interactions

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FenofibratePravastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
When Fibractiv 105 mg Tablet is used with pravastatin, it increases the chance of adverse effects such as liver damage and rhabdomyolysis, an uncommon but deadly illness characterised by the destruction of skeletal muscle tissue. Rhabdomyolysis can cause kidney damage.

How to manage the interaction:
Co-administration of Fibractiv 105 mg Tablet with Pravastatin can result in an interaction, but it can be taken if a doctor has advised it. Inform a doctor immediately, if you have unexplained muscular pain, soreness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark-colored urine. Furthermore, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, or yellowing of the skin or eyes, consult the doctor immediately.
FenofibrateMipomersen
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
Mipomersen may cause liver problems and using it with Fibractiv 105 mg Tablet may increase that risk.

How to manage the interaction:
There may be a possibility of interaction between Fibractiv 105 mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.
FenofibrateNicotine
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
The combined use of Nicotine and Fibractiv 105 mg Tablet can increase the blood levels and effects of nicotine. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Nicotine and Fibractiv 105 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. If you experience any symptoms like irritation and burning sensation in the mouth and throat, increased salivation, nausea, abdominal pain, vomiting and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting the doctor.
FenofibrateAtorvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
When atorvastatin is used with Fibractiv 105 mg Tablet, it increases the risk of side effects such as liver damage, rhabdomyolosis (uncommon illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FenofibrateSimvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
The use of Fibractiv 105 mg Tablet and simvastatin can increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue), rhabdomyolysis can cause kidney damage. If you are elderly or have preexisting kidney disease, the risk may increase.

How to manage the interaction:
Co-administration of Fibractiv 105 mg Tablet and simvastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateTeriflunomide
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
Co- administration of Fibractiv 105 mg Tablet with teriflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fibractiv 105 mg Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Teriflunomide and Fibractiv 105 mg Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateDicoumarol
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
co-administration of Fibractiv 105 mg Tablet with dicoumarol can enhance the effects of dicumarol, causing you to bleed more readily.

How to manage the interaction:
Taking Fibractiv 105 mg Tablet with Dicoumarol together can result in an interaction, but it can be taken if a doctor has advised it. If you notice unusual bleeding, bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these medications, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
FenofibrateLeflunomide
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
Co- administration of Fibractiv 105 mg Tablet with Leflunomide can cause liver issues and taking it with other medications that might harm the liver, such as Fibractiv 105 mg Tablet, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Fibractiv 105 mg Tablet, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
FenofibrateAtorvastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
Coadministration of Fibractiv 105 mg Tablet with Atorvastatin can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Fibractiv 105 mg Tablet and atorvastatin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
FenofibratePitavastatin
Severe
How does the drug interact with Fibractiv 105 mg Tablet:
Taking Fibractiv 105 mg Tablet with Pitavastatin can increase the risk of muscle problems like liver damage and rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Fibractiv 105 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience unexpected bruising or bleeding, skin rash, itching, exhaustion, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

Fibractiv 105 mg Tablet is used to treat raised or increased cholesterol levels or fat/oils.
Fibractiv 105 mg Tablet contains fenofibrate, which works by‚ increasing the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, Fibractiv 105 mg Tablet decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases‚ levels of HDL (good cholesterol).
You should not take Fibractiv 105 mg Tablet if you are allergic to fibric acid derivative or Fibractiv 105 mg Tablet , have a severe renal impairment (including dialysis patient), have active liver disease, gallbladder disease (gallstone) or are a nursing mother.
Increased liver enzymes (like liver function tests - LFTs), rhinitis, stuffy/runny nose, nausea, indigestion, headache and back pain are some common side effects that may occur in some cases.
No, Fibractiv 105 mg Tablet does not reduce the risk of having heart problems in patients with type 2 diabetes.
Long-term complications of Fibractiv 105 mg Tablet are muscle problems (like unexplained muscle pain) and liver problems (with increased liver enzymes). So, if you experience these symptoms, please consult a doctor.
Fibractiv 105 mg Tablet raises the risk of muscle pain and a serious muscle problem called rhabdomyolysis. The risk is higher if you take the drug along with statins.
It is completely fine to use oral contraceptives with Fibractiv 105 mg Tablet as no such interactions have been found. Consult your doctor for further advice.
If you forget to take a dose of Fibractiv 105 mg Tablet , take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Do not take more than the prescribed dose of Fibractiv 105 mg Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Avoid drinking alcohol as Fibractiv 105 mg Tablet can raise liver enzymes, thereby damaging your liver.
Periodic monitoring of red and white blood cell counts is recommended during the first 12 months of Fibractiv 105 mg Tablet administration.
Fibractiv 105 mg Tablet may cause liver damage and inflammation after years of use.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

no.3/10, mmtc colony, nanganallur, chennai - 600061
Other Info - FIB0068
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