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  3. Fibrogen-1 Injection 1's

Fibrogen-1 Injection 1's, Pack of 1
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fibrogen-1 Injection is indicated for treating acute bleeding episodes in adults and children with congenital fibrinogen deficiency, including inherited blood disorders such as afibrinogenemia (absence of fibrinogen) and hypofibrinogenemia (low fibrinogen levels). It contains Human Fibrinogen, a protein essential for blood clotting (coagulation). It works by correcting the coagulation defect. Sometimes, this medication may cause side effects such as nausea, vomiting, fever, and thrombocytosis.

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Composition :

HUMAN FIBRINOGEN-1000MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fibrogen-1 Injection

Fibrogen-1 Injection is indicated for treating acute bleeding episodes in adults and children with congenital fibrinogen deficiency, including inherited blood disorders such as afibrinogenemia (absence of fibrinogen) and hypofibrinogenemia (low fibrinogen levels).

Fibrogen-1 Injection contains Human Fibrinogen, a protein important for blood clotting (coagulation). It works by correcting the coagulation defect.

Sometimes, Fibrogen-1 Injection may cause side effects such as nausea, vomiting, fever, and thrombocytosis. These side effects may not require medical attention and resolve over time. However, if the side effects persist or worsen, consult the doctor.

Let the doctor know if you are allergic to any of the components in Fibrogen-1 Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to avoid unpleasant side effects/interactions.

Uses of Fibrogen-1 Injection

Fibrogen-1 Injection is used in the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, such as afibrinogenemia and hypofibrinogenemia. The detailed uses of Fibrogen-1 Injection are as follows:<br/>• Treats congenital fibrinogen deficiency: Fibrogen-1 Injection is used in patients with inherited conditions like afibrinogenemia (absence of fibrinogen) and hypofibrinogenemia (low fibrinogen levels), which impair the body’s ability to form blood clots.<br/>• Controls acute bleeding episodes: Fibrogen-1 Injection helps stabilize the patient by promoting clot formation and stopping blood loss.<br/>• Supports coagulation during surgery or trauma: Fibrogen-1 Injection is used when standard surgical techniques are insufficient to control bleeding, especially in patients with acquired fibrinogen deficiency due to liver disease or disseminated intravascular coagulation (DIC).<br/>• Restores clotting ability: Fibrogen-1 Injection contains human fibrinogen, a key protein that helps form fibrin clots, essential for stopping bleeding and promoting healing.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Fibrogen-1 Injection will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Fibrogen-1 Injection is indicated for the treatment of acute bleeding episodes in adults and children with congenital fibrinogen deficiency, including inherited blood disorders such as afibrinogenemia and hypofibrinogenemia. Fibrogen-1 Injection contains Human Fibrinogen, a protein important for blood clotting (coagulation). It helps correct the coagulation defect.

How Fibrogen-1 Injection Works

Fibrogen-1 Injection contains Human Fibrinogen, a protein important for blood clotting (coagulation). It works by correcting the coagulation defect.

Storage

• Store in a cool and dry place away from sunlight.• Keep Fibrogen-1 Injection out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Fibrogen-1 Injection

As Fibrogen-1 Injection is a parenteral formulation, the chance of overdose may be less. In case of overdose, the risk of abnormal clots in your blood vessels may become increased. In that case, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted.

Drug Warnings

Do not use Fibrogen-1 Injection if you are allergic to any of its components. Inform the doctor if you have/had a heart attack, surgery, liver disease or blood clot problems. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you have any health condition or are taking any medications, including herbal products or vitamin/mineral supplements.

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Cut down on added sugars and salts.
  • Manage stress with meditation and yoga.
  • Exercise regularly.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol affects Fibrogen-1 Injection. Please consult your doctor.

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Pregnancy

Caution

Consult the doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Consult the doctor if you are a nursing mother.

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Driving

Safe

Fibrogen-1 Injection does not influence the ability to drive and use machines. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Fibrogen-1 Injection.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Fibrogen-1 Injection.

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Children

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Fibrogen-1 Injection in children.

Have a query?

FAQs

Fibrogen-1 Injection is used to treat acute bleeding episodes in patients with congenital fibrinogen deficiency, such as afibrinogenemia and hypofibrinogenemia.

Fibrogen-1 Injection works by correcting the coagulation defect. Thereby, it helps arrest bleeding.

Fibrogen-1 Injection is not indicated in the treatment of dysfibrinogenemia, a coagulation disorder characterised by having an abnormal form of fibrinogen.

Fibrogen-1 Injection may cause fever as a side effect. If the condition persists or worsens, consult the doctor.

Fibrogen-1 Injection contains fibrinogen, a protein that helps platelets stick together and form a clot. While fibrinogen does not directly activate platelets, it supports platelet aggregation by binding to a receptor (called GPIIb-IIIa) on activated platelets. This binding helps platelets stick together and form a more substantial clot.

No, Fibrogen-1 Injection is not an insoluble plasma protein. It contains fibrinogen, a soluble protein the liver makes and is found in the blood plasma. Fibrinogen remains soluble in the blood until it is turned into insoluble fibrin to help form a clot.

No, fibrinogen is not typically found in serum. It is usually present in plasma. During the clotting process, fibrinogen is used and converted into fibrin, which forms a clot. After the clot is removed, the remaining liquid is called serum, which does not contain fibrinogen. On the other hand, plasma still contains fibrinogen because it has not undergone clotting.

No, Fibrogen-1 Injection is not a formed element in blood. It is a medication containing fibrinogen, a protein produced in the liver and found in the blood during bleeding in blood vessels, where it helps with clotting. The formed elements in blood are red blood cells, white blood cells, and platelets.

Fibrogen-1 Injection may cause common side effects such as nausea, vomiting, fever, and thrombocytosis in some people. These side effects do not require medical attention and often resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - FIB0124

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:19 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.10315.pdf
  2. https://www.fda.gov/media/105864/download
  3. https://www.nps.org.au/assets/medicines/641a788c-17a9-443e-9c2c-a53300ff6b3c.pdf
  4. https://www.intaspharma.com/wp-content/uploads/2021/12/Fibrogen-I-AW-050-01.pdf

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