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compositionComposition:FLURBIPROFEN-0.03%W/V
prescription
Prescription Medicine
info
Flubifen Eye Drops 5 ml
Flubifen Eye Drops 5 ml contains flurbiprofen which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. This medicine helps prevent pupil of the eye from narrowing. It also prevents intraoperative miosis (decreased pupil size) during surgery.
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

FLURBIPROFEN-0.03%W/V

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

Ophthalmic

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Flubifen Eye Drops 5 ml

Flubifen Eye Drops 5 ml belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs) used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. It also prevents intraoperative miosis (decreased pupil size) during surgery.

Flubifen Eye Drops 5 ml is composed of Flurbiprofen, an ophthalmic anti-inflammatory agent. It works by preventing the pupil of the eye from narrowing, thus making it easier to examine the eye, remove the cataract and replace a new lens by the doctor. It is also used to relieve eye pain and inflammation after surgery.

Flubifen Eye Drops 5 ml is for ophthalmic (for the eye) use only. Common side effects of Flubifen Eye Drops 5 ml include eye redness, irritation, burning or a stinging sensation at the application site, and temporary blurred vision. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Tell your doctor if you are allergic to Flubifen Eye Drops 5 ml or other medications. Avoid contact of the tip of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. If you are pregnant and breastfeeding, inform your doctor before using Flubifen Eye Drops 5 ml. This medicine may cause temporary blurred vision; hence drive only when you are alert and have clear vision. Flubifen Eye Drops 5 ml should be used in children only if advised by a doctor.

Uses of Flubifen Eye Drops 5 ml

Flubifen Eye Drops 5 ml is used for the prevention of intraoperative miosis and the treatment of post-operative eye pain and inflammation. The detailed uses of Flubifen Eye Drops 5 ml are as follows:

  • Prevents pupil constriction during surgery: Flubifen Eye Drops 5 ml helps maintain pupil dilation (prevents miosis) during eye surgeries like cataract procedures, ensuring better surgical visibility.
  • Reduces post-operative eye pain: Flubifen Eye Drops 5 ml minimizes discomfort and pain that can occur after eye surgeries.
  • Controls inflammation: Flubifen Eye Drops 5 ml helps decrease swelling and inflammation in the eye following surgical procedures, promoting smoother recovery.

Key Benefits

Flubifen Eye Drops 5 ml contains Flurbiprofen which prevents the pupil of the eye from narrowing, thus making it easier for the eye examination to remove the cataract and replace a new lens by the doctor. It is a non-steroidal anti-inflammatory drug that inhibits prostaglandins and maintains intraoperative pupil dilation (widening). It further relieves pain and inflammation of the eye after surgery.

Directions for Use

  • Flubifen Eye Drops 5 ml is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Before using eye drops, wash your hands thoroughly. Then, tilt your head back, gently pull down your lower eyelid to create a small pocket, and drop the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.

How Flubifen Eye Drops 5 ml Works

Flubifen Eye Drops 5 ml is composed of Flurbiprofen, an ophthalmic anti-inflammatory agent. It works by preventing the pupil of the eye from narrowing, thus making it easier to examine the eye, remove the cataract and replace a new lens by the doctor. It is also used to relieve eye pain and inflammation after surgery.
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Alcohol

Caution

There is limited information on how alcohol consumption affects Flubifen Eye Drops 5 ml. Please consult your doctor before using Flubifen Eye Drops 5 ml.

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Pregnancy

Caution

If you plan to conceive or are already pregnant, inform your doctor before using Flubifen Eye Drops 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, please consult your doctor before using Flubifen Eye Drops 5 ml.

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Driving

Caution

Flubifen Eye Drops 5 ml may cause side effects like blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have a clear vision

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Liver

Caution

Let your doctor know if you have any history of liver diseases before instilling Flubifen Eye Drops 5 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before instilling Flubifen Eye Drops 5 ml.

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Children

Caution

Flubifen Eye Drops 5 ml can be used in children only when advised by a doctor.

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Heart

Caution

Flubifen Eye Drops 5 ml may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Flubifen Eye Drops 5 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Flubifen Eye Drops 5 ml to geriatric patients. Your doctor will prescribe Flubifen Eye Drops 5 ml if the benefits outweigh the risks.

What if I have taken an overdose of Flubifen Eye Drops 5 ml

An overdose of Flubifen Eye Drops 5 ml may cause stinging or burning of the eyes, and an increase or decrease in pupil size (dark area in the centre of the eye). Use this medicine as prescribed. Seek emergency medical help if an overdose is suspected.

Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always wash your hands before inserting and removing the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.

Have a query?

How Soon It Starts Working

The time required for Flubifen Eye Drops 5 ml to start to work: The onset time of Flubifen Eye Drops 5 ml has not been clinically established. The time for which the effects of Flubifen Eye Drops 5 ml last: The duration of Flubifen Eye Drops 5 ml’s effect is clinically not established.

What if you forget to take Flubifen Eye Drops 5 ml

If you miss a dose, use it as soon as you remember, unless it's almost time for your next dose. Do not double the dose. Continue with your regular schedule.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you have allergic reactions to medicines/NSAIDs (sneezing, runny or stuffy nose, or wheezing), asthma, viral eye infections, and bleeding and blood clotting problems, inform your doctor before starting Flubifen Eye Drops 5 ml. It is advised to check with your doctor before using Flubifen Eye Drops 5 ml if you are pregnant or breastfeeding. Avoid driving or operating machines until you have a clear vision since the administration of Flubifen Eye Drops 5 ml may cause temporary blurred vision for a while.

Drug-Drug Interactions

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Drug-Drug Interaction: Flubifen Eye Drops 5 ml may interact with anti-platelet drugs (clopidogrel), blood thinners (warfarin, enoxaparin), and corticosteroids (prednisone).

Drug-Food Interaction: No drug-food interactions were found.

Drug-Disease Interaction: Brief your doctor if you have a medical history of allergic reactions to medicines/NSAIDs (sneezing, runny or stuffy nose, or wheezing), asthma, viral eye infections, and bleeding and blood clotting problems before starting Flubifen Eye Drops 5 ml.

FlurbiprofenKetorolac
Critical
FlurbiprofenKetorolac tromethamine
Critical

Drug-Drug Interactions

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FlurbiprofenKetorolac
Critical
How does the drug interact with Flubifen Eye Drops 5 ml:
Taking Ketorolac with Flubifen Eye Drops 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Flubifen Eye Drops 5 ml with Ketorolac is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FlurbiprofenKetorolac tromethamine
Critical
How does the drug interact with Flubifen Eye Drops 5 ml:
Taking Ketorolac with Flubifen Eye Drops 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Flubifen Eye Drops 5 ml with Ketorolac tromethamine is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FlurbiprofenPiroxicam
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Using piroxicam together with Flubifen Eye Drops 5 ml may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding and ulceration.

How to manage the interaction:
Although there is a possible interaction between Flubifen Eye Drops 5 ml and Piroxicam, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FlurbiprofenMetrizamide
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Using Flubifen Eye Drops 5 ml together with metrizamide can increase the risk of kidney problems.

How to manage the interaction:
Although taking Flubifen Eye Drops 5 ml and Metrizamide together can evidently cause an interaction, it can be taken if your doctor has suggested it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to your doctor.
FlurbiprofenIodixanol
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Coadministration of Flubifen Eye Drops 5 ml with Iodixanol can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Flubifen Eye Drops 5 ml with Iodixanol can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
FlurbiprofenEverolimus
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Using Everolimus and Flubifen Eye Drops 5 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Everolimus and Flubifen Eye Drops 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
FlurbiprofenVorapaxar
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Taking Flubifen Eye Drops 5 ml with Vorapaxar can increase the risk of bleeding.

How to manage the interaction:
Taking Flubifen Eye Drops 5 ml with Vorapaxar together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs, it's important to contact your doctor right away: bleeding, pain, swelling, headache, dizziness, weakness, vaginal bleeding, nosebleeds, bleeding gums, bruising, red or brown urine, red or black stools, severe and dangerous bleeding, complications, bleeding, bruising, feeling lightheaded, black or tarry stools, severe headache, bleeding or vomiting. Do not stop using any medications without a doctor's advice.
FlurbiprofenDanaparoid
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Co-administration of Flubifen Eye Drops 5 ml with danaparoid can increase the risk of bleeding complications.

How to manage the interaction:
Although there is a interaction between Flubifen Eye Drops 5 ml and danaparoid, but can be taken together if prescribed by a doctor. However, if you experience bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not stop any medications without consulting a doctor.
FlurbiprofenLomitapide
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Using Flubifen Eye Drops 5 ml together with lomitapide can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Flubifen Eye Drops 5 ml and Lomitapide, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms, it's important to contact your doctor right away: liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, bleeding, fatigue, nausea, vomiting, abdominal pain, or dark urine. Do not stop using any medications without first talking to your doctor.
FlurbiprofenEtodolac
Severe
How does the drug interact with Flubifen Eye Drops 5 ml:
Taking Flubifen Eye Drops 5 ml with Etodolac can increase the risk of side effects (inflammation, bleeding, ulceration, and rarely perforation).

How to manage the interaction:
Taking Etodolac with Flubifen Eye Drops 5 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Flubifen Eye Drops 5 ml is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. It also prevents intraoperative miosis (decreased pupil size) during surgery.
Flubifen Eye Drops 5 ml consists of Flurbiprofen, which inhibits prostaglandins, and maintains intraoperative pupil dilation. It prevents the pupil of the eye from narrowing, thus making it easier to perform eye surgery.
If you are wearing contact lenses, remove them while using Flubifen Eye Drops 5 ml. Also, remember to wash your hands before and after using the medicine to avoid contamination.
If you use other eye ointments/drops along with Flubifen Eye Drops 5 ml, it is advised to maintain a gap of at least 5-10 minutes between each medicine. Also, use eye drops before applying any ointments.
Avoid contact of the tip of the dispensing container with fingers, eyes, and eyelids when you use any eye formulation to prevent contamination of the medicine.
Flubifen Eye Drops 5 ml should be used for babies only if prescribed by a doctor. Do not give any medicine to babies without consulting a pediatrician.
Flubifen Eye Drops 5 ml may cause blurry vision temporarily. However, if this condition persists or worsens, consult your doctor.
No, Flubifen Eye Drops 5 ml need not be refrigerated and can be stored at room temperature
Use Flubifen Eye Drops 5 ml as frequently as advised by the doctor. Do not take more or less of Flubifen Eye Drops 5 ml or more often than prescribed as it may cause unwanted effects. Please, consult the doctor if you do not observe any improvement upon using recommended dosages.
No, Flubifen Eye Drops 5 ml is not an antibiotic or a steroid. It belongs to the class of medicines called NSAIDs (Non-steroidal Anti Inflammatory Drugs).
Flubifen Eye Drops 5 ml relieves eye pain and inflammation after surgery. However, it should be used only if advised by a doctor.
Let your doctor know if you are allergic to Flubifen Eye Drops 5 ml or any other medications. Also, inform them if you are pregnant, breastfeeding, or have a history of allergies (especially to NSAIDs), asthma, viral eye infections, or issues with bleeding and clotting before starting Flubifen Eye Drops 5 ml.
If Flubifen Eye Drops 5 ml are prescribed for a condition linked to long-term pain, continue using them as directed by your doctor. For short-term pain, they can be stopped once your pain is relieved. Following your doctor’s advice.
Flubifen Eye Drops 5 ml are generally safe when used in the dose and duration advised by a doctor. Do not use more than the recommended dose
Flubifen Eye Drops 5 ml may cause side effects such as stinging or burning sensation of the eyes, and an increase or decrease in the size of the pupil, redness of the eye, and temporary blurred vision. If these side effects persist or worsen, consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Flurbiprofen Ophthalmic Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.1343 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Flurbiprofen Flurbiprofen. [Accessed on 02 Apr. 2019] Check here
  5. Flurbiprofen Sodium Flurbiprofen Sodium. [Accessed on 10 Feb. 2026] Check here
  6. Ahuja M, Dhake AS, Sharma SK, Majumdar DK. Topical ocular delivery of NSAIDs. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2008. [Accessed on 21st July 2022].Check here

Country of origin

INDIA

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - FLU0414

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